Overview
Background
David Cantillo studied chemistry at the University of Extremadura, Spain. In 2011, he obtained his PhD under the supervision of Prof. Jose Luis Jimenez at the same university. His PhD work focused on the experimental and theoretical study of 1,3-dipolar cycloadditions of mesoionic compounds. Then, he moved to the University of Graz as a postdoctoral researcher within the group of Prof. C. Oliver Kappe, where he gained experience in flow chemistry. In 2018, he started his independent academic career at the University of Graz as an Assistant Professor and became an Area Leader at the Research Center Pharmaceutical Engineering GmbH. David has joined the University of Queensland in 2023.
His research group focuses on synthetic organic electrochemistry. In particular, the group explores the use of electrical current to develop novel synthetic methodologies and more sustainable routes for the synthesis of medicines, as well as process scale up using continuous flow technology.
Availability
- Dr David Cantillo is:
- Available for supervision
Qualifications
- Licentiate of Chemistry, Universidad de Extremadura
- Doctoral (Research) of Organic Chemistry, Universidad de Extremadura
Research interests
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Synthetic organic electrochemistry
Development of novel synthetic methods of organic compounds, such as active pharmaceutical ingredients and agrochemicals, using electrolysis instead of chemical reagents. Scale up of electrochemical reactions using flow electrolysis cells to ensure industrial application of electrochemical methods
Research impacts
David has published over 100 papers in scientific journals that have been cited over 5000 times (H-Index=35). His research has been recognized with several awards, including the 2020 Thieme Chemistry Journals Award, the 2024 OPRD award from the ACS and the Inventor Award from UniGraz. David is member of the scientific advisory boards of Axplora and Chimica Oggi.
Works
Search Professor David Cantillo’s works on UQ eSpace
2014
Journal Article
Immobilized transition metals as catalysts for cross-couplings in continuous flow-a critical assessment of the reaction mechanism and metal leaching
Cantillo, David and Kappe, C. Oliver (2014). Immobilized transition metals as catalysts for cross-couplings in continuous flow-a critical assessment of the reaction mechanism and metal leaching. ChemCatChem, 6 (12), 3286-3305. doi: 10.1002/cctc.201402483
2014
Journal Article
Sequential nitration/hydrogenation protocol for the synthesis of triaminophloroglucinol: safe generation and use of an explosive intermediate under continuous-flow conditions
Cantillo, David, Damm, Markus, Dallinger, Doris, Bauser, Marcus, Berger, Markus and Kappe, C. Oliver (2014). Sequential nitration/hydrogenation protocol for the synthesis of triaminophloroglucinol: safe generation and use of an explosive intermediate under continuous-flow conditions. Organic Process Research and Development, 18 (11), 1360-1366. doi: 10.1021/op5001435
2014
Journal Article
A continuous-flow protocol for light-induced benzylic fluorinations
Cantillo, David, de Frutos, Oscar, Rincon, Juan A., Mateos, Carlos and Kappe, C. Oliver (2014). A continuous-flow protocol for light-induced benzylic fluorinations. The Journal of Organic Chemistry, 79 (17), 8486-8490. doi: 10.1021/jo5016757
2014
Conference Publication
α-Trifluoromethylation of ketones by metal-free visible light photoredox catalysis: Batch and continuous flow strategies
Kappe, C. Oliver and Cantillo, David (2014). α-Trifluoromethylation of ketones by metal-free visible light photoredox catalysis: Batch and continuous flow strategies. 248th National Meeting of the American-Chemical-Society (ACS), San Francisco, CA United States, 10-14 August 2014. Washington, DC United States: American Chemical Society.
2014
Journal Article
Stepwise formation of 1,3-diazolium-4-thiolates by munchnone cycloadditions: promising candidates for nonlinear optics
Cantillo, David, Avalos, Martin, Babiano, Reyes, Cintas, Pedro, Jimenez, Jose L., Light, Mark E., Palacios, Juan C. and Porro, Rocio (2014). Stepwise formation of 1,3-diazolium-4-thiolates by munchnone cycloadditions: promising candidates for nonlinear optics. The Journal of Organic Chemistry, 79 (9), 4201-4205. doi: 10.1021/jo500349g
2014
Journal Article
Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis
Cantillo, David, de Frutos, Oscar, Rincon, Juan A., Mateos, Carlos and Kappe, C. Oliver (2014). Continuous flow α-trifluoromethylation of ketones by metal-free visible light photoredox catalysis. Organic Letters, 16 (3), 896-899. doi: 10.1021/ol403650y
2014
Journal Article
Effect of configuration of 2-vinyldiazocarbonyl compounds on their reactivity: experimental and computational study
Supurgibekov, Murat B., Cantillo, David, Kappe, C. Oliver, Prakash, G. K. Surya and Nikolaev, Valerij A. (2014). Effect of configuration of 2-vinyldiazocarbonyl compounds on their reactivity: experimental and computational study. Organic and Biomolecular Chemistry, 12 (4), 682-689. doi: 10.1039/c3ob42102c
2014
Journal Article
A scalable procedure for light-induced benzylic brominations in continuous flow
Cantillo, David, de Frutos, Oscar, Rincon, Juan A., Mateos, Carlos and Kappe, C. Oliver (2014). A scalable procedure for light-induced benzylic brominations in continuous flow. The Journal of Organic Chemistry, 79 (1), 223-229. doi: 10.1021/jo402409k
2013
Journal Article
Direct preparation of nitriles from carboxylic acids in continuous flow
Cantillo, David and Kappe, C. Oliver (2013). Direct preparation of nitriles from carboxylic acids in continuous flow. The Journal of Organic Chemistry, 78 (20), 10567-10571. doi: 10.1021/jo401945r
2013
Journal Article
In situ generation of diimide from hydrazine and oxygen: continuous-flow transfer hydrogenation of olefins
Pieber, Bartholomaeus, Martinez, Sabrina Teixeira, Cantillo, David and Kappe, C. Oliver (2013). In situ generation of diimide from hydrazine and oxygen: continuous-flow transfer hydrogenation of olefins. Angewandte Chemie (International Edition), 52 (39), 10241-10244. doi: 10.1002/anie.201303528
2013
Journal Article
Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals
Cantillo, David, Moghaddam, Mojtaba Mirhosseini and Kappe, C. Oliver (2013). Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals. Journal of Organic Chemistry, 78 (9), 4530-4542. doi: 10.1021/jo400556g
2013
Conference Publication
In search for an efficient catalyst for azide-nitrile cycloadditions: The synthesis of 5-substituted-1H-tetrazoles under batch and continuous flow conditions
Kappe, C. Oliver, Cantillo, David and Gutmann, Bernhard (2013). In search for an efficient catalyst for azide-nitrile cycloadditions: The synthesis of 5-substituted-1H-tetrazoles under batch and continuous flow conditions. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans, LA United States, 7-11 April 2013. Washington, DC United States: American Chemical Society.
2013
Conference Publication
In situ generated iron oxide nanocrystals as efficient and selective catalysts for the reduction of nitroarenes in batch and continuous flow formats
Kappe, C. Oliver, Cantillo, David, Baghbanzadeh, Mostafa and Moghaddam, Mojtaba Mirhosseini (2013). In situ generated iron oxide nanocrystals as efficient and selective catalysts for the reduction of nitroarenes in batch and continuous flow formats. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans, LA United States, 7-11 April 2013. Washington, DC United States: American Chemical Society.
2013
Journal Article
On the Fischer indole synthesis of 7-ethyltryptophol-mechanistic and process intensification studies under continuous flow conditions
Gutmann, Bernhard, Gottsponer, Michael, Elsner, Petteri, Cantillo, David, Roberge, Dominique M. and Kappe, C. Oliver (2013). On the Fischer indole synthesis of 7-ethyltryptophol-mechanistic and process intensification studies under continuous flow conditions. Organic Process Research and Development, 17 (2), 294-302. doi: 10.1021/op300363s
2012
Journal Article
An experimental and computational assessment of acid-catalyzed azide-nitrile cycloadditions
Cantillo, David, Gutmann, Bernhard and Kappe, C. Oliver (2012). An experimental and computational assessment of acid-catalyzed azide-nitrile cycloadditions. The Journal of Organic Chemistry, 77 (23), 10882-10890. doi: 10.1021/jo3022742
2012
Journal Article
Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols
Damm, Markus, Nusshold, Christoph, Cantillo, David, Rechberger, Gerald N., Gruber, Karl, Sattler, Wolfgang and Kappe, C. Oliver (2012). Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols. Journal of Proteomics, 75 (18), 5533-5543. doi: 10.1016/j.jprot.2012.07.043
2012
Journal Article
On the prebiotic synthesis of D-sugars catalyzed by L-peptides: assessments from first-principles calculations
Cantillo, David, Avalos, Martin, Babiano, Reyes, Cintas, Pedro, Jimenez, Jose L. and Palacios, Juan C. (2012). On the prebiotic synthesis of D-sugars catalyzed by L-peptides: assessments from first-principles calculations. Chemistry: A European Journal, 18 (28), 8795-8799. doi: 10.1002/chem.201200466
2012
Journal Article
Direct arylation of benzene with aryl bromides using high-temperature/high-pressure process windows: expanding the scope of C-H activation chemistry
Pieber, Bartholomaus, Cantillo, David and Kappe, C. Oliver (2012). Direct arylation of benzene with aryl bromides using high-temperature/high-pressure process windows: expanding the scope of C-H activation chemistry. Chemistry: A European Journal, 18 (16), 5047-5055. doi: 10.1002/chem.201103748
2012
Journal Article
Flash flow pyrolysis: mimicking flash vacuum pyrolysis in a high-temperature/high-pressure liquid-phase microreactor environment
Cantillo, David, Sheibani, Hassan and Kappe, C. Oliver (2012). Flash flow pyrolysis: mimicking flash vacuum pyrolysis in a high-temperature/high-pressure liquid-phase microreactor environment. The Journal of Organic Chemistry, 77 (5), 2463-2473. doi: 10.1021/jo3001645
2012
Journal Article
Fast and reliable location of stationary points in a reaction path
Cantillo, David, Avalos, Martin, Babiano, Reyes, Cintas, Pedro, Jimenez, Jose L. and Palacios, Juan C. (2012). Fast and reliable location of stationary points in a reaction path. Journal of Physical Organic Chemistry, 25 (1), 77-82. doi: 10.1002/poc.1877
Supervision
Availability
- Dr David Cantillo is:
- Available for supervision
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Available projects
-
Synthetic organic electrochemisty
This project deals with the development of novel methods for the preparation of pharmaceutical intermediates using electrochemistry
Supervision history
Current supervision
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Doctor Philosophy
Mass-Transfer Control-Enabled Electrochemical Reactions
Principal Advisor
Other advisors: Professor Paul Bernhardt
Media
Enquiries
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