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Dr John-Paul Tung
Dr

John-Paul Tung

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Overview

Background

John-Paul Tung is a Senior Research Fellow at Australian Red Cross Lifeblood (Lifeblood). He leads a program of research focused on the changes that occur in blood in between collection and transfusion, as well as how these changes might impact transfused patients. Particular focuses are on transfusion-related acute lung inujry (TRALI), transfusion-associated circulatory overload (TACO), and extracellular vesicles. He leads a research team of five Senior Research Assistants and three Research Assistants. He also supervises several PhD and Masters students. He holds an Honorary Senior Research Fellow position with the Faculty of Medicine at UQ. He also holds an adjunct Associate Professor position with the University of the Sunshine Coast and an adjunct Senior Lecturer position with QUT. He is also a former Secretary and Council Member of the International Society of Blood Transfusion's Young Professionals Council.

John-Paul completed a Bachelor of Science at UQ in 1999, after which he worked as a Scientist in nucleic acid testing in Brisbane, Melbourne and London. After returning to Brisbane, he commenced work as a Research Scientist with Lifeblood (formerly the Blood Service) in 2007. John-Paul then commenced a PhD with UQ and Prince Charles Hospital's Critical Care Research Group in 2008. His PhD, conferred in 2012, invovled the development of the first large animal model of TRALI using sheep, and resulted in several awards including best paper prizes from the International Society of Blood Transfusion and the Prince Charles Hospital as well as other awards from the Australian and New Zealand Society of Blood Transfusion and the British Blood Transfusion Society.

Availability

Dr John-Paul Tung is:
Available for supervision

Research impacts

As well as internal Lifeblood research project funding, John-Paul has been an investigator on over 20 competitive external grants worth over $7.5 million, including from the NHMRC, the ARC, and the Emergency Medicine Foundation. John-Paul has published over 40 papers including in American Journal of Respiratory and Critical Care Medicine (JIF 30.5), Intensive Care Medicine (JIF 17.4), Critical Care (JIF 9.1), and Blood Reviews (JIF 8.3). He has presented at international and national conferences, inculding invited presenations at the International Society of Blood Transfusion Congress, the Royal College of Pathologists Association Pathology Update, and the Brazilian Congress of Hematology, Hemotherapy, and Cellular Therapy. He has supervised over 20 research students including three PhD completions, two Masters completions, and eight Honours completions. He has several on-going academic and clincal collaborations including with the the Royal Brisbane and Women's Hospital, the Prince Charles Hospital, the Australian Defence Force, and the Baker Institute.

Works

Search Professor John-Paul Tung’s works on UQ eSpace

67 works between 2008 and 2024

41 - 60 of 67 works

2017

Conference Publication

Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI)

Tung, John-Paul, Simonova, Gabriela, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Sultana, Annette, Hewlett, Elise, Obonyo, Nchafatso, Millar, Jonathan, Flower, Robert and Fraser, John (2017). Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI). Pathology Update 2017, Sydney, NSW Australia, 24-26 February 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2016.12.309

Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI)

2017

Conference Publication

Modulation of immune responses in patients following cardiac surgery

Perros, Alexis J., Esguerra-Lallen, Arlanna, Rooks, Kelly, Chong, Fenny, Flower, Robert L., Pedersen, Sanne Engkilde, Naidoo, Rishendran, Tung, John-Paul, Fraser, John, Tesar, Peter, Ziegenfuss, Marc, Smith, Susan, O’Brien, Donalee and Dean, Melinda M. (2017). Modulation of immune responses in patients following cardiac surgery. Pathology Update 2017, Sydney, NSW Australia, 24-26 February 2017. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2016.12.317

Modulation of immune responses in patients following cardiac surgery

2017

Journal Article

Procoagulant role of microparticles in routine storage of packed red blood cells: potential risk for prothrombotic post-transfusion complications

Aung, Htet Htet, Tung, John-Paul, Dean, Melinda M., Flower, Robert L. and Pecheniuk, Natalie M. (2017). Procoagulant role of microparticles in routine storage of packed red blood cells: potential risk for prothrombotic post-transfusion complications. Pathology, 49 (1), 62-69. doi: 10.1016/j.pathol.2016.10.001

Procoagulant role of microparticles in routine storage of packed red blood cells: potential risk for prothrombotic post-transfusion complications

2016

Journal Article

Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support

Passmore, Margaret R., Fung, Yoke L., Simonova, Gabriela, Foley, Samuel R., Dunster, Kimble R., Diab, Sara D., Tung, John-Paul, Minchinton, Robyn M., McDonald, Charles I., Anstey, Chris M., Shekar, Kiran and Fraser, John F. (2016). Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support. AJP - Lung Cellular and Molecular Physiology, 311 (6), L1202-L1212. doi: 10.1152/ajplung.00296.2016

Inflammation and lung injury in an ovine model of extracorporeal membrane oxygenation support

2016

Conference Publication

A Histologic Approach to Qualify Lung Tissue Damage in a Sheep Model of Transfusion-Related Lung Injury: Role of Red Blood Cell Storage Duration and Heat Treatment

Roche, Elise, Passmore, Margaret, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Bierman, Wesley, Fraser, John and Tung, John-Paul (2016). A Histologic Approach to Qualify Lung Tissue Damage in a Sheep Model of Transfusion-Related Lung Injury: Role of Red Blood Cell Storage Duration and Heat Treatment. 2016 American Society of Clincial Pathology (ASCP) Annual Meeting, Las Vegas, NV United States, 14 -16 September 2016. Cary, NC United States: Oxford University Press.

A Histologic Approach to Qualify Lung Tissue Damage in a Sheep Model of Transfusion-Related Lung Injury: Role of Red Blood Cell Storage Duration and Heat Treatment

2016

Conference Publication

The potential of inflammatory responses to contribute to the development of transfusion-related acute lung injury (TRALI)

Sultana, A., Meka, D., Dean, M. M., Simonova, G., Christensen, A-M, Flower, R. L. and Tung, J-P (2016). The potential of inflammatory responses to contribute to the development of transfusion-related acute lung injury (TRALI). International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL.

The potential of inflammatory responses to contribute to the development of transfusion-related acute lung injury (TRALI)

2015

Journal Article

Effects of packed red blood cell storage duration on post-transfusion clinical outcomes: a meta-analysis and systematic review

Ng, Monica Suet Ying, Ng, Angela Suet Yeung, Chan, Jessica, Tung, John-Paul and Fraser, John Francis (2015). Effects of packed red blood cell storage duration on post-transfusion clinical outcomes: a meta-analysis and systematic review. Intensive Care Medicine, 41 (12), 2087-2097. doi: 10.1007/s00134-015-4078-5

Effects of packed red blood cell storage duration on post-transfusion clinical outcomes: a meta-analysis and systematic review

2015

Journal Article

Hepatitis C virus genotype 4 in England: diversity and demographic associations

Ngui, Siew-Lin, Brant, Lisa, Markov, Peter V., Tung, John-Paul, Pybus, Oliver G., Teo, Chong-Gee and Ramsay, Mary E. (2015). Hepatitis C virus genotype 4 in England: diversity and demographic associations. Journal of Medical Virology, 87 (3), 417-423. doi: 10.1002/jmv.24069

Hepatitis C virus genotype 4 in England: diversity and demographic associations

2014

Journal Article

Letter: the need for a definitive clinical trial of cryopreserved red blood cells

Milford, Elissa M., Tung, John Paul and Reade, Michael C. (2014). Letter: the need for a definitive clinical trial of cryopreserved red blood cells. Journal of Trauma and Acute Care Surgery, 77 (6), 1004-1004. doi: 10.1097/TA.0000000000000463

Letter: the need for a definitive clinical trial of cryopreserved red blood cells

2014

Conference Publication

Potential Role of Bioactive Lipids in the Development of Non-Antibody Mediated Transfusion-Related Acute Lung Injury (TRALI)

Tung, John-Paul, Meka, Denisa, Sultana, Annette J., Simonova, Gabriela, Christensen, Anne-Marie, Flower, Robert L. and Dean, Melinda M. (2014). Potential Role of Bioactive Lipids in the Development of Non-Antibody Mediated Transfusion-Related Acute Lung Injury (TRALI). WASHINGTON: AMER SOC HEMATOLOGY.

Potential Role of Bioactive Lipids in the Development of Non-Antibody Mediated Transfusion-Related Acute Lung Injury (TRALI)

2014

Journal Article

Neutrophil antibodies are clinically important

Fung, Y. L., Tung, J. P. and Minchinton, R. M. (2014). Neutrophil antibodies are clinically important. ISBT Science Series, 9 (1), 253-257. doi: 10.1111/voxs.12062

Neutrophil antibodies are clinically important

2014

Journal Article

An age-of-blood transfusion trial in the trauma setting is crucial and animal models may help inform trial design

Milford, Elissa M., Reade, Michael C., Colone, Lieutenant, Shekar, Kiran, Tung, John-Paul and Fraser, John F. (2014). An age-of-blood transfusion trial in the trauma setting is crucial and animal models may help inform trial design. Critical Care and Resuscitation, 16 (2), 149-150.

An age-of-blood transfusion trial in the trauma setting is crucial and animal models may help inform trial design

2014

Journal Article

Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care

Chemonges, Saul, Shekar, Kiran, Tung, John-Paul, Dunster, Kimble R., Diab, Sara, Platts, David, Watts, Ryan P., Gregory, Shaun D., Foley, Samuel, Simonova, Gabriela, McDonald, Charles, Hayes, Rylan, Bellpart, Judith, Timms, Daniel, Chew, Michelle, Fung, Yoke L., Toon, Michael, Maybauer, Marc O. and Fraser, John F. (2014). Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care. BioMed Research International, 2014 (468309) 468309, 1-17. doi: 10.1155/2014/468309

Optimal management of the critically ill: anaesthesia, monitoring, data capture, and point-of-care technological practices in ovine models of critical care

2014

Journal Article

Proteogenomics of selective susceptibility to endotoxin using circulating acute phase biomarkers and bioassay development in sheep: a review

Chemonges, Saul, Tung, John-Paul and Fraser, John F. (2014). Proteogenomics of selective susceptibility to endotoxin using circulating acute phase biomarkers and bioassay development in sheep: a review. Proteome Science, 12 12, 1-12. doi: 10.1186/1477-5956-12-12

Proteogenomics of selective susceptibility to endotoxin using circulating acute phase biomarkers and bioassay development in sheep: a review

2014

Journal Article

A comprehensive ovine model of blood transfusion

Simonova, G., Tung, J. P., Fraser, J. F., Do, H. L., Staib, A., Chew, M. S., Dunster, K. R., Glenister, K. M., Jackson, D. E. and Fung, Y. L. (2014). A comprehensive ovine model of blood transfusion. Vox Sanguinis, 106 (2), 153-160. doi: 10.1111/vox.12076

A comprehensive ovine model of blood transfusion

2013

Journal Article

Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage

Fung, Y. L., Tung, J. P., Foley, S. R., Simonova, G., Thom, O., Staib, A., Collier, J., Dunster, K. R., Solano, C., Shekar, K., Chew, M. S. and Fraser, J. F. (2013). Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage. Vox Sanguinis, 105 (2), 150-158. doi: 10.1111/vox.12032

Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage

2013

Conference Publication

The Ovine Packed Red Blood Cell Storage Lesion: Characterisation and Comparison to That of Human Packed Red Blood Cells

Simonova, G., Fung, Y. L., Glenister, K. M., Fraser, J. F. and Tung, J-P (2013). The Ovine Packed Red Blood Cell Storage Lesion: Characterisation and Comparison to That of Human Packed Red Blood Cells. HOBOKEN: WILEY-BLACKWELL.

The Ovine Packed Red Blood Cell Storage Lesion: Characterisation and Comparison to That of Human Packed Red Blood Cells

2012

Other Outputs

Development of an ovine model of transfusion-related acute lung injury (TRALI)

Tung, John-Paul (2012). Development of an ovine model of transfusion-related acute lung injury (TRALI). PhD Thesis, School of Medicine, The University of Queensland.

Development of an ovine model of transfusion-related acute lung injury (TRALI)

2012

Journal Article

Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI)

Tung, John-Paul, Fraser, John F., Nataatmadja, Maria, Colebourne, Kathryn I., Barnett, Adrian G., Glenister, Kristen M., Zhou, Anna Y., Wood, Peter, Silliman, Christopher C. and Fung, Yoke L. (2012). Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI). Critical Care, 16 (1) R19, R19.1-R19.14. doi: 10.1186/cc11178

Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI)

2011

Journal Article

A novel in vivo ovine model of transfusion-related acute lung injury (TRALI)

Tung, J. P., Fung, Y. L., Nataatmadja, M., Colebourne, K. I., Esmaeel, H. M., Wilson, K., Barnett, A. G., Wood, P., Silliman, C. C. and Fraser, J. F. (2011). A novel in vivo ovine model of transfusion-related acute lung injury (TRALI). Vox Sanguinis, 100 (2), 219-230. doi: 10.1111/j.1423-0410.2010.01381.x

A novel in vivo ovine model of transfusion-related acute lung injury (TRALI)

Funding

Past funding

  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Dr John-Paul Tung is:
Available for supervision

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Media

Enquiries

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