Overview
Background
Professor Reade is Director of the Greater Brisbane Clinical School and Professor of Military Medicine and Surgery at UQ. The Greater Brisbane Clinical School comprises all the Brisbane teaching hospitals of the University of Queensland along with the preclinical teaching resources of the St Lucia campus and the General Practice Clinical Unit. A specialist intensive care physician, anaesthetist and clinician-researcher, he also leads a program of research relevant to military trauma medicine and surgery that holds equal promise for severely injured civilian trauma patients.
After clinical training in anaesthetics and intensive care medicine in Sydney, Melbourne, Oxford and Pittsburgh, a doctorate in the molecular pathogenesis of nitric oxide production in human septic shock from the University of Oxford and a postdoctoral research fellowship in clinical trials and epidemiology from the University of Pittsburgh, Michael returned to Australia as Associate Professor of Intensive Care Medicine at the Austin Hospital & the University of Melbourne in 2007. Michael held faculty appointments at the University of Oxford (where he taught physiology), the University of Pittsburgh (where he was an Instructor in critical care), and currently holds adjunct or honorary appointments at the University of London, the US Uniformed Services University of the Health Sciences, the University of Melbourne and Monash University. He has supervised postgraduate students in basic, applied and clinical research, and is a Fellow of the Higher Education Academy of the United Kingdom.
In parallel with his academic and clinical work, Michael served in the Australian Army Reserve until his appointment to the full-time ADF Chair in 2011. He was commissioned as a General Service Officer in the Australian Army in 1990, and prior to his appointment to UQ had deployed to Bosnia and Kosovo (on attachment to the British Airborne Brigade), Timor, the Solomon Islands and Afghanistan. In 2013 he commanded the Australian Specialist Health Group at the NATO ISAF Role 3 Hospital in Kandahar, Afghanistan, and in 2015 in Iraq he was the first Director of Clinical Services of the ADF hospital deployed in support of Operation Inherent Resolve. He deployed again to Iraq in 2016 and 2017. From 2015-2018 he was the Director of Clinical Services of the Australian Regular Army's only field hospital. In 2017 he led this unit to become the first ever ADF hospital accredited by the Royal Australasian College of Surgeons Trauma Verification Program. He was recognised for this service by appointment as a Member in the Military Division of the Order of Australia in the 2019 Queen's Birthday Honours List. From 2019-2022 on promotion to Brigadier he was appointed Director General Health Reserve - Army, responsible for technical regulation of specialist medical, nursing and allied health support. He remains a senior clinical advisor to Joint Health Command of the Australian Defence Force.
Professor Reade's clinical research focusses on treatments for exsanguinating haemorrhage, improving trauma systems, and preventing and treating acute cognitive impairment (such as that which results from traumatic brain injury). He is the Chief Investigator in an NHMRC-funded clinical trial of cyropreserved (frozen) platelets, a technology which holds equal promise to military and civilian trauma patients, particularly those in smaller hospitals. He is also a Chief Investigator in NHMRC-funded multicentre clinical trials of tranexamic acid and fibrinogen concentrate (drugs thought to reduce mortality from traumatic bleeding), the effect of erythropoietin on inflammation and mortality after severe trauma, a novel anti-delirium strategy for use in critically ill patients, and an advanced MRI/biomarker study in traumatic brain injury. He has active research collaborations with Australian Red Cross Lifeblood, the National Trauma Research Institute, the Australian and New Zealand Intensive Care Research Centre at Monash University, the ANZICS Clinical Trials Group and the ANZCA Clinical Trials Network.
Professor Reade is also developing a research programme focussed on trauma systems design, in collaboration with colleagues at the Jamieson Trauma Institute on the Royal Brisbane and Women's Hospital campus, Australian state ambulance services and the US and UK armed forces, aiming (for example) to optimise the allocation of prehospital and hospital resources in the management of life-threatening trauma.
Professor Reade currently supervises 10 postgraduate students (including 4 PhD students) and one postdoctoral research fellow, most of whom are Defence Force officers. He holds or has held research grants totalling >A$51M, has published >230 peer-reviewed papers and delivered >440 lectures at national and international conferences. From 2019-2021, Professor Reade was President of the Australasian Trauma Society.
Availability
- Professor Michael Reade is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, University of Sydney
- Bachelor of Medicine and Surgery and Medical Science, University of Sydney
- Doctor of Philosophy, University of Oxford
- Masters (Coursework) of Public Health, University of Pittsburgh
- Doctoral Diploma, University of Sydney
- Australian Institute of Company Directors, Australian Institute of Company Directors
- Australian and New Zealand College of Anaesthetists, Australian and New Zealand College of Anaesthetists
- College of Intensive Care Medicine, College of Intensive Care Medicine
- Fellow, Higher Education Academy, Higher Education Academy
- Associate Fellow, Royal Australasian College of Medical Administrators, Royal Australasian College of Medical Administrators
Research interests
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Trauma
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Haemorrhage
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Coagulopathy
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Trauma systems
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Delirium
Works
Search Professor Michael Reade’s works on UQ eSpace
2024
Journal Article
Diagnosis, prevention and management of delirium: spot it, stop it, treat it
Yoon, Isabel A., Galarneau, David, Winslow, Marlie, Park, Jacob, Mauricio, Adam X., Reade, Michael C. and Teodorczuk, Andrew (2024). Diagnosis, prevention and management of delirium: spot it, stop it, treat it. BJPsych Advances, 1-12. doi: 10.1192/bja.2024.57
2024
Journal Article
The nature of clinical research: even a clear answer gives rise to many other questions
Reade, Michael C. and Liu, David (2024). The nature of clinical research: even a clear answer gives rise to many other questions. Intensive Care Medicine, 1-2. doi: 10.1007/s00134-024-07711-1
2024
Journal Article
Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial
Liu, David, Hallt, Elizabeth, Platz, Alanna, Humblet, Alain, Lassig-Smith, Melissa, Stuart, Janine, Fourie, Cheryl, Livermore, Amelia, McConnochie, Bree-Yana, Starr, Therese, Herbst, Kymberley, Woods, Christine A., Pincus, Jason M. and Reade, Michael C. (2024). Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial. Intensive Care Medicine, 50 (11), 1873-1883. doi: 10.1007/s00134-024-07619-w
2024
Journal Article
Development of a quality indicator set for the optimal acute management of moderate to severe traumatic brain injury in the Australian context
Jeffcote, Toby, Battistuzzo, Camila R., Roach, Rebecca, Bell, Catherine, Bendinelli, Cino, Rashford, Stephen, Jithoo, Ron, Gabbe, Belinda J., Flower, Oliver, O’Reilly, Gerard, Campbell, Lewis T., Cooper, D. James, Balogh, Zsolt J., Udy, Andrew A., Westerlund, Torg, Withers, Teresa, O’Brien, Terence J., McGloughlin, Stephen, McNamara, Robert, Bellomo, Rinaldo, Cameron, Peter, Cooper, Paul David, Weeden, Mark, Waak, Michaela, Reade, Michael C. (Delphi panel), Plummer, Mark, Noonan, Michael, Fitzgerald, Melinda, Bihari, Shailesh ... Delphi panel (2024). Development of a quality indicator set for the optimal acute management of moderate to severe traumatic brain injury in the Australian context. Neurocritical Care. doi: 10.1007/s12028-024-02107-x
2024
Journal Article
The Australian Traumatic Brain Injury Initiative: Systematic Review of Clinical Factors Associated with Outcomes in People with Moderate-Severe Traumatic Brain Injury
McKimmie, Ancelin, Keeves, Jemma, Gadowski, Adelle, Bagg, Matthew K., Antonic-Baker, Ana, Hicks, Amelia J., Hill, Regina, Clarke, Nyssa, Holland, Andrew, Veitch, Bill, Fatovich, Daniel, Reeder, Sandy, Romero, Lorena, Ponsford, Jennie L., Lannin, Natasha A., O’Brien, Terence J., Cooper, D. Jamie, Rushworth, Nick, Fitzgerald, Melinda, Gabbe, Belinda J., Cameron, Peter A., Alexander, Tara, Anderson, Vicki, Armstrong, Elizabeth, Babl, Franz E., Balogh, Zsolt J., Barlow, Karen M., Bellapart, Judith, Bidargaddi, Niranjan ... Zeeman, Heidi (2024). The Australian Traumatic Brain Injury Initiative: Systematic Review of Clinical Factors Associated with Outcomes in People with Moderate-Severe Traumatic Brain Injury. Neurotrauma Reports, 5 (1), 640-659. doi: 10.1089/neur.2023.0111
2024
Journal Article
Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage
Milford, Elissa M., Gurney, Jennifer M., Beckett, Andrew, Strandenes, Geir and Reade, Michael C. (2024). Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage. Journal of Trauma and Acute Care Surgery, 97 (3), e23-e27. doi: 10.1097/ta.0000000000004369
2024
Journal Article
Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis
Ceric, Ameldina, Holgersson, Johan, May, Teresa L., Skrifvars, Markus B., Haestbacka, Johanna, Saxena, Manoj, Aneman, Anders, Delaney, Anthony, Reade, Michael C., Delcourt, Candice, Jakobsen, Janus Christian and Nielsen, Niklas (2024). Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis. Eclinicalmedicine, 71 102569, 1-12. doi: 10.1016/j.eclinm.2024.102569
2024
Journal Article
Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial
Aitken, Leanne M., Emerson, Lydia M., Kydonaki, Kalliopi, Blackwood, Bronagh, Creagh-Brown, Benedict, Lone, Nazir I., McKenzie, Cathrine A., Reade, Michael C., Weir, Christopher J., Wise, Matt P. and Walsh, Timothy S. (2024). Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial. BMJ Open, 14 (4) e081637, 1-7. doi: 10.1136/bmjopen-2023-081637
2024
Journal Article
The Australian Traumatic Brain Injury Initiative: Review and Recommendations for Outcome Measures for Use With Adults and Children After Moderate-to-Severe Traumatic Brain Injury
Ponsford, Jennie L., Hicks, Amelia J., Bagg, Matthew K., Phyland, Ruby, Carrier, Sarah, James, Amelia C., Lannin, Natasha A., Rushworth, Nick, O’Brien, Terence J., Cameron, Peter A., Cooper, D. Jamie, Hill, Regina, Gabbe, Belinda J., Fitzgerald, Melinda, Alexander, Tara, Anderson, Vicki, Antonic-Baker, Ana, Armstrong, Elizabeth, Babl, Franz E., Balogh, Zsolt J., Barlow, Karen M., Bellapart, Judith, Bidargaddi, Niranjan, Bosio, Erika, Bragge, Peter, Bynevelt, Michael, Caeyenberghs, Karen, Capell, Jacquelin, Chai, Kevin E.K. ... AUS-TBI Initiative Investigators (2024). The Australian Traumatic Brain Injury Initiative: Review and Recommendations for Outcome Measures for Use With Adults and Children After Moderate-to-Severe Traumatic Brain Injury. Neurotrauma Reports, 5 (1), 387-408. doi: 10.1089/neur.2023.0127
2024
Journal Article
Patient blood management guideline for adults with critical bleeding
Mitra, Biswadev, Jorgensen, Margaret, Reade, Michael C., Keegan, Anastazia, Holley, Anthony, Farmer, Shannon, Harvey, Nichole, Winearls, James, Parr, Michael, French, Craig J. and for the Clinical and Consumer Reference Group for the Update of Patient Blood Management Guidelines (Module 1: Critical Bleeding/Massive Transfusion) (2024). Patient blood management guideline for adults with critical bleeding. Medical Journal of Australia, 220 (4), 211-216. doi: 10.5694/mja2.52212
2024
Journal Article
Transforming research to improve therapies for trauma in the twenty-first century
Juffermans, Nicole P., Gozden, Tarik, Brohi, Karim, Davenport, Ross, Acker, Jason P., Reade, Michael C., Maegele, Marc, Neal, Matthew D. and Spinella, Philip C. (2024). Transforming research to improve therapies for trauma in the twenty-first century. Critical Care, 28 (1) 45. doi: 10.1186/s13054-024-04805-6
2024
Journal Article
PRECISION-TBI: a study protocol for a vanguard prospective cohort study to enhance understanding and management of moderate to severe traumatic brain injury in Australia
Jeffcote, Toby, Battistuzzo, Camila R, Plummer, Mark P, McNamara, Robert, Anstey, James, Bellapart, Judith, Roach, Rebecca, Chow, Andrew, Westerlund, Torgeir, Delaney, Anthony, Bihari, Shailesh, Bowen, David, Weeden, Mark, Trapani, Anthony, Reade, Michael, Jeffree, Rosalind L, Fitzgerald, Melinda, Gabbe, Belinda J, O'Brien, Terence J, Nichol, Alistair D, Cooper, D James, Bellomo, Rinaldo and Udy, Andrew (2024). PRECISION-TBI: a study protocol for a vanguard prospective cohort study to enhance understanding and management of moderate to severe traumatic brain injury in Australia. BMJ Open, 14 (2) e080614, 1-7. doi: 10.1136/bmjopen-2023-080614
2024
Journal Article
The Australian Traumatic Brain Injury Initiative: Systematic Review and Consensus Process to Determine the Predictive Value of Pre-existing Health Conditions for People with Moderate-Severe Traumatic Brain Injury
Antonic-Baker, Ana, Auvrez, Clarissa, Tao, Gerard, Bagg, Matthew K., Gadowski, Adelle, McKimmie, Ancelin, Hicks, Amelia J., Hill, Regina, Romero, Lorena, Ponsford, Jennie L., Lannin, Natasha A., Gabbe, Belinda J., Cameron, Peter A., Cooper, D. Jamie, Rushworth, Nick, Fitzgerald, Melinda, O'Brien, Terence J., Alexander, Tara, Anderson, Vicki, Armstrong, Elizabeth, Babl, Franz E., Balogh, Zsolt J., Barlow, Karen M., Bellapart, Judith, Bidargaddi, Niranjan, Bosio, Erika, Bragge, Peter, Bynevelt, Michael, Caeyenberghs, Karen ... Zeeman, Heidi (2024). The Australian Traumatic Brain Injury Initiative: Systematic Review and Consensus Process to Determine the Predictive Value of Pre-existing Health Conditions for People with Moderate-Severe Traumatic Brain Injury. Journal of Neurotrauma. doi: 10.1089/neu.2023.0462
2023
Journal Article
The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management
Tsigaras, Zac A., Weeden, Mark, McNamara, Robert, Jeffcote, Toby, Udy, Andrew A., Anstey, James, Plummer, Mark, Bellapart, Judith, Chow, Andrew, Delaney, Anthony, Bihari, Shailesh, Bowen, David, Reade, Michael, Jeffree, Lindy, Fitzgerald, Melinda, O'Brien, Terry, Nichol, Alistair, Bellomo, Rinaldo, Cooper, Jamie, Trapani, Tony and Battistuzzo, Camila (2023). The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management. Critical Care and Resuscitation, 25 (4), 229-236. doi: 10.1016/j.ccrj.2023.10.009
2023
Journal Article
Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK
Walsh, Timothy Simon, Aitken, Leanne M, McKenzie, Cathrine A, Boyd, Julia, Macdonald, Alix, Giddings, Annabel, Hope, David, Norrie, John, Weir, Christopher, Parker, Richard Anthony, Lone, Nazir I, Emerson, Lydia, Kydonaki, Kalliopi, Creagh-Brown, Benedict, Morris, Stephen, McAuley, Daniel Francis, Dark, Paul, Wise, Matt P, Gordon, Anthony C, Perkins, Gavin, Reade, Michael, Blackwood, Bronagh, MacLullich, Alasdair, Glen, Robert and Page, Valerie J (2023). Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK. BMJ Open, 13 (12) e078645, 1-11. doi: 10.1136/bmjopen-2023-078645
2023
Journal Article
Comment: Is off-label medication use in the ICU a problem?
Cotta, Menino O., Roberts, Jason A. and Reade, Michael C. (2023). Comment: Is off-label medication use in the ICU a problem?. Critical Care, 27 (1) 288, 288. doi: 10.1186/s13054-023-04546-y
2023
Journal Article
Transfusion practices in intensive care units: an Australian and New Zealand point prevalence study
Flint, Andrew W. J., Brady, Karina, Wood, Erica M., Thao, Le Thi Phuong, Hammond, Naomi, Knowles, Serena, Nangla, Conrad, Reade, Michael C. and McQuilten, Zoe K. (2023). Transfusion practices in intensive care units: an Australian and New Zealand point prevalence study. Critical Care and Resuscitation, 25 (4), 193-200. doi: 10.1016/j.ccrj.2023.10.006
2023
Journal Article
Natural language processing diagnosed behavioural disturbance phenotypes in the intensive care unit: characteristics, prevalence, trajectory, treatment, and outcomes
Young, Marcus, Holmes, Natasha E., Kishore, Kartik, Amjad, Sobia, Gaca, Michele, Serpa Neto, Ary, Reade, Michael C. and Bellomo, Rinaldo (2023). Natural language processing diagnosed behavioural disturbance phenotypes in the intensive care unit: characteristics, prevalence, trajectory, treatment, and outcomes. Critical Care, 27 (1) 425, 425. doi: 10.1186/s13054-023-04695-0
2023
Journal Article
Prehospital tranexamic acid for severe trauma
The PATCH-Trauma Investigators and the ANZICS Clinical Trials Group and Reade, Michael (2023). Prehospital tranexamic acid for severe trauma. New England Journal of Medicine, 389 (2), 127-136. doi: 10.1056/nejmoa2215457
2023
Journal Article
The Australian Delirium Clinical Care Standard: not just another brick in the wall
Teodorczuk, Andrew, Reade, Michael C. and Graham, Frederick A. (2023). The Australian Delirium Clinical Care Standard: not just another brick in the wall. Age and Ageing, 52 (6) afad078, 1-5. doi: 10.1093/ageing/afad078
Funding
Current funding
Supervision
Availability
- Professor Michael Reade is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The spatial epidemiology of trauma in Queensland
Principal Advisor
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Doctor Philosophy
Critical care management of burns patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Associate Professor Jeremy Cohen
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Doctor Philosophy
The role of bromodomain and extra-terminal domain (BET) containing protein inhibitors in a translational model of sepsis-induced myocardial dysfunction.
Associate Advisor
Other advisors: Associate Professor Jayesh Dhanani
Completed supervision
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2023
Doctor Philosophy
The role of the endothelial glycocalyx in severe trauma
Principal Advisor
Other advisors: Dr John-Paul Tung
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2016
Master Philosophy
Validation of Acute Traumatic Coagulopathy in an ovine model of trauma and haemorrhage
Principal Advisor
Other advisors: Professor John Fraser
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2020
Doctor Philosophy
Characterisation of immune responses to standard stored and cryopreserved blood components in sheep in vitro models of transfusion
Associate Advisor
Other advisors: Dr John-Paul Tung
Media
Enquiries
Contact Professor Michael Reade directly for media enquiries about:
- Intensive care medicine
- Medicine - military
- Medicine - trauma
- Military - medicine
- Trauma medicine and surgery
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