Dr Neville Butcher
Dr

Neville Butcher

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Availability

Dr Neville Butcher is:
Available for supervision

Fields of research

Biological Sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences

Search Professor Neville Butcher’s works on UQ eSpace

66 works between 1996 and 2025
All (66) Journal Article (55) Book Chapter (4) Conference Publication (7)

21 - 40 of 66 works

2020

Journal Article

Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2

Butcher, Neville J., Burow, Rachel and Minchin, Rodney F. (2020). Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2. Molecular Pharmacology, 98 (2), 88-95. doi: 10.1124/mol.119.119008

Modulation of human arylamine N-acetyltransferase 1 activity by lysine acetylation: role of p300/CREB-binding protein and sirtuins 1 and 2

2020

Journal Article

Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function

Idris, Misgana, Mitchell, Deanne J., Gordon, Richard, Sidharthan, Neelima P., Butcher, Neville J. and Minchin, Rodney F. (2020). Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function. Drug Metabolism and Disposition, 48 (5), 337-344. doi: 10.1124/dmd.119.089714

Interaction of the brain-selective sulfotransferase SULT4A1 with other cytosolic sulfotransferases: effects on protein expression and function

2020

Journal Article

Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV

Li, Pengcheng, Butcher, Neville J. and Minchin, Rodney F. (2020). Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV. Cell Adhesion and Migration, 14 (1), 1-11. doi: 10.1080/19336918.2019.1710015

Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix metalloproteinases and integrin αV

2019

Journal Article

Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α

Li, Pengcheng, Butcher, Neville J. and Minchin, Rod (2019). Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α. Molecular Pharmacology, 96 (5), 573-579. doi: 10.1124/mol.119.117432

Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α

2019

Journal Article

Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex

Wang, Lili, Minchin, Rodney F., Essebier, Patricia J. and Butcher, Neville J. (2019). Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex. International Journal of Biochemistry and Cell Biology, 110, 84-90. doi: 10.1016/j.biocel.2019.03.002

Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex

2019

Journal Article

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Kaminskas, Lisa M., Williams, Charlotte C., Leong, Nathania J., Chan, Linda J., Butcher, Neville J., Feeney, Orlagh M., Porter, Christopher J.H., Tyssen, David, Tachedjian, Gilda and Ascher, David B. (2019). A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats. European Journal of Pharmaceutics and Biopharmaceutics, 137, 218-226. doi: 10.1016/j.ejpb.2019.03.008

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

2019

Journal Article

The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation

Idris, Misgana, Butcher, Neville J and Minchin, Rodney F (2019). The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation. Drug Metabolism and Disposition, 47 (3), 314-319. doi: 10.1124/dmd.118.085290

The MBNL/CELF splicing factors regulate cytosolic sulfotransferase 4A1 protein expression during cell differentiation

2019

Conference Publication

Regulation of MMP9 expression by human arylamine N-acetyltransferase (NAT1) via Hif-1a

Li, P., Minchin, R. F. and Butcher, N. (2019). Regulation of MMP9 expression by human arylamine N-acetyltransferase (NAT1) via Hif-1a. ESMO Breast Cancer, Berlin, Germany, 2-4 May 2019 . Amsterdam, Netherlands: Elsevier.

Regulation of MMP9 expression by human arylamine N-acetyltransferase (NAT1) via Hif-1a

2018

Journal Article

Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate

Minchin, Rodney F., Rosengren, K. Johan, Burow, Rachel and Butcher, Neville J. (2018). Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate. Biochemical Pharmacology, 158, 153-160. doi: 10.1016/j.bcp.2018.10.013

Allosteric regulation of arylamine N-acetyltransferase 1 by adenosine triphosphate

2018

Journal Article

Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance

Minchin, Rodney F. and Butcher, Neville J. (2018). Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance. BMC Genomics, 19 (1) 513, 513. doi: 10.1186/s12864-018-4894-4

Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance

2018

Journal Article

Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability

Wang, LiLi, Minchin, Rodney F and Butcher, Neville J (2018). Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability. PLoS One, 13 (3) e0193560, e0193560. doi: 10.1371/journal.pone.0193560

Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability

2018

Book Chapter

Human Arylamine N-Acetyltransferase Type 1

Butcher, Neville J., Li, Pengcheng, Wang, Lili and Minchin, Rodney F. (2018). Human Arylamine N-Acetyltransferase Type 1. Arylamine N-acetyltransferases in Health and Disease: From Pharmacogenetics to Drug Discovery and Diagnostics. (pp. 91-107) edited by Nicola Laurieri and Edith Sim. Singapore: World Scientific Publishing. doi: 10.1142/9789813232013_0004

Human Arylamine N-Acetyltransferase Type 1

2017

Journal Article

Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease

Butcher, N. J., Horne, M. K., Mellick, G. D., Fowler, C. J., Masters, C. L. and Minchin, R. F. (2017). Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease. Pharmacogenomics Journal, 18 (2), 209-214. doi: 10.1038/tpj.2017.4

Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease

2017

Journal Article

Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway

Witham, Katey L., Minchin, Rodney F. and Butcher, Neville J. (2017). Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway. Biochemical Pharmacology, 125, 93-100. doi: 10.1016/j.bcp.2016.11.015

Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway

2016

Journal Article

Drug delivery: unravelling the stealth effect

Butcher, Neville J., Mortimer, Gysell M. and Minchin, Rodney F. (2016). Drug delivery: unravelling the stealth effect. Nature Nanotechnology, 11 (4), 310-311. doi: 10.1038/nnano.2016.6

Drug delivery: unravelling the stealth effect

2015

Journal Article

The role of lysine100 in the binding of acetylcoenzyme A to human arylamine N-acetyltransferase 1: Implications for other acetyltransferases

Minchin, Rodney F and Butcher, Neville J (2015). The role of lysine100 in the binding of acetylcoenzyme A to human arylamine N-acetyltransferase 1: Implications for other acetyltransferases. Biochemical Pharmacology, 94 (3), 195-202. doi: 10.1016/j.bcp.2015.01.015

The role of lysine100 in the binding of acetylcoenzyme A to human arylamine N-acetyltransferase 1: Implications for other acetyltransferases

2015

Journal Article

Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines

Tiang, Jacky M., Butcher, Neville J. and Minchin, Rodney F. (2015). Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines. Cancer Medicine, 4 (4), 565-574. doi: 10.1002/cam4.415

Effects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines

2014

Journal Article

Expression of the orphan cytosolic sulfotransferase SULT4A1 and its major splice variant in human tissues and cells: dimerization, degradation and polyubiquitination

Sidharthan, Neelima P., Butcher, Neville J., Mitchell, Deanne J. and Minchin, Rodney F. (2014). Expression of the orphan cytosolic sulfotransferase SULT4A1 and its major splice variant in human tissues and cells: dimerization, degradation and polyubiquitination. PLoS One, 9 (7) e101520, e101520.1-e101520.8. doi: 10.1371/journal.pone.0101520

Expression of the orphan cytosolic sulfotransferase SULT4A1 and its major splice variant in human tissues and cells: dimerization, degradation and polyubiquitination

2014

Journal Article

Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro

Stephenson, Rachel, Varamini, Pegah, Butcher, Neville, Minchin, Rodney and Toth, Istvan (2014). Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro. Nanomedicine: Nanotechnology, Biology and Medicine, 10 (8), 1799-1808. doi: 10.1016/j.nano.2014.06.015

Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro

2014

Journal Article

Cryptic epitopes of albumin determine mononuclear phagocyte system clearance of nanomaterials

Mortimer, Gysell M., Butcher, Neville J., Musumeci, Anthony W., Deng, Zhou J., Martin, Darren J. and Minchin, Rodney F. (2014). Cryptic epitopes of albumin determine mononuclear phagocyte system clearance of nanomaterials. ACS Nano, 8 (4), 3357-3366. doi: 10.1021/nn405830g

Cryptic epitopes of albumin determine mononuclear phagocyte system clearance of nanomaterials

Past funding

  • 2016 - 2019
    The pharmacology of sulfotransferase 4A1
    NHMRC Project Grant
    Open grant
  • 2015 - 2017
    Role of sirtuins in the regulation of the carcinogen metabolising arylamine N-acetyltransferases
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Role of the drug metabolising enzyme arylamine N-acetyltransferase 1 in breast cancer
    NHMRC Project Grant
    Open grant
  • 2011 - 2013
    ResTeach 2011 0.1 FTE School of Biomedical Sciences
    UQ ResTeach
    Open grant
  • 2009 - 2012
    Pharmacological Targeting of Arylamine N-Acetyltransferase I
    NHMRC Project Grant
    Open grant

Availability

Dr Neville Butcher is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Charaterisation of ion channels as pattern recognition receptors for acidosis and potential anti-inflammatory targets.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Developing novel acid-sensing ion channel inhibitors as neuroprotective leads and diagnostic agents for multiple sclerosis.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Developing novel acid-sensing ion channel inhibitors as neuroprotective leads and diagnostic agents for multiple sclerosis.

    Associate Advisor

    Other advisors: Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Understanding the role acid-sensing ion channels in disease progression and pain associated with neuroinflammatory conditions.

    Associate Advisor

    Other advisors: Emeritus Professor Maree Smith, Dr Nemat Khan, Dr Lachlan Rash

  • Doctor Philosophy

    Inhalable nanoparticle-based gene delivery system for cystic fibrosis

    Associate Advisor

    Other advisors: Professor Kristofer Thurecht, Associate Professor Lisa Kaminskas

Completed supervision

Enquiries

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