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2014 Journal Article Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studiesWarrington, Nicole M., Tilling, Kate, Howe, Laura D., Paternoster, Lavinia, Pennell, Craig E., Wu, Yan Yan and Briollais, Laurent (2014). Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studies. Statistical Applications in Genetics and Molecular Biology, 13 (5), 567-587. doi: 10.1515/sagmb-2013-0066 |
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2014 Journal Article Common variation near ROBO2 is associated with expressive vocabulary in infancySt Pourcain, Beate, Cents, Rolieke A. M., Whitehouse, Andrew J. O., Haworth, Claire M. A., Davis, Oliver S. P., O'Reilly, Paul F., Roulstone, Susan, Wren, Yvonne, Ang, Qi W., Velders, Fleur P., Evans, David M., Kemp, John P., Warrington, Nicole M., Miller, Laura, Timpson, Nicholas J., Ring, Susan M., Verhulst, Frank C., Hofman, Albert, Rivadeneira, Fernando, Meaburn, Emma L., Price, Thomas S., Dale, Philip S., Pillas, Demetris, Yliherva, Anneli, Rodriguez, Alina, Golding, Jean, Jaddoe, Vincent W. V., Jarvelin, Marjo-Riitta, Plomin, Robert ... Smith, George Davey (2014). Common variation near ROBO2 is associated with expressive vocabulary in infancy. Nature Communications, 5 (1) A4831, 1-9. doi: 10.1038/ncomms5831 |
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2014 Journal Article Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male pubertyCousminer, Diana L., Stergiakouli, Evangelia, Berry, Diane J., Ang, Wei, Groen-Blokhuis, Maria M., Koerner, Antje, Siitonen, Niina, Ntalla, Ioanna, Marinelli, Marcella, Perry, John R. B., Kettunen, Johannes, Jansen, Rick, Surakka, Ida, Timpson, Nicholas J., Ring, Susan, Mcmahon, George, Power, Chris, Wang, Carol, Kahonen, Mika, Viikari, Jorma, Lehtimaki, Terho, Middeldorp, Christel M., Pol, Hilleke E. Hulshoff, Neef, Madlen, Weise, Sebastian, Pahkala, Katja, Niinikoski, Harri, Zeggini, Eleftheria, Panoutsopoulou, Kalliope ... Warrington, Nicole M. (2014). Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics, 23 (16) ddu150, 4452-4464. doi: 10.1093/hmg/ddu150 |
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2014 Journal Article Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainmentKemp, John P., Medina-Gomez, Carolina, Estrada, Karol, St Pourcain, Beate, Heppe, Denise H. M., Warrington, Nicole M., Oei, Ling, Ring, Susan M., Kruithof, Claudia J., Timpson, Nicholas J., Wolber, Lisa E., Reppe, Sjur, Gautvik, Kaare, Grundberg, Elin, Ge, Bing, van der Eerden, Bram, van de Peppel, Jeroen, Hibbs, Matthew A., Ackert-Bicknell, Cheryl L., Choi, Kwangbom, Koller, Daniel L., Econs, Michael J., Williams, Frances M. K., Foroud, Tatiana, Carola Zillikens, M., Ohlsson, Claes, Hofman, Albert, Uitterlinden, Andre G., Davey Smith, George ... Evans, David M. (2014). Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. PLoS Genetics, 10 (6) e1004423, 1-18. doi: 10.1371/journal.pgen.1004423 |
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2014 Conference Publication Bivariate genetic association analysis of pediatric total-body DXA parameters identifies two novel genetic variants that jointly influence bone mineral content and bone areaKemp, John P., Medina-Gomez, Carolina, Warrington, Nicole M., Heppe, Denise H. M., Timpson, Nicholas J., Oei, Ling, St Pourcain, Beate, Kruithof, Claudia J., Zillikens, M. Carola, Hofman, Albert, Uitterlinden, Andre G., Smith, George Davey, Jaddoe, Vincent W. V., Tobias, Jonathan H., Rivadeneira, Fernando and Evans, David M. (2014). Bivariate genetic association analysis of pediatric total-body DXA parameters identifies two novel genetic variants that jointly influence bone mineral content and bone area. Annual Meeting of the American Society for Bone and Mineral Research, Houston, Texas, United States, 12-15 September 2014. Hoboken, NJ, United States: Wiley-Blackwell Publishing. |
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2013 Journal Article Association of a body mass index genetic risk score with growth throughout childhood and adolescenceWarrington, Nicole M., Howe, Laura D., Wu, Yan Yan, Timpson, Nicholas J., Tilling, Kate, Pennell, Craig E., Newnham, John, Davey-Smith, George, Palmer, Lyle J., Beilin, Lawrence J., Lye, Stephen J., Lawlor, Debbie A. and Briollais, L. (2013). Association of a body mass index genetic risk score with growth throughout childhood and adolescence. PLoS One, 8 (11) e79547, e79547. doi: 10.1371/journal.pone.0079547 |
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2013 Journal Article Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitizationBønnelykke, Klaus, Matheson, Melanie C., Pers, Tune H., Granell, Raquel, Strachan, David P., Alves, Alexessander Couto, Linneberg, Allan, Curtin, John A., Warrington, Nicole M., Standl, Marie, Kerkhof, Marjan, Jonsdottir, Ingileif, Bukvic, Blazenka K., Kaakinen, Marika, Sleimann, Patrick, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Schramm, Katharina, Baltic, Svetlana, Kreiner-Møller, Eskil, Simpson, Angela, St Pourcain, Beate, Coin, Lachlan, Hui, Jennie, Walters, Eugene H., Tiesler, Carla M. T., Duffy, David L., Jones, Graham, Ring, Susan M. ... Brown, Matthew A. (2013). Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nature Genetics, 45 (8), 902-906. doi: 10.1038/ng.2694 |
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2013 Journal Article Association of adiposity genetic variants with menarche timing in 92,105 women of European descentFernández-Rhodes, Lindsay, Demerath, Ellen W., Cousminer, Diana L., Tao, Ran, Dreyfus, Jill G., Esko, Tõnu, Smith, Albert V., Gudnason, Vilmundur, Harris, Tamara B., Launer, Lenore, McArdle, Patrick F., Yerges-Armstrong, Laura M., Elks, Cathy E., Strachan, David P., Kutalik, Zoltán, Vollenweider, Peter, Feenstra, Bjarke, Boyd, Heather A., Metspalu, Andres, Mihailov, Evelin, Broer, Linda, Zillikens, M. Carola, Oostra, Ben, van Duijn, Cornelia M., Lunetta, Kathryn L., Perry, John R. B., Murray, Anna, Koller, Daniel L., Lai, Dongbing ... Franceschini, Nora (2013). Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. American Journal of Epidemiology, 178 (3), 451-460. doi: 10.1093/aje/kws473 |
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2013 Journal Article Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposityCousminer D.L., Berry D.J., Timpson N.J., Ang W., Thiering E., Byrne E.M., Rob Taal H., Huikari V., Bradfield J.P., Kerkhof M., Groen-Blokhuis M.M., Kreiner-Moller E., Marinelli M., Holst C., Leinonen J.T., Perry J.R.B., Surakka I., Pietilainen O., Kettunen J., Anttila V., Kaakinen M., Sovio U., Pouta A., Das S., Lagou V., Power C., Prokopenko I., Evans D.M., Kemp J.P. ... Middeldorp, Christel (2013). Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, 22 (13), 2735-2747. doi: 10.1093/hmg/ddt104 |
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2013 Journal Article Corrigendum: Common variants at 12q15 and 12q24 are associated with infant head circumference (vol 44, pg 532, 2012)Taal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Moller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Monica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bonnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., EKim, Cecilia, Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Jaddoe, Vincent W. V. (2013). Corrigendum: Common variants at 12q15 and 12q24 are associated with infant head circumference (vol 44, pg 532, 2012). Nature Genetics, 45 (6), 713-713. doi: 10.1038/ng0613-713a |
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2013 Journal Article A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndromePeters, Kirsten E., Beilby, John, Cadby, Gemma, Warrington, Nicolen M., Bruce, David G., Davis, Wendy A., Davis, Timothy M. E., Wiltshire, Steven, Knuiman, Matthew, McQuillan, Brendan M., Palmer, Lyle J., Thompson, Peter L. and Hung, Joseph (2013). A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndrome. BMC Medical Genetics, 14 (1) 15. doi: 10.1186/1471-2350-14-15 |
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2013 Journal Article Modelling BMI trajectories in children for genetic association studiesWarrington, Nicole M., Wu, Yan Yan, Pennell, Craig E., Marsh, Julie A., Beilin, Lawrence J., Palmer, Lyle J., Lye, Stephen J. and Briollais, Laurent (2013). Modelling BMI trajectories in children for genetic association studies. PLoS One, 8 (1) e53897, e53897. doi: 10.1371/journal.pone.0053897 |
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2013 Journal Article Common variation contributes to the genetic architecture of social communication traitsSt Pourcain, Beate, Whitehouse, Andrew J. O., Ang, Wei Q., Warrington, Nicole M., Glessner, Joseph T., Wang, Kai, Timpson, Nicholas J., Evans, David M., Kemp, John P., Ring,Susan M., McArdle, Wendy L., Golding, Jean, Hakonarson, Hakon, Pennell, Craig E. and Smith, George Davey (2013). Common variation contributes to the genetic architecture of social communication traits. Molecular Autism, 4 (1) 34, 34.1-34.12. doi: 10.1186/2040-2392-4-34 |
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2013 Journal Article New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolismHorikoshi M., Yaghootkar H., Mook-Kanamori D.O., Sovio U., Taal H.R., Hennig B.J., Bradfield J.P., St Pourcain B., Evans D.M., Charoen P., Kaakinen M., Cousminer D.L., Lehtimaki T., Kreiner-Moller E., Warrington N.M., Bustamante M., Feenstra B., Berry D.J., Thiering E., Pfab T., Barton S.J., Shields B.M., Kerkhof M., Van Leeuwen E.M., Fulford A.J., Kutalik Z., Zhao J.H., Den Hoed M., Mahajan A. ... Freathy R.M. (2013). New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics, 45 (1), 76-82. doi: 10.1038/ng.2477 |
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2013 Journal Article Genetic influences on trajectories of systolic blood pressure across childhood and adolescenceHowe, Laura D., Parmar, Priyakumari G., Paternoster, Lavinia, Warrington, Nicole M., Kemp, John P., Briollais, Laurent, Newnham, John P., Timpson, Nicholas J., Smith, George D., Ring, Susan M., Evans, David M., Tilling, Kate, Pennell, Craig E., Beilin, Lawrie J., Palmer, Lyle J. and Lawlor, Debbie A. (2013). Genetic influences on trajectories of systolic blood pressure across childhood and adolescence. Circulation: Cardiovascular Genetics, 6 (6), 608-614. doi: 10.1161/CIRCGENETICS.113.000197 |
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2012 Journal Article Genome-wide meta-analysis of common variant differences between men and womenBoraska, Vesna, Jeroncic, Ana, Colonna, Vincenza, Southam, Lorraine, Nyholt, Dale R., Rayner, Nigel William, Perry, John R. B., Toniolo, Daniela, Albrecht, Eva, Ang, Wei, Bandinelli, Stefania, Barbalic, Maja, Barroso, Ines, Beckmann, Jacques S., Biffar, Reiner, Boomsma, Dorret, Campbell, Harry, Corre, Tanguy, Erdmann, Jeanette, Esko, Tonu, Fischer, Krista, Franceschini, Nora, Frayling, Timothy M., Girotto, Giorgia, Gonzalez, Juan R., Harris, Tamara B., Heath, Andrew C., Heid, Iris M., Hoffmann, Wolfgang ... Zeggini, Eleftheria (2012). Genome-wide meta-analysis of common variant differences between men and women. Human Molecular Genetics, 21 (21) dds304, 4805-4815. doi: 10.1093/hmg/dds304 |
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2012 Journal Article Genome-Wide Association Study to Identify the Genetic Determinants of Otitis Media Susceptibility in ChildhoodRye, Marie S., Warrington, Nicole M., Scaman, Elizabeth S. H., Vijayasekaran, Shyan, Coates, Harvey L., Anderson, Denise, Pennell, Craig E., Blackwell, Jenefer M. and Jamieson, Sarra E. (2012). Genome-Wide Association Study to Identify the Genetic Determinants of Otitis Media Susceptibility in Childhood. PLoS One, 7 (10) e48215, e48215.1-e48215.12. doi: 10.1371/journal.pone.0048215 |
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2012 Journal Article A genome-wide association meta-analysis identifies new childhood obesity lociBradfield, Jonathan P., Taal, H. Rob, Timpson, Nicholas J., Scherag, André, Lecoeur, Cecile, Warrington, Nicole M., Hypponen, Elina, Holst, Claus, Valcarcel, Beatriz, Thiering, Elisabeth, Salem, Rany M., Schumacher, Fredrick R., Cousminer, Diana L., Sleiman, Patrick M. A., Zhao, Jianhua, Berkowitz, Robert I., Vimaleswaran, Karani S., Jarick, Ivonne, Pennell, Craig E., Evans, David M., St Pourcain, Beate, Berry, Diane J., Mook-Kanamori, Dennis O., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., van Duijn, Cornelia M., van der Valk, Ralf J. P., de Jongste, Johan C. ... Grant, Struan F. A. (2012). A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genetics, 44 (5), 526-531. doi: 10.1038/ng.2247 |
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2012 Journal Article Associations between anxious-depressed symptoms and cardiovascular risk factors in a longitudinal childhood studyLouise, Sandra, Warrington, Nicole M., McCaskie, Pamela A., Oddy, Wendy H., Zubrick, Stephen R., Hands, Beth, Mori, Trevor A., Briollais, Laurent, Silburn, Sven, Palmer, Lyle J., Mattes, Eugen and Beilin, Lawrence J. (2012). Associations between anxious-depressed symptoms and cardiovascular risk factors in a longitudinal childhood study. Preventive Medicine, 54 (5), 345-350. doi: 10.1016/j.ypmed.2012.03.004 |
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2012 Journal Article Common variants at 12q15 and 12q24 are associated with infant head circumferenceTaal, H. Rob, St Pourcain, Beate, Thiering, Elisabeth, Das, Shikta, Mook-Kanamori, Dennis O., Warrington, Nicole M., Kaakinen, Marika, Kreiner-Møller, Eskil, Bradfield, Jonathan P., Freathy, Rachel M., Geller, Frank, Guxens, Mònica, Cousminer, Diana L., Kerkhof, Marjan, Timpson, Nicholas J., Ikram, M. Arfan, Beilin, Lawrence J., Bønnelykke, Klaus, Buxton, Jessica L., Charoen, Pimphen, Chawes, Bo Lund Krogsgaard, Eriksson, Johan, Evans, David M., Hofman, Albert, Kemp, John P., Kim, Cecilia E., Klopp, Norman, Lahti, Jari, Lye, Stephen J. ... Middeldorp, Christel (2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, 44 (5), 532-538. doi: 10.1038/ng.2238 |
