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2012 Journal Article Mapping the stabilome: a novel computational method for classifying metabolic protein stabilityPatrick, Ralph, Cao, Kim-Anh L., Davis, Melissa, Kobe, Bostjan and Bodén, Mikael (2012). Mapping the stabilome: a novel computational method for classifying metabolic protein stability. BMC Systems Biology, 6 (1) 60, 60.1-60.15. doi: 10.1186/1752-0509-6-60 |
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2012 Journal Article The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimerChen, Kai-En, Richards, Ayanthi A., Arrifin, Juliana K., Ross, Ian L., Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer L. (2012). The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer. Acta Crystallographica Section D: Biological Crystallography, 68 (6), 637-648. doi: 10.1107/S0907444912006592 |
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2012 Journal Article Structural basis of high-affinity nuclear localization signal interactions with importin-alphaMarfori, Mary, Lonhienne, Thierry G., Forwood, Jade K. and Kobe, Bostjan (2012). Structural basis of high-affinity nuclear localization signal interactions with importin-alpha. Traffic, 13 (4), 532-548. doi: 10.1111/j.1600-0854.2012.01329.x |
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2012 Journal Article Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencingStark, Mitchell S., Woods, Susan L., Gartside, Michael G., Bonazzi, Vanessa F., Dutton-Regester, Ken, Aoude, Lauren G., Chow, Donald, Sereduk, Chris, Niemi, Natalie M., Tang, Nanyun, Ellis, Jonathan J., Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M., Pollak, Thomas, Youngkin, David, Brooks, Bradford R., Lanagan, Catherine, Schmidt, Christopher W., Kobe, Bostjan, MacKeigan, Jeffrey P., Yin, Hongwei, Brown, Kevin M., Gibbs, Richard, Trent, Jeffrey and Hayward, Nicholas K. (2012). Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nature Genetics, 44 (2), 165-169. doi: 10.1038/ng.1041 |
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2012 Journal Article Conserved anchorless surface proteins as group A streptococcal vaccine candidatesHenningham, Anna, Chiarot, Emiliano, Gillen, Christine M., Cole, Jason N., Rohde, Manfred, Fulde, Marcus, Ramachandran, Vidiya, Cork, Amanda J., Hartas, Jon, Magor, Graham, Djordjevic, Steven P., Cordwell, Stuart J., Kobe, Bostjan, Sriprakash, Kabada S., Nizet, Victor, Chhatwal, G. S., Margarit, Immaculada Y. R., Batzloff, Michael R. and Walker, Mark J. (2012). Conserved anchorless surface proteins as group A streptococcal vaccine candidates. Journal of Molecular Medicine, 90 (10), 1197-1207. doi: 10.1007/s00109-012-0897-9 |
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2012 Journal Article Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan bindingWatterson, Daniel, Kobe, Bostjan and Young, Paul R. (2012). Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding. Journal of General Virology, 93 (1), 72-82. doi: 10.1099/vir.0.037317-0 |
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2011 Journal Article Crystallization and X-ray diffraction analysis of the C-terminal domain of the flax rust effector protein AvrMVe, Thomas, Williams, Simon J., Stamp, Anna, Valkov, Eugene, Dodds, Peter N., Anderson, Peter A. and Kobe, Bostjan (2011). Crystallization and X-ray diffraction analysis of the C-terminal domain of the flax rust effector protein AvrM. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 67 (12), 1603-1607. doi: 10.1107/S1744309111037675 |
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2011 Journal Article Structural mix-n-match reveals molecular secrets of plateletsKobe, Bostjan (2011). Structural mix-n-match reveals molecular secrets of platelets. Blood, 118 (19), 5065-5066. doi: 10.1182/blood-2011-09-379859 |
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2011 Journal Article A molecular mechanism for bacterial susceptibility to zincMcDevitt, Christopher A., Ogunniyi, Abiodun D., Valkov, Eugene, Lawrence, Michael C., Kobe, Bostjan, McEwan, Alastair G. and Paton, James C. (2011). A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens, 7 (11) e1002357, e1002357.1-e1002357.9. doi: 10.1371/journal.ppat.1002357 |
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2011 Journal Article Ligand-induced conformational changes within a hexameric acyl-CoA thioesteraseMarfori, Mary, Kobe, Bostjan and Forwood, Jade K. (2011). Ligand-induced conformational changes within a hexameric acyl-CoA thioesterase. Journal of Biological Chemistry, 286 (41), 35643-35649. doi: 10.1074/jbc.M111.225953 |
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2011 Journal Article Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80Takeda, Agnes A. S., de Barros, Andrea C., Chang, Chiung-Wen, Kobe, Boštjan and Fontes, Marcos R. M. (2011). Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80. Journal of Molecular Biology, 412 (2), 226-234. doi: 10.1016/j.jmb.2011.07.038 |
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2011 Journal Article Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protectionValkov, Eugene, Stamp, Anna, DiMaio, Frank, Baker, David, Verstak, Brett, Roversi, Pietro, Kellie, Stuart, Sweet, Matthew J., Mansell, Ashley, Gay, Nicholas J., Martin, Jennifer L. and Kobe, Bostjan (2011). Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection. Proceedings of the National Academy of Sciences of the United States of America, 108 (36), 14879-14884. doi: 10.1073/pnas.1104780108 |
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2011 Journal Article Molecular basis for specificity of nuclear import and prediction of nuclear localizationMarfori, Mary, Mynott, Andrew, Ellis, Jonathan J., Mehdi, Ahmed M., Saunders, Neil F. W., Curmi, Paul M., Forwood, Jade K., Bodén, Mikael and Kobe, Bostjan (2011). Molecular basis for specificity of nuclear import and prediction of nuclear localization. Biochimica et Biophysica Acta (BBA): Molecular Cell Research, 1813 (9), 1562-1577. doi: 10.1016/j.bbamcr.2010.10.013 |
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2011 Journal Article An autoactive mutant of the M flax rust resistance protein has a preference for binding ATP, whereas wild-type M protein binds ADPWilliams, Simon J., Sornaraj, Pradeep, deCourcy-Ireland, Emma, Menz, R. Ian, Kobe, Bostjan, Ellis, Jeffrey G., Dodds, Peter N. and Anderson, Peter A. (2011). An autoactive mutant of the M flax rust resistance protein has a preference for binding ATP, whereas wild-type M protein binds ADP. Molecular Plant-Microbe Interactions, 24 (8), 897-906. doi: 10.1094/MPMI-03-11-0052 |
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2011 Journal Article Predicting protein kinase specificity : Predikin update and performance in the DREAM4 challengeEllis, Jonathan J. and Kobe, Bostjan (2011). Predicting protein kinase specificity : Predikin update and performance in the DREAM4 challenge. PLoS One, 6 (7) e21169, e21169-1-e21169-7. doi: 10.1371/journal.pone.0021169 |
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2011 Journal Article Proteomic and electron microscopy survey of large assemblies in macrophage cytoplasmMaco, B, Ross, IL, Landsberg, MJ, Mouradov, D, Saunders, NFW, Hankamer, B and Kobe, B (2011). Proteomic and electron microscopy survey of large assemblies in macrophage cytoplasm. Molecular and Cellular Proteomics, 10 (6) M111.008763, M111.008763. doi: 10.1074/mcp.M111.008763 |
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2011 Journal Article Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4Mynott, Andrew V., Harrop, Stephen J., Brown, Louise J., Breit, Samuel N., Kobe, Bostjan and Curmi, Paul M. G. (2011). Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4. The FEBS Journal, 278 (10), 1662-1675. doi: 10.1111/j.1742-4658.2011.08086.x |
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2011 Journal Article A probabilistic model of nuclear import of proteinsMehdi, Ahmed M., Sehgal, Muhammad Shoaib B., Kobe, Bostjan, Bailey, Timothy L. and Boden, Mikael (2011). A probabilistic model of nuclear import of proteins. Bioinformatics, 27 (9) btr121, 1239-1246. doi: 10.1093/bioinformatics/btr121 |
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2011 Journal Article Structural and functional analysis of a plant resistance protein TIR Domain reveals interfaces for self-association, signaling, and autoregulationBemoux, Maud, Ve, Thomas, Williams, Simon, Warren, Christopher, Hatters, Danny, Valkov, Eugene, Zhang, Xiaoxiao, Ellis, Jeffrey G., Kobe, Bostjan and Dodds, Peter N. (2011). Structural and functional analysis of a plant resistance protein TIR Domain reveals interfaces for self-association, signaling, and autoregulation. Cell Host and Microbe, 9 (3), 200-211. doi: 10.1016/j.chom.2011.02.009 |
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2011 Journal Article Crystallization, X-ray diffraction analysis and preliminary structure determination of the TIR domain from the flax resistance protein L6Ve, Thomas, Williams, Simon, Valkov, Eugene, Ellis, Jeffrey G., Dodds, Peter N. and Kobe, Bostjan (2011). Crystallization, X-ray diffraction analysis and preliminary structure determination of the TIR domain from the flax resistance protein L6. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 67 (2), 237-240. doi: 10.1107/S1744309110051006 |
