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2004

Journal Article

Cardiovascular actions of human urotensin II - considerations for hypertension

Russell, F. D. and Molenaar, P. (2004). Cardiovascular actions of human urotensin II - considerations for hypertension. Naunyn-Schmiedebergs Archives of Pharmacology, 369 (3), 271-273. doi: 10.1007/s00210-004-0876-y

Cardiovascular actions of human urotensin II - considerations for hypertension

2004

Conference Publication

Investigation of urotensin-II converting enzyme activity in human cells and blood

Kearns, P., Russell, F. D., Toth, I. and Molenaar, P. (2004). Investigation of urotensin-II converting enzyme activity in human cells and blood. 8th Annual Scientific Sessions of the Latin American Section of the International-Society for Heart Research, Brisbane, Qld, Australia, 7th - 11th August, 2004. United Kingdom: Academic Press. doi: 10.1016/j.yjmcc.2004.05.003

Investigation of urotensin-II converting enzyme activity in human cells and blood

2004

Conference Publication

Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium

Russell, F. D. and Molenaar, P. (2004). Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium. 2004 ISHR World Congress Meeting, Brisbane, Qld, Australia, 7 - 11 August, 2004. London, England: Academic Press. doi: 10.1016/j.yjmcc.2004.05.003

Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium

2003

Journal Article

Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptors

Joseph, Shirin S., Lynham, James A., Molenaar, Peter, Grace, Andrew A., Colledge, William H. and Kaumann, Alberto J. (2003). Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptors. Naunyn-Schmiedeberg's Archives of Pharmacology, 368 (6), 496-503. doi: 10.1007/s00210-003-0835-z

Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptors

2003

Journal Article

Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure

Russell, F. D., Meyers, D. E., Galbraith, A., Bett, N., Toth, I., Kearns, P. S. and Molenaar, P. (2003). Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. American Journal of Physiology - Heart & Circulatory Physiology, 285 (Oct.2003), H1576-H1581. doi: 10.1152/ajpheart.00217.2003

Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure

2003

Conference Publication

Activation of calcineurin in explanted human ventricle by endogenous peptides

Li, J., Russell, F. D. and Molenaar, P. (2003). Activation of calcineurin in explanted human ventricle by endogenous peptides. ASCEPT, Sydney, 30 Nov - 3 Dec, 2003. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Activation of calcineurin in explanted human ventricle by endogenous peptides

2003

Journal Article

The 'state' of beta-adrenoceptors

Molenaar, P. (2003). The 'state' of beta-adrenoceptors. British Journal of Pharmacology, 140 (1), 1-2. doi: 10.1038/sj.bjp.0705420

The 'state' of beta-adrenoceptors

2003

Conference Publication

Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium

Russell, F. D. and Molenaar, P. (2003). Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium. ASCEPT, Sydney, 30 Nov - 3 Dec, 2003. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium

2003

Conference Publication

Intrinsic sympathomimetic activity (ISA) of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human right atrium

Molenaar, P. and Kaumann, A. J. (2003). Intrinsic sympathomimetic activity (ISA) of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human right atrium. ASCEPT, Sydney, 30 Nov - 3 Dec, 2003. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Intrinsic sympathomimetic activity (ISA) of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human right atrium

2003

Journal Article

(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor

Sarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., Li, Li, Kaumann, Alberto J. and Molenaar, Peter (2003). (-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor. Naunyn-Schmiedeberg's Archives of Pharmacology, 367 (1), 10-21. doi: 10.1007/s00210-002-0652-9

(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor

2002

Conference Publication

The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium

Molenaar, P., Russell, F. D., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L. and West, M. J. (2002). The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium. American Heart Association Scientific Sessions 2002, Chicago, 17-20 Nov, 2002. Hagerstown, U.S.A.: Lippincott Williams & Wilkins.

The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium

2002

Journal Article

Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro

Molenaar, P., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L., West, M. J. and Russell, F. D. (2002). Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro. Journal of The American College of Cardiology, 40 (7), 1275-1282. doi: 10.1016/S0735-1097(02)02137-X

Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro

2002

Journal Article

(-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.

Kaumann, AJ, Lynham, JA, Joseph, SS, Colledge, WH, Grace, AA and Molenaar, P (2002). (-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.. British Journal of Pharmacology, 135

(-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.

2001

Journal Article

Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacology

Kaumann, AJ, Engelhardt, S, Hein, L, Molenaar, P and Lohse, M (2001). Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacology. Naunyn-schmiedebergs Archives of Pharmacology, 363 (1), 87-93. doi: 10.1007/s002100000336

Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacology

2001

Edited Outputs

Proceedings of the Australian Society for Medical Research

P. Molenaar, F. D. Russell, G. C. Rabnott, I. Yang, K. M. Fong and M. J. West eds. (2001). Proceedings of the Australian Society for Medical Research. BioInnovation: The Future of Medical Research, Gold Coast, Queensland, Australia, 24 - 27 November, 2001. Australia: Australian Society for Medical Research.

Proceedings of the Australian Society for Medical Research

2001

Journal Article

Cardiostimulant effects of urotensin-II in human heart in vitro

Russell, FD, Molenaar, P and O'Brien, DM (2001). Cardiostimulant effects of urotensin-II in human heart in vitro. British Journal of Pharmacology, 132 (1), 5-9. doi: 10.1038/sj.bjp.0703811

Cardiostimulant effects of urotensin-II in human heart in vitro

2001

Journal Article

Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor

Heubach, J. F., Graf, E. M., Molenaar, P., Jager, A., Schroder, F., Herzig, S., Harding, S. E. and Ravens, U. (2001). Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor. British Journal of Pharmacology, 133 (1), 73-82. doi: 10.1038/sj.bjp.0704045

Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor

2000

Journal Article

Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein

Molenaar, P., Bartel, S., Cochrane, A., Vetter, D., Jalali, H., Pohlner, P., Burrell, K., Karczewski, P, Krause, E. and Kaumann, A. J. (2000). Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein. Circulation, 102 (15), 1814-1821. doi: 10.1161/01.CIR.102.15.1814

Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein

2000

Journal Article

Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout mice

Oostendorp, J., Preitner, F., Moffatt, J., Jimenez, M., Giacobino, J. P., Molenaar, P. and Kaumann, A. J. (2000). Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout mice. British Journal of Pharmacology, 130 (4), 747-758. doi: 10.1038/sj.bjp.0703365

Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout mice

2000

Journal Article

The human heart endothelin system: ET-1 synthesis, storage, release and effect

Russell, F. D. and Molenaar, P. (2000). The human heart endothelin system: ET-1 synthesis, storage, release and effect. Trends in Pharmacological Sciences, 21 (9), 353-359. doi: 10.1016/S0165-6147(00)01524-8

The human heart endothelin system: ET-1 synthesis, storage, release and effect