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2017

Conference Publication

Performing Mendelian randomization using structural equation models

Evans, David and Warrington, Nicole (2017). Performing Mendelian randomization using structural equation models. 47th Annual Meeting of the Behavior-Genetics-Association (BGA), Oslo Norway, 28 June - 1 July 2017. New York NY United States: Springer.

Performing Mendelian randomization using structural equation models

2016

Conference Publication

Genome-wide association study of 6,939 individuals identifies five novel loci and suggests that prenatal exposure to testosterone is not a major determinant of individual differences in 2D:4D finger ratio

Warrington, Nicole, Hemani, Gibran, Hysi, Pirro, Mangino, Massimo, McMahon, George, Hickey, Martha, Wolke, Dieter, Montgomery, Grant, Pennell, Craig, Spector, Tim, Martin, Nicholas, Medland, Sarah and Evans, David (2016). Genome-wide association study of 6,939 individuals identifies five novel loci and suggests that prenatal exposure to testosterone is not a major determinant of individual differences in 2D:4D finger ratio. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

Genome-wide association study of 6,939 individuals identifies five novel loci and suggests that prenatal exposure to testosterone is not a major determinant of individual differences in 2D:4D finger ratio

2016

Conference Publication

Locus Discovery in Genome-wide Association Studies using Bivariate Analysis

Warrington, Nicole M. and Evans, David M. (2016). Locus Discovery in Genome-wide Association Studies using Bivariate Analysis. Annual Meeting of the International-Genetic-Epidemiology-Society, Toronto Canada, Oct 24-26, 2016. HOBOKEN: WILEY-BLACKWELL.

Locus Discovery in Genome-wide Association Studies using Bivariate Analysis

2016

Conference Publication

LD hub and MR-base: online platforms for preforming LD score regression and Mendelian randomization analysis using GWAS summary data

Zheng, Jie, Haycock, Philip, Hemani, Gibran, Elsworth, Benjamin, Shihab, Hashem, Laurin, Charles, Erzurumluoglu, Mesut, Howe, Laurence, Wade, Kaitlin, Warrington, Nicole, Finucane, Hilary, Price, Alkes, Anttila, Verneri, Paternoster, Lavinia, Martin, Richard, Relton, Caroline, Gaunt, Tom, Smith, George Davey, Neale, Benjamin and Evans, David (2016). LD hub and MR-base: online platforms for preforming LD score regression and Mendelian randomization analysis using GWAS summary data. 46th Annual Meeting of the Behavior-Genetics-Association, Brisbane Australia, Jun 20-23, 2016. NEW YORK: SPRINGER.

LD hub and MR-base: online platforms for preforming LD score regression and Mendelian randomization analysis using GWAS summary data

2016

Journal Article

Genome-wide associations for birth weight and correlations with adult disease

Horikoshi, Momoko, Beaumont, Robin N., Day, Felix R., Warrington, Nicole M., Kooijman, Marjolein N., Fernandez-Tajes, Juan, Feenstra, Bjarke, van Zuydam, Natalie R., Gaulton, Kyle J., Grarup, Niels, Bradfield, Jonathan P., Strachan, David P., Li-Gao, Ruifang, Ahluwalia, Tarunveer S., Kreiner, Eskil, Rueedi, Rico, Lyytikainen, Leo-Pekka, Cousminer, Diana L., Wu, Ying, Thiering, Elisabeth, Wang, Carol A., Have, Christian T., Hottenga, Jouke-Jan, Vilor-Tejedor, Natalia, Joshi, Peter K., Boh, Eileen Tai Hui, Ntalla, Ioanna, Pitkanen, Niina, Mahajan, Anubha ... Freathy, Rachel M. (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 538 (7624), 248-252. doi: 10.1038/nature19806

Genome-wide associations for birth weight and correlations with adult disease

2015

Conference Publication

Shared genetic origins of allergy and autoimmune diseases

Waage, J. E., Kreiner-Moller, E., Standl, M., Brix, S., Pers, T. H., Alves, A. C., Warrington, N. M., Tiesler, C. M., Fuertes, E., Franke, L., Hirschhorn, J. N., James, A., Simpson, A., Tung, J. Y., Koppelman, G. H., Postma, D. S., Pennel, C. E., Jarvelin, M-R, Custovic, A., Timpson, N., Ferreira, M. A., Strachan, D. P., Hinds, D., Bisgaard, H. and Bonnelykke, K. (2015). Shared genetic origins of allergy and autoimmune diseases. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology, Barcelona Spain, Jun 06-10, 2015. HOBOKEN: WILEY-BLACKWELL.

Shared genetic origins of allergy and autoimmune diseases

2015

Journal Article

Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence

Warrington, Nicole M., Kemp, John P., Tilling, Kate, Tobias, Jonathan H. and Evans, David M. (2015). Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence. Human Molecular Genetics, 24 (14) ddv143, 4158-4166. doi: 10.1093/hmg/ddv143

Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence

2015

Journal Article

A genome-wide association study of body mass index across early life and childhood

Warrington, Nicole M., Howe, Laura D., Paternoster, Lavinia, Kaakinen, Marika, Herrala, Sauli, Huikari, Ville, Wu, Yan Yan, Kemp, John P., Timpson, Nicholas J., Pourcain, Beate St, Smith, George Davey, Tilling, Kate, Jarvelin, Marjo-Riitta, Pennell, Craig E., Evans, David M., Lawlor, Debbie A., Briollais, Laurent and Palmer, Lyle J. (2015). A genome-wide association study of body mass index across early life and childhood. International Journal of Epidemiology, 44 (2) dyv077, 700-712. doi: 10.1093/ije/dyv077

A genome-wide association study of body mass index across early life and childhood

2015

Journal Article

Genome-wide association study of blood lead shows multiple associations near ALAD

Warrington, Nicole M., Zhu, Gu, Dy, Veronica, Heath, Andrew C., Madden, Pamela A. F., Hemani, Gibran, Kemp, John P., Mcmahon, George, St Pourcain, Beate, Timpson, Nicholas J., Taylor, Caroline M., Golding, Jean, Lawlor, Debbie A., Steer, Colin, Montgomery, Grant W., Martin, Nicholas G., Smith, George Davey, Evans, David M. and Whitfield, John B. (2015). Genome-wide association study of blood lead shows multiple associations near ALAD. Human Molecular Genetics, 24 (13) ddv112, 3871-3879. doi: 10.1093/hmg/ddv112

Genome-wide association study of blood lead shows multiple associations near ALAD

2015

Journal Article

Brief report: intestinal dysbiosis in ankylosing spondylitis

Costello, Mary-Ellen, Ciccia, Francesco, Willner, Dana, Warrington, Nicole, Robinson, Philip C., Gardiner, Brooke, Marshall, Mhairi, Kenna, Tony J., Triolo. Giovanni and Brown, Matthew A. (2015). Brief report: intestinal dysbiosis in ankylosing spondylitis. Arthritis and Rheumatology, 67 (3), 686-691. doi: 10.1002/art.38967

Brief report: intestinal dysbiosis in ankylosing spondylitis

2015

Journal Article

A novel common variant in DCST2 is associated with length in early life and height in adulthood

van der Valk, Ralf J. P., Kreiner-Moller, Eskil, Kooijman, Marjolein N., Guxens, Monica, Stergiakouli, Evangelia, Saaf, Annika, Bradfield, Jonathan P., Geller, Frank, Hayes, M. Geoffrey, Cousminer, Diana L., Koerner, Antje, Thiering, Elisabeth, Curtin, John A., Myhre, Ronny, Huikari, Ville, Joro, Raimo, Kerkhof, Marjan, Warrington, Nicole M., Pitkanen, Niina, Ntalla, Ioanna, Horikoshi, Momoko, Veijola, Riitta, Freathy, Rachel M., Teo, Yik-Ying, Barton, Sheila J., Evans, David M., Kemp, John P., St Pourcain, Beate, Ring, Susan M. ... for the Early Growth Genetics (EGG) Consortium (2015). A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics, 24 (4) ddu510, 1155-1168. doi: 10.1093/hmg/ddu510

A novel common variant in DCST2 is associated with length in early life and height in adulthood

2015

Conference Publication

Large scale genome-wide association study for birth weight identifies 13 novel loci and reveals genetic links with a variety of adult metabolic and anthropometric traits

Horikoahi, Momoko, Day, Felix R., Perry, John R. B., Hottenga, Jouke-Jan, Li-Gao, Ruifang, Beaumont, Robin, Warrington, Nicole M. and Timpson, Nicholas J. (2015). Large scale genome-wide association study for birth weight identifies 13 novel loci and reveals genetic links with a variety of adult metabolic and anthropometric traits. Annual Meeting of the International-Genetic-Epidemiology-Society (IGES), Baltimore, Md, United States, Oct 04-06 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/gepi.21916

Large scale genome-wide association study for birth weight identifies 13 novel loci and reveals genetic links with a variety of adult metabolic and anthropometric traits

2014

Journal Article

Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studies

Warrington, Nicole M., Tilling, Kate, Howe, Laura D., Paternoster, Lavinia, Pennell, Craig E., Wu, Yan Yan and Briollais, Laurent (2014). Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studies. Statistical Applications in Genetics and Molecular Biology, 13 (5), 567-587. doi: 10.1515/sagmb-2013-0066

Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studies

2014

Journal Article

Common variation near ROBO2 is associated with expressive vocabulary in infancy

St Pourcain, Beate, Cents, Rolieke A. M., Whitehouse, Andrew J. O., Haworth, Claire M. A., Davis, Oliver S. P., O'Reilly, Paul F., Roulstone, Susan, Wren, Yvonne, Ang, Qi W., Velders, Fleur P., Evans, David M., Kemp, John P., Warrington, Nicole M., Miller, Laura, Timpson, Nicholas J., Ring, Susan M., Verhulst, Frank C., Hofman, Albert, Rivadeneira, Fernando, Meaburn, Emma L., Price, Thomas S., Dale, Philip S., Pillas, Demetris, Yliherva, Anneli, Rodriguez, Alina, Golding, Jean, Jaddoe, Vincent W. V., Jarvelin, Marjo-Riitta, Plomin, Robert ... Smith, George Davey (2014). Common variation near ROBO2 is associated with expressive vocabulary in infancy. Nature Communications, 5 (1) A4831, 1-9. doi: 10.1038/ncomms5831

Common variation near ROBO2 is associated with expressive vocabulary in infancy

2014

Journal Article

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

Cousminer, Diana L., Stergiakouli, Evangelia, Berry, Diane J., Ang, Wei, Groen-Blokhuis, Maria M., Koerner, Antje, Siitonen, Niina, Ntalla, Ioanna, Marinelli, Marcella, Perry, John R. B., Kettunen, Johannes, Jansen, Rick, Surakka, Ida, Timpson, Nicholas J., Ring, Susan, Mcmahon, George, Power, Chris, Wang, Carol, Kahonen, Mika, Viikari, Jorma, Lehtimaki, Terho, Middeldorp, Christel M., Pol, Hilleke E. Hulshoff, Neef, Madlen, Weise, Sebastian, Pahkala, Katja, Niinikoski, Harri, Zeggini, Eleftheria, Panoutsopoulou, Kalliope ... Warrington, Nicole M. (2014). Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics, 23 (16) ddu150, 4452-4464. doi: 10.1093/hmg/ddu150

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

2014

Journal Article

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment

Kemp, John P., Medina-Gomez, Carolina, Estrada, Karol, St Pourcain, Beate, Heppe, Denise H. M., Warrington, Nicole M., Oei, Ling, Ring, Susan M., Kruithof, Claudia J., Timpson, Nicholas J., Wolber, Lisa E., Reppe, Sjur, Gautvik, Kaare, Grundberg, Elin, Ge, Bing, van der Eerden, Bram, van de Peppel, Jeroen, Hibbs, Matthew A., Ackert-Bicknell, Cheryl L., Choi, Kwangbom, Koller, Daniel L., Econs, Michael J., Williams, Frances M. K., Foroud, Tatiana, Carola Zillikens, M., Ohlsson, Claes, Hofman, Albert, Uitterlinden, Andre G., Davey Smith, George ... Evans, David M. (2014). Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. PLoS Genetics, 10 (6) e1004423, 1-18. doi: 10.1371/journal.pgen.1004423

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment

2014

Conference Publication

Bivariate genetic association analysis of pediatric total-body DXA parameters identifies two novel genetic variants that jointly influence bone mineral content and bone area

Kemp, John P., Medina-Gomez, Carolina, Warrington, Nicole M., Heppe, Denise H. M., Timpson, Nicholas J., Oei, Ling, St Pourcain, Beate, Kruithof, Claudia J., Zillikens, M. Carola, Hofman, Albert, Uitterlinden, Andre G., Smith, George Davey, Jaddoe, Vincent W. V., Tobias, Jonathan H., Rivadeneira, Fernando and Evans, David M. (2014). Bivariate genetic association analysis of pediatric total-body DXA parameters identifies two novel genetic variants that jointly influence bone mineral content and bone area. Annual Meeting of the American Society for Bone and Mineral Research, Houston, Texas, United States, 12-15 September 2014. Hoboken, NJ, United States: Wiley-Blackwell Publishing.

Bivariate genetic association analysis of pediatric total-body DXA parameters identifies two novel genetic variants that jointly influence bone mineral content and bone area

2013

Journal Article

Association of a body mass index genetic risk score with growth throughout childhood and adolescence

Warrington, Nicole M., Howe, Laura D., Wu, Yan Yan, Timpson, Nicholas J., Tilling, Kate, Pennell, Craig E., Newnham, John, Davey-Smith, George, Palmer, Lyle J., Beilin, Lawrence J., Lye, Stephen J., Lawlor, Debbie A. and Briollais, L. (2013). Association of a body mass index genetic risk score with growth throughout childhood and adolescence. PLoS One, 8 (11) e79547, e79547. doi: 10.1371/journal.pone.0079547

Association of a body mass index genetic risk score with growth throughout childhood and adolescence

2013

Journal Article

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

Bønnelykke, Klaus, Matheson, Melanie C., Pers, Tune H., Granell, Raquel, Strachan, David P., Alves, Alexessander Couto, Linneberg, Allan, Curtin, John A., Warrington, Nicole M., Standl, Marie, Kerkhof, Marjan, Jonsdottir, Ingileif, Bukvic, Blazenka K., Kaakinen, Marika, Sleimann, Patrick, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Schramm, Katharina, Baltic, Svetlana, Kreiner-Møller, Eskil, Simpson, Angela, St Pourcain, Beate, Coin, Lachlan, Hui, Jennie, Walters, Eugene H., Tiesler, Carla M. T., Duffy, David L., Jones, Graham, Ring, Susan M. ... Brown, Matthew A. (2013). Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nature Genetics, 45 (8), 902-906. doi: 10.1038/ng.2694

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

2013

Journal Article

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

Fernández-Rhodes, Lindsay, Demerath, Ellen W., Cousminer, Diana L., Tao, Ran, Dreyfus, Jill G., Esko, Tõnu, Smith, Albert V., Gudnason, Vilmundur, Harris, Tamara B., Launer, Lenore, McArdle, Patrick F., Yerges-Armstrong, Laura M., Elks, Cathy E., Strachan, David P., Kutalik, Zoltán, Vollenweider, Peter, Feenstra, Bjarke, Boyd, Heather A., Metspalu, Andres, Mihailov, Evelin, Broer, Linda, Zillikens, M. Carola, Oostra, Ben, van Duijn, Cornelia M., Lunetta, Kathryn L., Perry, John R. B., Murray, Anna, Koller, Daniel L., Lai, Dongbing ... Franceschini, Nora (2013). Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. American Journal of Epidemiology, 178 (3), 451-460. doi: 10.1093/aje/kws473

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent