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2023

Conference Publication

Structural and functional characterisation of plant TIR domains and their role in plant innate immunity

Lim, Bryan Y. J., Sorbello, Mitchell, Ngu, Dalton H. Y., Burdett, Hayden, Maruta, Natsumi and Kobe, Boštjan (2023). Structural and functional characterisation of plant TIR domains and their role in plant innate immunity. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087752

Structural and functional characterisation of plant TIR domains and their role in plant innate immunity

2023

Conference Publication

Development of 3D-ED/MicroED facility at the University of Queensland

Arachchige, K. S. A., Koifman, N., Gu, W., Kobe, B., Clegg, J. K., Xu, H. and Wepf, R. (2023). Development of 3D-ED/MicroED facility at the University of Queensland. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086461

Development of 3D-ED/MicroED facility at the University of Queensland

2023

Conference Publication

Structural and functional analysis of the TIR-domain in Toll-like receptors 7, 8 and 9 signaling and the interactions with adaptor proteins

Qian, Xiaoqi, Nanson, Jeffrey and Kobe, Boštjan (2023). Structural and functional analysis of the TIR-domain in Toll-like receptors 7, 8 and 9 signaling and the interactions with adaptor proteins. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s205327332308662x

Structural and functional analysis of the TIR-domain in Toll-like receptors 7, 8 and 9 signaling and the interactions with adaptor proteins

2023

Conference Publication

Activated bacterial TIR proteins: NADase activity and filamentous assemblies

Li, Sulin, Manik, Mohammad Kawsar, Ve, Thomas, Nanson, Jeffrey D. and Kobe, Bostjan (2023). Activated bacterial TIR proteins: NADase activity and filamentous assemblies. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086904

Activated bacterial TIR proteins: NADase activity and filamentous assemblies

2023

Conference Publication

Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1

Shi, Y., Nanson, J., Gu, W., Masic, V., Mosaiab, T., Landsberg, M., Kobe, B. and Ve, T. (2023). Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087776

Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1

2023

Conference Publication

Characterisation of the solute-binding protein ModA from Pseudomonas aeruginosa and its role in molybdenum homeostasis

Ngu, Dalton H. Y., Maunders, Eve. A., Lim, Bryan Y. J., Luo, Zhenyao, McDevitt, Christopher A. and Kobe, Boštjan (2023). Characterisation of the solute-binding protein ModA from Pseudomonas aeruginosa and its role in molybdenum homeostasis. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323089477

Characterisation of the solute-binding protein ModA from Pseudomonas aeruginosa and its role in molybdenum homeostasis

2023

Conference Publication

TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathways

Nanson, J. D., Muusse, T. W., Li, Y., Pan, M., Landsberg, M. J., Vajjhala, P. R., Ve, T., Stacey, K. J. and Kobe, B. (2023). TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathways. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086631

TLR4 TIR domain higher-order assemblies reveal the structural basis of adaptor recruitment in Toll-like receptor signaling pathways

2023

Conference Publication

Structural and functional characterization of interleukin-1 receptor 8

Alenzi, Athyah, Nimma, Surekha and Kobe, Bostjan (2023). Structural and functional characterization of interleukin-1 receptor 8. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086667

Structural and functional characterization of interleukin-1 receptor 8

2023

Conference Publication

Structural and functional characterisation of plant innate immune receptors

Maruta, Natsumi, Burdett, Hayden, Sorbello, Mitchell, Lim, Bryan Ying Jie, Ngu, Dalton and Kobe, Bostjan (2023). Structural and functional characterisation of plant innate immune receptors. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087764

Structural and functional characterisation of plant innate immune receptors

2023

Conference Publication

Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology

Kobe, Bostjan, Nanson, Jeffrey D., Manik, Mohammad K., Li, Sulin, Gu, Weixi, Pan, Mengqi, Li, Yan, Muusse, Timothy W., Vajjhala, Parimala R, Stacey, Katryn J., Holmes, Susannah, Darmanin, Connie, Clabbers, Max T. B., Xu, Hongyi, Shi, Yun and Ve, Thomas (2023). Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323093658

Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology

2023

Conference Publication

Characterisation of Axundead, a novel downstream regulator of Wallerian degeneration

McGuinness, Helen Ying, Rosell, Arnau Llobert, Gu, Weixi, Nanson, Jeffrey, Ve, Thomas and Kobe, Bostjan (2023). Characterisation of Axundead, a novel downstream regulator of Wallerian degeneration. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323087661

Characterisation of Axundead, a novel downstream regulator of Wallerian degeneration

2023

Conference Publication

Structure determination of TLR2 TIR domain induced MyD88 TIR domain higher-order assembly revealed by microcrystal electron diffraction (microED)

Li, Y., Nanson, J. D., Pacoste, L. C., Xu, H. and Kobe, B. (2023). Structure determination of TLR2 TIR domain induced MyD88 TIR domain higher-order assembly revealed by microcrystal electron diffraction (microED). XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323093993

Structure determination of TLR2 TIR domain induced MyD88 TIR domain higher-order assembly revealed by microcrystal electron diffraction (microED)

2023

Conference Publication

Allosteric regulation of SARM1, the executioner of axon degeneration

Gu, W., Luo, Z., Nanson, J. D., Ve, T. and Kobe, B. (2023). Allosteric regulation of SARM1, the executioner of axon degeneration. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323089398

Allosteric regulation of SARM1, the executioner of axon degeneration

2023

Conference Publication

Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers

Kwah, Kayden, Gu, Weixi, Arachchige, Kasun S. A., He, Yaowu, Landsberg, Michael, Kobe, Bostjan and Hooper, John (2023). Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323084449

Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers

2022

Conference Publication

Structural basis of TIR-domain assembly formation in TRAM- and TRIF- dependent TLR signalling

Pan, M., Hedger, A., Nanson, J., Pospich, S., Ve, T. V. E. A., Raunser, S., Landsberg, M. and Kobe, B. (2022). Structural basis of TIR-domain assembly formation in TRAM- and TRIF- dependent TLR signalling. 2022 American Crystallographic Association Meeting, Portland, OR USA, 29 July-3 August 2022. Hoboken, NJ USA: Wiley-Blackwell Publishing. doi: 10.1107/s2053273322093196

Structural basis of TIR-domain assembly formation in TRAM- and TRIF- dependent TLR signalling

2019

Conference Publication

Animal TIR domains inform the molecular and structural basis of signaling by plant NLR TIR domains

Kobe, B., Burdett, H., Zhang, X., Chen, J., Rank, M. X., Horsefield, S., Manik, M. K., Shi, Y., Qi, T., Dry, I. B., Williams, S. J., Staskawicz, B. J., Ve, T. and Dodds, P. N. (2019). Animal TIR domains inform the molecular and structural basis of signaling by plant NLR TIR domains. 18th Congress of International Society for Molecular Plant Microbe Interactions (IS-MPMI), Glasgow, Scotland, 14-18 July, 2019. St. Paul, MN, United States: American Phytopathological Society. doi: 10.1094/MPMI-32-10-S1.1

Animal TIR domains inform the molecular and structural basis of signaling by plant NLR TIR domains

2019

Conference Publication

Interaction and structural study between plant TIR-containing NLRs and EDS1 immune regulatory complex

Rank, M. X., Kobe, B., Burdett, H., Horsefield, S., Manik, M. K., Zhang, X. and Shi, Y. (2019). Interaction and structural study between plant TIR-containing NLRs and EDS1 immune regulatory complex. 18th Congress of International Society for Molecular Plant Microbe Interactions (IS-MPMI), Glasgow, Scotland, 14-18 July, 2019. St. Paul, MN, United States: American Phytopathological Society. doi: 10.1094/MPMI-32-10-S1.1

Interaction and structural study between plant TIR-containing NLRs and EDS1 immune regulatory complex

2019

Conference Publication

Self-association and an intact NADase active site are required for plant TIR domain immune signaling

Chen, J., Zhang, X., Burdett, H., Rank, M. X., Ve, T., Rathjen, J., Kobe, B. and Dodds, P. N. (2019). Self-association and an intact NADase active site are required for plant TIR domain immune signaling. 18th Congress of International Society for Molecular Plant Microbe Interactions (IS-MPMI), Glasgow, Scotland, 14-18 July, 2019. St. Paul, MN, United States: American Phytopathological Society. doi: 10.1094/MPMI-32-10-S1.1

Self-association and an intact NADase active site are required for plant TIR domain immune signaling

2019

Conference Publication

Structural and Biochemical Analysis of Plant TIR NAD plus Cleavage Activity

Burdett, H., Rank, M. X., Chen, J., Zhang, X., Shi, Y., Ve, T., Dodds, P. N. and Kobe, B. (2019). Structural and Biochemical Analysis of Plant TIR NAD plus Cleavage Activity. 18th Congress of International Society for Molecular Plant Microbe Interactions (IS-MPMI), Glasgow, Scotland, 14-18 July, 2019. St. Paul, MN, United States: American Phytopathological Society. doi: 10.1094/MPMI-32-10-S1.213

Structural and Biochemical Analysis of Plant TIR NAD plus Cleavage Activity

2018

Conference Publication

Crystallographic and calorimetric studies with nuclear transport of DNA repair proteins

de Mattos Fontes, Marcos Roberto, de Barros, Andrea, Bernardes, Natalia, Takeda, Agnes, Dreyer, Thiago, Bertolini, Maria Celia and Kobe, Bostjan (2018). Crystallographic and calorimetric studies with nuclear transport of DNA repair proteins. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1107/S2053273318092434

Crystallographic and calorimetric studies with nuclear transport of DNA repair proteins