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2026 Journal Article The nanobody Nb.C1 potentiates human acid-sensing ion channel 1a and 1bGolder, Mimi, Butcher, Neville J., Naughton, Jennifer D., Liu, Junyu, Crawford, Theo, Rash, Lachlan D., Mobli, Mehdi and Cristofori-Armstrong, Ben (2026). The nanobody Nb.C1 potentiates human acid-sensing ion channel 1a and 1b. European Journal of Pharmacology, 1022 178850, 178850-1022. doi: 10.1016/j.ejphar.2026.178850 |
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2026 Journal Article The Isolated Thumb Domain of Acid‐Sensing Ion Channels Forms a Minimal Folding Unit Enabling Ligand Binding StudiesMishra, Biswa P., Cristofori‐Armstrong, Ben, Budusan, Elena, Golder, Mimi, Butcher, Neville J., Liu, Junyu, Crawford, Theo, Chin, Yanni K.‐Y., Pereira Schmidt, Anneka, Jia, Xinying, Smallwood, Taylor B., Clark, Richard J., Wurm, Jan P., Rash, Lachlan D. and Mobli, Mehdi (2026). The Isolated Thumb Domain of Acid‐Sensing Ion Channels Forms a Minimal Folding Unit Enabling Ligand Binding Studies. Angewandte Chemie International Edition e23977, 1-12. doi: 10.1002/anie.202523977 |
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2026 Journal Article Inhalable gene and RNA therapy for cystic fibrosis: perspectives and progress in clinical developmentMunir, Miftakul, Butcher, Neville J., Werder, Rhiannon B., Ranganathan, Sarath C., Burow, Rachel, Venables, Andrew and Kaminskas, Lisa M. (2026). Inhalable gene and RNA therapy for cystic fibrosis: perspectives and progress in clinical development. Nanomedicine, 21 (7), 1003-1025. doi: 10.1080/17435889.2026.2640157 |
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2025 Journal Article Arylamine N-acetyltransferase 1 expression predicts glucose dependence and mitochondrial bioenergetics in cancer cellsChoudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2025). Arylamine N-acetyltransferase 1 expression predicts glucose dependence and mitochondrial bioenergetics in cancer cells. Biochimica et Biophysica Acta - Molecular Cell Research, 1872 (4) 119929, 119929. doi: 10.1016/j.bbamcr.2025.119929 |
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2024 Conference Publication Insights into the role of acid sensing ion channels in the pathophysiology of multiple sclerosisWaqar, Maleeha, Khan, Nemat, Butcher, Neville and Rash, Lachlan (2024). Insights into the role of acid sensing ion channels in the pathophysiology of multiple sclerosis. Multiple Sclerosis Australia: Progress in MS Research Conference (MS), Perth, WA, Australia, 29 November-1 December 2023. London, United Kingdom: Sage Publications. |
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2024 Conference Publication Development of venom peptide inhibitors of acid-sensing ion channel 1 as novel therapeutics for multiple sclerosisRash, Lachlan, Waqar, Maleeha, Butcher, Neville and Khan, Nemat (2024). Development of venom peptide inhibitors of acid-sensing ion channel 1 as novel therapeutics for multiple sclerosis. Multiple Sclerosis Australia: Progress in MS Research Conference (MS), Perth, WA, Australia, 29 November-1 December 2023. London, United Kingdom: Sage Publications. |
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2024 Conference Publication Developing novel acid-sensing ion channel inhibitor as a neuroprotective lead for multiple sclerosisKhan, Nemat, Waqar, Maleeha, Butcher, Neville and Rash, Lachlan (2024). Developing novel acid-sensing ion channel inhibitor as a neuroprotective lead for multiple sclerosis. 40th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Copenhagen, Denmark, 18-20 September 2024. London, United Kingdom: Sage Publications. doi: 10.1177/13524585241269220 |
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2024 Conference Publication Understanding the role of acid sensing ion channels as targets of neuroprotection in the pathophysiology of multiple sclerosisWaqar, Maleeha, Rash, Lachlan, Butcher, Neville and Khan, Nemat (2024). Understanding the role of acid sensing ion channels as targets of neuroprotection in the pathophysiology of multiple sclerosis. 40th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Copenhagen, Denmark, 18-20 September 2024. London, United Kingdom: Sage Publications. doi: 10.1177/13524585241269220 |
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2024 Journal Article Small molecule inhibitors of arylamine N-acetyltransferase 1 attenuate cellular respirationChoudhury, Chandra, Egleton, James E., Butcher, Neville J., Russell, Angela J. and Minchin, Rodney F. (2024). Small molecule inhibitors of arylamine N-acetyltransferase 1 attenuate cellular respiration. ACS Pharmacology & Translational Science, 7 (8), 2326-2332. doi: 10.1021/acsptsci.4c00282 |
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2024 Journal Article Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarctionRedd, Meredith A, Yoshikawa, Yusuke, Khan, Nemat, Waqar, Maleeha, Saez, Natalie J, Outhwaite, Jennifer E, Russell, Jake S, Hanna, Amy D, Chiu, Han S, Er, Sing Yan, Butcher, Neville J, Mardon, Karine, Fraser, John F, Smythe, Mark L, Rash, Lachlan D, Thomas, Walter G, King, Glenn F, Reichelt, Melissa E and Palpant, Nathan J (2024). Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction. European Heart Journal, 45 (17), 1571-1574. doi: 10.1093/eurheartj/ehad793 |
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2024 Journal Article The arylamine N-acetyltransferases as therapeutic targets in metabolic diseases associated with mitochondrial dysfunctionChoudhury, Chandra, Gill, Melinder K., McAleese, Courtney E., Butcher, Neville J., Ngo, Shyuan T., Steyn, Frederik J. and Minchin, Rodney F. (2024). The arylamine N-acetyltransferases as therapeutic targets in metabolic diseases associated with mitochondrial dysfunction. Pharmacological Reviews, 76 (2), 300-320. doi: 10.1124/pharmrev.123.000835 |
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2024 Journal Article Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platformsKaminskas, Lisa M., Butcher, Neville J., Subasic, Christopher N., Kothapalli, Ashok, Haque, Shadabul, Grace, James L., Morsdorf, Alexander, Blanchfield, Joanne T., Whittaker, Andrew K., Quinn, John F. and Whittaker, Michael R. (2024). Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platforms. Expert Opinion On Drug Delivery, 21 (1), 151-167. doi: 10.1080/17425247.2024.2305116 |
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2024 Journal Article Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinityEdiriweera, Gayathri R., Butcher, Neville J., Kothapalli, Ashok, Zhao, Jiacheng, Blanchfield, Joanne T., Subasic, Christopher N., Grace, James L., Fu, Changkui, Tan, Xiao, Quinn, John F., Ascher, David B., Whittaker, Michael R., Whittaker, Andrew K. and Kaminskas, Lisa M. (2024). Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity. Biomaterials Science, 12 (11), 2978-2992. doi: 10.1039/d3bm02020g |
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2024 Book Chapter Targeting acid-sensing ion channels in diseaseSenescall, Victor, Budusan, Elena, Knezic, Adriana, Waqar, Maleeha, Butcher, Neville, Khan, Nemat, McCarthy, Claudia, Widopp, Robert, Karatt-Vellat, Aneesh and Rash, Lachlan D. (2024). Targeting acid-sensing ion channels in disease. Ion channels as targets in drug discovery. (pp. 303-355) edited by Gary Stephens and Edward Stevens. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-52197-3_10 |
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2023 Journal Article Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in ratsSubasic, Christopher N., Butcher, Neville J., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (9), 4468-4477. doi: 10.1021/acs.molpharmaceut.3c00102 |
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2023 Journal Article Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administrationIbrahim, Jibriil P., Butcher, Neville J., Kothapalli, Ashok, Subasic, Christopher N., Blanchfield, Joanne T., Whittaker, Andrew K., Whittaker, Michael R and Kaminskas, Lisa M. (2023). Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration. Expert Opinion on Drug Delivery, 20 (8), 1145-1155. doi: 10.1080/17425247.2023.2244881 |
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2023 Journal Article Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activitiesChoudhury, Chandra, McAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2023). Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities. Biochemistry, 62 (14), 2093-2097. doi: 10.1021/acs.biochem.3c00113 |
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2023 Journal Article Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in ratsSubasic, Christopher N., Butcher, Neville J., Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (7), 3494-3504. doi: 10.1021/acs.molpharmaceut.3c00104 |
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2022 Journal Article Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosisMcAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2022). Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis. Breast Cancer Research and Treatment, 195 (3), 223-236. doi: 10.1007/s10549-022-06668-3 |
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2022 Journal Article Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usageChoudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2022). Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage. Biochemical Pharmacology, 200 115020, 115020. doi: 10.1016/j.bcp.2022.115020 |
