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2021 Journal Article Fetal alleles predisposing to metabolically favourable adiposity are associated with higher birth weightThompson, William D., Beaumont, Robin N., Kuang, Alan, Warrington, Nicole M., Ji, Yingjie, Tyrrell, Jess, Wood, Andrew R., Scholtens, Denise, Knight, Bridget A., Evans, David M., Lowe, Bill L., Santorelli, Gillian, Azad, Raq, Mason, Dan, Hattersley, Andrew T., Frayling, Timothy M., Yaghootkar, Hanieh, Borges, Maria-Carolina, Lawlor, Deborah A. and Freathy, Rachel M. (2021). Fetal alleles predisposing to metabolically favourable adiposity are associated with higher birth weight. Human Molecular Genetics, 31 (11), 1762-1775. doi: 10.1093/hmg/ddab356 |
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2021 Conference Publication Methods for Enabling and Improving the Power of Mendelian Randomization Studies of Parental Environmental Exposures and Offspring OutcomesMoen, Gunn-Helen, Bhatta, Laxmi, Asvold, Bjorn Olav, Brumpton, Ben, Warrington, Nicole M. and Evans, David M. (2021). Methods for Enabling and Improving the Power of Mendelian Randomization Studies of Parental Environmental Exposures and Offspring Outcomes. NEW YORK: SPRINGER. |
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2021 Conference Publication Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic healthWang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Asvold, Bjorn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2021). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Behavior Genetics Association 51st Annual Meeting, Online (Zoom), 29 June 2021. New York, United States: Springer. |
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2021 Journal Article Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profileThompson, William D., Beaumont, Robin N., Kuang, Alan, Warrington, Nicole M., Ji, Yingjie, Tyrrell, Jessica, Wood, Andrew R., Scholtens, Denise M., Knight, Bridget A., Evans, David M., Lowe, William L., Santorelli, Gillian, Azad, Rafaq, Mason, Dan, Hattersley, Andrew T., Frayling, Timothy M., Yaghootkar, Hanieh, Borges, Maria Carolina, Lawlor, Deborah A. and Freathy, Rachel M. (2021). Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile. Diabetologia, 64 (12), 2790-2802. doi: 10.1007/s00125-021-05570-9 |
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2021 Journal Article Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results dataWarrington, Nicole M., Hwang, Liang-Dar, Nivard, Michel G. and Evans, David M. (2021). Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data. Nature Communications, 12 (1) 5420, 1-12. doi: 10.1038/s41467-021-25723-z |
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2020 Journal Article Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweightMoen, Gunn-Helen, Beaumont, Robin N., Grarup, Niels, Sommer, Christine, Shields, Beverley M., Lawlor, Deborah A., Freathy, Rachel M., Evans, David M. and Warrington, Nicole M. (2020). Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight. International Journal of Epidemiology, 50 (1), 179-189. doi: 10.1093/ije/dyaa256 |
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2020 Journal Article A cautionary note on using Mendelian randomization to examine the Barker hypothesis and Developmental Origins of Health and Disease (DOHaD)D'Urso, Shannon, Wang, Geng, Hwang, Liang-Dar, Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2020). A cautionary note on using Mendelian randomization to examine the Barker hypothesis and Developmental Origins of Health and Disease (DOHaD). Journal of Developmental Origins of Health and Disease, 12 (5) PII S2040174420001105, 1-6. doi: 10.1017/S2040174420001105 |
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2020 Conference Publication Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study using the OpenMx softwareMoen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Asvold, Bjorn Olav, Birkeland, Kare, Neale, Michael C., Freathy, Rachel M., Smith, George Davey, Lawlor, Deborah A., Kirkpatrick, Robert M., Warrington, Nicole M. and Evans, David M. (2020). Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study using the OpenMx software. 50th Annual Meeting of the Behavior-Genetics-Association (BGA), Electr Network, Jun 26, 2020. NEW YORK: SPRINGER. |
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2020 Journal Article Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairsHwang, Liang-Dar, Tubbs, Justin D., Luong, Justin, Lundberg, Mischa, Moen, Gunn-Helen, Wang, Geng, Warrington, Nicole M., Sham, Pak C., Cuellar-Partida, Gabriel and Evans, David M. (2020). Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs. PLoS Genetics, 16 (10) e1009154, e1009154. doi: 10.1371/journal.pgen.1009154 |
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2020 Journal Article Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohortMoen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Åsvold, Bjørn Olav, Birkeland, Kåre I., Wang, Geng, Neale, Michael C., Freathy, Rachel M., Smith, George Davey, Lawlor, Deborah A., Kirkpatrick, Robert M., Warrington, Nicole M. and Evans, David M. (2020). Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort. Nature Communications, 11 (1) 5404, 5404. doi: 10.1038/s41467-020-19257-z |
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2020 Journal Article Genome-wide association study identifies 48 common genetic variants associated with handednessCuellar-Partida, Gabriel, Tung, Joyce Y., Eriksson, Nicholas, Albrecht, Eva, Aliev, Fazil, Andreassen, Ole A., Barroso, Inês, Beckmann, Jacques S., Boks, Marco P., Boomsma, Dorret I., Boyd, Heather A., Breteler, Monique M. B., Campbell, Harry, Chasman, Daniel I., Cherkas, Lynn F., Davies, Gail, de Geus, Eco J. C., Deary, Ian J., Deloukas, Panos, Dick, Danielle M., Duffy, David L., Eriksson, Johan G., Esko, Tõnu, Feenstra, Bjarke, Geller, Frank, Gieger, Christian, Giegling, Ina, Gordon, Scott D., Han, Jiali ... Medland, Sarah E. (2020). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature Human Behaviour, 5 (1), 59-70. doi: 10.1038/s41562-020-00956-y |
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2020 Other Outputs Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT studyMoen, Gunn-Helen, Brumpton, Ben, Willer, Cristen, Åsvold, Bjørn Olav, Birkeland, Kåre, Neale, Michael C, Freathy, Rachel M, Smith, George Davey, Lawlor, Deborah A, Kirkpatrick, Robert M, Warrington, Nicole M and Evans, David M (2020). Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study. doi: 10.1101/2020.05.04.20091173 |
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2020 Journal Article The effect of plasma lipids and lipid-lowering interventions on bone mineral density: a Mendelian randomization studyZheng, Jie, Brion, Marie-Jo, Kemp, John P., Warrington, Nicole M., Borges, Maria-Carolina, Hemani, Gibran, Richardson, Tom G., Rasheed, Humaira, Qiao, Zhen, Haycock, Philip, Ala-Korpela, Mika, Davey Smith, George, Tobias, Jon H. and Evans, David M. (2020). The effect of plasma lipids and lipid-lowering interventions on bone mineral density: a Mendelian randomization study. Journal of Bone and Mineral Research, 35 (7) jbmr.3989, 1224-1235. doi: 10.1002/jbmr.3989 |
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2020 Journal Article Integrating family-based and Mendelian randomization designsHwang, Liang-Dar, Davies, Neil M., Warrington, Nicole M. and Evans, David M. (2020). Integrating family-based and Mendelian randomization designs. Cold Spring Harbor Perspectives in Medicine, 11 (3) a039503, 1-15. doi: 10.1101/cshperspect.a039503 |
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2019 Journal Article Introducing M-GCTA a software package to estimate maternal (or paternal) genetic effects on offspring phenotypesQiao, Zhen, Zheng, Jie, Helgeland, Øyvind, Vaudel, Marc, Johansson, Stefan, Njølstad, Pål R., Smith, George Davey, Warrington, Nicole M. and Evans, David M. (2019). Introducing M-GCTA a software package to estimate maternal (or paternal) genetic effects on offspring phenotypes. Behavior Genetics, 50 (1), 51-66. doi: 10.1007/s10519-019-09969-4 |
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2019 Journal Article GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMICouto Alves, Alexessander, De Silva, N. Maneka G., Karhunen, Ville, Sovio, Ulla, Das, Shikta, Taal, H. Rob, Warrington, Nicole M., Lewin, Alexandra M., Kaakinen, Marika, Cousminer, Diana L., Thiering, Elisabeth, Timpson, Nicholas J., Bond, Tom A., Lowry, Estelle, Brown, Christopher D., Estivill, Xavier, Lindi, Virpi, Bradfield, Jonathan P., Geller, Frank, Speed, Doug, Coin, Lachlan J. M., Loh, Marie, Barton, Sheila J., Beilin, Lawrence J., Bisgaard, Hans, Bønnelykke, Klaus, Alili, Rohia, Hatoum, Ida J., Schramm, Katharina ... Early Growth Genetics (EGG) Consortium (2019). GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Science Advances, 5 (9) eaaw3095, eaaw3095. doi: 10.1126/sciadv.aaw3095 |
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2019 Journal Article Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weightHwang, Liang-Dar, Lawlor, Deborah A., Freathy, Rachel M., Evans, David M. and Warrington, Nicole M. (2019). Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight. International Journal of Epidemiology, 48 (5), 1457-1467. doi: 10.1093/ije/dyz160 |
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2019 Journal Article Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factorsWarrington, Nicole M., Beaumont, Robin N., Horikoshi, Momoko, Day, Felix R., Helgeland, Øyvind, Laurin, Charles, Bacelis, Jonas, Peng, Shouneng, Hao, Ke, Feenstra, Bjarke, Wood, Andrew R., Mahajan, Anubha, Tyrrell, Jessica, Robertson, Neil R., Rayner, N. William, Qiao, Zhen, Moen, Gunn-Helen, Vaudel, Marc, Marsit, Carmen J., Chen, Jia, Nodzenski, Michael, Schnurr, Theresia M., Zafarmand, Mohammad H., Bradfield, Jonathan P., Grarup, Niels, Kooijman, Marjolein N., Li-Gao, Ruifang, Geller, Frank, Paternoster, Lavinia ... Freathy, Rachel M. (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics, 51 (5), 804-814. doi: 10.1038/s41588-019-0403-1 |
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2019 Journal Article Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomizationEvans, David M., Moen, Gunn-Helen, Hwang, Liang-Dar, Lawlor, Debbie A. and Warrington, Nicole M. (2019). Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization. International Journal of Epidemiology, 48 (3), 861-875. doi: 10.1093/ije/dyz019 |
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2019 Journal Article Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysisHartwig, Fernando Pires, Davies, Neil Martin, Horta, Bernardo Lessa, Ahluwalia, Tarunveer S., Bisgaard, Hans, Bønnelykke, Klaus, Caspi, Avshalom, Moffitt, Terrie E., Poulton, Richie, Sajjad, Ayesha, Tiemeier, Henning W., Dalmau-Bueno, Albert, Guxens, Mònica, Bustamante, Mariona, Santa-Marina, Loreto, Parker, Nadine, Paus, Tomáš, Pausova, Zdenka, Lauritzen, Lotte, Schnurr, Theresia M., Michaelsen, Kim F., Hansen, Torben, Oddy, Wendy, Pennell, Craig E., Warrington, Nicole M., Davey Smith, George and Victora, Cesar Gomes (2019). Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis. International Journal of Epidemiology, 48 (1), 45-57. doi: 10.1093/ije/dyy273 |
