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2025

Journal Article

Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial

Ceric, A., Dankiewicz, J., Hästbacka, J., Young, P., Niemelä, V. H., Bass, F., Skrifvars, M. B., Hammond, N., Saxena, M., Levin, H., Lilja, G., Moseby-Knappe, M., Tiainen, M., Reinikainen, M., Holgersson, J., Kamp, C. B., Wise, M. P., McGuigan, P. J., White, J., Sweet, K., Keeble, T. R., Glover, G., Hopkins, P., Remmington, C., Cole, J. M., Gorgoraptis, N., Pogson, D. G., Jackson, P., Düring, J. ... Nielsen, N. (2025). Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial. Acta Anaesthesiologica Scandinavica, 69 (5) e70022. doi: 10.1111/aas.70022

Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial

2025

Journal Article

The impact of red blood cells storage duration on the development of acute kidney injury: A secondary analysis of the <scp>TRANSFUSE</scp> multicenter randomized controlled trial

Aubron, Cécile, Moore, Elizabeth M., Ady, Bridget, Paul, Eldho, Kaukonen, Maija, Murray, Lynne, Barrett, Jonathan, Bailey, Matthew, Bowles, Timothy, Kelly, Sean, Cattigan, Claire, Cooper, David, Ernest, David, Evans, David, Fletcher, Jason, French, Craig, Gattas, David, Ghelani, Dhaval, Henderson, Seton, Kazemi, Alex, King, Bruce, Kruger, Peter, Liang, Janet, MacIsaac, Christopher, McArthur, Colin, Nichol, Alistair, Peake, Sandra, Reade, Michael C., Richards, Brent ... McQuilten, Zoe K. (2025). The impact of red blood cells storage duration on the development of acute kidney injury: A secondary analysis of the TRANSFUSE multicenter randomized controlled trial. Transfusion. doi: 10.1111/trf.18230

The impact of red blood cells storage duration on the development of acute kidney injury: A secondary analysis of the <scp>TRANSFUSE</scp> multicenter randomized controlled trial

2025

Journal Article

Blood Transfusion Practices in Intensive Care: A Prospective Observational Binational Study

Flint, Andrew W. J., Poole, Alexis, Raasveld, Senta Jorinde, Bailey, Michael, Brady, Karina, Chen, Pin-Yen, Chen, Yan, Cooper, D. Jamie, French, Craig, Higgins, Alisa, Irving, Adam H., McAllister, Richard E., Neto, Ary Serpa, Trapani, Tony, Waters, Neil, Winearls, James, Reade, Michael C., Wood, Erica M., Vlaar, Alexander P. J. and McQuilten, Zoe K. (2025). Blood Transfusion Practices in Intensive Care: A Prospective Observational Binational Study. Critical Care Explorations, 7 (3) e1197, e1197-3. doi: 10.1097/cce.0000000000001197

Blood Transfusion Practices in Intensive Care: A Prospective Observational Binational Study

2025

Journal Article

The value of pilot trials in studies of postoperative sedation in critical care

Reade, Michael C. and Liu, David (2025). The value of pilot trials in studies of postoperative sedation in critical care. Intensive Care Medicine, 1-2. doi: 10.1007/s00134-025-07814-3

The value of pilot trials in studies of postoperative sedation in critical care

2024

Journal Article

The nature of clinical research: even a clear answer gives rise to many other questions

Reade, Michael C. and Liu, David (2024). The nature of clinical research: even a clear answer gives rise to many other questions. Intensive Care Medicine, 51 (1), 1-2. doi: 10.1007/s00134-024-07711-1

The nature of clinical research: even a clear answer gives rise to many other questions

2024

Journal Article

Diagnosis, prevention and management of delirium: spot it, stop it, treat it

Yoon, Isabel A., Galarneau, David, Winslow, Marlie, Park, Jacob, Mauricio, Adam X., Reade, Michael C. and Teodorczuk, Andrew (2024). Diagnosis, prevention and management of delirium: spot it, stop it, treat it. BJPsych Advances, 1-12. doi: 10.1192/bja.2024.57

Diagnosis, prevention and management of delirium: spot it, stop it, treat it

2024

Journal Article

Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial

Liu, David, Hallt, Elizabeth, Platz, Alanna, Humblet, Alain, Lassig-Smith, Melissa, Stuart, Janine, Fourie, Cheryl, Livermore, Amelia, McConnochie, Bree-Yana, Starr, Therese, Herbst, Kymberley, Woods, Christine A., Pincus, Jason M. and Reade, Michael C. (2024). Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial. Intensive Care Medicine, 50 (11), 1873-1883. doi: 10.1007/s00134-024-07619-w

Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial

2024

Journal Article

Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage

Milford, Elissa M., Gurney, Jennifer M., Beckett, Andrew, Strandenes, Geir and Reade, Michael C. (2024). Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage. Journal of Trauma and Acute Care Surgery, 97 (3), e23-e27. doi: 10.1097/ta.0000000000004369

Type-specific whole blood still has a role in the era of low titer O universal donor transfusion for severe trauma hemorrhage

2024

Journal Article

Development of a quality indicator set for the optimal acute management of moderate to severe traumatic brain injury in the Australian context

Jeffcote, Toby, Battistuzzo, Camila R., Roach, Rebecca, Bell, Catherine, Bendinelli, Cino, Rashford, Stephen, Jithoo, Ron, Gabbe, Belinda J., Flower, Oliver, O’Reilly, Gerard, Campbell, Lewis T., Cooper, D. James, Balogh, Zsolt J., Udy, Andrew A., Westerlund, Torg, Withers, Teresa, O’Brien, Terence J., McGloughlin, Stephen, McNamara, Robert, Bellomo, Rinaldo, Cameron, Peter, Cooper, Paul David, Weeden, Mark, Waak, Michaela, Reade, Michael C. (Delphi panel), Plummer, Mark, Noonan, Michael, Fitzgerald, Melinda, Bihari, Shailesh ... Delphi panel (2024). Development of a quality indicator set for the optimal acute management of moderate to severe traumatic brain injury in the Australian context. Neurocritical Care, 42 (2) e11225, 485-494. doi: 10.1007/s12028-024-02107-x

Development of a quality indicator set for the optimal acute management of moderate to severe traumatic brain injury in the Australian context

2024

Journal Article

The Australian Traumatic Brain Injury Initiative: systematic review of clinical factors associated with outcomes in people with moderate-severe traumatic brain injury

McKimmie, Ancelin, Keeves, Jemma, Gadowski, Adelle, Bagg, Matthew K., Antonic-Baker, Ana, Hicks, Amelia J., Hill, Regina, Clarke, Nyssa, Holland, Andrew, Veitch, Bill, Fatovich, Daniel, Reeder, Sandy, Romero, Lorena, Ponsford, Jennie L., Lannin, Natasha A., O’Brien, Terence J., Cooper, D. Jamie, Rushworth, Nick, Fitzgerald, Melinda, Gabbe, Belinda J., Cameron, Peter A., Alexander, Tara, Anderson, Vicki, Armstrong, Elizabeth, Babl, Franz E., Balogh, Zsolt J., Barlow, Karen M. (AUS-TBI Investigators member), Bellapart, Judith, Bidargaddi, Niranjan ... Zeeman, Heidi (2024). The Australian Traumatic Brain Injury Initiative: systematic review of clinical factors associated with outcomes in people with moderate-severe traumatic brain injury. Neurotrauma Reports, 5 (1), 640-659. doi: 10.1089/neur.2023.0111

The Australian Traumatic Brain Injury Initiative: systematic review of clinical factors associated with outcomes in people with moderate-severe traumatic brain injury

2024

Journal Article

Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis

Ceric, Ameldina, Holgersson, Johan, May, Teresa L., Skrifvars, Markus B., Haestbacka, Johanna, Saxena, Manoj, Aneman, Anders, Delaney, Anthony, Reade, Michael C., Delcourt, Candice, Jakobsen, Janus Christian and Nielsen, Niklas (2024). Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis. Eclinicalmedicine, 71 102569, 1-12. doi: 10.1016/j.eclinm.2024.102569

Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis

2024

Journal Article

Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial

Aitken, Leanne M., Emerson, Lydia M., Kydonaki, Kalliopi, Blackwood, Bronagh, Creagh-Brown, Benedict, Lone, Nazir I., McKenzie, Cathrine A., Reade, Michael C., Weir, Christopher J., Wise, Matt P. and Walsh, Timothy S. (2024). Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial. BMJ Open, 14 (4) e081637, 1-7. doi: 10.1136/bmjopen-2023-081637

Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial

2024

Journal Article

The Australian Traumatic Brain Injury Initiative: Review and Recommendations for Outcome Measures for Use With Adults and Children After Moderate-to-Severe Traumatic Brain Injury

Ponsford, Jennie L., Hicks, Amelia J., Bagg, Matthew K., Phyland, Ruby, Carrier, Sarah, James, Amelia C., Lannin, Natasha A., Rushworth, Nick, O’Brien, Terence J., Cameron, Peter A., Cooper, D. Jamie, Hill, Regina, Gabbe, Belinda J., Fitzgerald, Melinda, Alexander, Tara, Anderson, Vicki, Antonic-Baker, Ana, Armstrong, Elizabeth, Babl, Franz E., Balogh, Zsolt J., Barlow, Karen M., Bellapart, Judith, Bidargaddi, Niranjan, Bosio, Erika, Bragge, Peter, Bynevelt, Michael, Caeyenberghs, Karen, Capell, Jacquelin, Chai, Kevin E.K. ... AUS-TBI Initiative Investigators (2024). The Australian Traumatic Brain Injury Initiative: Review and Recommendations for Outcome Measures for Use With Adults and Children After Moderate-to-Severe Traumatic Brain Injury. Neurotrauma Reports, 5 (1), 387-408. doi: 10.1089/neur.2023.0127

The Australian Traumatic Brain Injury Initiative: Review and Recommendations for Outcome Measures for Use With Adults and Children After Moderate-to-Severe Traumatic Brain Injury

2024

Journal Article

Patient blood management guideline for adults with critical bleeding

Mitra, Biswadev, Jorgensen, Margaret, Reade, Michael C., Keegan, Anastazia, Holley, Anthony, Farmer, Shannon, Harvey, Nichole, Winearls, James, Parr, Michael, French, Craig J. and for the Clinical and Consumer Reference Group for the Update of Patient Blood Management Guidelines (Module 1: Critical Bleeding/Massive Transfusion) (2024). Patient blood management guideline for adults with critical bleeding. Medical Journal of Australia, 220 (4), 211-216. doi: 10.5694/mja2.52212

Patient blood management guideline for adults with critical bleeding

2024

Journal Article

Transforming research to improve therapies for trauma in the twenty-first century

Juffermans, Nicole P., Gozden, Tarik, Brohi, Karim, Davenport, Ross, Acker, Jason P., Reade, Michael C., Maegele, Marc, Neal, Matthew D. and Spinella, Philip C. (2024). Transforming research to improve therapies for trauma in the twenty-first century. Critical Care, 28 (1) 45. doi: 10.1186/s13054-024-04805-6

Transforming research to improve therapies for trauma in the twenty-first century

2024

Journal Article

PRECISION-TBI: a study protocol for a vanguard prospective cohort study to enhance understanding and management of moderate to severe traumatic brain injury in Australia

Jeffcote, Toby, Battistuzzo, Camila R, Plummer, Mark P, McNamara, Robert, Anstey, James, Bellapart, Judith, Roach, Rebecca, Chow, Andrew, Westerlund, Torgeir, Delaney, Anthony, Bihari, Shailesh, Bowen, David, Weeden, Mark, Trapani, Anthony, Reade, Michael, Jeffree, Rosalind L, Fitzgerald, Melinda, Gabbe, Belinda J, O'Brien, Terence J, Nichol, Alistair D, Cooper, D James, Bellomo, Rinaldo and Udy, Andrew (2024). PRECISION-TBI: a study protocol for a vanguard prospective cohort study to enhance understanding and management of moderate to severe traumatic brain injury in Australia. BMJ Open, 14 (2) e080614, 1-7. doi: 10.1136/bmjopen-2023-080614

PRECISION-TBI: a study protocol for a vanguard prospective cohort study to enhance understanding and management of moderate to severe traumatic brain injury in Australia

2024

Journal Article

The Australian traumatic brain injury initiative: systematic review and consensus process to determine the predictive value of pre-existing health conditions for people with moderate-severe traumatic brain injury

Antonic-Baker, Ana, Auvrez, Clarissa, Tao, Gerard, Bagg, Matthew K., Gadowski, Adelle, McKimmie, Ancelin, Hicks, Amelia J., Hill, Regina, Romero, Lorena, Ponsford, Jennie L., Lannin, Natasha A., Gabbe, Belinda J., Cameron, Peter A., Cooper, D. Jamie, Rushworth, Nick, Fitzgerald, Melinda, O'Brien, Terence J., Alexander, Tara, Anderson, Vicki, Armstrong, Elizabeth, Babl, Franz E., Balogh, Zsolt J., Barlow, Karen M. (AUS-TBI Initiative Investigators group member), Bellapart, Judith, Bidargaddi, Niranjan, Bosio, Erika, Bragge, Peter, Bynevelt, Michael, Caeyenberghs, Karen ... Zeeman, Heidi (2024). The Australian traumatic brain injury initiative: systematic review and consensus process to determine the predictive value of pre-existing health conditions for people with moderate-severe traumatic brain injury. Journal of Neurotrauma. doi: 10.1089/neu.2023.0462

The Australian traumatic brain injury initiative: systematic review and consensus process to determine the predictive value of pre-existing health conditions for people with moderate-severe traumatic brain injury

2023

Journal Article

Comment: Is off-label medication use in the ICU a problem?

Cotta, Menino O., Roberts, Jason A. and Reade, Michael C. (2023). Comment: Is off-label medication use in the ICU a problem?. Critical Care, 27 (1) 288, 288. doi: 10.1186/s13054-023-04546-y

Comment: Is off-label medication use in the ICU a problem?

2023

Journal Article

Transfusion practices in intensive care units: an Australian and New Zealand point prevalence study

Flint, Andrew W. J., Brady, Karina, Wood, Erica M., Thao, Le Thi Phuong, Hammond, Naomi, Knowles, Serena, Nangla, Conrad, Reade, Michael C. and McQuilten, Zoe K. (2023). Transfusion practices in intensive care units: an Australian and New Zealand point prevalence study. Critical Care and Resuscitation, 25 (4), 193-200. doi: 10.1016/j.ccrj.2023.10.006

Transfusion practices in intensive care units: an Australian and New Zealand point prevalence study

2023

Journal Article

The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management

Tsigaras, Zac A., Weeden, Mark, McNamara, Robert, Jeffcote, Toby, Udy, Andrew A., Anstey, James, Plummer, Mark, Bellapart, Judith, Chow, Andrew, Delaney, Anthony, Bihari, Shailesh, Bowen, David, Reade, Michael, Jeffree, Lindy, Fitzgerald, Melinda, O'Brien, Terry, Nichol, Alistair, Bellomo, Rinaldo, Cooper, Jamie, Trapani, Tony and Battistuzzo, Camila (2023). The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management. Critical Care and Resuscitation, 25 (4), 229-236. doi: 10.1016/j.ccrj.2023.10.009

The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management