
Overview
Background
Professor Reade is Director of the Greater Brisbane Clinical School and Professor of Military Medicine and Surgery at UQ. The Greater Brisbane Clinical School comprises all the Brisbane teaching hospitals of the University of Queensland along with the preclinical teaching resources of the St Lucia campus and the General Practice Clinical Unit. A specialist intensive care physician, anaesthetist and clinician-researcher, he also leads a program of research relevant to military trauma medicine and surgery that holds equal promise for severely injured civilian trauma patients.
After clinical training in anaesthetics and intensive care medicine in Sydney, Melbourne, Oxford and Pittsburgh, a doctorate in the molecular pathogenesis of nitric oxide production in human septic shock from the University of Oxford and a postdoctoral research fellowship in clinical trials and epidemiology from the University of Pittsburgh, Michael returned to Australia as Associate Professor of Intensive Care Medicine at the Austin Hospital & the University of Melbourne in 2007. Michael held faculty appointments at the University of Oxford (where he taught physiology), the University of Pittsburgh (where he was an Instructor in critical care), and currently holds adjunct or honorary appointments at the University of London, the US Uniformed Services University of the Health Sciences, the University of Melbourne and Monash University. He has supervised postgraduate students in basic, applied and clinical research, and is a Fellow of the Higher Education Academy of the United Kingdom.
In parallel with his academic and clinical work, Michael served in the Australian Army Reserve until his appointment to the full-time ADF Chair in 2011. He was commissioned as a General Service Officer in the Australian Army in 1990, and prior to his appointment to UQ had deployed to Bosnia and Kosovo (on attachment to the British Airborne Brigade), Timor, the Solomon Islands and Afghanistan. In 2013 he commanded the Australian Specialist Health Group at the NATO ISAF Role 3 Hospital in Kandahar, Afghanistan, and in 2015 in Iraq he was the first Director of Clinical Services of the ADF hospital deployed in support of Operation Inherent Resolve. He deployed again to Iraq in 2016 and 2017. From 2015-2018 he was the Director of Clinical Services of the Australian Regular Army's only field hospital. In 2017 he led this unit to become the first ever ADF hospital accredited by the Royal Australasian College of Surgeons Trauma Verification Program. He was recognised for this service by appointment as a Member in the Military Division of the Order of Australia in the 2019 Queen's Birthday Honours List. From 2019-2022 on promotion to Brigadier he was appointed Director General Health Reserve - Army, responsible for technical regulation of specialist medical, nursing and allied health support. He remains a senior clinical advisor to Joint Health Command of the Australian Defence Force.
Professor Reade's clinical research focusses on treatments for exsanguinating haemorrhage, improving trauma systems, and preventing and treating acute cognitive impairment (such as that which results from traumatic brain injury). He is the Chief Investigator in an NHMRC-funded clinical trial of cyropreserved (frozen) platelets, a technology which holds equal promise to military and civilian trauma patients, particularly those in smaller hospitals. He is also a Chief Investigator in NHMRC-funded multicentre clinical trials of tranexamic acid and fibrinogen concentrate (drugs thought to reduce mortality from traumatic bleeding), the effect of erythropoietin on inflammation and mortality after severe trauma, a novel anti-delirium strategy for use in critically ill patients, and an advanced MRI/biomarker study in traumatic brain injury. He has active research collaborations with Australian Red Cross Lifeblood, the National Trauma Research Institute, the Australian and New Zealand Intensive Care Research Centre at Monash University, the ANZICS Clinical Trials Group and the ANZCA Clinical Trials Network.
Professor Reade is also developing a research programme focussed on trauma systems design, in collaboration with colleagues at the Jamieson Trauma Institute on the Royal Brisbane and Women's Hospital campus, Australian state ambulance services and the US and UK armed forces, aiming (for example) to optimise the allocation of prehospital and hospital resources in the management of life-threatening trauma.
Professor Reade currently supervises 10 postgraduate students (including 4 PhD students) and one postdoctoral research fellow, most of whom are Defence Force officers. He holds or has held research grants totalling >A$51M, has published >230 peer-reviewed papers and delivered >440 lectures at national and international conferences. From 2019-2021, Professor Reade was President of the Australasian Trauma Society.
Availability
- Professor Michael Reade is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, University of Sydney
- Bachelor of Medicine and Surgery and Medical Science, University of Sydney
- Doctor of Philosophy, University of Oxford
- Masters (Coursework) of Public Health, University of Pittsburgh
- Doctoral Diploma, University of Sydney
- Australian Institute of Company Directors, Australian Institute of Company Directors
- Australian and New Zealand College of Anaesthetists, Australian and New Zealand College of Anaesthetists
- College of Intensive Care Medicine, College of Intensive Care Medicine
- Fellow, Higher Education Academy, Higher Education Academy
- Associate Fellow, Royal Australasian College of Medical Administrators, Royal Australasian College of Medical Administrators
Research interests
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Trauma
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Haemorrhage
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Coagulopathy
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Trauma systems
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Delirium
Works
Search Professor Michael Reade’s works on UQ eSpace
2023
Journal Article
Transfusion practices in intensive care units: an Australian and New Zealand point prevalence study
Flint, Andrew W. J., Brady, Karina, Wood, Erica M., Thao, Le Thi Phuong, Hammond, Naomi, Knowles, Serena, Nangla, Conrad, Reade, Michael C. and McQuilten, Zoe K. (2023). Transfusion practices in intensive care units: an Australian and New Zealand point prevalence study. Critical Care and Resuscitation, 25 (4), 193-200. doi: 10.1016/j.ccrj.2023.10.006
2023
Journal Article
Natural language processing diagnosed behavioural disturbance phenotypes in the intensive care unit: characteristics, prevalence, trajectory, treatment, and outcomes
Young, Marcus, Holmes, Natasha E., Kishore, Kartik, Amjad, Sobia, Gaca, Michele, Serpa Neto, Ary, Reade, Michael C. and Bellomo, Rinaldo (2023). Natural language processing diagnosed behavioural disturbance phenotypes in the intensive care unit: characteristics, prevalence, trajectory, treatment, and outcomes. Critical Care, 27 (1) 425, 425. doi: 10.1186/s13054-023-04695-0
2023
Journal Article
Prehospital tranexamic acid for severe trauma
The PATCH-Trauma Investigators and the ANZICS Clinical Trials Group and Reade, Michael (2023). Prehospital tranexamic acid for severe trauma. New England Journal of Medicine, 389 (2), 127-136. doi: 10.1056/nejmoa2215457
2023
Journal Article
The Australian Delirium Clinical Care Standard: not just another brick in the wall
Teodorczuk, Andrew, Reade, Michael C. and Graham, Frederick A. (2023). The Australian Delirium Clinical Care Standard: not just another brick in the wall. Age and Ageing, 52 (6) afad078, 1-5. doi: 10.1093/ageing/afad078
2023
Journal Article
Whose side are you on? Complexities arising from the non-combatant status of military medical personnel
Reade, Michael C. (2023). Whose side are you on? Complexities arising from the non-combatant status of military medical personnel. Monash Bioethics Review, 41 (1), 67-86. doi: 10.1007/s40592-022-00168-2
2023
Journal Article
Australian Defence Force Global Health Engagement through malaria and other vectorborne disease programmes in the Pacific and Southeast Asia
Reade, Michael Charles, Auliff, A., McPherson, B. and Edstein, M. (2023). Australian Defence Force Global Health Engagement through malaria and other vectorborne disease programmes in the Pacific and Southeast Asia. BMJ Military Health, 170 (e1) e002335, 1-6. doi: 10.1136/military-2022-002335
2023
Journal Article
Delayed tracheoesophageal fistula and refractory respiratory failure caused by inhalation burns and emergency venovenous ECMO to facilitate its management: a case report
Dhanani, Jayesh, Pincus, Jason, Townsend, Shane, Pang, George, Vujcich, Elizabeth, Windsor, Morgan and Reade, Michael C. (2023). Delayed tracheoesophageal fistula and refractory respiratory failure caused by inhalation burns and emergency venovenous ECMO to facilitate its management: a case report. Journal of Burn Care and Research, 44 (3), 734-739. doi: 10.1093/jbcr/irad040
2023
Journal Article
Pre‐hospital freeze‐dried plasma for critical bleeding after trauma: a pilot randomized controlled trial
Mitra, Biswadev, Meadley, Ben, Bernard, Stephen, Maegele, Marc, Gruen, Russell L., Bradley, Olivia, Wood, Erica M., McQuilten, Zoe K., Fitzgerald, Mark, St. Clair, Toby, Webb, Andrew, Anderson, David and Reade, Michael C. (2023). Pre‐hospital freeze‐dried plasma for critical bleeding after trauma: a pilot randomized controlled trial. Academic Emergency Medicine, 30 (10), 1013-1019. doi: 10.1111/acem.14745
2023
Journal Article
PREdiction and Diagnosis using Imaging and Clinical biomarkers Trial in Traumatic Brain Injury (PREDICT-TBI) study protocol: an observational, prospective, multicentre cohort study for the prediction of outcome in moderate-to-severe TBI
Nasrallah, Fatima, Bellapart, Judith, Walsham, James, Jacobson, Esther, To, Xuan Vinh, Manzanero, Silvia, Brown, Nathan, Meyer, Jason, Stuart, Janine, Evans, Tracey, Chandra, Shekhar S., Ross, Jason, Campbell, Lewis, Senthuran, Siva, Newcombe, Virginia, McCullough, James, Fleming, Jennifer, Pollard, Clifford and Reade, Michael (2023). PREdiction and Diagnosis using Imaging and Clinical biomarkers Trial in Traumatic Brain Injury (PREDICT-TBI) study protocol: an observational, prospective, multicentre cohort study for the prediction of outcome in moderate-to-severe TBI. BMJ Open, 13 (4) e067740, 1-9. doi: 10.1136/bmjopen-2022-067740
2023
Journal Article
Experiences of medical practitioners in the Australian Defence Force on live tissue trauma training
Mahoney, Adam, Reade, M. C. and Moffat, M. (2023). Experiences of medical practitioners in the Australian Defence Force on live tissue trauma training. BMJ Military Health, 169 (2) 001550, 122-126. doi: 10.1136/bmjmilitary-2020-001550
2023
Journal Article
Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. Data from the SYNAPSE-ICU study
Robba, Chiara, Graziano, Francesca, Guglielmi, Angelo, Rebora, Paola, Galimberti, Stefania, Taccone, Fabio S., Citerio, Giuseppe, Videtta, Walter, Domeniconi, Gustavo, Giménez, María Estrella, Fumale, Mariela, Amundarain, Edgar Daniel, Casanova, Matias, Reade, Michael, Hallt, Elizabeth, Pearson, David, Seppelt, Ian, Helbok, Raimund, Davidovich, Valery, Meyfroidt, Geert, Crippa, Ilaria Alice, Mebis, Liese, Biston, Patrick, Van De Velde, Stijn, Denis, Glorieux, Kurtz, Pedro, Wayhs, Samia Yasin, Sekhon, Mypinder, Griesdale, Donald ... Olson, Daiwai (2023). Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. Data from the SYNAPSE-ICU study. Intensive Care Medicine, 49 (1), 50-61. doi: 10.1007/s00134-022-06937-1
2023
Book Chapter
The Most Important Questions in the Current Practice of Transfusion of Critically Bleeding Patients
Flint, A. W., Winearls, J. and Reade, M. C. (2023). The Most Important Questions in the Current Practice of Transfusion of Critically Bleeding Patients. Annual Update in Intensive Care and Emergency Medicine 2023. (pp. 339-353) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-23005-9_25
2022
Journal Article
Perspective: the top 11 priorities to improve trauma outcomes, from system to patient level
Reade, Michael C. (2022). Perspective: the top 11 priorities to improve trauma outcomes, from system to patient level. Critical Care, 26 (1) 395, 1-8. doi: 10.1186/s13054-022-04243-2
2022
Journal Article
Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials)
Reade, Michael C., Marks, Denese C, Howe, Belinda, McGuinness, Shay, Parke, Rachael, Navarra, Leanlove, Charlewood, Richard, Johnson, Lacey and McQuilten, Zoe (2022). Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials). BMJ Open, 12 (12) e068933, 1-12. doi: 10.1136/bmjopen-2022-068933
2022
Journal Article
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients
Moore, John P. R., Shehabi, Yahya, Reade, Michael C., Bailey, Michael, Fraser, John F., Murray, Lauren, Anstey, Christopher and Singer, Mervyn (2022). Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients. Critical Care, 26 (1) 359, 1-10. doi: 10.1186/s13054-022-04237-0
2022
Journal Article
Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III)
Shehabi, Yahya, Serpa Neto, Ary, Bellomo, Rinaldo, Howe, Belinda D., Arabi, Yaseen M., Bailey, Michael, Bass, Frances E., Bin Kadiman, Suhaini, McArthur, Colin J., Reade, Michael C., Seppelt, Ian M., Takala, Jukka, Wise, Matt P., Webb, Steve A. and SPICE III study investigators (2022). Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III). American Journal of Respiratory and Critical Care Medicine, 207 (7), 876-886. doi: 10.1164/rccm.202206-1208OC
2022
Journal Article
Level of sedation in critically ill adult patients: a protocol for a systematic review with meta-analysis and trial sequential analysis
Ceric, Ameldina, Holgersson, Johan, May, Teresa, Skrifvars, Markus B., Hästbacka, Johanna, Saxena, Manoj, Aneman, Anders, Delaney, Anthony, Reade, Michael C., Delcourt, Candice, Jakobsen, Janus and Nielsen, Niklas (2022). Level of sedation in critically ill adult patients: a protocol for a systematic review with meta-analysis and trial sequential analysis. BMJ Open, 12 (9) e061806, 1-9. doi: 10.1136/bmjopen-2022-061806
2022
Journal Article
Fingolimod does not prevent syndecan-4 shedding from the endothelial glycocalyx in a cultured human umbilical vein endothelial cell model of vascular injury
Milford, Elissa M., Meital, Lara, Kuballa, Anna, Reade, Michael C. and Russell, Fraser D. (2022). Fingolimod does not prevent syndecan-4 shedding from the endothelial glycocalyx in a cultured human umbilical vein endothelial cell model of vascular injury. Intensive Care Medicine Experimental, 10 (1) 34, 34. doi: 10.1186/s40635-022-00462-7
2022
Journal Article
A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit
Wiebe, Jordan, Lipman, Jeffrey and Reade, Michael C. (2022). A point-prevalence study of off-label medication use in an Australian adult tertiary intensive care unit. Critical Care and Resuscitation, 24 (2), 183-187. doi: 10.51893/2022.2.OA8
2022
Journal Article
Transfusion-related acute lung injury (TRALI): potential pathways of development, strategies for prevention and treatment, and future research directions
Tung, John-Paul, Chiaretti, Sara, Dean, Melinda M., Sultana, Annette J., Reade, Michael C. and Fung, Yoke Lin (2022). Transfusion-related acute lung injury (TRALI): potential pathways of development, strategies for prevention and treatment, and future research directions. Blood Reviews, 53 100926, 100926. doi: 10.1016/j.blre.2021.100926
Funding
Current funding
Supervision
Availability
- Professor Michael Reade is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Critical care management of burns patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Associate Professor Jeremy Cohen
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Doctor Philosophy
The spatial epidemiology of trauma in Queensland
Principal Advisor
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Doctor Philosophy
The role of bromodomain and extra-terminal domain (BET) containing protein inhibitors in a translational model of sepsis-induced myocardial dysfunction.
Associate Advisor
Other advisors: Associate Professor Jayesh Dhanani
Completed supervision
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2016
Master Philosophy
Validation of Acute Traumatic Coagulopathy in an ovine model of trauma and haemorrhage
Principal Advisor
Other advisors: Professor John Fraser
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2020
Doctor Philosophy
Characterisation of immune responses to standard stored and cryopreserved blood components in sheep in vitro models of transfusion
Associate Advisor
Media
Enquiries
Contact Professor Michael Reade directly for media enquiries about:
- Intensive care medicine
- Medicine - military
- Medicine - trauma
- Military - medicine
- Trauma medicine and surgery
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