Overview
Availability
- Dr Hao Song is:
- Available for supervision
- Media expert
Qualifications
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Hao Song’s works on UQ eSpace
2018
Journal Article
Superhydrophobic dendritic mesoporous organosilica nano-particles with ultrahigh-content of gradient organic moieties
Kalantari, Mohammad, Liu, Yang, Strounina, Ekaterina, Yang, Yannan, Song, Hao and Yu, Chengzhong (2018). Superhydrophobic dendritic mesoporous organosilica nano-particles with ultrahigh-content of gradient organic moieties. Journal of Materials Chemistry A, 6 (36), 17579-17586. doi: 10.1039/c8ta06268d
2018
Journal Article
Kinetically controlled dendritic mesoporous silica nanoparticles: from dahlia- to pomegranate-like structures by micelle filling
Wang, Yue, Song, Hao, Yang, Yannan, Liu, Yang, Tang, Jie and Yu, Chengzhong (2018). Kinetically controlled dendritic mesoporous silica nanoparticles: from dahlia- to pomegranate-like structures by micelle filling. Chemistry of Materials, 30 (16) acs.chemmater.8b02712, 5770-5776. doi: 10.1021/acs.chemmater.8b02712
2018
Journal Article
Hybrid nanoreactors: enabling an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy
Yang, Yannan, Tang, Jie, Abbaraju, Prasanna Lakshmi, Jambhrunkar, Manasi, Song, Hao, Zhang, Min, Lei, Chang, Fu, Jianye, Gu, Zhengying, Liu, Yang and Yu, Chengzhong (2018). Hybrid nanoreactors: enabling an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy. Angewandte Chemie, 130 (36), 11938-11943. doi: 10.1002/ange.201807595
2018
Journal Article
Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and Co-delivery platform for enhanced cancer immunotherapy
Lu, Yao, Yang, Yannan, Gu, Zhengying, Zhang, Jun, Song, Hao, Xiang, Guangya and Yu, Chengzhong (2018). Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and Co-delivery platform for enhanced cancer immunotherapy. Biomaterials, 175, 82-92. doi: 10.1016/j.biomaterials.2018.05.025
2018
Journal Article
Hybrid nanoreactors enable an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy
Yang, Yannan, Tang, Jie, Abbaraju, Prasanna Lakshmi, Jambhrunkar, Manasi, Song, Hao, Zhang, Min, Lei, Chang, Fu, Jianye, Gu, Zhengying, Liu, Yang and Yu, Chengzhong (2018). Hybrid nanoreactors enable an off-the-shelf strategy for concurrently enhanced chemo-immunotherapy. Angewandte Chemie, 57 (36), 11764-11769. doi: 10.1002/anie.201807595
2018
Other Outputs
Engineered silica nanoparticles for efficient biomolecules delivery
Song, Hao (2018). Engineered silica nanoparticles for efficient biomolecules delivery. PhD Thesis, Aust Institute for Bioengineering & Nanotechnology, The University of Queensland. doi: 10.14264/uql.2018.130
2018
Conference Publication
Effect of Limited Aperture Size on a Retro-reflected Communication Link Between a Ground Station and a UAV using Multiplexing of Orbital-Angular-Momentum Beams
Li, Long, Zhang, Runzhou, Liao, Peicheng, Song, Hao, Zou, Kaiheng, Xie, Guodong, Zhao, Zhe, Liu, Cong, Song, Haoqian, Pang, Kai, Labroille, Guillaume, Jian, Pu, Starodubov, Dmitry, Lynn, Brittany, Bock, Robert, Tur, Moshe and Willner, Alan E. (2018). Effect of Limited Aperture Size on a Retro-reflected Communication Link Between a Ground Station and a UAV using Multiplexing of Orbital-Angular-Momentum Beams. Optical Fiber Communications Conference and Exposition (OFC), San Diego Ca, Mar 11-15, 2018. NEW YORK: IEEE.
2018
Journal Article
Oxidative dissolution of resoles: a versatile approach to intricate nanostructures
Zhang, Min, Song, Hao, Yang, Yannan, Huang, Xiaodan, Liu, Yang, Liu, Chao and Yu, Chengzhong (2018). Oxidative dissolution of resoles: a versatile approach to intricate nanostructures. Angewandte Chemie - International Edition, 56 (3), 654-658. doi: 10.1002/anie.201709591
2018
Journal Article
Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance
Wang, Yue, Song, Hao, Yu, Meihua, Xu, Chun, Liu, Yang, Tang, Jie, Yang, Yannan and Yu, Chengzhong (2018). Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance. Journal of Materials Chemistry B, 6 (24), 4089-4095. doi: 10.1039/c8tb00544c
2017
Journal Article
Mg(OH)(2)-MgO@reduced graphene oxide nanocomposites: the roles of composition and nanostructure in arsenite sorption
Purwajanti, Swasmi, Huang, Xiaodan, Liu, Yang, Yang, Yannan, Noonan, Owen, Song, Hao, Zhang, Jun, Zhang, Jing, Fu, Jianye, Liang, Changhao and Yu, Chengzhong (2017). Mg(OH)(2)-MgO@reduced graphene oxide nanocomposites: the roles of composition and nanostructure in arsenite sorption. Journal of Materials Chemistry a, 5 (46), 24484-24492. doi: 10.1039/c7ta07629k
2017
Journal Article
Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks
Liu, Chao, Huang, Xiaodan, Wang, Jing, Song, Hao, Yang, Yannan, Liu, Yang, Li, Jiansheng, Wang, Lianjun and Yu, Chengzhong (2017). Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks. Advanced Functional Materials, 28 (6) 1705253, 1705253. doi: 10.1002/adfm.201705253
2017
Journal Article
Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal-support interaction
Jiao, Jinqing, Fu, Jianye, Wei, Yuechang, Zhao, Zhen, Duan, Aijun, Xu, Chunming, Li, Jianmei, Song, Hao, Zheng, Peng, Wang, Xilong, Yang, Yannan and Liu, Yang (2017). Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal-support interaction. Journal of Catalysis, 356, 269-282. doi: 10.1016/j.jcat.2017.10.003
2017
Journal Article
Plasmid DNA Delivery: Nanotopography Matters
Song, Hao, Yu, Meihua, Lu, Yao, Gu, Zhengying, Yang, Yannan, Zhang, Min, Fu, Jianye and Yu, Chengzhong (2017). Plasmid DNA Delivery: Nanotopography Matters. Journal of the American Chemical Society, 139 (50), 18247-18254. doi: 10.1021/jacs.7b08974
2017
Journal Article
Single-layered mesoporous carbon sandwiched graphene nanosheets for high performance ionic liquid supercapacitors
Liu, Yang, Zhang, Hongwei, Song, Hao, Noonan, Owen, Lang, Changhao, Huang, Xiaodan and Yu, Chengzhong (2017). Single-layered mesoporous carbon sandwiched graphene nanosheets for high performance ionic liquid supercapacitors. Journal of Physical Chemistry C, 121 (43), 23947-23954. doi: 10.1021/acs.jpcc.7b08777
2017
Journal Article
Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy
Xu, Chun, Lei, Chang, Huang, Lili, Zhang, Jun, Zhang, Hongwei, Song, Hao, Yu, Meihua, Wu, Yeda, Chen, Chen and Yu, Chengzhong (2017). Glucose-responsive nanosystem mimicking the physiological insulin secretion via an enzyme-polymer layer-by-layer coating strategy. Chemistry of Materials, 29 (18), 7725-7732. doi: 10.1021/acs.chemmater.7b01804
2017
Journal Article
Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells
Abbaraju, Prasanna Lakshmi, Meka, Anand Kumar, Song, Hao, Yang, Yannan, Jambhrunkar, Manasi, Zhang, Jun, Xu, Chun, Yu, Meihua and Yu, Chengzhong (2017). Asymmetric silica nanoparticles with tunable head-tail structures enhance hemocompatibility and maturation of immune cells. Journal of the American Chemical Society, 139 (18), 6321-6328. doi: 10.1021/jacs.6b12622
2017
Journal Article
Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis
Kalantari, Mohammad, Yu, Meihua, Yang, Yannan, Strounina, Ekaterina, Gu, Zhengying, Huang, Xiaodan, Zhang, Jun, Song, Hao and Yu, Chengzhong (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10 (2), 605-617. doi: 10.1007/s12274-016-1320-6
2017
Journal Article
Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment
Kalantari, Mohammad, Yu, Meihua, Noonan, Owen, Song, Hao, Xu, Chun, Huang, Xiaodan, Xiang, Feixiang, Wang, Xiaolin and Yu, Chengzhong (2017). Rattle-type magnetic mesoporous hollow carbon as a high-performance and reusable adsorbent for water treatment. Chemosphere, 166, 109-117. doi: 10.1016/j.chemosphere.2016.09.083
2016
Journal Article
Encapsulation of selenium sulfide in double-layered hollow carbon spheres as advanced electrode material for lithium storage
Zhang, Hongwei, Zhou, Liang, Huang, Xiaodan, Song, Hao and Yu, Chengzhong (2016). Encapsulation of selenium sulfide in double-layered hollow carbon spheres as advanced electrode material for lithium storage. Nano Research, 9 (12), 3725-3734. doi: 10.1007/s12274-016-1243-2
2016
Journal Article
Hollow mesoporous carbon nanocarriers for vancomycin delivery: understanding the structure-release relationship for prolonged antibacterial performance
Nor, Yusilawati Ahmad, Zhang, Hongwei, Purwajanti, Swasmi, Song, Hao, Meka, Anand Kumar, Wang, Yue, Mitter, Neena, Mahony, Donna and Yu, Chengzhong (2016). Hollow mesoporous carbon nanocarriers for vancomycin delivery: understanding the structure-release relationship for prolonged antibacterial performance. Journal of Materials Chemistry B, 4 (43), 7014-7021. doi: 10.1039/c6tb01778a
Funding
Current funding
Supervision
Availability
- Dr Hao Song is:
- Available for supervision
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Available projects
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A nanotechnology for long-lasting oral drug delivery.
Medication adherence is required for the effectiveness of all pharmacotherapies, especially for long-term treatment of chronic illness and infectious diseases such as malaria, diabetes, and HIV. However, intensive dosage regimens with a high pill burden are associated with a low adherence rate, leading to compromised or even failure of therapies. My project aims to realize the ideal of ‘pillbox in a capsule’, i.e. taking a single tablet that will provide sustained drug release over several days, by developing a long-lasting oral drug delivery platform with prolonged gastrointestinal transit time. Inspired by bio-adhesive natural systems, where spiky surfaces enable strong adhesion, this project will engineer silica particles with a spiky morphology as well as their assembled medical devices as oral drug delivery vehicles, and their interactions at the bio-interfaces in the gastrointestinal environment will be investigated in detail. On completion, this project will produce guidelines for the rational design of novel oral drug delivery systems, and new potential clinical strategies for simplified oral medications to improve medication adherence and patient outcomes.
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Virus-mimicking nanoparticles for DNA vaccine
DNA vaccine, as the third generation vaccine technology, representing the latest biotechnological breakthrough in vaccine development. Compared to conventional recombinant vaccines usually only stimulating the antibody responses, DNA vaccine show advantages in evoking both cellular and humoral immunity to fulfill the demand in combating chronic infectious diseases. Moreover, the cost-effectiveness and fast speed of production make DNA vaccine an ideal strategy to deal with outbreaks such as SARS-COV-2 and H5N1 for the sake of both public and animal healthcare. To enable a successful DNA vaccine technology, it is critical to develop efficient gene vectors to transport and regulate the DNA molecules to be highly expressed in target cells. Mimicking the morphology of the virus, this project aims to fabricate a series of virus-like silica nanoparticles with tailored physicochemical features for plasmid DNA delivery and investigate their gene translation and vaccine performance. The completion of this project will provide fundamental understandings of the impact of designer particle nanostructure/chemistry on DNA transfection and vaccine immunogenicity.
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Nature-inspired spiky nanomaterials probed at the bio-nano interfaces
The intriguing nature systems have inspired remarkable advances in the development of functional nanomaterials for biomedical applications. Nature creations such as pollen grains and virus with spiky topological features at various length scales enable multivalent interactions at bio-interfaces, and typically exhibit intriguing surface adhesive property. This project aims to apply this nature-derived principle to engineer nanoparticles for enhanced intracellular delivery of biomolecules. Nanomaterials with functional compositions and tailored spiky nanostructures will be fabricated. Their cellular internalization process and biomolecules delivery efficiency will be evaluated. On completion of this project, a versatile and functional drug delivery platform will be established and an in-depth understanding of the spiky nanoparticle-cell interaction will be revealed.
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Antibiotic-free antibacterial nanotechnology
The overuse of antibiotics leads to ever-increasing antibiotic resistance, posing a severe threat to human health. Recent advances in nanotechnology provide new opportunities to address the challenges in bacterial infection by killing germs without using antibiotics. This project aims to develop antibiotic-free antibacterial formulations enabled by advanced nanomaterials. Functional nanomaterials with intrinsic or light-mediated bactericidal properties will be fabricated to enable efficient pathogen killing. Meanwhile, porous nanoparticles will also be engineered to serve as vehicles for the delivery of natural antibacterial compounds, formulating Pickering emulsion for stable and sparable antibacterial nano-agents. On the completion of this project, nano-formulations showing potent antibacterial property and good safety will be provided, and their antibacterial mechanisms, as well as the structure-performance relationship, will be revealed.
Supervision history
Current supervision
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Doctor Philosophy
Biomimetic Nanoparticles for Efficient Vaccine Delivery
Principal Advisor
-
Doctor Philosophy
Engineering smart nano-delivery system for mRNA therapeutics
Principal Advisor
Other advisors: Dr Ruirui Qiao
-
Doctor Philosophy
clinically-oriented synergized immunotherapy strategies for breast cancer
Principal Advisor
-
Doctor Philosophy
Engineering Spiky Nanoparticles Probed at the Nano-Bio Interfaces
Principal Advisor
Other advisors: Professor Michael Yu
-
Doctor Philosophy
Multifunctional hybrid mesoporous silica nanoparticles for stimuli-responsive delivery of antimicrobial agents
Associate Advisor
Other advisors: Professor Michael Yu
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Doctor Philosophy
Engineering encapsulation technology for enzyme immobilization
Associate Advisor
-
Doctor Philosophy
Mechanistic Study of the interaction between nulceic aicd carriers and phenotypic cells
Associate Advisor
Other advisors: Professor Michael Yu
-
Doctor Philosophy
Development of a market relevant DNA nano-vaccine platform
Associate Advisor
Other advisors: Professor Michael Yu
-
Doctor Philosophy
Synthesis and applications of non-viral gene vectors
Associate Advisor
Other advisors: Professor Michael Yu
Completed supervision
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2024
Doctor Philosophy
Engineering encapsulation technology for enzyme immobilization
Associate Advisor
-
2024
Doctor Philosophy
Synthesis and applications of non-viral gene vectors
Associate Advisor
Other advisors: Professor Michael Yu
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2023
Doctor Philosophy
Engineering core-shell-type of silica nanoparticles with controllable surface nanotopography as gene delivery vectors
Associate Advisor
Other advisors: Professor Michael Yu
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2023
Doctor Philosophy
Agriculture Nanotechnology & Materials Engineering: Agricultural Applications of Silica-Based Nanomaterials
Associate Advisor
Other advisors: Professor Michael Yu
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2022
Doctor Philosophy
Nanoparticle-Assisted Signal-Enhancement Technique for Lateral Flow Immunoassays
Associate Advisor
Other advisors: Professor Michael Yu
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2021
Doctor Philosophy
Engineered Aluminosilicate-Based Nanoparticles for Safe and Efficient Vaccine Delivery
Associate Advisor
Other advisors: Professor Linda Lua, Professor Michael Yu
Media
Enquiries
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