Overview
Background
John-Paul Tung is a Senior Research Fellow at Australian Red Cross Lifeblood (Lifeblood). He leads a program of research focused on the changes that occur in blood in between collection and transfusion, as well as how these changes might impact transfused patients. Particular focuses are on transfusion-related acute lung inujry (TRALI), transfusion-associated circulatory overload (TACO), and extracellular vesicles. He leads a research team of five Senior Research Assistants and three Research Assistants. He also supervises several PhD and Masters students. He holds an Honorary Senior Research Fellow position with the Faculty of Medicine at UQ. He also holds an adjunct Associate Professor position with the University of the Sunshine Coast and an adjunct Senior Lecturer position with QUT. He is also a former Secretary and Council Member of the International Society of Blood Transfusion's Young Professionals Council.
John-Paul completed a Bachelor of Science at UQ in 1999, after which he worked as a Scientist in nucleic acid testing in Brisbane, Melbourne and London. After returning to Brisbane, he commenced work as a Research Scientist with Lifeblood (formerly the Blood Service) in 2007. John-Paul then commenced a PhD with UQ and Prince Charles Hospital's Critical Care Research Group in 2008. His PhD, conferred in 2012, invovled the development of the first large animal model of TRALI using sheep, and resulted in several awards including best paper prizes from the International Society of Blood Transfusion and the Prince Charles Hospital as well as other awards from the Australian and New Zealand Society of Blood Transfusion and the British Blood Transfusion Society.
Availability
- Dr John-Paul Tung is:
- Available for supervision
Research impacts
As well as internal Lifeblood research project funding, John-Paul has been an investigator on over 20 competitive external grants worth over $7.5 million, including from the NHMRC, the ARC, and the Emergency Medicine Foundation. John-Paul has published over 40 papers including in American Journal of Respiratory and Critical Care Medicine (JIF 30.5), Intensive Care Medicine (JIF 17.4), Critical Care (JIF 9.1), and Blood Reviews (JIF 8.3). He has presented at international and national conferences, inculding invited presenations at the International Society of Blood Transfusion Congress, the Royal College of Pathologists Association Pathology Update, and the Brazilian Congress of Hematology, Hemotherapy, and Cellular Therapy. He has supervised over 20 research students including three PhD completions, two Masters completions, and eight Honours completions. He has several on-going academic and clincal collaborations including with the the Royal Brisbane and Women's Hospital, the Prince Charles Hospital, the Australian Defence Force, and the Baker Institute.
Works
Search Professor John-Paul Tung’s works on UQ eSpace
2013
Journal Article
Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage
Fung, Y. L., Tung, J. P., Foley, S. R., Simonova, G., Thom, O., Staib, A., Collier, J., Dunster, K. R., Solano, C., Shekar, K., Chew, M. S. and Fraser, J. F. (2013). Stored blood transfusion induces transient pulmonary arterial hypertension without impairing coagulation in an ovine model of nontraumatic haemorrhage. Vox Sanguinis, 105 (2), 150-158. doi: 10.1111/vox.12032
2013
Conference Publication
The Ovine Packed Red Blood Cell Storage Lesion: Characterisation and Comparison to That of Human Packed Red Blood Cells
Simonova, G., Fung, Y. L., Glenister, K. M., Fraser, J. F. and Tung, J-P (2013). The Ovine Packed Red Blood Cell Storage Lesion: Characterisation and Comparison to That of Human Packed Red Blood Cells. HOBOKEN: WILEY-BLACKWELL.
2012
Other Outputs
Development of an ovine model of transfusion-related acute lung injury (TRALI)
Tung, John-Paul (2012). Development of an ovine model of transfusion-related acute lung injury (TRALI). PhD Thesis, School of Medicine, The University of Queensland.
2012
Journal Article
Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI)
Tung, John-Paul, Fraser, John F., Nataatmadja, Maria, Colebourne, Kathryn I., Barnett, Adrian G., Glenister, Kristen M., Zhou, Anna Y., Wood, Peter, Silliman, Christopher C. and Fung, Yoke L. (2012). Age of blood and recipient factors determine the severity of transfusion-related acute lung injury (TRALI). Critical Care, 16 (1) R19, R19.1-R19.14. doi: 10.1186/cc11178
2011
Journal Article
A novel in vivo ovine model of transfusion-related acute lung injury (TRALI)
Tung, J. P., Fung, Y. L., Nataatmadja, M., Colebourne, K. I., Esmaeel, H. M., Wilson, K., Barnett, A. G., Wood, P., Silliman, C. C. and Fraser, J. F. (2011). A novel in vivo ovine model of transfusion-related acute lung injury (TRALI). Vox Sanguinis, 100 (2), 219-230. doi: 10.1111/j.1423-0410.2010.01381.x
2011
Conference Publication
Evidence behind the pathophysiology of TRALI
Fung, Y. L., Tung, J. P., Minchinton, R. M. and Fraser, J. F. (2011). Evidence behind the pathophysiology of TRALI. unknown, unknown, unknown. MALDEN: WILEY-BLACKWELL.
2011
Conference Publication
A validated ovine model for blood collection, processing, compatibility testing and transfusion
Fung, Y. L., Do, H. L., Tung, J. P., Collier, J. and Fraser, J. F. (2011). A validated ovine model for blood collection, processing, compatibility testing and transfusion. unknown, unknown, unknown. Oxford, United Kingdom: Wiley-Blackwell Publishing.
2010
Conference Publication
A novel in-vivo ovine model of transfusion-related acute lung injury (TRALI)
Tung, J. P., Fraser, J. F., Nataatmadja, M., Colebourne, K. I., Esmaeel, H. M., Wilson, K., Barnett, A. G., Silliman, C. C., Wood, P. and Fung, Yoke Lin (2010). A novel in-vivo ovine model of transfusion-related acute lung injury (TRALI). XIth European Symposium on Platelet and Granulocyte Immunobiology, Beaune, France, 21-24 October 2010. Oxford, United Kingdom: Wiley-Blackwell Publishing.
2010
Conference Publication
Dissimilar respiratory and hemodynamic responses in TRALI induced by stored red cells and whole blood platelets
Tung, John-Paul, Fraser, John F., Nataatmadja, Maria, Barnett, Adrian G., Colebourne, Kathryn I., Glenister, Kristen M., Zhou, Anna Y., Wood, Peter, Silliman, Christopher C. and Fung, Yoke Lin (2010). Dissimilar respiratory and hemodynamic responses in TRALI induced by stored red cells and whole blood platelets. 52nd Annual Meeting of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 4-7 Dec 2010. Orlando, FL, United States: American Society of Hematology.
2009
Journal Article
Respiratory burst function of ovine neutrophils
Tung, John-Paul, Fraser, John F., Wood, Peter and Fung, Yoke L. (2009). Respiratory burst function of ovine neutrophils. BMC Immunology, 10 (1) 25, 25.1-25.11. doi: 10.1186/1471-2172-10-25
2009
Journal Article
Donor mannose-binding lectin deficiency increases the likelihood of clinically significant infection after liver transplantation
Worthley, Daniel L., Johnson, Douglas F., Eisen, Damon P., Dean, Melinda M., Heatley, Susan L., Tung, John-Paul, Scott, Justin, Padbury, Robert T. A., Harley, Hugh A., Bardy, Peter G., Angus, Peter W. and Mullighan, Charles G. (2009). Donor mannose-binding lectin deficiency increases the likelihood of clinically significant infection after liver transplantation. Clinical Infectious Diseases, 48 (4), 410-417. doi: 10.1086/596313
2008
Conference Publication
Donor-derived mannose-binding lectin deficiency increases the risk of infection after liver transplantation
Worthley, D. L., Johnson, D. F., Eisen, D. P., Dean, M. M., Heatley, S., Tung, J-P, Scott, J., Padbury, R., Harley, H., Mullighan, C. G., Angus, P. W. and Bardy, P. G. (2008). Donor-derived mannose-binding lectin deficiency increases the risk of infection after liver transplantation. WILEY-BLACKWELL PUBLISHING, INC.
Supervision
Availability
- Dr John-Paul Tung is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Completed supervision
-
2020
Doctor Philosophy
Characterisation of immune responses to standard stored and cryopreserved blood components in sheep in vitro models of transfusion
Principal Advisor
Other advisors: Professor Michael Reade
-
2023
Doctor Philosophy
The role of the endothelial glycocalyx in severe trauma
Associate Advisor
Other advisors: Professor Michael Reade
-
2019
Doctor Philosophy
A Translational Approach to Potential Toxicity of Stored Blood Components
Associate Advisor
Other advisors: Dr Jacky Suen, Professor John Fraser
Media
Enquiries
For media enquiries about Dr John-Paul Tung's areas of expertise, story ideas and help finding experts, contact our Media team: