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Dr John-Paul Tung
Dr

John-Paul Tung

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Overview

Background

John-Paul Tung is a Senior Research Fellow at Australian Red Cross Lifeblood (Lifeblood). He leads a program of research focused on the changes that occur in blood in between collection and transfusion, as well as how these changes might impact transfused patients. Particular focuses are on transfusion-related acute lung inujry (TRALI), transfusion-associated circulatory overload (TACO), and extracellular vesicles. He leads a research team of five Senior Research Assistants and three Research Assistants. He also supervises several PhD and Masters students. He holds an Honorary Senior Research Fellow position with the Faculty of Medicine at UQ. He also holds an adjunct Associate Professor position with the University of the Sunshine Coast and an adjunct Senior Lecturer position with QUT. He is also a former Secretary and Council Member of the International Society of Blood Transfusion's Young Professionals Council.

John-Paul completed a Bachelor of Science at UQ in 1999, after which he worked as a Scientist in nucleic acid testing in Brisbane, Melbourne and London. After returning to Brisbane, he commenced work as a Research Scientist with Lifeblood (formerly the Blood Service) in 2007. John-Paul then commenced a PhD with UQ and Prince Charles Hospital's Critical Care Research Group in 2008. His PhD, conferred in 2012, invovled the development of the first large animal model of TRALI using sheep, and resulted in several awards including best paper prizes from the International Society of Blood Transfusion and the Prince Charles Hospital as well as other awards from the Australian and New Zealand Society of Blood Transfusion and the British Blood Transfusion Society.

Availability

Dr John-Paul Tung is:
Available for supervision

Research impacts

As well as internal Lifeblood research project funding, John-Paul has been an investigator on over 20 competitive external grants worth over $7.5 million, including from the NHMRC, the ARC, and the Emergency Medicine Foundation. John-Paul has published over 40 papers including in American Journal of Respiratory and Critical Care Medicine (JIF 30.5), Intensive Care Medicine (JIF 17.4), Critical Care (JIF 9.1), and Blood Reviews (JIF 8.3). He has presented at international and national conferences, inculding invited presenations at the International Society of Blood Transfusion Congress, the Royal College of Pathologists Association Pathology Update, and the Brazilian Congress of Hematology, Hemotherapy, and Cellular Therapy. He has supervised over 20 research students including three PhD completions, two Masters completions, and eight Honours completions. He has several on-going academic and clincal collaborations including with the the Royal Brisbane and Women's Hospital, the Prince Charles Hospital, the Australian Defence Force, and the Baker Institute.

Works

Search Professor John-Paul Tung’s works on UQ eSpace

72 works between 2008 and 2025

21 - 40 of 72 works

2021

Journal Article

A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death

See Hoe, Louise E., Wildi, Karin, Obonyo, Nchafatso G., Bartnikowski, Nicole, McDonald, Charles, Sato, Kei, Heinsar, Silver, Engkilde-Pedersen, Sanne, Diab, Sara, Passmore, Margaret R., Wells, Matthew A., Boon, Ai-Ching, Esguerra, Arlanna, Platts, David G., James, Lynnette, Bouquet, Mahe, Hyslop, Kieran, Shuker, Tristan, Ainola, Carmen, Colombo, Sebastiano M., Wilson, Emily S., Millar, Jonathan E., Malfertheiner, Maximillian V., Reid, Janice D., O’Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Sato, Noriko, He, Ting ... Fraser, John F. (2021). A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death. Intensive Care Medicine Experimental, 9 (1) 60, 1-24. doi: 10.1186/s40635-021-00425-4

A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death

2021

Journal Article

An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management

Dyer, Wayne B., Tung, John-Paul, Li Bassi, Gianluigi, Wildi, Karin, Jung, Jae-Seung, Colombo, Sebastiano Maria, Rozencwajg, Sacha, Simonova, Gabriela, Chiaretti, Sara, Temple, Fergal T., Ainola, Carmen, Shuker, Tristan, Palmieri, Chiara, Shander, Aryeh, Suen, Jacky Y., Irving, David O. and Fraser, John F. (2021). An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management. Shock, 56 (6), 1080-1091. doi: 10.1097/SHK.0000000000001805

An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management

2021

Conference Publication

Anti-HNA-3a Alloantibodies Can Cause Differential Endothelial Damage through a Direct Neutrophil Activation Pathway

Radenkovic, Filip, Chiaretti, Sara, Burton, Mark, Hassell, Penny, Bui, Xuan, Flower, Robert and Tung, John-Paul (2021). Anti-HNA-3a Alloantibodies Can Cause Differential Endothelial Damage through a Direct Neutrophil Activation Pathway. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-152047

Anti-HNA-3a Alloantibodies Can Cause Differential Endothelial Damage through a Direct Neutrophil Activation Pathway

2021

Conference Publication

Quantification and Characterisation of Nano-Sized Particles in Cryoprecipitate Units

Hwang, Ji Hui, Tung, John-Paul, Flower, Robert L. and Pecheniuk, Natalie M. (2021). Quantification and Characterisation of Nano-Sized Particles in Cryoprecipitate Units. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-147793

Quantification and Characterisation of Nano-Sized Particles in Cryoprecipitate Units

2021

Conference Publication

The Impact of Revised Definitions for TACO and TRALI on Hemovigilance Reporting

Yuan, Yin, Dennington, Peta, Daly, James J., Tung, John-Paul and Baidya, Shoma (2021). The Impact of Revised Definitions for TACO and TRALI on Hemovigilance Reporting. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-145294

The Impact of Revised Definitions for TACO and TRALI on Hemovigilance Reporting

2020

Journal Article

Ovine red cell concentrates for transfusion research – is the storage lesion comparable to human red cell concentrates?

Simonova, Gabriela, Wellburn, Rebecca, Fung, Yoke Lin, Fraser, John F. and Tung, John‐Paul (2020). Ovine red cell concentrates for transfusion research – is the storage lesion comparable to human red cell concentrates?. Vox Sanguinis, 116 (5) vox.13020, 524-532. doi: 10.1111/vox.13020

Ovine red cell concentrates for transfusion research – is the storage lesion comparable to human red cell concentrates?

2020

Journal Article

Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma

Bouquet, Mahé, Passmore, Margaret R., See Hoe, Louise E., Tung, John-Paul, Simonova, Gabriela, Boon, Ai-Ching and Fraser, John F. (2020). Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma. Journal of Immunological Methods, 486 112835, 112835. doi: 10.1016/j.jim.2020.112835

Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma

2020

Conference Publication

Coronary artery bypass grafting surgery differentially modulates the leucocyte gene expression profile

Perros, Alexis J., Chong, Fenny, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Rooks, Kelly, Faddy, Helen M., Hewlett, Elise, Naidoo, Rishendran, Tung, John-Paul, Fraser, John F., Tesar, Peter, Ziegenfuss, Marc, Smith, Susan, O’Brien, Donalee, Flower, Robert L. and Dean, Melinda M. (2020). Coronary artery bypass grafting surgery differentially modulates the leucocyte gene expression profile. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.69.18

Coronary artery bypass grafting surgery differentially modulates the leucocyte gene expression profile

2020

Conference Publication

Autologous intraoperative cell salvage ameliorates suppression of transfusion-related monocyte and dendritic cell inflammatory responses

Dean, Melinda M., Obeysekera, Maheshi P., Tran, Thu V., Sturgess, David, Wyssusek, Kerstin, Van Zundert, Andrea, Gordon, Louisa G., Da Silva, D., Punnasseril, J., Tung, John-Paul, Flower, Robert L. and Roets, Michelle (2020). Autologous intraoperative cell salvage ameliorates suppression of transfusion-related monocyte and dendritic cell inflammatory responses. Immunology 2020™ Meeting, Honolulu, HI United States, 8 - 12 May 2020. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.204.supp.220.31

Autologous intraoperative cell salvage ameliorates suppression of transfusion-related monocyte and dendritic cell inflammatory responses

2020

Journal Article

Coronary artery bypass grafting is associated with immunoparalysis of monocytes and dendritic cells

Perros, Alexis J., Esguerra‐Lallen, Arlanna, Rooks, Kelly, Chong, Fenny, Engkilde‐Pedersen, Sanne, Faddy, Helen M., Hewlett, Elise, Naidoo, Rishendran, Tung, John‐Paul, Fraser, John F., Tesar, Peter, Ziegenfuss, Marc, Smith, Susan, O’Brien, Donalee, Flower, Robert L. and Dean, Melinda M. (2020). Coronary artery bypass grafting is associated with immunoparalysis of monocytes and dendritic cells. Journal of Cellular and Molecular Medicine, 24 (8) jcmm.15154, 4791-4803. doi: 10.1111/jcmm.15154

Coronary artery bypass grafting is associated with immunoparalysis of monocytes and dendritic cells

2020

Journal Article

Intraoperative cell salvage as an alternative to allogeneic (donated) blood transfusion: a prospective observational evaluation of the immune response profile

Roets, Michelle, Sturgess, David John, Obeysekera, Maheshi Prabodani, Tran, Thu Vinh, Wyssusek, Kerstin Hildegard, Punnasseril, Jaisil Eldo Jos, da Silva, Diana, van Zundert, Andre, Perros, Alexis Jacqueline, Tung, John Paul, Flower, Robert Lewis Powell and Dean, Melinda Margaret (2020). Intraoperative cell salvage as an alternative to allogeneic (donated) blood transfusion: a prospective observational evaluation of the immune response profile. Cell Transplantation, 29, 096368972096626. doi: 10.1177/0963689720966265

Intraoperative cell salvage as an alternative to allogeneic (donated) blood transfusion: a prospective observational evaluation of the immune response profile

2019

Journal Article

Fresh frozen plasma and platelet concentrate storage duration not associated with in hospital mortality risk

Ng, Monica Suet Ying, Hay, Karen, Choy, Joleen, Middelburg, Rutger A., Tung, John-Paul and Fraser, John Francis (2019). Fresh frozen plasma and platelet concentrate storage duration not associated with in hospital mortality risk. Vox Sanguinis, 114 (8) vox.12838, 835-841. doi: 10.1111/vox.12838

Fresh frozen plasma and platelet concentrate storage duration not associated with in hospital mortality risk

2019

Conference Publication

Coronary artery bypass grafting surgery is associated with immunoparalysis of monocytes and dendritic cells

Perros, Alexis J., Esguerra-Lallen, Arlanna, Rooks, Kelly, Chong, Fenny N., Engkilde-Pedersen, Sanne, Faddy, Helen M., Hewlett, Elise, Naidoo, Rishendran, Tung, John-Paul, Fraser, John F., Tesar, Peter, Ziegenfuss, Marc, Smith, Susan, O'Brien, Donalee, Flower, Robert L. and Dean, Melinda M. (2019). Coronary artery bypass grafting surgery is associated with immunoparalysis of monocytes and dendritic cells. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.182.69

Coronary artery bypass grafting surgery is associated with immunoparalysis of monocytes and dendritic cells

2019

Journal Article

Non-antibody mediated transfusion-related acute lung injury an enigma

Fung, Yoke Lin and Tung, John-Paul (2019). Non-antibody mediated transfusion-related acute lung injury an enigma. Annals of Blood, 4 (April) 7, 7. doi: 10.21037/aob.2019.03.02

Non-antibody mediated transfusion-related acute lung injury an enigma

2019

Journal Article

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

Passmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

2019

Journal Article

Endothelialized flow models for blood transfusion research

Ng, Monica S. Y., Suen, Jacky Y., Tung, John-Paul and Fraser, John F. (2019). Endothelialized flow models for blood transfusion research. Haematologica, 104 (3), 428-434. doi: 10.3324/haematol.2018.205203

Endothelialized flow models for blood transfusion research

2019

Journal Article

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

2018

Journal Article

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

2018

Journal Article

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

2018

Journal Article

How different animal models help us understand TRALI

Fung, Y. L. and Tung, J. P. (2018). How different animal models help us understand TRALI. ISBT Science Series, 13 (3), 197-205. doi: 10.1111/voxs.12423

How different animal models help us understand TRALI

Supervision

Availability

Dr John-Paul Tung is:
Available for supervision

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Media

Enquiries

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