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2023

Journal Article

Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration

Ibrahim, Jibriil P., Butcher, Neville J., Kothapalli, Ashok, Subasic, Christopher N., Blanchfield, Joanne T., Whittaker, Andrew K., Whittaker, Michael R and Kaminskas, Lisa M. (2023). Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration. Expert Opinion on Drug Delivery, 20 (8), 1145-1155. doi: 10.1080/17425247.2023.2244881

Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration

2023

Journal Article

Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities

Choudhury, Chandra, McAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2023). Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities. Biochemistry, 62 (14), 2093-2097. doi: 10.1021/acs.biochem.3c00113

Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities

2023

Journal Article

Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats

Subasic, Christopher N., Butcher, Neville J., Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (7), 3494-3504. doi: 10.1021/acs.molpharmaceut.3c00104

Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats

2022

Journal Article

Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis

McAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2022). Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis. Breast Cancer Research and Treatment, 195 (3), 223-236. doi: 10.1007/s10549-022-06668-3

Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis

2022

Journal Article

Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage

Choudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2022). Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage. Biochemical Pharmacology, 200 115020, 115020. doi: 10.1016/j.bcp.2022.115020

Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage

2021

Journal Article

Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins

Subasic, Christopher N., Ardana, Aditya, Chan, Linda J., Huang, Fei, Scoble, Judith A., Butcher, Neville J., Meagher, Laurence, Chiefari, John, Kaminskas, Lisa M. and Williams, Charlotte C. (2021). Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins. International Journal of Pharmaceutics, 608 121075, 121075. doi: 10.1016/j.ijpharm.2021.121075

Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins

2021

Journal Article

Hypoxia-mediated drug resistance in breast cancers

McAleese, Courtney E., Choudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2021). Hypoxia-mediated drug resistance in breast cancers. Cancer Letters, 502, 189-199. doi: 10.1016/j.canlet.2020.11.045

Hypoxia-mediated drug resistance in breast cancers

2021

Journal Article

Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin

Wang, Lili, Butcher, Neville J, Minchin, Rodney F and Kaminskas, Lisa M (2021). Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin. Journal of Pharmaceutical Sciences, 110 (8), 3099-3101. doi: 10.1016/j.xphs.2021.05.009

Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin

2020

Journal Article

Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2

Butcher, Neville J., Burow, Rachel and Minchin, Rodney F. (2020). Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2. Molecular Pharmacology, 98 (2), 88-95. doi: 10.1124/mol.119.119008

Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2

2020

Journal Article

Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function

Idris, Misgana, Mitchell, Deanne J., Gordon, Richard, Sidharthan, Neelima P., Butcher, Neville J. and Minchin, Rodney F. (2020). Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function. Drug Metabolism and Disposition, 48 (5), 337-344. doi: 10.1124/dmd.119.089714

Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function

2020

Journal Article

Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV

Li, Pengcheng, Butcher, Neville J. and Minchin, Rodney F. (2020). Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV. Cell Adhesion and Migration, 14 (1), 1-11. doi: 10.1080/19336918.2019.1710015

Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV

2019

Journal Article

Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α

Li, Pengcheng, Butcher, Neville J. and Minchin, Rod (2019). Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α. Molecular Pharmacology, 96 (5), 573-579. doi: 10.1124/mol.119.117432

Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α

2019

Journal Article

Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex

Wang, Lili, Minchin, Rodney F., Essebier, Patricia J. and Butcher, Neville J. (2019). Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex. International Journal of Biochemistry and Cell Biology, 110, 84-90. doi: 10.1016/j.biocel.2019.03.002

Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex

2019

Journal Article

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Kaminskas, Lisa M., Williams, Charlotte C., Leong, Nathania J., Chan, Linda J., Butcher, Neville J., Feeney, Orlagh M., Porter, Christopher J.H., Tyssen, David, Tachedjian, Gilda and Ascher, David B. (2019). A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats. European Journal of Pharmaceutics and Biopharmaceutics, 137, 218-226. doi: 10.1016/j.ejpb.2019.03.008

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

2019

Journal Article

The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation

Idris, Misgana, Butcher, Neville J and Minchin, Rodney F (2019). The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation. Drug Metabolism and Disposition, 47 (3), 314-319. doi: 10.1124/dmd.118.085290

The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation

2019

Conference Publication

Regulation of MMP9 expression by human arylamine N-acetyltransferase (NAT1) via Hif-1a

Li, P., Minchin, R. F. and Butcher, N. (2019). Regulation of MMP9 expression by human arylamine N-acetyltransferase (NAT1) via Hif-1a. ESMO Breast Cancer, Berlin, Germany, 2-4 May 2019 . Amsterdam, Netherlands: Elsevier.

Regulation of MMP9 expression by human arylamine N-acetyltransferase (NAT1) via Hif-1a

2018

Journal Article

Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate

Minchin, Rodney F., Rosengren, K. Johan, Burow, Rachel and Butcher, Neville J. (2018). Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate. Biochemical Pharmacology, 158, 153-160. doi: 10.1016/j.bcp.2018.10.013

Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate

2018

Journal Article

Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance

Minchin, Rodney F. and Butcher, Neville J. (2018). Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance. BMC Genomics, 19 (1) 513, 513. doi: 10.1186/s12864-018-4894-4

Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance

2018

Journal Article

Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability

Wang, LiLi, Minchin, Rodney F and Butcher, Neville J (2018). Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability. PLoS One, 13 (3) e0193560, e0193560. doi: 10.1371/journal.pone.0193560

Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability

2018

Book Chapter

Human Arylamine N-Acetyltransferase Type 1

Butcher, Neville J., Li, Pengcheng, Wang, Lili and Minchin, Rodney F. (2018). Human Arylamine N-Acetyltransferase Type 1. Arylamine N-acetyltransferases in Health and Disease: From Pharmacogenetics to Drug Discovery and Diagnostics. (pp. 91-107) edited by Nicola Laurieri and Edith Sim. Singapore: World Scientific Publishing. doi: 10.1142/9789813232013_0004

Human Arylamine N-Acetyltransferase Type 1