Overview
Background
David Cantillo studied chemistry at the University of Extremadura, Spain. In 2011, he obtained his PhD under the supervision of Prof. Jose Luis Jimenez at the same university. His PhD work focused on the experimental and theoretical study of 1,3-dipolar cycloadditions of mesoionic compounds. Then, he moved to the University of Graz as a postdoctoral researcher within the group of Prof. C. Oliver Kappe, where he gained experience in flow chemistry. In 2018, he started his independent academic career at the University of Graz as an Assistant Professor and became an Area Leader at the Research Center Pharmaceutical Engineering GmbH. David has joined the University of Queensland in 2023.
His research group focuses on synthetic organic electrochemistry. In particular, the group explores the use of electrical current to develop novel synthetic methodologies and more sustainable routes for the synthesis of medicines, as well as process scale up using continuous flow technology.
Availability
- Dr David Cantillo is:
- Available for supervision
Qualifications
- Licentiate of Chemistry, Universidad de Extremadura
- Doctoral (Research) of Organic Chemistry, Universidad de Extremadura
Research interests
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Synthetic organic electrochemistry
Development of novel synthetic methods of organic compounds, such as active pharmaceutical ingredients and agrochemicals, using electrolysis instead of chemical reagents. Scale up of electrochemical reactions using flow electrolysis cells to ensure industrial application of electrochemical methods
Research impacts
David has published over 90 papers in scientific journals that have been cited over 5000 times (H-Index=32). His research has been recognized with several awards, including the 2020 Thieme Chemistry Journals Award, the 2024 OPRD award from the ACS and the Inventor Award from UniGraz. David is member of the scientific advisory boards of Axplora and Chimica Oggi.
Works
Search Professor David Cantillo’s works on UQ eSpace
2023
Journal Article
Control of a complex multistep process for the production of mesalazine
Castillo, Ismael, Rehrl, Jakob, Sagmeister, Peter, Lebl, Rene, Kruisz, Julia, Celikovic, Selma, Sipek, Martin, Kirschneck, Dirk, Horn, Martin, Sacher, Stephan, Cantillo, David, Williams, Jason D., Khinast, Johannes G. and Kappe, Oliver (2023). Control of a complex multistep process for the production of mesalazine. Journal of Process Control, 122, 59-68. doi: 10.1016/j.jprocont.2022.12.009
2022
Journal Article
Panel discussion on... FLOW CHEMISTRY
Cantillo, David, Monedero, Martin, Dapremont, Olivier, Lusso, Carlo, McLaws, Mark, Blocher, Thomas, Wiles, Charlotte, Houldsworth, Stephen, Vizza, Alessandra, Hornung, Christian H., Kaaden, Anne, Stam, Wouter, McKay, Chris, Katz, Marianna, Borukhova, Svetlana, Kirschneck, Dirk, Ni, Xiong-Wei, Guillermin, Jean-Baptiste, Rouchet, Jean-Baptiste, Yazdanpanah, Nima, Roletto, Jacopo, Jenkins, Gareth, Poechlauer, Peter, Nuño, Manuel and Adamo, Andrea (2022). Panel discussion on... FLOW CHEMISTRY. Chimica Oggi, 40 (4), 16-41.
2022
Journal Article
Sustainable synthesis of noroxymorphone via a key electrochemical N-demethylation step
Sommer, Florian, Gerber Aeschbacher, Roman, Thurnheer, Urs, Kappe, C. Oliver and Cantillo, David (2022). Sustainable synthesis of noroxymorphone via a key electrochemical N-demethylation step. ACS Sustainable Chemistry and Engineering, 10 (27), 8988-8996. doi: 10.1021/acssuschemeng.2c02824
2022
Journal Article
Electrochemical oxidation of alcohols using nickel oxide hydroxide as heterogeneous electrocatalyst in batch and continuous flow
Jud, Wolfgang, Salazar, Chase A., Imbrogno, Joseph, Verghese, Jenson, Guinness, Steven M., Desrosiers, Jean-Nicolas, Kappe, C. Oliver and Cantillo, David (2022). Electrochemical oxidation of alcohols using nickel oxide hydroxide as heterogeneous electrocatalyst in batch and continuous flow. Organic Process Research and Development, 26 (5), 1486-1495. doi: 10.1021/acs.oprd.2c00064
2022
Journal Article
Scalable continuous flow hydrogenations using Pd/Al<sub>2</sub>O<sub>3</sub>-coated rectangular cross-section 3D-printed static mixers
Lebl, Rene, Zhu, Yutong, Ng, Derrick, Hornung, Christian H., Cantillo, David and Kappe, C. Oliver (2022). Scalable continuous flow hydrogenations using Pd/Al2O3-coated rectangular cross-section 3D-printed static mixers. Catalysis Today, 383, 55-63. doi: 10.1016/j.cattod.2020.07.046
2022
Journal Article
Synthesis of active pharmaceutical ingredients using electrochemical methods: keys to improve sustainability
Cantillo, David (2022). Synthesis of active pharmaceutical ingredients using electrochemical methods: keys to improve sustainability. Chemical Communications, 58 (5), 619-628. doi: 10.1039/d1cc06296d
2021
Other Outputs
Processes for preparing nor-opioid compounds and opioid antagonists by electrochemical N-demethylation
Glotz, Gabriel, Kappe, Christian Oliver and Cantillo, David (2021). Processes for preparing nor-opioid compounds and opioid antagonists by electrochemical N-demethylation. WO2021249708A1.
2021
Journal Article
Continuous flow synthesis of a blocked polyisocyanate: process intensification, reaction monitoring via in-line FTIR analysis, and comparative life cycle assessment
Glotz, Gabriel, Waniek, Katharina, Schöggl, Josef-Peter, Cantillo, David, Stueckler, Clemens, Arzt, Anton, Gollner, Andreas, Schipfer, Rudolf, Baumgartner, Rupert J. and Kappe, C. Oliver (2021). Continuous flow synthesis of a blocked polyisocyanate: process intensification, reaction monitoring via in-line FTIR analysis, and comparative life cycle assessment. Organic Process Research and Development, 25 (10), 2367-2379. doi: 10.1021/acs.oprd.1c00329
2021
Journal Article
A small footprint oxycodone generator based on continuous flow technology and real-time analytics
Sommer, Florian, Cantillo, David and Kappe, C. Oliver (2021). A small footprint oxycodone generator based on continuous flow technology and real-time analytics. Journal of Flow Chemistry, 11 (4), 707-715. doi: 10.1007/s41981-021-00193-y
2021
Journal Article
Electrochemical α-arylation of ketones via anodic oxidation of in situ generated silyl enol ethers
Jud, Wolfgang, Sommer, Florian, Kappe, C. Oliver and Cantillo, David (2021). Electrochemical α-arylation of ketones via anodic oxidation of in situ generated silyl enol ethers. The Journal of Organic Chemistry, 86 (22), 16026-16034. doi: 10.1021/acs.joc.1c01224
2021
Journal Article
One-pot multistep electrochemical strategy for the modular synthesis of epoxides, glycols, and aldehydes from alkenes
Jud, Wolfgang, Kappe, C. Oliver and Cantillo, David (2021). One-pot multistep electrochemical strategy for the modular synthesis of epoxides, glycols, and aldehydes from alkenes. Electrochemical Science Advances, 1 (3) e2100002, 1-9. doi: 10.1002/elsa.202100002
2021
Journal Article
Chemoselective electrochemical oxidation of secondary alcohols using a recyclable chloride-based mediator
Cantillo, David, Sommer, Florian and Kappe, C. Oliver (2021). Chemoselective electrochemical oxidation of secondary alcohols using a recyclable chloride-based mediator. Synlett, 33 (02), 166-170. doi: 10.1055/a-1511-8869
2021
Journal Article
Advanced real-time process analytics for multistep synthesis in continuous flow
Sagmeister, Peter, Lebl, Rene, Castillo, Ismael, Rehrl, Jakob, Kruisz, Julia, Sipek, Martin, Horn, Martin, Sacher, Stephan, Cantillo, David, Williams, Jason D. and Kappe, C. Oliver (2021). Advanced real-time process analytics for multistep synthesis in continuous flow. Angewandte Chemie-International Edition, 60 (15), 8139-8148. doi: 10.1002/anie.202016007
2021
Journal Article
Flow technology for telescoped generation, lithiation and electrophilic (C3) functionalization of highly strained 1-azabicyclo[1.1.0]butanes
Musci, Pantaleo, von Keutz, Timo, Belaj, Ferdinand, Degennaro, Leonardo, Cantillo, David, Kappe, C. Oliver and Luisi, Renzo (2021). Flow technology for telescoped generation, lithiation and electrophilic (C3) functionalization of highly strained 1-azabicyclo[1.1.0]butanes. Angewandte Chemie-International Edition, 60 (12), 6395-6399. doi: 10.1002/anie.202014881
2021
Journal Article
Electrochemically enabled one‐pot multistep synthesis of C19 androgen steroids
Sommer, Florian, Kappe, C. Oliver and Cantillo, David (2021). Electrochemically enabled one‐pot multistep synthesis of C19 androgen steroids. Chemistry: A European Journal, 27 (19), 6044-6049. doi: 10.1002/chem.202100446
2021
Journal Article
Sustainable electrochemical decarboxylative acetoxylation of aminoacids in batch and continuous flow
Köckinger, Manuel, Hanselmann, Paul, Roberge, Dominique M., Geotti-Bianchini, Piero, Kappe, C. Oliver and Cantillo, David (2021). Sustainable electrochemical decarboxylative acetoxylation of aminoacids in batch and continuous flow. Green Chemistry, 23 (6), 2382-2390. doi: 10.1039/d1gc00201e
2020
Journal Article
A continuous flow bromodimethylsulfonium bromide generator: application to the synthesis of 2-arylaziridines from styrenes
Prieschl, Michael, Cantillo, David and Kappe, C. Oliver (2020). A continuous flow bromodimethylsulfonium bromide generator: application to the synthesis of 2-arylaziridines from styrenes. Journal of Flow Chemistry, 11 (2), 117-125. doi: 10.1007/s41981-020-00125-2
2020
Journal Article
Continuous on demand generation of acrolein from glycerol using a reactive distillation strategy
Strauss, Franz J., Pöchlauer, Peter, Schuster, Christian, Kohls, Paul, Steinhofer, Stefan, Zinganell, Christopher, Gutmann, Bernhard, Cantillo, David and Kappe, C. Oliver (2020). Continuous on demand generation of acrolein from glycerol using a reactive distillation strategy. Chimica Oggi/Chemistry Today, 38 (6), 24-27.
2020
Journal Article
Development and assembly of a flow cell for single‐pass continuous electroorganic synthesis using laser‐cut components
Jud, Wolfgang, Kappe, C. Oliver and Cantillo, David (2020). Development and assembly of a flow cell for single‐pass continuous electroorganic synthesis using laser‐cut components. Chemistry–Methods, 1 (1), 36-41. doi: 10.1002/cmtd.202000042
2020
Journal Article
Organomagnesium based flash chemistry: continuous flow generation and utilization of halomethylmagnesium intermediates
von Keutz, Timo, Cantillo, David and Kappe, C. Oliver (2020). Organomagnesium based flash chemistry: continuous flow generation and utilization of halomethylmagnesium intermediates. Organic Letters, 22 (19), 7537-7541. doi: 10.1021/acs.orglett.0c02725
Supervision
Availability
- Dr David Cantillo is:
- Available for supervision
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Available projects
-
Synthetic organic electrochemisty
This project deals with the development of novel methods for the preparation of pharmaceutical intermediates using electrochemistry
Media
Enquiries
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