Dr Neville Butcher
Dr

Neville Butcher

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Availability

Dr Neville Butcher is:
Available for supervision

Fields of research

Biological Sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences

Search Professor Neville Butcher’s works on UQ eSpace

61 works between 1996 and 2024
All (61) Journal Article (54) Book Chapter (4) Conference Publication (3)

1 - 20 of 61 works

2024

Journal Article

Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular Respiration

Choudhury, Chandra, Egleton, James E., Butcher, Neville J., Russell, Angela J. and Minchin, Rodney F. (2024). Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular Respiration. ACS Pharmacology & Translational Science, 7 (8), 2326-2332. doi: 10.1021/acsptsci.4c00282

Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular Respiration

2024

Journal Article

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction

Redd, Meredith A, Yoshikawa, Yusuke, Khan, Nemat, Waqar, Maleeha, Saez, Natalie J, Outhwaite, Jennifer E, Russell, Jake S, Hanna, Amy D, Chiu, Han S, Er, Sing Yan, Butcher, Neville J, Mardon, Karine, Fraser, John F, Smythe, Mark L, Rash, Lachlan D, Thomas, Walter G, King, Glenn F, Reichelt, Melissa E and Palpant, Nathan J (2024). Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction. European Heart Journal, 45 (17), 1571-1574. doi: 10.1093/eurheartj/ehad793

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction

2024

Journal Article

Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platforms

Kaminskas, Lisa M., Butcher, Neville J., Subasic, Christopher N., Kothapalli, Ashok, Haque, Shadabul, Grace, James L., Morsdorf, Alexander, Blanchfield, Joanne T., Whittaker, Andrew K., Quinn, John F. and Whittaker, Michael R. (2024). Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platforms. Expert Opinion On Drug Delivery, 21 (1), 151-167. doi: 10.1080/17425247.2024.2305116

Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platforms

2024

Journal Article

Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity

Ediriweera, Gayathri R., Butcher, Neville J., Kothapalli, Ashok, Zhao, Jiacheng, Blanchfield, Joanne T., Subasic, Christopher N., Grace, James L., Fu, Changkui, Tan, Xiao, Quinn, John F., Ascher, David B., Whittaker, Michael R., Whittaker, Andrew K. and Kaminskas, Lisa M. (2024). Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity. Biomaterials Science, 12 (11), 2978-2992. doi: 10.1039/d3bm02020g

Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity

2024

Book Chapter

Targeting acid-sensing ion channels in disease

Senescall, Victor, Budusan, Elena, Knezic, Adriana, Waqar, Maleeha, Butcher, Neville, Khan, Nemat, McCarthy, Claudia, Widopp, Robert, Karatt-Vellat, Aneesh and Rash, Lachlan D. (2024). Targeting acid-sensing ion channels in disease. Ion channels as targets in drug discovery. (pp. 303-355) edited by Gary Stephens and Edward Stevens. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-52197-3_10

Targeting acid-sensing ion channels in disease

2023

Journal Article

The arylamine N-acetyltransferases as therapeutic targets in metabolic diseases associated with mitochondrial dysfunction

Choudhury, Chandra, Gill, Melinder K., McAleese, Courtney E., Butcher, Neville J., Ngo, Shyuan T., Steyn, Frederik J. and Minchin, Rodney F. (2023). The arylamine N-acetyltransferases as therapeutic targets in metabolic diseases associated with mitochondrial dysfunction. Pharmacological Reviews, 76 (2), 300-320. doi: 10.1124/pharmrev.123.000835

The arylamine N-acetyltransferases as therapeutic targets in metabolic diseases associated with mitochondrial dysfunction

2023

Journal Article

Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in rats

Subasic, Christopher N., Butcher, Neville J., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (9), 4468-4477. doi: 10.1021/acs.molpharmaceut.3c00102

Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in rats

2023

Journal Article

Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration

Ibrahim, Jibriil P., Butcher, Neville J., Kothapalli, Ashok, Subasic, Christopher N., Blanchfield, Joanne T., Whittaker, Andrew K., Whittaker, Michael R and Kaminskas, Lisa M. (2023). Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration. Expert Opinion on Drug Delivery, 20 (8), 1145-1155. doi: 10.1080/17425247.2023.2244881

Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration

2023

Journal Article

Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities

Choudhury, Chandra, McAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2023). Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities. Biochemistry, 62 (14), 2093-2097. doi: 10.1021/acs.biochem.3c00113

Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities

2023

Journal Article

Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats

Subasic, Christopher N., Butcher, Neville J., Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (7), 3494-3504. doi: 10.1021/acs.molpharmaceut.3c00104

Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats

2022

Journal Article

Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis

McAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2022). Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis. Breast Cancer Research and Treatment, 195 (3), 223-236. doi: 10.1007/s10549-022-06668-3

Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis

2022

Journal Article

Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage

Choudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2022). Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage. Biochemical Pharmacology, 200 115020, 115020. doi: 10.1016/j.bcp.2022.115020

Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage

2021

Journal Article

Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins

Subasic, Christopher N., Ardana, Aditya, Chan, Linda J., Huang, Fei, Scoble, Judith A., Butcher, Neville J., Meagher, Laurence, Chiefari, John, Kaminskas, Lisa M. and Williams, Charlotte C. (2021). Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins. International Journal of Pharmaceutics, 608 121075, 121075. doi: 10.1016/j.ijpharm.2021.121075

Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins

2021

Journal Article

Hypoxia-mediated drug resistance in breast cancers

McAleese, Courtney E., Choudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2021). Hypoxia-mediated drug resistance in breast cancers. Cancer Letters, 502, 189-199. doi: 10.1016/j.canlet.2020.11.045

Hypoxia-mediated drug resistance in breast cancers

2021

Journal Article

Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin

Wang, Lili, Butcher, Neville J, Minchin, Rodney F and Kaminskas, Lisa M (2021). Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin. Journal of Pharmaceutical Sciences, 110 (8), 3099-3101. doi: 10.1016/j.xphs.2021.05.009

Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin

2020

Journal Article

Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2

Butcher, Neville J., Burow, Rachel and Minchin, Rodney F. (2020). Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2. Molecular Pharmacology, 98 (2), 88-95. doi: 10.1124/mol.119.119008

Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2

2020

Journal Article

Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function

Idris, Misgana, Mitchell, Deanne J., Gordon, Richard, Sidharthan, Neelima P., Butcher, Neville J. and Minchin, Rodney F. (2020). Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function. Drug Metabolism and Disposition, 48 (5), 337-344. doi: 10.1124/dmd.119.089714

Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function

2020

Journal Article

Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV

Li, Pengcheng, Butcher, Neville J. and Minchin, Rodney F. (2020). Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV. Cell Adhesion and Migration, 14 (1), 1-11. doi: 10.1080/19336918.2019.1710015

Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV

2019

Journal Article

Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α

Li, Pengcheng, Butcher, Neville J. and Minchin, Rod (2019). Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α. Molecular Pharmacology, 96 (5), 573-579. doi: 10.1124/mol.119.117432

Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α

2019

Journal Article

Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex

Wang, Lili, Minchin, Rodney F., Essebier, Patricia J. and Butcher, Neville J. (2019). Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex. International Journal of Biochemistry and Cell Biology, 110, 84-90. doi: 10.1016/j.biocel.2019.03.002

Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex

Past funding

  • 2016 - 2019
    The pharmacology of sulfotransferase 4A1
    NHMRC Project Grant
    Open grant
  • 2015 - 2017
    Role of sirtuins in the regulation of the carcinogen metabolising arylamine N-acetyltransferases
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Role of the drug metabolising enzyme arylamine N-acetyltransferase 1 in breast cancer
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    ResTeach 2011 0.1 FTE School of Biomedical Sciences
    UQ ResTeach
    Open grant
  • 2009 - 2012
    Pharmacological Targeting of Arylamine N-Acetyltransferase I
    NHMRC Project Grant
    Open grant

Availability

Dr Neville Butcher is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Charaterisation of ion channels as pattern recognition receptors for acidosis and potential anti-inflammatory targets.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Understanding the role acid-sensing ion channels in disease progression and pain associated with neuroinflammatory conditions.

    Associate Advisor

    Other advisors: Emeritus Professor Maree Smith, Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Developing novel acid-sensing ion channel inhibitors as neuroprotective leads and diagnostic agents for multiple sclerosis.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Developing novel acid-sensing ion channel inhibitors as neuroprotective leads and diagnostic agents for multiple sclerosis.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

Completed supervision

Enquiries

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