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2014

Conference Publication

Targeting the Arylamine N-Acetyltransferases in Cancer

Minchin, Rodney F. and Butcher, Neville J. (2014). Targeting the Arylamine N-Acetyltransferases in Cancer. 10th International Meeting of the International Society for the Study of Xenobiotics (ISSX), Toronto, Canada, 29 September - 03 October 2013. New York, United States: Informa Healthcare.

Targeting the Arylamine N-Acetyltransferases in Cancer

2014

Journal Article

Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials

Deng, Zhou J., Butcher, Neville J., Mortimer, Gysell M., Jia, Zhongfan, Monteiro, Michael J., Martin, Darren J. and Minchin, Rodney F. (2014). Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials. Drug Metabolism and Disposition, 42 (3), 377-383. doi: 10.1124/dmd.113.055988

Interaction of human arylamine n-acetyltransferase 1 with different nanomaterials

2013

Journal Article

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling

Sidharthan, Neelima P., Minchin, Rodney F. and Butcher, Neville J. (2013). Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling. Journal of Biological Chemistry, 288 (48), 34364-34374. doi: 10.1074/jbc.M113.493239

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: Role of D1 receptor-n-methyl-d-aspartate receptor coupling

2013

Journal Article

5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion

Witham, Katey L., Butcher, Neville J., Sugamori, Kim S., Brenneman, Debbie, Grant, Denis M. and Minchin, Rodney F. (2013). 5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion. PLoS One, 8 (10) e77923, e77923.1-e77923.7. doi: 10.1371/journal.pone.0077923

5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion

2012

Journal Article

Arylamine N-acetyltransferase 1: A novel drug target in cancer development

Butcher, Neville J. and Minchin, Rodney F. (2012). Arylamine N-acetyltransferase 1: A novel drug target in cancer development. Pharmacological Reviews, 64 (1), 147-165. doi: 10.1124/pr.110.004275

Arylamine N-acetyltransferase 1: A novel drug target in cancer development

2011

Journal Article

RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition

Tiang, JM, Butcher, NJ, Cullinane, C, Humbert, PO and Minchin, RF (2011). RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition. PLoS One, 6 (2) e17031, 1-10. doi: 10.1371/journal.pone.0017031

RNAi-mediated knock-down of Arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibition

2011

Journal Article

Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells

Paterson, S, Sin, KL, Tiang, JM, Minchin, RF and Butcher, NJ (2011). Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells. Drug Metabolism and Disposition, 39 (1), 77-82. doi: 10.1124/dmd.110.036202

Histone deacetylase inhibitors increase human arylamine N-acetyltransferase-1 expression in human tumor cells

2011

Journal Article

Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A

Mitchell, Deanne J., Butcher, Neville J. and Minchin, Rodney F. (2011). Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A. Biochimica et Biophysica Acta - Molecular Cell Research, 1813 (1), 231-237. doi: 10.1016/j.bbamcr.2010.09.011

Phosphorylation/dephosphorylation of human SULT4A1: Role of Erk1 and PP2A

2010

Journal Article

Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2

Butcher, Neville J., Mitchell, Deanne J., Burow, Rachel and Minchin, Rodney F. (2010). Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2. Molecular Pharmacology, 78 (3), 503-510. doi: 10.1124/mol.110.063404

Regulation of Mouse Brain-Selective Sulfotransferase Sult4a1 by cAMP Response Element-Binding Protein and Activating Transcription Factor-2

2010

Journal Article

Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1

Butcher, Neville J. and Minchin, Rodney F. (2010). Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1. Carcinogenesis, 31 (5), 820-826. doi: 10.1093/carcin/bgq042

Arylamine N-acetyltransferase 1 gene regulation by androgens requires a conserved heat shock element for heat shock factor-1

2010

Journal Article

Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells

Tiang, Jacky M., Butcher, Neville J. and Minchin, Rodney F. (2010). Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells. Biochemical and Biophysical Research Communications, 393 (1), 95-100. doi: 10.1016/j.bbrc.2010.01.087

Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells

2008

Journal Article

Regulation of arylamine N-acetyltransferases

Butcher, Neville J., Tiang, Jacky and Minchin, Rodney F. (2008). Regulation of arylamine N-acetyltransferases. Current Drug Metabolism, 9 (6), 498-504. doi: 10.2174/138920008784892128

Regulation of arylamine N-acetyltransferases

2008

Conference Publication

Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop

Boukouvala, S., Westwood, I. M., Butcher, N. J. and Fakis, G. U. (2008). Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop. The United Kingdom: Future Medicine Limited. doi: 10.2217/14622416.9.6.765

Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop

2008

Book Chapter

Arylamine N-Acetyltransferases

Butcher, Neville J. and Minchin, Rodney F. (2008). Arylamine N-Acetyltransferases. Encyclopedia of cancer. (pp. 255-257) edited by Manfred Schwab. Berlin, Germany: Springer Verlag. doi: 10.1007/978-3-540-47648-1_408

Arylamine N-Acetyltransferases

2007

Journal Article

Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation

Butcher, Neville J., Broadhurst, Gysell M. and Minchin, Rodney F. (2007). Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation. Journal of Biological Chemistry, 282 (39), 28530-28539. doi: 10.1074/jbc.M701265200

Polyamine-dependent regulation of spermidine-spermine N-1-acetyltransferase mRNA translation

2007

Journal Article

Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells

Butcher, Neville J., Tetlow, Natasha L., Cheung, Catherine, Broadhurst, Gysell M. and Minchin, Rodney F. (2007). Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells. Cancer Research, 67 (1), 85-92. doi: 10.1158/0008-5472.CAN-06-2635

Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells

2007

Journal Article

Arylamine N-acetyltransferase I

Minchin, RF, Hanna, PE, Dupret, JM, Wagner, CR, Rodrigues-Lima, F and Butcher, NJ (2007). Arylamine N-acetyltransferase I. International Journal of Biochemistry & Cell Biology, 39 (11), 1999-2005. doi: 10.1016/j.biocel.2006.12.006

Arylamine N-acetyltransferase I

2005

Journal Article

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities

Butcher, N. J., Arulpragasam, A., Goh, H. L., Davey, Tamara and Minchin, Rodney F. (2005). Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities. Biochemical Journal, 387 (1), 119-127. doi: 10.1042/BJ20040903

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities

2005

Book Chapter

Arylamine N-Acetyltransferase Gene Polymorphism

Butcher, N. J. and Minchin, R. F. (2005). Arylamine N-Acetyltransferase Gene Polymorphism. Encyclopedia of Medical Genomics and Proteomics. (pp. 79-83) edited by Jurgen Fuchs and Maurizio Podda. New York: Marcel Dekker.

Arylamine N-Acetyltransferase Gene Polymorphism

2004

Journal Article

Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation

Butcher, Neville J., Arulpragasam, Ajanthy and Minchin, Rodney F. (2004). Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation. Journal of Biological Chemistry, 279 (21), 22131-22137. doi: 10.1074/jbc.M312858200

Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation