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2025

Journal Article

High ratio of plasma to red cells in contemporary resuscitation of haemorrhagic shock after trauma: a secondary analysis of the PATCH-trauma trial

Mitra, Biswadev, Reade, Michael C., Bernard, Steve, Dicker, Bridget, Maegele, Marc and Gruen, Russell L. (2025). High ratio of plasma to red cells in contemporary resuscitation of haemorrhagic shock after trauma: a secondary analysis of the PATCH-trauma trial. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 33 (1) 154. doi: 10.1186/s13049-025-01476-2

High ratio of plasma to red cells in contemporary resuscitation of haemorrhagic shock after trauma: a secondary analysis of the PATCH-trauma trial

2025

Journal Article

Sedation Practice in Intensive Care Evaluation, SPICE and beyond, Rinaldo’s legacy in sedation and delirium research

Shehabi, Yahya and Reade, Michael C. (2025). Sedation Practice in Intensive Care Evaluation, SPICE and beyond, Rinaldo’s legacy in sedation and delirium research. Critical Care and Resuscitation, 27 (3) 100142, 100142. doi: 10.1016/j.ccrj.2025.100142

Sedation Practice in Intensive Care Evaluation, SPICE and beyond, Rinaldo’s legacy in sedation and delirium research

2025

Journal Article

Platelet dysfunction in trauma: a sub study of the FEISTY pilot trial analysing whole blood aggregometry data

Durkin, Zachary J, Whebell, Stephen F, Wullschleger, Martin, McCullough, James, Czuchwicki, Sarah, Wake, Elizabeth, Reade, Michael C and Winearls, James (2025). Platelet dysfunction in trauma: a sub study of the FEISTY pilot trial analysing whole blood aggregometry data. Injury, 56 (8) 112468, 112468-8. doi: 10.1016/j.injury.2025.112468

Platelet dysfunction in trauma: a sub study of the FEISTY pilot trial analysing whole blood aggregometry data

2025

Journal Article

Tranexamic acid did not attenuate the acute rise in plasma syndecan-1 in a severely injured cohort: a laboratory analysis of the PATCH clinical trial

Milford, Elissa M., Marjanovic, Dusan, Ho, Heidi, Wallis, Steven, Draxler, Dominik F., Mitra, Biswadev, Gruen, Russell L., Medcalf, Robert, Bernard, Stephen, McArthur, Colin, Meagele, Marc, Burns, Brian, Gantner, Dashiell and Reade, Michael C. (2025). Tranexamic acid did not attenuate the acute rise in plasma syndecan-1 in a severely injured cohort: a laboratory analysis of the PATCH clinical trial. Intensive Care Medicine Experimental, 13 (1) 72, 72-1. doi: 10.1186/s40635-025-00784-2

Tranexamic acid did not attenuate the acute rise in plasma syndecan-1 in a severely injured cohort: a laboratory analysis of the PATCH clinical trial

2025

Journal Article

Lower fluid resuscitation volumes in the first 24 hours following a severe burn injury are independently associated with greater days alive and out of hospital: A retrospective cohort study

Gardiner, Ben, Coles, Victoria, Vujcich, Elizabeth, Reade, Michael C, Karamujic, Nermin and Milford, Elissa M (2025). Lower fluid resuscitation volumes in the first 24 hours following a severe burn injury are independently associated with greater days alive and out of hospital: A retrospective cohort study. Burns, 51 (8) 107610, 107610-8. doi: 10.1016/j.burns.2025.107610

Lower fluid resuscitation volumes in the first 24 hours following a severe burn injury are independently associated with greater days alive and out of hospital: A retrospective cohort study

2025

Journal Article

Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (<scp>MAP</scp>‐<scp>CARE</scp>): A protocol for a randomized clinical trial

Niemelä, V. H., Reinikainen, M., Nielsen, N., Bass, F., Young, P., Lilja, G., Dankiewicz, J., Hammond, N., Hästbacka, J., Levin, H., Moseby‐Knappe, M., Saxena, M., Tiainen, M., Ceric, A., Holgersson, J., Kamp, C. B., Tirkkonen, J., Oksanen, T., Kaakinen, T., Bendel, S., Düring, J., Lybeck, A., Johnsson, J., Unden, J., Lundin, A., Kåhlin, J., Grip, J., Lotman, E., Romundstad, L. ... Skrifvars, M. B. (2025). Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP‐CARE): A protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (6) e70040. doi: 10.1111/aas.70040

Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (<scp>MAP</scp>‐<scp>CARE</scp>): A protocol for a randomized clinical trial

2025

Journal Article

Fever management with or without a temperature control device after out‐of‐hospital cardiac arrest and resuscitation (TEMP‐CARE): A study protocol for a randomized clinical trial

Holgersson, Johan, Niemelä, V., Skrifvars, M. B., Kamp‐Jorgensen, C., Saxena, M., Young, P., Bass, F., Dankiewicz, J., Hammond, N., Hästbacka, J., Levin, H., Lilja, G., Moseby‐Knappe, M., Tiainen, M., Reinikainen, M., Ceric, A., Düring, J., Lybeck, A., Rodriguez‐Santos, D., Johnsson, J., Unden, J., Lundin, A., Kåhlin, J., Grip, J., Rosell, J., Lotman, E. M., Navarra, L., Crichton, B., Knight, D. ... Nielsen, N. (2025). Fever management with or without a temperature control device after out‐of‐hospital cardiac arrest and resuscitation (TEMP‐CARE): A study protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (5) e70034, 1-12. doi: 10.1111/aas.70034

Fever management with or without a temperature control device after out‐of‐hospital cardiac arrest and resuscitation (TEMP‐CARE): A study protocol for a randomized clinical trial

2025

Journal Article

Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial

Ceric, A., Dankiewicz, J., Hästbacka, J., Young, P., Niemelä, V. H., Bass, F., Skrifvars, M. B., Hammond, N., Saxena, M., Levin, H., Lilja, G., Moseby-Knappe, M., Tiainen, M., Reinikainen, M., Holgersson, J., Kamp, C. B., Wise, M. P., McGuigan, P. J., White, J., Sweet, K., Keeble, T. R., Glover, G., Hopkins, P., Remmington, C., Cole, J. M., Gorgoraptis, N., Pogson, D. G., Jackson, P., Düring, J. ... Nielsen, N. (2025). Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (5) e70022, 1-13. doi: 10.1111/aas.70022

Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial

2025

Journal Article

Sedation, temperature and pressure after cardiac arrest and resuscitation—The STEPCARE trial: A statistical analysis plan

Kamp, C. B., Dankiewicz, J., Harboe Olsen, M., Holgersson, J., Saxena, M., Young, P., Niemelä, V. H., Hästbacka, J., Levin, H., Lilja, G., Moseby-Knappe, M., Tiainen, M., Reinikainen, M., Ceric, A., Johnsson, J., Undén, J., Düring, J., Lybeck, A., Rodriguez-Santos, D., Lundin, A., Kåhlin, J., Grip, J., Lotman, E., Romundstad, L., Seidel, P., Stammet, P., Graf, T., Mengel, A., Leithner, C. ... Jakobsen, J. C. (2025). Sedation, temperature and pressure after cardiac arrest and resuscitation—The STEPCARE trial: A statistical analysis plan. Acta Anaesthesiologica Scandinavica, 69 (5) e70033, 1-9. doi: 10.1111/aas.70033

Sedation, temperature and pressure after cardiac arrest and resuscitation—The STEPCARE trial: A statistical analysis plan

2025

Journal Article

Coagulation factors in spray‐dried plasma: A systematic review and meta‐analysis

Mitra, Biswadev, Biggins, Patrick J. C., Marks, Denese C. and Reade, Michael C. (2025). Coagulation factors in spray‐dried plasma: A systematic review and meta‐analysis. Transfusion, 65 (5), 1012-1020. doi: 10.1111/trf.18255

Coagulation factors in spray‐dried plasma: A systematic review and meta‐analysis

2025

Conference Publication

Lower fluid resuscitation volumes in the first 24 hours following a severe burn injury are independently associated with greater days alive and out of hospital censored at day 90

Gardiner, Benjamin, Coles, Victoria, Vujcich, Elizabeth, Reade, Micheal, Lisec, Carl and Milford, Elissa (2025). Lower fluid resuscitation volumes in the first 24 hours following a severe burn injury are independently associated with greater days alive and out of hospital censored at day 90. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting 2025, Christchurch, New Zealand, 9-11 April 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2025.101333

Lower fluid resuscitation volumes in the first 24 hours following a severe burn injury are independently associated with greater days alive and out of hospital censored at day 90

2025

Conference Publication

Platelet transfusions in the intensive care unit: where evidence does not support practice

Flint, Andrew, McQuilten, Zoe, Reade, Michael and Wood, Erica (2025). Platelet transfusions in the intensive care unit: where evidence does not support practice. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting, Christchurch, New Zealand, 9-11 April 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2025.101332

Platelet transfusions in the intensive care unit: where evidence does not support practice

2025

Journal Article

The impact of red blood cells storage duration on the development of acute kidney injury: A secondary analysis of the TRANSFUSE multicenter randomized controlled trial

Aubron, Cécile, Moore, Elizabeth M., Ady, Bridget, Paul, Eldho, Kaukonen, Maija, Murray, Lynne, Barrett, Jonathan, Bailey, Matthew, Bowles, Timothy, Kelly, Sean, Cattigan, Claire, Cooper, David, Ernest, David, Evans, David, Fletcher, Jason, French, Craig, Gattas, David, Ghelani, Dhaval, Henderson, Seton, Kazemi, Alex, King, Bruce, Kruger, Peter, Liang, Janet, MacIsaac, Christopher, McArthur, Colin, Nichol, Alistair, Peake, Sandra, Reade, Michael C., Richards, Brent ... McQuilten, Zoe K. (2025). The impact of red blood cells storage duration on the development of acute kidney injury: A secondary analysis of the TRANSFUSE multicenter randomized controlled trial. Transfusion, 65 (5), 876-885. doi: 10.1111/trf.18230

The impact of red blood cells storage duration on the development of acute kidney injury: A secondary analysis of the TRANSFUSE multicenter randomized controlled trial

2025

Journal Article

Blood transfusion practices in intensive care: a prospective observational binational study

Flint, Andrew W. J., Poole, Alexis, Raasveld, Senta Jorinde, Bailey, Michael, Brady, Karina, Chen, Pin-Yen, Chen, Yan, Cooper, D. Jamie, French, Craig, Higgins, Alisa, Irving, Adam H., McAllister, Richard E., Neto, Ary Serpa, Trapani, Tony, Waters, Neil, Winearls, James, Reade, Michael C., Wood, Erica M., Vlaar, Alexander P. J. and McQuilten, Zoe K. (2025). Blood transfusion practices in intensive care: a prospective observational binational study. Critical Care Explorations, 7 (3) e1197. doi: 10.1097/cce.0000000000001197

Blood transfusion practices in intensive care: a prospective observational binational study

2025

Journal Article

The value of pilot trials in studies of postoperative sedation in critical care

Reade, Michael C. and Liu, David (2025). The value of pilot trials in studies of postoperative sedation in critical care. Intensive Care Medicine, 51 (3). doi: 10.1007/s00134-025-07814-3

The value of pilot trials in studies of postoperative sedation in critical care

2025

Journal Article

Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial

Walsh, Timothy S., Parker, Richard A., Aitken, Leanne M., McKenzie, Cathrine A., Emerson, Lydia, Boyd, Julia, MacDonald, Alix, Beveridge, Gayle, Giddings, Annabel, Hope, David, Irvine, Sîan, Tuck, Sharon, Lone, Nazir I., Kydonaki, Kalliopi, Norrie, John, Brealey, David, Antcliffe, David, Reay, Michael, Williams, Alan, Bewley, Jeremy, Creagh-Brown, Benedict, McAuley, Daniel F., Dark, Paul, Wise, Matt P., Gordon, Anthony C., Perkins, Gavin D., Reade, Michael C., Blackwood, Bronagh, MacLullich, Alasdair ... Weir, Christopher J. (2025). Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial. JAMA, 334 (1), 32-45. doi: 10.1001/jama.2025.7200

Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients: The A2B Randomized Clinical Trial

2024

Journal Article

The nature of clinical research: even a clear answer gives rise to many other questions

Reade, Michael C. and Liu, David (2024). The nature of clinical research: even a clear answer gives rise to many other questions. Intensive Care Medicine, 51 (1), 211-212. doi: 10.1007/s00134-024-07711-1

The nature of clinical research: even a clear answer gives rise to many other questions

2024

Journal Article

Diagnosis, prevention and management of delirium: spot it, stop it, treat it

Yoon, Isabel A., Galarneau, David, Winslow, Marlie, Park, Jacob, Mauricio, Adam X., Reade, Michael C. and Teodorczuk, Andrew (2024). Diagnosis, prevention and management of delirium: spot it, stop it, treat it. BJPsych Advances, 31 (6), 331-342. doi: 10.1192/bja.2024.57

Diagnosis, prevention and management of delirium: spot it, stop it, treat it

2024

Journal Article

Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial

Liu, David, Hallt, Elizabeth, Platz, Alanna, Humblet, Alain, Lassig-Smith, Melissa, Stuart, Janine, Fourie, Cheryl, Livermore, Amelia, McConnochie, Bree-Yana, Starr, Therese, Herbst, Kymberley, Woods, Christine A., Pincus, Jason M. and Reade, Michael C. (2024). Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial. Intensive Care Medicine, 50 (11), 1873-1883. doi: 10.1007/s00134-024-07619-w

Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial

2024

Journal Article

Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage

Milford, Elissa M., Gurney, Jennifer M., Beckett, Andrew, Strandenes, Geir and Reade, Michael C. (2024). Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage. Journal of Trauma and Acute Care Surgery, 97 (3), e23-e27. doi: 10.1097/ta.0000000000004369

Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage