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2000

Conference Publication

Endogenous modulators of human heart contractility

Molenaar, P., Russell, F. D. and Burrell, K. (2000). Endogenous modulators of human heart contractility. ISHR Melbourne Conference 2000: Benchtop Bedside the Beside, Melbourne, Australia, 05-09 Aug, 2000. Melbourne: International Society for Heart Research (Australasian Section).

Endogenous modulators of human heart contractility

2000

Conference Publication

Cardiostimulant effects of human urotensin-II in human heart.

Russell, F. D., Molenaar, P. and O'Brien, D. M. (2000). Cardiostimulant effects of human urotensin-II in human heart.. Joint Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists and the British Pharmacological Society, Newcastle, Australia, 03-06 Dec, 2000. Sydney: Aust Society of Clin & Exp Pharmacologists & Toxicologists.

Cardiostimulant effects of human urotensin-II in human heart.

2000

Journal Article

Quantitative analysis of vascular to cardiac selectivity of L- and T-type voltage-operated calcium channel antagonists in human tissues

Angus, J, Sarsero, D, Fujiwara, T, Molenaar, P and Xi, Q (2000). Quantitative analysis of vascular to cardiac selectivity of L- and T-type voltage-operated calcium channel antagonists in human tissues. Clinical And Experimental Pharmacology And Physiology, 27 (12), 1019-1021. doi: 10.1046/j.1440-1681.2000.03369.x

Quantitative analysis of vascular to cardiac selectivity of L- and T-type voltage-operated calcium channel antagonists in human tissues

2000

Conference Publication

b1-, b2- and putative b4-adrenoceptors (AR) in adult and infant human heart: selective coupling of b2-AR to Gs-protein.

Molenaar, P. and Kaumann, A. J. (2000). b1-, b2- and putative b4-adrenoceptors (AR) in adult and infant human heart: selective coupling of b2-AR to Gs-protein.. Joint Meeting of ASCEPT and the British Pharmacological Society, Newcastle, Australia, 03-06 Dec, 2000. Sydney: Aust Society of Clin. and Exp. Pharmacologists & Toxicologists.

b1-, b2- and putative b4-adrenoceptors (AR) in adult and infant human heart: selective coupling of b2-AR to Gs-protein.

2000

Journal Article

The human heart endothelin system: ET-1 synthesis, storage, release and effect

Russell, F. D. and Molenaar, P. (2000). The human heart endothelin system: ET-1 synthesis, storage, release and effect. Trends in Pharmacological Sciences, 21 (9), 353-359. doi: 10.1016/S0165-6147(00)01524-8

The human heart endothelin system: ET-1 synthesis, storage, release and effect

2000

Conference Publication

(-)-CGP 12177-evoked cardiostimulation is abolished in double b1-/b2-adrenoceptor (AR) knockout mice.

Kaumann, A. J., Engelhardt, S., Molenaar, P. and Lohse, M. (2000). (-)-CGP 12177-evoked cardiostimulation is abolished in double b1-/b2-adrenoceptor (AR) knockout mice.. Joint Meeting of ASCEPT and the British Pharmacological Society, Newcastle, Australia, 03-06 Dec, 2000. Sydney: Aust Society of Clin and Exp Pharmacologists and Toxicologists.

(-)-CGP 12177-evoked cardiostimulation is abolished in double b1-/b2-adrenoceptor (AR) knockout mice.

1999

Journal Article

Activation of beta(2)-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure

Kaumann, A, Bartel, S, Molenaar, P, Sanders, L, Burrell, K, Vetter, D, Hempel, P, Karczewski, P and Krause, EG (1999). Activation of beta(2)-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure. Circulation, 99 (1), 65-72.

Activation of beta(2)-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure

1999

Journal Article

Studies on a novel selective beta(3)-adrenoceptor agonist in human right atrial appendage and human white adipocytes

Arch, JRS, Kaumann, AJ, Molenaar, P, Sennitt, MV, Berge, JM, Chapman, H and Kelly, J (1999). Studies on a novel selective beta(3)-adrenoceptor agonist in human right atrial appendage and human white adipocytes. British Journal of Pharmacology, 126, U55-U55.

Studies on a novel selective beta(3)-adrenoceptor agonist in human right atrial appendage and human white adipocytes

1999

Conference Publication

Contribution of b-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and b3-adrenoceptor knockout mice: Involvement of the putative b4-adrenoceptor

Molenaar, P., Oostendorp, J., Preitner, F., Moffat, J., Jimenez, M., Giacobino, J. P. and Kaumann, A. J. (1999). Contribution of b-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and b3-adrenoceptor knockout mice: Involvement of the putative b4-adrenoceptor. 33rd Annual Scientific Meeting of ASCEPT, Sydney Convention & Exhibition Cen., Darling Harbour, 4 - 8 Dec, 1999. Sydney: Aust. Soc. of Clinical & Experimental Pharm. & Toxicol..

Contribution of b-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and b3-adrenoceptor knockout mice: Involvement of the putative b4-adrenoceptor

1999

Journal Article

Putative beta(4)-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[H-3]-CGP 12177 binding

Sarsero, D., Molenaar, P., Kaumann, A. J. and Freestone, N. S. (1999). Putative beta(4)-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[H-3]-CGP 12177 binding. British Journal of Pharmacology, 128 (7), 1445-1460. doi: 10.1038/sj.bjp.0702936

Putative beta(4)-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[H-3]-CGP 12177 binding

1998

Journal Article

Validity of (-)-[H-3]-CGP 12177A as a radioligand for the 'putative beta(4)-adrenoceptor' in rat atrium

Sarsero, Doreen, Molenaar, Peter and Kaumann, Alberto J. (1998). Validity of (-)-[H-3]-CGP 12177A as a radioligand for the 'putative beta(4)-adrenoceptor' in rat atrium. British Journal of Pharmacology, 123 (3), 371-380. doi: 10.1038/sj.bjp.0701609

Validity of (-)-[H-3]-CGP 12177A as a radioligand for the 'putative beta(4)-adrenoceptor' in rat atrium

1998

Journal Article

Inotropic and arrhythmic effects of endothelin receptor agonists in human heart: Possible involvement of multiple receptors, L-type calcium channels and Gi-protein.

Burrell, KM, Molenaar, P and Kaumann, AJ (1998). Inotropic and arrhythmic effects of endothelin receptor agonists in human heart: Possible involvement of multiple receptors, L-type calcium channels and Gi-protein.. Naunyn-schmiedebergs Archives of Pharmacology, 358 (1), R627-R627.

Inotropic and arrhythmic effects of endothelin receptor agonists in human heart: Possible involvement of multiple receptors, L-type calcium channels and Gi-protein.

1998

Journal Article

(-)-CGP 12177 causes cardiostimulation and binds to cardiac putative beta(4)-adrenoceptors in both wild-type and beta(3)-adrenoceptor knockout mice

Kaumann, AJ, Preitner, F, Sarsero, D, Molenaar, P, Revelli, JP and Giacobino, JP (1998). (-)-CGP 12177 causes cardiostimulation and binds to cardiac putative beta(4)-adrenoceptors in both wild-type and beta(3)-adrenoceptor knockout mice. Molecular Pharmacology, 53 (4), 670-675.

(-)-CGP 12177 causes cardiostimulation and binds to cardiac putative beta(4)-adrenoceptors in both wild-type and beta(3)-adrenoceptor knockout mice

1998

Journal Article

The putative beta(4)-adrenoceptor activates the cyclic AMP pathway in human heart: Inhibition of positive inotropic responses by adenosine and carbachol

Molenaar, P, Sarsero, D, Lynham, JA and Kaumann, AJ (1998). The putative beta(4)-adrenoceptor activates the cyclic AMP pathway in human heart: Inhibition of positive inotropic responses by adenosine and carbachol. Naunyn-schmiedebergs Archives of Pharmacology, 358 (1), R629-R629.

The putative beta(4)-adrenoceptor activates the cyclic AMP pathway in human heart: Inhibition of positive inotropic responses by adenosine and carbachol

1998

Journal Article

Human vascular to cardiac tissue selectivity of L- and T-type calcium channel antagonists

Sarsero, D, Fujiwara, T, Molenaar, P and Angus, JA (1998). Human vascular to cardiac tissue selectivity of L- and T-type calcium channel antagonists. British Journal of Pharmacology, 125 (1), 109-119. doi: 10.1038/sj.bjp.0702045

Human vascular to cardiac tissue selectivity of L- and T-type calcium channel antagonists

1998

Journal Article

The contribution of classical (beta(1/2)-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta(3)-adrenoceptor agonists of differing selectivities

Molenaar, P (1998). The contribution of classical (beta(1/2)-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta(3)-adrenoceptor agonists of differing selectivities. Journal of Pharmacology And Experimental Therapeutics, 285 (3), 1084-1095.

The contribution of classical (beta(1/2)-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta(3)-adrenoceptor agonists of differing selectivities

1998

Journal Article

(-)-[H-3]-CGP 12177 radiolabels beta(1)-, beta(2)- and putative beta(4)-adrenoceptors in human atrium and ventricle.

Sarsero, D, Molenaar, P and Kaumann, AJ (1998). (-)-[H-3]-CGP 12177 radiolabels beta(1)-, beta(2)- and putative beta(4)-adrenoceptors in human atrium and ventricle.. Naunyn-schmiedebergs Archives of Pharmacology, 358 (1), R629-R629.

(-)-[H-3]-CGP 12177 radiolabels beta(1)-, beta(2)- and putative beta(4)-adrenoceptors in human atrium and ventricle.

1997

Journal Article

Proposal for the interaction of non-conventional partial agonists and catecholamines with the 'putative beta(4)-adrenoceptor' in mammalian heart

Molenaar, P, Sarsero, D and Kaumann, AJ (1997). Proposal for the interaction of non-conventional partial agonists and catecholamines with the 'putative beta(4)-adrenoceptor' in mammalian heart. Clinical And Experimental Pharmacology And Physiology, 24 (9-10), 647-656. doi: 10.1111/j.1440-1681.1997.tb02107.x

Proposal for the interaction of non-conventional partial agonists and catecholamines with the 'putative beta(4)-adrenoceptor' in mammalian heart

1997

Journal Article

Modulation of human cardiac function through 4 beta-adrenoceptor populations

Kaumann, AJ and Molenaar, P (1997). Modulation of human cardiac function through 4 beta-adrenoceptor populations. Naunyn-schmiedebergs Archives of Pharmacology, 355 (6), 667-681. doi: 10.1007/PL00004999

Modulation of human cardiac function through 4 beta-adrenoceptor populations

1997

Journal Article

Effects of (-)-RO363 at human atrial beta-adrenoceptor subtypes, the human cloned beta(3)-adrenoceptor and rodent intestinal beta(3)-adrenoceptors

Molenaar, P, Sarsero, D, Arch, JRS, Kelly, J, Henson, SM and Kaumann, AJ (1997). Effects of (-)-RO363 at human atrial beta-adrenoceptor subtypes, the human cloned beta(3)-adrenoceptor and rodent intestinal beta(3)-adrenoceptors. British Journal of Pharmacology, 120 (2), 165-176. doi: 10.1038/sj.bjp.0700850

Effects of (-)-RO363 at human atrial beta-adrenoceptor subtypes, the human cloned beta(3)-adrenoceptor and rodent intestinal beta(3)-adrenoceptors