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2024 Journal Article A PEGylated liposomal formulation of prochlorperazine that limits brain exposure but retains dynamin II activity: A potential adjuvant therapy for cancer patients receiving chemotherapeutic mAbsSubasic, Christopher N., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2024). A PEGylated liposomal formulation of prochlorperazine that limits brain exposure but retains dynamin II activity: A potential adjuvant therapy for cancer patients receiving chemotherapeutic mAbs. Nanomedicine: Nanotechnology, Biology and Medicine, 56 102733, 1-8. doi: 10.1016/j.nano.2024.102733 |
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2024 Journal Article Hydrogenated soy phosphatidylcholine liposomes stimulate differential expression of chemokines and cytokines by rat alveolar macrophages in vitroIbrahim, Jibriil P., Dao, Nam, Haque, Shadabul, Phipps, Simon, Whittaker, Michael R. and Kaminskas, Lisa M. (2024). Hydrogenated soy phosphatidylcholine liposomes stimulate differential expression of chemokines and cytokines by rat alveolar macrophages in vitro. Journal of Pharmaceutical Sciences, 113 (5), 1395-1400. doi: 10.1016/j.xphs.2024.03.001 |
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2024 Journal Article Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platformsKaminskas, Lisa M., Butcher, Neville J., Subasic, Christopher N., Kothapalli, Ashok, Haque, Shadabul, Grace, James L., Morsdorf, Alexander, Blanchfield, Joanne T., Whittaker, Andrew K., Quinn, John F. and Whittaker, Michael R. (2024). Lipidated brush-PEG polymers as low molecular weight pulmonary drug delivery platforms. Expert Opinion On Drug Delivery, 21 (1), 151-167. doi: 10.1080/17425247.2024.2305116 |
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2024 Journal Article Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinityEdiriweera, Gayathri R., Butcher, Neville J., Kothapalli, Ashok, Zhao, Jiacheng, Blanchfield, Joanne T., Subasic, Christopher N., Grace, James L., Fu, Changkui, Tan, Xiao, Quinn, John F., Ascher, David B., Whittaker, Michael R., Whittaker, Andrew K. and Kaminskas, Lisa M. (2024). Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity. Biomaterials Science, 12 (11), 2978-2992. doi: 10.1039/d3bm02020g |
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2024 Journal Article The emergence of inhalable RNA therapeutics and challenges faced - where to from here?Haque, Shadabul and Kaminskas, Lisa M. (2024). The emergence of inhalable RNA therapeutics and challenges faced - where to from here?. Nanomedicine, 20 (3), 1-3. doi: 10.1080/17435889.2024.2429368 |
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2023 Journal Article Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in ratsSubasic, Christopher N., Butcher, Neville J., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (9), 4468-4477. doi: 10.1021/acs.molpharmaceut.3c00102 |
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2023 Journal Article Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administrationIbrahim, Jibriil P., Butcher, Neville J., Kothapalli, Ashok, Subasic, Christopher N., Blanchfield, Joanne T., Whittaker, Andrew K., Whittaker, Michael R and Kaminskas, Lisa M. (2023). Utilization of endogenous albumin trafficking pathways in the lungs has potential to modestly increase the lung interstitial access and absorption of drug delivery systems after inhaled administration. Expert Opinion on Drug Delivery, 20 (8), 1145-1155. doi: 10.1080/17425247.2023.2244881 |
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2023 Journal Article Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in ratsSubasic, Christopher N., Butcher, Neville J., Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent production of anti-PEG IgM after intramuscular PEGylated-hydrogenated soy phosphatidylcholine liposomes, but not lipid nanoparticle formulations of DNA, correlates with the plasma clearance of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (7), 3494-3504. doi: 10.1021/acs.molpharmaceut.3c00104 |
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2023 Journal Article Demonstrating a link between diet, gut microbiota and brain: 14C radioactivity identified in the brain following gut microbial fermentation of 14C-radiolabeled tyrosine in a pig modelMurray, Margaret, Barlow, Christopher K., Blundell, Scott, Buecking, Mark, Gibbon, Anne, Goeckener, Bernd, Kaminskas, Lisa M., Leitner, Patricia, Selby-Pham, Sophie, Sinclair, Andrew, Waktola, Habtewold D., Williamson, Gary and Bennett, Louise E. (2023). Demonstrating a link between diet, gut microbiota and brain: 14C radioactivity identified in the brain following gut microbial fermentation of 14C-radiolabeled tyrosine in a pig model. Frontiers in Nutrition, 10 1127729, 1-14. doi: 10.3389/fnut.2023.1127729 |
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2022 Journal Article Liposomes are poorly absorbed via lung lymph after inhaled administration in sheepIbrahim, Jibriil P., Haque, Shadabul, Bischof, Robert J., Whittaker, Andrew K., Whittaker, Michael R. and Kaminskas, Lisa M. (2022). Liposomes are poorly absorbed via lung lymph after inhaled administration in sheep. Frontiers in Pharmacology, 13 880448, 1-9. doi: 10.3389/fphar.2022.880448 |
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2022 Journal Article Development of a hyperbranched polymer-based methotrexate nanomedicine for rheumatoid arthritisMarasini, Nirmal, Er, Gerald, Fu, Changkui, Subasic, Christopher N., Ibrahim, Jibriil, Skwarczynski, Mariusz, Toth, Istvan, Whittaker, Andrew K. and Kaminskas, Lisa M. (2022). Development of a hyperbranched polymer-based methotrexate nanomedicine for rheumatoid arthritis. Acta Biomaterialia, 142, 298-307. doi: 10.1016/j.actbio.2022.01.054 |
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2021 Journal Article Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteinsSubasic, Christopher N., Ardana, Aditya, Chan, Linda J., Huang, Fei, Scoble, Judith A., Butcher, Neville J., Meagher, Laurence, Chiefari, John, Kaminskas, Lisa M. and Williams, Charlotte C. (2021). Poly(HPMA-co-NIPAM) copolymer as an alternative to polyethylene glycol-based pharmacokinetic modulation of therapeutic proteins. International Journal of Pharmaceutics, 608 121075, 121075. doi: 10.1016/j.ijpharm.2021.121075 |
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2021 Journal Article The pharmacokinetics of PEGylated liposomal doxorubicin are not significantly affected by sex in rats or humans, but may be affected by immune dysfunctionSubasic, Christopher N., Kuilamu, Esther, Cowin, Gary, Minchin, Rodney F. and Kaminskas, Lisa M. (2021). The pharmacokinetics of PEGylated liposomal doxorubicin are not significantly affected by sex in rats or humans, but may be affected by immune dysfunction. Journal of Controlled Release, 337, 71-80. doi: 10.1016/j.jconrel.2021.07.006 |
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2021 Journal Article Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cellsDao, Nam V., Ercole, Francesca, Li, Yuhuan, Davis, Thomas P., Kaminskas, Lisa M., Sloan, Erica K., Quinn, John F. and Whittaker, Michael R. (2021). Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells. Journal of Materials Chemistry B, 9 (37), 7805-7820. doi: 10.1039/d1tb00812a |
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2021 Journal Article Recent advances in nano/microparticle-based oral vaccinesLi, Mengdie, Kaminskas, Lisa M. and Marasini, Nirmal (2021). Recent advances in nano/microparticle-based oral vaccines. Journal of Pharmaceutical Investigation, 51 (4), 1-14. doi: 10.1007/s40005-021-00537-9 |
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2021 Journal Article Depolymerization of hyaluronan using PEGylated human recombinant hyaluronidase promotes nanoparticle tumor penetrationBrundel, Daniel H.S., Feeney, Orlagh M., Nowell, Cameron J., Suys, Estelle J.A., Gracia, Gracia, Kaminskas, Lisa M., McIntosh, Michelle M., Kang, David W. and Porter, Christopher J.H. (2021). Depolymerization of hyaluronan using PEGylated human recombinant hyaluronidase promotes nanoparticle tumor penetration. Nanomedicine, 16 (4), 275-292. doi: 10.2217/nnm-2020-0433 |
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2021 Journal Article Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture modelDao, Nam V., Ercole, Francesca, Urquhart, Matthew C., Kaminskas, Lisa M., Nowell, Cameron J., Davis, Thomas P., Sloan, Erica K., Whittaker, Michael R. and Quinn, John F. (2021). Trisulfide linked cholesteryl PEG conjugate attenuates intracellular ROS and collagen-1 production in a breast cancer co-culture model. Biomaterials Science, 9 (3), 835-846. doi: 10.1039/d0bm01544j |
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2021 Journal Article Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicinWang, Lili, Butcher, Neville J, Minchin, Rodney F and Kaminskas, Lisa M (2021). Monocytes do not contribute to sex differences seen in the pharmacokinetics of pegylated liposomal doxorubicin. Journal of Pharmaceutical Sciences, 110 (8), 3099-3101. doi: 10.1016/j.xphs.2021.05.009 |
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2020 Journal Article Trisulfide-bearing PEG brush polymers donate hydrogen sulfide and ameliorate cellular oxidative stressDao, Nam V., Ercole, Francesca, Kaminskas, Lisa M., Davis, Thomas P., Sloan, Erica K., Whittaker, Michael R. and Quinn, John F. (2020). Trisulfide-bearing PEG brush polymers donate hydrogen sulfide and ameliorate cellular oxidative stress. Biomacromolecules, 21 (12), 5292-5305. doi: 10.1021/acs.biomac.0c01347 |
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2020 Journal Article The impact of polymer size and cleavability on the intravenous pharmacokinetics of PEG-based hyperbranched polymers in ratsMarasini, Nirmal, Fu, Changkui, Fletcher, Nicholas L., Subasic, Christopher, Er, Gerald, Mardon, Karine, Thurecht, Kristofer J., Whittaker, Andrew K. and Kaminskas, Lisa M. (2020). The impact of polymer size and cleavability on the intravenous pharmacokinetics of PEG-based hyperbranched polymers in rats. Nanomaterials, 10 (12) 2452, 1-16. doi: 10.3390/nano10122452 |
