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2024 Journal Article No Evidence of Interaction Between FADS2 Genotype and Breastfeeding on Cognitive or Other Traits in the UK BiobankCentorame, Giulio, Warrington, Nicole M., Hemani, Gibran, Wang, Geng, Davey Smith, George and Evans, David M. (2024). No Evidence of Interaction Between FADS2 Genotype and Breastfeeding on Cognitive or Other Traits in the UK Biobank. Behavior Genetics l1855, 1-17. doi: 10.1007/s10519-024-10210-0 |
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2024 Journal Article A framework for conducting GWAS using repeated measures data with an application to childhood BMIBurrows, Kimberley, Heiskala, Anni, Bradfield, Jonathan P., Balkhiyarova, Zhanna, Ning, Lijiao, Boissel, Mathilde, Chan, Yee-Ming, Froguel, Philippe, Bonnefond, Amelie, Hakonarson, Hakon, Alves, Alexessander Couto, Lawlor, Deborah A., Kaakinen, Marika, Järvelin, Marjo-Riitta, Grant, Struan F. A., Tilling, Kate, Prokopenko, Inga, Sebert, Sylvain, Canouil, Mickaël and Warrington, Nicole M. (2024). A framework for conducting GWAS using repeated measures data with an application to childhood BMI. Nature Communications, 15 (1) 10067, 1-18. doi: 10.1038/s41467-024-53687-3 |
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2024 Journal Article DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traitsHwang, Liang-Dar, Cuellar-Partida, Gabriel, Yengo, Loic, Zeng, Jian, Toivonen, Jarkko, Arvas, Mikko, Beaumont, Robin N., Freathy, Rachel M., Moen, Gunn-Helen, Warrington, Nicole M. and Evans, David M. (2024). DINGO: increasing the power of locus discovery in maternal and fetal genome-wide association studies of perinatal traits. Nature Communications, 15 (1) 9255, 1-14. doi: 10.1038/s41467-024-53495-9 |
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2024 Journal Article Is lower birthweight truly causal for increased cardiovascular risk?Warrington, Nicole M, Wang, Geng and Bond, Tom A (2024). Is lower birthweight truly causal for increased cardiovascular risk?. European Heart Journal, 45 (45), 4865-4866. doi: 10.1093/eurheartj/ehae509 |
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2024 Journal Article The prospective association between early life growth and breast density in young adult womenLloyd, Rachel, Pirikahu, Sarah, Walter, Jane, Cadby, Gemma, Warrington, Nicole, Perera, Dilukshi, Hickey, Martha, Saunders, Christobel, Hackmann, Michael, Sampson, David D., Shepherd, John, Lilge, Lothar and Stone, Jennifer (2024). The prospective association between early life growth and breast density in young adult women. Cancers, 16 (13) 2418, 1-16. doi: 10.3390/cancers16132418 |
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2024 Journal Article A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humansMoksnes, Marta R., Hansen, Ailin F., Wolford, Brooke N., Thomas, Laurent F., Rasheed, Humaira, Simić, Anica, Bhatta, Laxmi, Brantsæter, Anne Lise, Surakka, Ida, Zhou, Wei, Magnus, Per, Njølstad, Pål R., Andreassen, Ole A., Syversen, Tore, Zheng, Jie, Fritsche, Lars G., Evans, David M., Warrington, Nicole M., Nøst, Therese H., Åsvold, Bjørn Olav, Flaten, Trond Peder, Willer, Cristen J., Hveem, Kristian and Brumpton, Ben M. (2024). A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans. Communications Biology, 7 (1) 432, 432. doi: 10.1038/s42003-024-06101-z |
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2024 Journal Article Meta-regression of genome-wide association studies to estimate age-varying genetic effectsPagoni, Panagiota, Higgins, Julian P. T., Lawlor, Deborah A., Stergiakouli, Evie, Warrington, Nicole M., Morris, Tim T. and Tilling, Kate (2024). Meta-regression of genome-wide association studies to estimate age-varying genetic effects. European Journal of Epidemiology, 39 (3), 257-270. doi: 10.1007/s10654-023-01086-1 |
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2024 Journal Article Maternal plasma cortisol’s effect on offspring birth weight: a Mendelian Randomisation studyThompson, W. D., Reynolds, R. M., Beaumont, R. N., Warrington, N. M., Tyrrell, J., Wood, A. R., Evans, D. M., McDonald, T. J., Hattersley, A. H., Freathy, R. M., Lawlor, D. A. and Borges, M. C. (2024). Maternal plasma cortisol’s effect on offspring birth weight: a Mendelian Randomisation study. BMC Pregnancy and Childbirth, 24 (1) 65, 1-11. doi: 10.1186/s12884-024-06250-3 |
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2024 Journal Article Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature reviewPower, Grace M., Sanderson, Eleanor, Pagoni, Panagiota, Fraser, Abigail, Morris, Tim, Prince, Claire, Frayling, Timothy M., Heron, Jon, Richardson, Tom G., Richmond, Rebecca, Tyrrell, Jessica, Warrington, Nicole, Davey Smith, George, Howe, Laura D. and Tilling, Kate M. (2024). Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review. European Journal of Epidemiology, 39 (5), 501-520. doi: 10.1007/s10654-023-01032-1 |
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2023 Journal Article Partitioning genetic effects on birthweight at classical human leukocyte antigen loci into maternal and fetal components, using structural equation modellingWang, Geng, Warrington, Nicole M. and Evans, David M. (2023). Partitioning genetic effects on birthweight at classical human leukocyte antigen loci into maternal and fetal components, using structural equation modelling. International Journal of Epidemiology, 53 (1) dyad142, 1-9. doi: 10.1093/ije/dyad142 |
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2023 Journal Article Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation studyZhao, Jian, Stewart, Isobel D., Baird, Denis, Mason, Dan, Wright, John, Zheng, Jie, Gaunt, Tom R., Evans, David M., Freathy, Rachel M., Langenberg, Claudia, Warrington, Nicole M., Lawlor, Deborah A. and Borges, Maria Carolina (2023). Causal effects of maternal circulating amino acids on offspring birthweight: a Mendelian randomisation study. eBioMedicine, 88 104441, 1-14. doi: 10.1016/j.ebiom.2023.104441 |
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2023 Journal Article Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization studyDecina, Caitlin S., Hopkins, Rhian, Bowden, Jack, Shields, Beverly M., Lawlor, Deborah A., Warrington, Nicole M., Evans, David M., Freathy, Rachel M. and Beaumont, Robin N. (2023). Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study. International Journal of Epidemiology, 52 (1), 178-189. doi: 10.1093/ije/dyac186 |
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2022 Journal Article Using genomic structural equation modeling to partition the genetic covariance between birthweight and cardiometabolic risk factors into maternal and offspring components in the Norwegian HUNT studyMoen, Gunn-Helen, Nivard, Michel, Bhatta, Laxmi, Warrington, Nicole M., Willer, Cristen, Åsvold, Bjørn Olav, Brumpton, Ben and Evans, David M. (2022). Using genomic structural equation modeling to partition the genetic covariance between birthweight and cardiometabolic risk factors into maternal and offspring components in the Norwegian HUNT study. Behavior Genetics, 53 (1), 1-13. doi: 10.1007/s10519-022-10116-9 |
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2022 Journal Article Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer riskD’Urso, Shannon, Arumugam, Pooja, Weider, Therese, Hwang, Liang-Dar, Bond, Tom A., Kemp, John P., Warrington, Nicole M., Evans, David M., O’Mara, Tracy A. and Moen, Gunn-Helen (2022). Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk. BMC Medicine, 20 (1) 419, 1-17. doi: 10.1186/s12916-022-02585-w |
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2022 Journal Article Birth weight and cardiometabolic risk factors: a discordant twin study in the UK BiobankWang, Geng, Bond, Tom A., Warrington, Nicole M. and Evans, David M. (2022). Birth weight and cardiometabolic risk factors: a discordant twin study in the UK Biobank. Journal of Developmental Origins of Health and Disease, 14 (2) PII S2040174422000538, 1-7. doi: 10.1017/s2040174422000538 |
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2022 Journal Article Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birthBrito Nunes, Caroline, Huang, Peiyuan, Wang, Geng, Lundberg, Mischa, D’Urso, Shannon, Wootton, Robyn E., Borges, Maria Carolina, Lawlor, Deborah A., Warrington, Nicole M., Evans, David M., Hwang, Liang-Dar and Moen, Gunn-Helen (2022). Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth. International Journal of Epidemiology, 52 (1), 1-13. doi: 10.1093/ije/dyac121 |
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2022 Journal Article Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic healthWang, Geng, Bhatta, Laxmi, Moen, Gunn-Helen, Hwang, Liang-Dar, Kemp, John P., Bond, Tom A., Åsvold, Bjørn Olav, Brumpton, Ben, Evans, David M. and Warrington, Nicole M. (2022). Investigating a potential causal relationship between maternal blood pressure during pregnancy and future offspring cardiometabolic health. Hypertension, 79 (1), 170-177. doi: 10.1161/hypertensionaha.121.17701 |
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2021 Journal Article Fetal alleles predisposing to metabolically favourable adiposity are associated with higher birth weightThompson, William D., Beaumont, Robin N., Kuang, Alan, Warrington, Nicole M., Ji, Yingjie, Tyrrell, Jess, Wood, Andrew R., Scholtens, Denise, Knight, Bridget A., Evans, David M., Lowe, Bill L., Santorelli, Gillian, Azad, Raq, Mason, Dan, Hattersley, Andrew T., Frayling, Timothy M., Yaghootkar, Hanieh, Borges, Maria-Carolina, Lawlor, Deborah A. and Freathy, Rachel M. (2021). Fetal alleles predisposing to metabolically favourable adiposity are associated with higher birth weight. Human Molecular Genetics, 31 (11), 1762-1775. doi: 10.1093/hmg/ddab356 |
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2021 Journal Article Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profileThompson, William D., Beaumont, Robin N., Kuang, Alan, Warrington, Nicole M., Ji, Yingjie, Tyrrell, Jessica, Wood, Andrew R., Scholtens, Denise M., Knight, Bridget A., Evans, David M., Lowe, William L., Santorelli, Gillian, Azad, Rafaq, Mason, Dan, Hattersley, Andrew T., Frayling, Timothy M., Yaghootkar, Hanieh, Borges, Maria Carolina, Lawlor, Deborah A. and Freathy, Rachel M. (2021). Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile. Diabetologia, 64 (12), 2790-2802. doi: 10.1007/s00125-021-05570-9 |
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2021 Journal Article Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results dataWarrington, Nicole M., Hwang, Liang-Dar, Nivard, Michel G. and Evans, David M. (2021). Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data. Nature Communications, 12 (1) 5420, 1-12. doi: 10.1038/s41467-021-25723-z |
