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2024 Journal Article Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular RespirationChoudhury, Chandra, Egleton, James E., Butcher, Neville J., Russell, Angela J. and Minchin, Rodney F. (2024). Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular Respiration. ACS Pharmacology & Translational Science, 7 (8), 2326-2332. doi: 10.1021/acsptsci.4c00282 |
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2024 Journal Article Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarctionRedd, Meredith A, Yoshikawa, Yusuke, Khan, Nemat, Waqar, Maleeha, Saez, Natalie J, Outhwaite, Jennifer E, Russell, Jake S, Hanna, Amy D, Chiu, Han S, Er, Sing Yan, Butcher, Neville J, Mardon, Karine, Fraser, John F, Smythe, Mark L, Rash, Lachlan D, Thomas, Walter G, King, Glenn F, Reichelt, Melissa E and Palpant, Nathan J (2024). Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction. European Heart Journal, 45 (17), 1571-1574. doi: 10.1093/eurheartj/ehad793 |
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2024 Journal Article Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platformsKaminskas, Lisa M., Butcher, Neville J., Subasic, Christopher N., Kothapalli, Ashok, Haque, Shadabul, Grace, James L., Morsdorf, Alexander, Blanchfield, Joanne T., Whittaker, Andrew K., Quinn, John F. and Whittaker, Michael R. (2024). Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platforms. Expert Opinion On Drug Delivery, 21 (1), 151-167. doi: 10.1080/17425247.2024.2305116 |
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2024 Journal Article Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinityEdiriweera, Gayathri R., Butcher, Neville J., Kothapalli, Ashok, Zhao, Jiacheng, Blanchfield, Joanne T., Subasic, Christopher N., Grace, James L., Fu, Changkui, Tan, Xiao, Quinn, John F., Ascher, David B., Whittaker, Michael R., Whittaker, Andrew K. and Kaminskas, Lisa M. (2024). Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity. Biomaterials Science, 12 (11), 2978-2992. doi: 10.1039/d3bm02020g |
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2023 Journal Article The arylamine N-acetyltransferases as therapeutic targets in metabolic diseases associated with mitochondrial dysfunctionChoudhury, Chandra, Gill, Melinder K., McAleese, Courtney E., Butcher, Neville J., Ngo, Shyuan T., Steyn, Frederik J. and Minchin, Rodney F. (2023). The arylamine N-acetyltransferases as therapeutic targets in metabolic diseases associated with mitochondrial dysfunction. Pharmacological Reviews, 76 (2), 300-320. doi: 10.1124/pharmrev.123.000835 |
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2023 Journal Article Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in ratsSubasic, Christopher N., Butcher, Neville J., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (9), 4468-4477. doi: 10.1021/acs.molpharmaceut.3c00102 |
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2023 Journal Article Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administrationIbrahim, Jibriil P., Butcher, Neville J., Kothapalli, Ashok, Subasic, Christopher N., Blanchfield, Joanne T., Whittaker, Andrew K., Whittaker, Michael R and Kaminskas, Lisa M. (2023). Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration. Expert Opinion on Drug Delivery, 20 (8), 1145-1155. doi: 10.1080/17425247.2023.2244881 |
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2023 Journal Article Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activitiesChoudhury, Chandra, McAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2023). Contrasting effects of temperature on human arylamine N-acetyltransferase and acetyl coenzyme A hydrolase activities. Biochemistry, 62 (14), 2093-2097. doi: 10.1021/acs.biochem.3c00113 |
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2023 Journal Article Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in ratsSubasic, Christopher N., Butcher, Neville J., Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (7), 3494-3504. doi: 10.1021/acs.molpharmaceut.3c00104 |
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2022 Journal Article Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosisMcAleese, Courtney E., Butcher, Neville J. and Minchin, Rodney F. (2022). Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis. Breast Cancer Research and Treatment, 195 (3), 223-236. doi: 10.1007/s10549-022-06668-3 |
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2022 Journal Article Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usageChoudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2022). Polymorphism in the human arylamine N-acetyltransferase 1 gene 3′-untranslated region determines polyadenylation signal usage. Biochemical Pharmacology, 200 115020, 115020. doi: 10.1016/j.bcp.2022.115020 |
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2021 Journal Article Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteinsSubasic, Christopher N., Ardana, Aditya, Chan, Linda J., Huang, Fei, Scoble, Judith A., Butcher, Neville J., Meagher, Laurence, Chiefari, John, Kaminskas, Lisa M. and Williams, Charlotte C. (2021). Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins. International Journal of Pharmaceutics, 608 121075, 121075. doi: 10.1016/j.ijpharm.2021.121075 |
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2021 Journal Article Hypoxia-mediated drug resistance in breast cancersMcAleese, Courtney E., Choudhury, Chandra, Butcher, Neville J. and Minchin, Rodney F. (2021). Hypoxia-mediated drug resistance in breast cancers. Cancer Letters, 502, 189-199. doi: 10.1016/j.canlet.2020.11.045 |
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2021 Journal Article Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicinWang, Lili, Butcher, Neville J, Minchin, Rodney F and Kaminskas, Lisa M (2021). Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin. Journal of Pharmaceutical Sciences, 110 (8), 3099-3101. doi: 10.1016/j.xphs.2021.05.009 |
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2020 Journal Article Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2Butcher, Neville J., Burow, Rachel and Minchin, Rodney F. (2020). Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2. Molecular Pharmacology, 98 (2), 88-95. doi: 10.1124/mol.119.119008 |
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2020 Journal Article Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and functionIdris, Misgana, Mitchell, Deanne J., Gordon, Richard, Sidharthan, Neelima P., Butcher, Neville J. and Minchin, Rodney F. (2020). Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function. Drug Metabolism and Disposition, 48 (5), 337-344. doi: 10.1124/dmd.119.089714 |
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2020 Journal Article Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αVLi, Pengcheng, Butcher, Neville J. and Minchin, Rodney F. (2020). Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV. Cell Adhesion and Migration, 14 (1), 1-11. doi: 10.1080/19336918.2019.1710015 |
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2019 Journal Article Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-αLi, Pengcheng, Butcher, Neville J. and Minchin, Rod (2019). Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α. Molecular Pharmacology, 96 (5), 573-579. doi: 10.1124/mol.119.117432 |
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2019 Journal Article Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complexWang, Lili, Minchin, Rodney F., Essebier, Patricia J. and Butcher, Neville J. (2019). Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex. International Journal of Biochemistry and Cell Biology, 110, 84-90. doi: 10.1016/j.biocel.2019.03.002 |
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2019 Journal Article A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in ratsKaminskas, Lisa M., Williams, Charlotte C., Leong, Nathania J., Chan, Linda J., Butcher, Neville J., Feeney, Orlagh M., Porter, Christopher J.H., Tyssen, David, Tachedjian, Gilda and Ascher, David B. (2019). A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats. European Journal of Pharmaceutics and Biopharmaceutics, 137, 218-226. doi: 10.1016/j.ejpb.2019.03.008 |
