Associate Professor

Lisa Kaminskas

Email: 
Phone: 
+61 7 336 53124

Availability

Associate Professor Lisa Kaminskas is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy, University of Adelaide

Search Professor Lisa Kaminskas’s works on UQ eSpace

97 works between 2000 and 2024
All (97) Journal Article (92) Book Chapter (3) Conference Publication (2)

41 - 60 of 97 works

2017

Journal Article

Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site

Ryan G.M., McLeod V.M., Mehta D., Kelly B.D., Stanislawski P.C., Owen D.J., Kaminskas L.M. and Porter C.J.H. (2017). Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site. Nanomedicine: Nanotechnology, Biology and Medicine, 13 (8), 2485-2494. doi: 10.1016/j.nano.2017.08.003

Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site

2017

Journal Article

Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration

Dong, Yao-Da, Tchung, Estefania, Nowell, Cameron, Kaga, Sadik, Leong, Nathania, Mehta, Dharmini, Kaminskas, Lisa M. and Boyd, Ben J. (2017). Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration. Journal of Liposome Research, 29 (1), 1-9. doi: 10.1080/08982104.2017.1391285

Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration

2017

Journal Article

Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers

Haque, Shadabul, McLeod, Victoria M., Jones, Seth, Fung, Sandy, Whittaker, Michael, McIntosh, Michelle, Pouton, Colin, Owen, David J., Porter, Christopher J. H. and Kaminskas, Lisa M. (2017). Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers. European Journal of Pharmaceutics and Biopharmaceutics, 119, 408-418. doi: 10.1016/j.ejpb.2017.07.005

Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers

2017

Journal Article

Influence of size and shape on the biodistribution of nanoparticles prepared by polymerization-induced self-assembly

Kaga, Sadik, Truong, Nghia P., Esser, Lars, Senyschyn, Danielle, Sanyal, Amitav, Sanyal, Rana, Quinn, John F., Davis, Thomas P., Kaminskas, Lisa M. and Whittaker, Michael R. (2017). Influence of size and shape on the biodistribution of nanoparticles prepared by polymerization-induced self-assembly. Biomacromolecules, 18 (12), 3963-3970. doi: 10.1021/acs.biomac.7b00995

Influence of size and shape on the biodistribution of nanoparticles prepared by polymerization-induced self-assembly

2017

Journal Article

An evaluation of optimal PEGylation strategies for maximizing the lymphatic exposure and antiviral activity of interferon after subcutaneous administration

Chan, Linda J., Feeney, Orlagh M., Leong, Nathania J., McLeod, Victoria M., Porter, Christopher J.H., Williams, Charlotte C. and Kaminskas, Lisa M. (2017). An evaluation of optimal PEGylation strategies for maximizing the lymphatic exposure and antiviral activity of interferon after subcutaneous administration. Biomacromolecules, 18 (9), 2866-2875. doi: 10.1021/acs.biomac.7b00794

An evaluation of optimal PEGylation strategies for maximizing the lymphatic exposure and antiviral activity of interferon after subcutaneous administration

2017

Journal Article

Polymer-drug conjugates as inhalable drug delivery systems: A review

Marasini, Nirmal, Haque, Shadabul and Kaminskas, Lisa M. (2017). Polymer-drug conjugates as inhalable drug delivery systems: A review. Current Opinion in Colloid & Interface Science, 31, 18-29. doi: 10.1016/j.cocis.2017.06.003

Polymer-drug conjugates as inhalable drug delivery systems: A review

2016

Journal Article

Disposition and safety of inhaled biodegradable nanomedicines: opportunities and challenges

Haque, Shadabul, Whittaker, Michael R., McIntosh, Michelle P., Pouton, Colin W. and Kaminskas, Lisa M. (2016). Disposition and safety of inhaled biodegradable nanomedicines: opportunities and challenges. Nanomedicine: Nanotechnology, Biology, and Medicine, 12 (6), 1703-1724. doi: 10.1016/j.nano.2016.03.002

Disposition and safety of inhaled biodegradable nanomedicines: opportunities and challenges

2016

Journal Article

Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation

Kuehl, Christopher, Zhang, Ti, Kaminskas, Lisa M., Porter, Christopher J. H., Davies, Neal M., Forrest, Laird and Berkland, Cory (2016). Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation. Molecular Pharmaceutics, 13 (6), 1904-1914. doi: 10.1021/acs.molpharmaceut.6b00069

Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation

2016

Journal Article

Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab′ Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity

Chan, Linda J., Ascher, David B., Yadav, Rajbharan, Bulitta, Jürgen B., Williams, Charlotte C., Porter, Christopher J. H., Landersdorfer, Cornelia B. and Kaminskas, Lisa M. (2016). Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab′ Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity. Molecular Pharmaceutics, 13 (4), 1229-1241. doi: 10.1021/acs.molpharmaceut.5b00749

Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab′ Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity

2016

Journal Article

A comparison of the pharmacokinetics and pulmonary lymphatic exposure of a generation 4 PEGylated dendrimer following intravenous and aerosol administration to rats and sheep

Ryan, Gemma M., Bischof, Robert J., Enkhbaatar, Perenlei, McLeod, Victoria M., Chan, Linda J., Jones, Seth A., Owen, David J., Porter, Christopher J. H. and Kaminskas, Lisa M. (2016). A comparison of the pharmacokinetics and pulmonary lymphatic exposure of a generation 4 PEGylated dendrimer following intravenous and aerosol administration to rats and sheep. Pharmaceutical Research, 33 (2), 510-525. doi: 10.1007/s11095-015-1806-z

A comparison of the pharmacokinetics and pulmonary lymphatic exposure of a generation 4 PEGylated dendrimer following intravenous and aerosol administration to rats and sheep

2016

Journal Article

Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: the use of polyol, disaccharide, polysaccharide and synthetic polymer to modify solid-state properties for glassy stabilisation

Sou, Tomás, Forbes, Robert T., Gray, Jason, Prankerd, Richard J., Kaminskas, Lisa M., McIntosh, Michelle P. and Morton, David A.V. (2016). Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: the use of polyol, disaccharide, polysaccharide and synthetic polymer to modify solid-state properties for glassy stabilisation. Powder Technology, 287, 248-255. doi: 10.1016/j.powtec.2015.10.008

Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: the use of polyol, disaccharide, polysaccharide and synthetic polymer to modify solid-state properties for glassy stabilisation

2016

Book Chapter

Impact of physicochemical properties on dendrimer pharmacokinetics and biodistribution

Feeney, Orlagh, Caliph, Suzanne M., Porter, Christopher J.H. and Kaminskas, Lisa M. (2016). Impact of physicochemical properties on dendrimer pharmacokinetics and biodistribution. Dendrimers in nanomedicine. (pp. 311-351) edited by Delphine Felder-Flesch. Singapore: Pan Stanford Publishing. doi: 10.1201/9781315364513-9

Impact of physicochemical properties on dendrimer pharmacokinetics and biodistribution

2016

Journal Article

The pharmacokinetics and biodistribution of a 64 kDa PolyPEG star polymer after subcutaneous and pulmonary administration to rats

Khor, Song Yang, Hu, Jinming, McLeod, Victoria M., Quinn, John F., Porter, Christopher J. H., Whittaker, Michael R., Kaminskas, Lisa M. and Davis, Thomas P. (2016). The pharmacokinetics and biodistribution of a 64 kDa PolyPEG star polymer after subcutaneous and pulmonary administration to rats. Journal of Pharmaceutical Sciences, 105 (1), 293-300. doi: 10.1016/j.xphs.2015.11.038

The pharmacokinetics and biodistribution of a 64 kDa PolyPEG star polymer after subcutaneous and pulmonary administration to rats

2015

Journal Article

PEGylated interferon displays differences in plasma clearance and bioavailability between male and female mice and between female immunocompetent C57Bl/6J and athymic nude mice

Landersdorfer, Cornelia B., Caliph, Suzanne M., Shackleford, David M., Ascher, David B. and Kaminskas, Lisa M. (2015). PEGylated interferon displays differences in plasma clearance and bioavailability between male and female mice and between female immunocompetent C57Bl/6J and athymic nude mice. Journal of Pharmaceutical Sciences, 104 (5), 1848-1855. doi: 10.1002/jps.24412

PEGylated interferon displays differences in plasma clearance and bioavailability between male and female mice and between female immunocompetent C57Bl/6J and athymic nude mice

2015

Journal Article

Molecular weight (hydrodynamic volume) dictates the systemic pharmacokinetics and tumour disposition of PolyPEG star polymers

Khor, Song Yang, Hu, Jinming, McLeod, Victoria M., Quinn, John F., Williamson, Mark, Porter, Christopher J. H., Whittaker, Michael R., Kaminskas, Lisa M. and Davis, Thomas P. (2015). Molecular weight (hydrodynamic volume) dictates the systemic pharmacokinetics and tumour disposition of PolyPEG star polymers. Nanomedicine: Nanotechnology, Biology and Medicine, 11 (8), 2099-2108. doi: 10.1016/j.nano.2015.08.001

Molecular weight (hydrodynamic volume) dictates the systemic pharmacokinetics and tumour disposition of PolyPEG star polymers

2015

Journal Article

From sewer to saviour-targeting the lymphatic system to promote drug exposure and activity

Trevaskis, Natalie L., Kaminskas, Lisa M. and Porter, Christopher J. H. (2015). From sewer to saviour-targeting the lymphatic system to promote drug exposure and activity. Nature Reviews Drug Discovery, 14 (11), 781-803. doi: 10.1038/nrd4608

From sewer to saviour-targeting the lymphatic system to promote drug exposure and activity

2015

Journal Article

Spray-dried influenza antigen with trehalose and leucine produces an aerosolizable powder vaccine formulation that induces strong systemic and mucosal immunity after pulmonary administration

Sou, Tomás, Morton, David A.V., Williamson, Mark, Meeusen, Els N., Kaminskas, Lisa M. and McIntosh, Michelle P. (2015). Spray-dried influenza antigen with trehalose and leucine produces an aerosolizable powder vaccine formulation that induces strong systemic and mucosal immunity after pulmonary administration. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 28 (5), 361-371. doi: 10.1089/jamp.2014.1176

Spray-dried influenza antigen with trehalose and leucine produces an aerosolizable powder vaccine formulation that induces strong systemic and mucosal immunity after pulmonary administration

2015

Journal Article

Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration

Mcleod, Victoria M., Chan, Linda J., Ryan, Gemma M., Porter, Christopher J. H. and Kaminskas, Lisa M. (2015). Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration. Journal of Pharmaceutical Sciences, 104 (4), 1421-1430. doi: 10.1002/jps.24353

Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration

2015

Journal Article

Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats

Kaminskas, Lisa M., McLeod, Victoria M., Ascher, David B., Ryan, Gemma M., Jones, Seth, Haynes, John M., Trevaskis, Natalie L., Chan, Linda J., Sloan, Erica K., Finnin, Benjamin A., Williamson, Mark, Velkov, Tony, Williams, Elizabeth D., Kelly, Brian D., Owen, David J. and Porter, Christopher J. H. (2015). Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats. Molecular Pharmaceutics, 12 (2), 432-443. doi: 10.1021/mp500531e

Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats

2015

Journal Article

PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance after subcutaneous administration

Chan, Linda J., Bulitta, Jürgen B., Ascher, David B., Haynes, John Michael, McLeod, Victoria M., Porter, Christopher J. H., Williams, Charlotte C. and Kaminskas, Lisa M. (2015). PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance after subcutaneous administration. Molecular Pharmaceutics, 12 (3), 794-809. doi: 10.1021/mp5006189

PEGylation does not significantly change the initial intravenous or subcutaneous pharmacokinetics or lymphatic exposure of trastuzumab in rats but increases plasma clearance after subcutaneous administration

Current funding

  • 2024 - 2028
    Nanoparticle gene therapy for cystic fibrosis
    NHMRC MRFF PPHR - Chronic Respiratory Conditions
    Open grant

Past funding

  • 2020 - 2021
    UQ AWARE - Dr Lisa Kaminskas
    UQ Amplify Women's Academic Research Equity
    Open grant
  • 2019 - 2021
    A/Prof Lisa Kaminskas - AQ WRAP
    Advance Queensland Women's Research Assistance Program
    Open grant
  • 2019 - 2023
    Understanding the kinetics of nanomedicine clearance from healthy and diseased lungs
    NHMRC Project Grant
    Open grant
  • 2019
    Advanced Brightfield and Fluorescent High Speed and Throughput Slide Scanner for biological, medical, materials science, and agricultural applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2018
    Investigation of the Pharmacokinetics of Avalyn Pharma's Compound in Sheep
    UniQuest Pty Ltd
    Open grant
  • 2017 - 2018
    A Pharmacology Screening Facility to Accelerate Drug Discovery and Development
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2019
    Designing Nanoparticles to Combat Cellular Dysfunction (ARC Discovery Grant administered by Monash University)
    Monash University
    Open grant
  • 2016 - 2020
    Improving cancer survival by optimising drug exposure at sites of cancer metastasis
    NHMRC Career Development Fellowship
    Open grant
  • 2016
    Optimising the therapeutic efficacy of protein-based drugs against lymph-resident diseases.
    NHMRC Project Grant
    Open grant

Availability

Associate Professor Lisa Kaminskas is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

Contact Associate Professor Lisa Kaminskas directly for media enquiries about:

  • cancer drug delivery
  • lung drug delivery
  • lymphatic system drug delivery
  • nanomedicine

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