Dr Neville Butcher
Dr

Neville Butcher

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Availability

Dr Neville Butcher is:
Available for supervision

Fields of research

Biological Sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences

Search Professor Neville Butcher’s works on UQ eSpace

66 works between 1996 and 2025
All (66) Journal Article (55) Book Chapter (4) Conference Publication (7)

41 - 60 of 66 works

2014

Conference Publication

Targeting the Arylamine N-Acetyltransferases in Cancer

Minchin, Rodney F. and Butcher, Neville J. (2014). Targeting the Arylamine N-Acetyltransferases in Cancer. 10th International Meeting of the International Society for the Study of Xenobiotics (ISSX), Toronto, Canada, 29 September - 03 October 2013. New York, United States: Informa Healthcare.

Targeting the Arylamine N-Acetyltransferases in Cancer

2014

Journal Article

Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials

Deng, Zhou J., Butcher, Neville J., Mortimer, Gysell M., Jia, Zhongfan, Monteiro, Michael J., Martin, Darren J. and Minchin, Rodney F. (2014). Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials. Drug Metabolism and Disposition, 42 (3), 377-383. doi: 10.1124/dmd.113.055988

Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials

2013

Journal Article

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling

Sidharthan, Neelima P., Minchin, Rodney F. and Butcher, Neville J. (2013). Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling. Journal of Biological Chemistry, 288 (48), 34364-34374. doi: 10.1074/jbc.M113.493239

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling

2013

Journal Article

5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion

Witham, Katey L., Butcher, Neville J., Sugamori, Kim S., Brenneman, Debbie, Grant, Denis M. and Minchin, Rodney F. (2013). 5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion. PLoS One, 8 (10) e77923, e77923.1-e77923.7. doi: 10.1371/journal.pone.0077923

5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion

2012

Journal Article

Arylamine N-acetyltransferase 1: A novel drug target in cancer development

Butcher, Neville J. and Minchin, Rodney F. (2012). Arylamine N-acetyltransferase 1: A novel drug target in cancer development. Pharmacological Reviews, 64 (1), 147-165. doi: 10.1124/pr.110.004275

Arylamine N-acetyltransferase 1: A novel drug target in cancer development

2011

Journal Article

RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition

Tiang, JM, Butcher, NJ, Cullinane, C, Humbert, PO and Minchin, RF (2011). RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition. PLoS One, 6 (2) e17031, 1-10. doi: 10.1371/journal.pone.0017031

RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition

2011

Journal Article

Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells

Paterson, S, Sin, KL, Tiang, JM, Minchin, RF and Butcher, NJ (2011). Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells. Drug Metabolism and Disposition, 39 (1), 77-82. doi: 10.1124/dmd.110.036202

Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells

2011

Journal Article

Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A

Mitchell, Deanne J., Butcher, Neville J. and Minchin, Rodney F. (2011). Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A. Biochimica et Biophysica Acta - Molecular Cell Research, 1813 (1), 231-237. doi: 10.1016/j.bbamcr.2010.09.011

Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A

2010

Journal Article

Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2

Butcher, Neville J., Mitchell, Deanne J., Burow, Rachel and Minchin, Rodney F. (2010). Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2. Molecular Pharmacology, 78 (3), 503-510. doi: 10.1124/mol.110.063404

Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2

2010

Journal Article

Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1

Butcher, Neville J. and Minchin, Rodney F. (2010). Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1. Carcinogenesis, 31 (5), 820-826. doi: 10.1093/carcin/bgq042

Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1

2010

Journal Article

Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells

Tiang, Jacky M., Butcher, Neville J. and Minchin, Rodney F. (2010). Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells. Biochemical and Biophysical Research Communications, 393 (1), 95-100. doi: 10.1016/j.bbrc.2010.01.087

Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells

2008

Journal Article

Regulation of arylamine N-acetyltransferases

Butcher, Neville J., Tiang, Jacky and Minchin, Rodney F. (2008). Regulation of arylamine N-acetyltransferases. Current Drug Metabolism, 9 (6), 498-504. doi: 10.2174/138920008784892128

Regulation of arylamine N-acetyltransferases

2008

Conference Publication

Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop

Boukouvala, S., Westwood, I. M., Butcher, N. J. and Fakis, G. U. (2008). Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop. The United Kingdom: Future Medicine Limited. doi: 10.2217/14622416.9.6.765

Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop

2008

Book Chapter

Arylamine N-Acetyltransferases

Butcher, Neville J. and Minchin, Rodney F. (2008). Arylamine N-Acetyltransferases. Encyclopedia of cancer. (pp. 255-257) edited by Manfred Schwab. Berlin, Germany: Springer Verlag. doi: 10.1007/978-3-540-47648-1_408

Arylamine N-Acetyltransferases

2007

Journal Article

Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation

Butcher, Neville J., Broadhurst, Gysell M. and Minchin, Rodney F. (2007). Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation. Journal of Biological Chemistry, 282 (39), 28530-28539. doi: 10.1074/jbc.M701265200

Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation

2007

Journal Article

Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells

Butcher, Neville J., Tetlow, Natasha L., Cheung, Catherine, Broadhurst, Gysell M. and Minchin, Rodney F. (2007). Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells. Cancer Research, 67 (1), 85-92. doi: 10.1158/0008-5472.CAN-06-2635

Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells

2007

Journal Article

Arylamine N-acetyltransferase I

Minchin, RF, Hanna, PE, Dupret, JM, Wagner, CR, Rodrigues-Lima, F and Butcher, NJ (2007). Arylamine N-acetyltransferase I. International Journal of Biochemistry & Cell Biology, 39 (11), 1999-2005. doi: 10.1016/j.biocel.2006.12.006

Arylamine N-acetyltransferase I

2005

Journal Article

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities

Butcher, N. J., Arulpragasam, A., Goh, H. L., Davey, Tamara and Minchin, Rodney F. (2005). Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities. Biochemical Journal, 387 (1), 119-127. doi: 10.1042/BJ20040903

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities

2005

Book Chapter

Arylamine N-Acetyltransferase Gene Polymorphism

Butcher, N. J. and Minchin, R. F. (2005). Arylamine N-Acetyltransferase Gene Polymorphism. Encyclopedia of Medical Genomics and Proteomics. (pp. 79-83) edited by Jurgen Fuchs and Maurizio Podda. New York: Marcel Dekker.

Arylamine N-Acetyltransferase Gene Polymorphism

2004

Journal Article

Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation

Butcher, Neville J., Arulpragasam, Ajanthy and Minchin, Rodney F. (2004). Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation. Journal of Biological Chemistry, 279 (21), 22131-22137. doi: 10.1074/jbc.M312858200

Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation

Past funding

  • 2016 - 2019
    The pharmacology of sulfotransferase 4A1
    NHMRC Project Grant
    Open grant
  • 2015 - 2017
    Role of sirtuins in the regulation of the carcinogen metabolising arylamine N-acetyltransferases
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Role of the drug metabolising enzyme arylamine N-acetyltransferase 1 in breast cancer
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    ResTeach 2011 0.1 FTE School of Biomedical Sciences
    UQ ResTeach
    Open grant
  • 2009 - 2012
    Pharmacological Targeting of Arylamine N-Acetyltransferase I
    NHMRC Project Grant
    Open grant

Availability

Dr Neville Butcher is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Charaterisation of ion channels as pattern recognition receptors for acidosis and potential anti-inflammatory targets.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Developing novel acid-sensing ion channel inhibitors as neuroprotective leads and diagnostic agents for multiple sclerosis.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Developing novel acid-sensing ion channel inhibitors as neuroprotective leads and diagnostic agents for multiple sclerosis.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Understanding the role acid-sensing ion channels in disease progression and pain associated with neuroinflammatory conditions.

    Associate Advisor

    Other advisors: Emeritus Professor Maree Smith, Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Inhalable nanoparticle-based gene delivery system for cystic fibrosis

    Associate Advisor

    Other advisors: Professor Kristofer Thurecht, Associate Professor Lisa Kaminskas

Completed supervision

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