Dr Hao Song
Dr

Hao Song

Email: 
Phone: 
+61 7 334 63815

Availability

Dr Hao Song is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Hao Song’s works on UQ eSpace

88 works between 2014 and 2024
All (88) Journal Article (87) Other Outputs (1)

61 - 80 of 88 works

2018

Journal Article

Hybrid nanoreactors enable an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy

Yang, Yannan, Tang, Jie, Abbaraju, Prasanna Lakshmi, Jambhrunkar, Manasi, Song, Hao, Zhang, Min, Lei, Chang, Fu, Jianye, Gu, Zhengying, Liu, Yang and Yu, Chengzhong (2018). Hybrid nanoreactors enable an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy. Angewandte Chemie, 57 (36), 11764-11769. doi: 10.1002/anie.201807595

Hybrid nanoreactors enable an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy

2018

Other Outputs

Engineered silica nanoparticles for efficient biomolecules delivery

Song, Hao (2018). Engineered silica nanoparticles for efficient biomolecules delivery. PhD Thesis, Aust Institute for Bioengineering & Nanotechnology, The University of Queensland. doi: 10.14264/uql.2018.130

Engineered silica nanoparticles for efficient biomolecules delivery

2018

Journal Article

Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance

Wang, Yue, Song, Hao, Yu, Meihua, Xu, Chun, Liu, Yang, Tang, Jie, Yang, Yannan and Yu, Chengzhong (2018). Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance. Journal of Materials Chemistry B, 6 (24), 4089-4095. doi: 10.1039/c8tb00544c

Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance

2018

Journal Article

Oxidative dissolution of resoles: a versatile approach to intricate nanostructures

Zhang, Min, Song, Hao, Yang, Yannan, Huang, Xiaodan, Liu, Yang, Liu, Chao and Yu, Chengzhong (2018). Oxidative dissolution of resoles: a versatile approach to intricate nanostructures. Angewandte Chemie - International Edition, 56 (3), 654-658. doi: 10.1002/anie.201709591

Oxidative dissolution of resoles: a versatile approach to intricate nanostructures

2017

Journal Article

Mg(OH)(2)-MgO@reduced graphene oxide nanocomposites: the roles of composition and nanostructure in arsenite sorption

Purwajanti, Swasmi, Huang, Xiaodan, Liu, Yang, Yang, Yannan, Noonan, Owen, Song, Hao, Zhang, Jun, Zhang, Jing, Fu, Jianye, Liang, Changhao and Yu, Chengzhong (2017). Mg(OH)(2)-MgO@reduced graphene oxide nanocomposites: the roles of composition and nanostructure in arsenite sorption. Journal of Materials Chemistry a, 5 (46), 24484-24492. doi: 10.1039/c7ta07629k

Mg(OH)(2)-MgO@reduced graphene oxide nanocomposites: the roles of composition and nanostructure in arsenite sorption

2017

Journal Article

Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks

Liu, Chao, Huang, Xiaodan, Wang, Jing, Song, Hao, Yang, Yannan, Liu, Yang, Li, Jiansheng, Wang, Lianjun and Yu, Chengzhong (2017). Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks. Advanced Functional Materials, 28 (6) 1705253, 1705253. doi: 10.1002/adfm.201705253

Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks

2017

Journal Article

Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal-support interaction

Jiao, Jinqing, Fu, Jianye, Wei, Yuechang, Zhao, Zhen, Duan, Aijun, Xu, Chunming, Li, Jianmei, Song, Hao, Zheng, Peng, Wang, Xilong, Yang, Yannan and Liu, Yang (2017). Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal-support interaction. Journal of Catalysis, 356, 269-282. doi: 10.1016/j.jcat.2017.10.003

Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal-support interaction

2017

Journal Article

Plasmid DNA Delivery: Nanotopography Matters

Song, Hao, Yu, Meihua, Lu, Yao, Gu, Zhengying, Yang, Yannan, Zhang, Min, Fu, Jianye and Yu, Chengzhong (2017). Plasmid DNA Delivery: Nanotopography Matters. Journal of the American Chemical Society, 139 (50), 18247-18254. doi: 10.1021/jacs.7b08974

Plasmid DNA Delivery: Nanotopography Matters

2017

Journal Article

Single-layered mesoporous carbon sandwiched graphene nanosheets for high performance ionic liquid supercapacitors

Liu, Yang, Zhang, Hongwei, Song, Hao, Noonan, Owen, Lang, Changhao, Huang, Xiaodan and Yu, Chengzhong (2017). Single-layered mesoporous carbon sandwiched graphene nanosheets for high performance ionic liquid supercapacitors. Journal of Physical Chemistry C, 121 (43), 23947-23954. doi: 10.1021/acs.jpcc.7b08777

Single-layered mesoporous carbon sandwiched graphene nanosheets for high performance ionic liquid supercapacitors

2017

Journal Article

Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy

Xu, Chun, Lei, Chang, Huang, Lili, Zhang, Jun, Zhang, Hongwei, Song, Hao, Yu, Meihua, Wu, Yeda, Chen, Chen and Yu, Chengzhong (2017). Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy. Chemistry of Materials, 29 (18), 7725-7732. doi: 10.1021/acs.chemmater.7b01804

Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy

2017

Journal Article

Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells

Abbaraju, Prasanna Lakshmi, Meka, Anand Kumar, Song, Hao, Yang, Yannan, Jambhrunkar, Manasi, Zhang, Jun, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2017). Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells. Journal of the American Chemical Society, 139 (18), 6321-6328. doi: 10.1021/jacs.6b12622

Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells

2017

Journal Article

Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis

Kalantari, Mohammad, Yu, Meihua, Yang, Yannan, Strounina, Ekaterina, Gu, Zhengying, Huang, Xiaodan, Zhang, Jun, Song, Hao and Yu, Chengzhong (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10 (2), 605-617. doi: 10.1007/s12274-016-1320-6

Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis

2017

Journal Article

Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment

Kalantari, Mohammad, Yu, Meihua, Noonan, Owen, Song, Hao, Xu, Chun, Huang, Xiaodan, Xiang, Feixiang, Wang, Xiaolin and Yu, Chengzhong (2017). Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment. Chemosphere, 166, 109-117. doi: 10.1016/j.chemosphere.2016.09.083

Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment

2016

Journal Article

Encapsulation of selenium sulfide in double-layered hollow carbon spheres as advanced electrode material for lithium storage

Zhang, Hongwei, Zhou, Liang, Huang, Xiaodan, Song, Hao and Yu, Chengzhong (2016). Encapsulation of selenium sulfide in double-layered hollow carbon spheres as advanced electrode material for lithium storage. Nano Research, 9 (12), 3725-3734. doi: 10.1007/s12274-016-1243-2

Encapsulation of selenium sulfide in double-layered hollow carbon spheres as advanced electrode material for lithium storage

2016

Journal Article

Hollow mesoporous carbon nanocarriers for vancomycin delivery: understanding the structure-release relationship for prolonged antibacterial performance

Nor, Yusilawati Ahmad, Zhang, Hongwei, Purwajanti, Swasmi, Song, Hao, Meka, Anand Kumar, Wang, Yue, Mitter, Neena, Mahony, Donna and Yu, Chengzhong (2016). Hollow mesoporous carbon nanocarriers for vancomycin delivery: understanding the structure-release relationship for prolonged antibacterial performance. Journal of Materials Chemistry B, 4 (43), 7014-7021. doi: 10.1039/c6tb01778a

Hollow mesoporous carbon nanocarriers for vancomycin delivery: understanding the structure-release relationship for prolonged antibacterial performance

2016

Journal Article

Mesoporous magnesium oxide hollow spheres as superior arsenite adsorbent: synthesis and adsorption behavior

Purwajanti, Swasmi, Zhang, Hongwei, Huang, Xiaodan, Song, Hao, Yang, Yannan, Zhang, Jun, Niu, Yuting, Meka, Anand Kumar, Noonan, Owen and Yu, Chengzhong (2016). Mesoporous magnesium oxide hollow spheres as superior arsenite adsorbent: synthesis and adsorption behavior. ACS Applied Materials and Interfaces, 8 (38), 25306-25312. doi: 10.1021/acsami.6b08322

Mesoporous magnesium oxide hollow spheres as superior arsenite adsorbent: synthesis and adsorption behavior

2016

Journal Article

In situ Stöber templating: facile synthesis of hollow mesoporous carbon spheres from silica-polymer composites for ultra-high level in-cavity adsorption

Noonan, Owen, Zhang, Hongwei, Song, Hao, Xu, Chun, Huang, Xiaodan and Yu, Chengzhong (2016). In situ Stöber templating: facile synthesis of hollow mesoporous carbon spheres from silica-polymer composites for ultra-high level in-cavity adsorption. Journal of Materials Chemistry A, 4 (23), 9063-9071. doi: 10.1039/c6ta02265k

In situ Stöber templating: facile synthesis of hollow mesoporous carbon spheres from silica-polymer composites for ultra-high level in-cavity adsorption

2016

Journal Article

Silica nanopollens enhance adhesion for long-term bacterial inhibition

Song, Hao, Ahmad Nor, Yusilawati, Yu, Meihua, Yang, Yannan, Zhang, Jun, Zhang, Hongwei, Xu, Chun, Mitter, Neena and Yu, Chengzhong (2016). Silica nanopollens enhance adhesion for long-term bacterial inhibition. Journal of the Americal Chemical Society, 138 (20), 6455-6462. doi: 10.1021/jacs.6b00243

Silica nanopollens enhance adhesion for long-term bacterial inhibition

2016

Journal Article

Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery

Wang, Yue, Nor, Yusilawati Ahmad, Song, Hao, Yang, Yannan, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4 (15), 2646-2653. doi: 10.1039/c6tb00053c

Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery

2016

Journal Article

Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient

Yang, Yannan, Bernardi, Stefano, Song, Hao, Zhang, Jun, Yu, Meihua, Reid, James C., Strounina, Ekaterina, Searles, Debra J. and Yu, Chengzhong (2016). Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient. Chemistry of Materials, 28 (3), 704-707. doi: 10.1021/acs.chemmater.5b03963

Anion assisted synthesis of large pore hollow dendritic mesoporous organosilica nanoparticles: understanding the composition gradient

Current funding

  • 2026 - 2030
    Harnessing Nanotechnology to Develop Next-Generation mRNA Oral Vaccines
    NHMRC Investigator Grants
    Open grant
  • 2023 - 2024
    Nanotechnology enabled long-acting antiretroviral therapy for improved HIV treatment adherence (ACH4 grant administered by the Westmead Institute for Medical Research)
    Australian Centre for HIV and Hepatitis Virology Research (ACH4)
    Open grant
  • 2023 - 2026
    Designer Nanoparticles Enable mRNA Protein Factories
    ARC Linkage Projects
    Open grant
  • 2021 - 2025
    Development of a market relevant DNA nano-vaccine platform
    ARC Linkage Projects
    Open grant
  • 2021 - 2025
    A Long-Lasting Oral Drug Delivery System Using Spiky Silica Nanoparticles
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2023
    Bio-inspired Nanoparticles for Next-generation Shelf-stable mRNA Vaccines
    UQ Foundation Research Excellence Awards
    Open grant
  • 2021 - 2022
    Developing a thermal-stable nanoparticle-based oral vaccine: towards commercial reality
    UQ Knowledge Exchange & Translation Fund
    Open grant
  • 2021 - 2024
    Engineering nanoparticles with enhanced adhesion at the nano-bio interfaces
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2020 - 2021
    COVID-19 DNA vaccine in vivo study using NUVEC nanoparticles
    UniQuest Pty Ltd
    Open grant
  • 2019 - 2021
    N4 Pharma - repeat and extension of in vivo DNA vaccine study
    UniQuest Pty Ltd
    Open grant
  • 2019 - 2020
    PEI Modification of CPI-NPs - compare PEI suppliers
    UniQuest Pty Ltd
    Open grant
  • 2019
    Multi-Scale Engineered Nano-Adjuvants for DNA Vaccine
    UQ Early Career Researcher
    Open grant
  • 2018
    To attend 2018 MRS Fall Meeting and Exhibit, Boston, USA, 23 November 2018 - 01 December 2018
    Ian Potter Foundation
    Open grant

Availability

Dr Hao Song is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • A nanotechnology for long-lasting oral drug delivery.

    Medication adherence is required for the effectiveness of all pharmacotherapies, especially for long-term treatment of chronic illness and infectious diseases such as malaria, diabetes, and HIV. However, intensive dosage regimens with a high pill burden are associated with a low adherence rate, leading to compromised or even failure of therapies. My project aims to realize the ideal of ‘pillbox in a capsule’, i.e. taking a single tablet that will provide sustained drug release over several days, by developing a long-lasting oral drug delivery platform with prolonged gastrointestinal transit time. Inspired by bio-adhesive natural systems, where spiky surfaces enable strong adhesion, this project will engineer silica particles with a spiky morphology as well as their assembled medical devices as oral drug delivery vehicles, and their interactions at the bio-interfaces in the gastrointestinal environment will be investigated in detail. On completion, this project will produce guidelines for the rational design of novel oral drug delivery systems, and new potential clinical strategies for simplified oral medications to improve medication adherence and patient outcomes.

  • Virus-mimicking nanoparticles for DNA vaccine

    DNA vaccine, as the third generation vaccine technology, representing the latest biotechnological breakthrough in vaccine development. Compared to conventional recombinant vaccines usually only stimulating the antibody responses, DNA vaccine show advantages in evoking both cellular and humoral immunity to fulfill the demand in combating chronic infectious diseases. Moreover, the cost-effectiveness and fast speed of production make DNA vaccine an ideal strategy to deal with outbreaks such as SARS-COV-2 and H5N1 for the sake of both public and animal healthcare. To enable a successful DNA vaccine technology, it is critical to develop efficient gene vectors to transport and regulate the DNA molecules to be highly expressed in target cells. Mimicking the morphology of the virus, this project aims to fabricate a series of virus-like silica nanoparticles with tailored physicochemical features for plasmid DNA delivery and investigate their gene translation and vaccine performance. The completion of this project will provide fundamental understandings of the impact of designer particle nanostructure/chemistry on DNA transfection and vaccine immunogenicity.

  • Nature-inspired spiky nanomaterials probed at the bio-nano interfaces

    The intriguing nature systems have inspired remarkable advances in the development of functional nanomaterials for biomedical applications. Nature creations such as pollen grains and virus with spiky topological features at various length scales enable multivalent interactions at bio-interfaces, and typically exhibit intriguing surface adhesive property. This project aims to apply this nature-derived principle to engineer nanoparticles for enhanced intracellular delivery of biomolecules. Nanomaterials with functional compositions and tailored spiky nanostructures will be fabricated. Their cellular internalization process and biomolecules delivery efficiency will be evaluated. On completion of this project, a versatile and functional drug delivery platform will be established and an in-depth understanding of the spiky nanoparticle-cell interaction will be revealed.

  • Antibiotic-free antibacterial nanotechnology

    The overuse of antibiotics leads to ever-increasing antibiotic resistance, posing a severe threat to human health. Recent advances in nanotechnology provide new opportunities to address the challenges in bacterial infection by killing germs without using antibiotics. This project aims to develop antibiotic-free antibacterial formulations enabled by advanced nanomaterials. Functional nanomaterials with intrinsic or light-mediated bactericidal properties will be fabricated to enable efficient pathogen killing. Meanwhile, porous nanoparticles will also be engineered to serve as vehicles for the delivery of natural antibacterial compounds, formulating Pickering emulsion for stable and sparable antibacterial nano-agents. On the completion of this project, nano-formulations showing potent antibacterial property and good safety will be provided, and their antibacterial mechanisms, as well as the structure-performance relationship, will be revealed.

Supervision history

Current supervision

  • Doctor Philosophy

    Engineering Spiky Nanoparticles Probed at the Nano-Bio Interfaces

    Principal Advisor

    Other advisors: Professor Michael Yu

  • Doctor Philosophy

    Biomimetic Nanoparticles for Efficient Vaccine Delivery

    Principal Advisor

  • Doctor Philosophy

    clinically-oriented synergized immunotherapy strategies for breast cancer

    Principal Advisor

  • Doctor Philosophy

    Synthesis and applications of non-viral gene vectors

    Associate Advisor

    Other advisors: Professor Michael Yu

  • Doctor Philosophy

    Multifunctional hybrid mesoporous silica nanoparticles for stimuli-responsive delivery of antimicrobial agents

    Associate Advisor

    Other advisors: Professor Michael Yu

  • Doctor Philosophy

    Engineering encapsulation technology for enzyme immobilization

    Associate Advisor

  • Doctor Philosophy

    Development of a market relevant DNA nano-vaccine platform

    Associate Advisor

    Other advisors: Professor Michael Yu

Completed supervision

Enquiries

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