|
2005 Journal Article Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activitiesButcher, N. J., Arulpragasam, A., Goh, H. L., Davey, Tamara and Minchin, Rodney F. (2005). Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities. Biochemical Journal, 387 (1), 119-127. doi: 10.1042/BJ20040903 |
|
2005 Book Chapter Arylamine N-Acetyltransferase Gene PolymorphismButcher, N. J. and Minchin, R. F. (2005). Arylamine N-Acetyltransferase Gene Polymorphism. Encyclopedia of Medical Genomics and Proteomics. (pp. 79-83) edited by Jurgen Fuchs and Maurizio Podda. New York: Marcel Dekker. |
|
2004 Journal Article Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulationButcher, Neville J., Arulpragasam, Ajanthy and Minchin, Rodney F. (2004). Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine - A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation. Journal of Biological Chemistry, 279 (21), 22131-22137. doi: 10.1074/jbc.M312858200 |
|
2003 Journal Article Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1)Butcher, NJ, Arulpragasam, A, Pope, C and Minchin, RF (2003). Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1). Biochemical Journal, 376 (2), 441-448. doi: 10.1042/BJ20030650 |
|
2002 Journal Article Pharmacogenetics of the arylamine N-acetyltransferasesButcher, N. J., Boukouvala, S., Sim, E. and Minchin, R. F. (2002). Pharmacogenetics of the arylamine N-acetyltransferases. Pharmacogenomics Journal, 2 (1), 30-42. doi: 10.1038/sj.tpj.6500053 |
|
2000 Journal Article Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cellsButcher, NJ, Ilett, KF and Minchin, RF (2000). Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells. Molecular Pharmacology, 57 (3), 468-473. doi: 10.1124/mol.57.3.468 |
|
2000 Journal Article Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acidButcher, NJ, Ilett, KF and Minchin, RF (2000). Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acid. Biochemical Pharmacology, 60 (12), 1829-1836. doi: 10.1016/S0006-2952(00)00501-3 |
|
1998 Journal Article Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by (CT)-T-190 and G(560)A mutationsButcher, NJ, Ilett, KF and Minchin, RF (1998). Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by (CT)-T-190 and G(560)A mutations. Pharmacogenetics, 8 (1), 67-72. doi: 10.1097/00008571-199802000-00009 |
|
1996 Journal Article Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitroButcher, N.J., Minchin, R.F., Kadlubar, F.F. and llett , K.F. (1996). Uptake of the food-derived heterocyclic amine carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and its N-hydroxy metabolite into rat pancreatic acini and hepatocytes in vitro. Carcinogenesis, 17 (4), 889-992. doi: 10.1093/carcin/17.4.889 |
