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Dr John-Paul Tung
Dr

John-Paul Tung

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Overview

Background

John-Paul Tung is a Senior Research Fellow at Australian Red Cross Lifeblood (Lifeblood). He leads a program of research focused on the changes that occur in blood in between collection and transfusion, as well as how these changes might impact transfused patients. Particular focuses are on transfusion-related acute lung inujry (TRALI), transfusion-associated circulatory overload (TACO), and extracellular vesicles. He leads a research team of five Senior Research Assistants and three Research Assistants. He also supervises several PhD and Masters students. He holds an Honorary Senior Research Fellow position with the Faculty of Medicine at UQ. He also holds an adjunct Associate Professor position with the University of the Sunshine Coast and an adjunct Senior Lecturer position with QUT. He is also a former Secretary and Council Member of the International Society of Blood Transfusion's Young Professionals Council.

John-Paul completed a Bachelor of Science at UQ in 1999, after which he worked as a Scientist in nucleic acid testing in Brisbane, Melbourne and London. After returning to Brisbane, he commenced work as a Research Scientist with Lifeblood (formerly the Blood Service) in 2007. John-Paul then commenced a PhD with UQ and Prince Charles Hospital's Critical Care Research Group in 2008. His PhD, conferred in 2012, invovled the development of the first large animal model of TRALI using sheep, and resulted in several awards including best paper prizes from the International Society of Blood Transfusion and the Prince Charles Hospital as well as other awards from the Australian and New Zealand Society of Blood Transfusion and the British Blood Transfusion Society.

Availability

Dr John-Paul Tung is:
Available for supervision

Research impacts

As well as internal Lifeblood research project funding, John-Paul has been an investigator on over 20 competitive external grants worth over $7.5 million, including from the NHMRC, the ARC, and the Emergency Medicine Foundation. John-Paul has published over 40 papers including in American Journal of Respiratory and Critical Care Medicine (JIF 30.5), Intensive Care Medicine (JIF 17.4), Critical Care (JIF 9.1), and Blood Reviews (JIF 8.3). He has presented at international and national conferences, inculding invited presenations at the International Society of Blood Transfusion Congress, the Royal College of Pathologists Association Pathology Update, and the Brazilian Congress of Hematology, Hemotherapy, and Cellular Therapy. He has supervised over 20 research students including three PhD completions, two Masters completions, and eight Honours completions. He has several on-going academic and clincal collaborations including with the the Royal Brisbane and Women's Hospital, the Prince Charles Hospital, the Australian Defence Force, and the Baker Institute.

Works

Search Professor John-Paul Tung’s works on UQ eSpace

67 works between 2008 and 2024

1 - 20 of 67 works

2024

Journal Article

Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

Obonyo, Nchafatso. G., Dhanapathy, Vikash, White, Nicole, Sela, Declan P., Rachakonda, Reema H., Tunbridge, Matthew, Sim, Beatrice, Teo, Derek, Nadeem, Zohaib, See Hoe, Louise E., Bassi, Gianluigi Li, Fanning, Jonathon P., Tung, John-Paul, Suen, Jacky Y. and Fraser, John F. (2024). Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study. Journal of Cardiothoracic Surgery, 19 (1) 475. doi: 10.1186/s13019-024-02974-7

Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

2024

Journal Article

Characterization of novel Rh variant (CETW) associated with haemolytic disease of fetus and newborn using recombinant technology

Zhao, Shen, Radenkovic, Filip, Flower, Robert, Zacchi, Lucia, Jones, Martina, Wilson, Brett, Liew, Yew Wah, Tung, John-Paul and Hyland, Catherine (2024). Characterization of novel Rh variant (CETW) associated with haemolytic disease of fetus and newborn using recombinant technology. Pathology, 56 (Supplement 1), S100-S100. doi: 10.1016/j.pathol.2023.12.336

Characterization of novel Rh variant (CETW) associated with haemolytic disease of fetus and newborn using recombinant technology

2024

Journal Article

Extracellular vesicles in fresh frozen plasma and cryoprecipitate: Impact on in vitro endothelial cell viability

Hwang, Ji Hui, Tung, John-Paul, Harkin, Damien G., Flower, Robert L. and Pecheniuk, Natalie M. (2024). Extracellular vesicles in fresh frozen plasma and cryoprecipitate: Impact on in vitro endothelial cell viability. Transfusion. doi: 10.1111/trf.17959

Extracellular vesicles in fresh frozen plasma and cryoprecipitate: Impact on in vitro endothelial cell viability

2023

Journal Article

Intraoperative cell salvage: The impact on immune cell numbers

Roets, Michelle, Sturgess, David, Tran, Thu, Obeysekera, Maheshi, Perros, Alexis, Tung, John-Paul, Flower, Robert, van Zundert, Andre and Dean, Melinda (2023). Intraoperative cell salvage: The impact on immune cell numbers. PLoS One, 18 (8) e0289177, 1-19. doi: 10.1371/journal.pone.0289177

Intraoperative cell salvage: The impact on immune cell numbers

2023

Journal Article

Investigation of the effect of pre‐analytical factors on particle concentration and size in cryoprecipitate using nanoparticle tracking analysis

Hwang, Ji Hui, Tung, John‐Paul, Harkin, Damien G., Flower, Robert L. and Pecheniuk, Natalie M. (2023). Investigation of the effect of pre‐analytical factors on particle concentration and size in cryoprecipitate using nanoparticle tracking analysis. Transfusion Medicine, 33 (5), 398-402. doi: 10.1111/tme.12986

Investigation of the effect of pre‐analytical factors on particle concentration and size in cryoprecipitate using nanoparticle tracking analysis

2023

Journal Article

Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study

Obonyo, Nchafatso G., Lu, Lawrence Y., White, Nicole M., Sela, Declan P., Rachakonda, Reema H., Teo, Derek, Tunbridge, Matthew, Sim, Beatrice, See Hoe, Louise E., Fanning, Jonathon P., Tung, John‐Paul, McKnoulty, Matthew, Bassi, Gianluigi Li, Suen, Jacky Y. and Fraser, John F. (2023). Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study. International Journal of Gynecology and Obstetrics, 164 (1), 184-191. doi: 10.1002/ijgo.14997

Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study

2023

Conference Publication

Effects of Red Blood Cell Transfusion on Patients Undergoing Cardiac Surgery in Queensland—A Retrospective Cohort Study

Dhanapathy, V., Obonyo, N., White, N., Sela, D., Rachakonda, R., Tunbridge, M., Sim, B., Teo, D., Hoe, L. See, Fanning, J., Tung, J., Suen, J. and Fraser, J. (2023). Effects of Red Blood Cell Transfusion on Patients Undergoing Cardiac Surgery in Queensland—A Retrospective Cohort Study. 71st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Adelaide, SA Australia, 3-6 August 2023. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2023.06.458

Effects of Red Blood Cell Transfusion on Patients Undergoing Cardiac Surgery in Queensland—A Retrospective Cohort Study

2023

Conference Publication

Proposal of a reliable scoring system for the histological assessment of multiorgan injury in large animal models of ischaemia and shock

Palmieri, C., See Hoe, L., Dyer, W., Heinsar, S., Rozencwaig, S., Tung, J.P., Bartnikowski, N., Passmore, M., Bouquet, M., Hislop, K., Wilson, E., Li Bassi, g., Mcgiffin, D., Suen, J. and Fraser, J. (2023). Proposal of a reliable scoring system for the histological assessment of multiorgan injury in large animal models of ischaemia and shock. 2022 Annual Congress of the European Society of Veterinary Pathology and European College of Veterinary Pathologists, Athens, Greece, 7 - 10 September 2022. London, United Kingdom: Elsevier. doi: 10.1016/j.jcpa.2023.03.059

Proposal of a reliable scoring system for the histological assessment of multiorgan injury in large animal models of ischaemia and shock

2023

Journal Article

Next generation sequencing to identify iron status and individualise blood donors' experience

Jacko, Georgina, Sivakaanthan, Aarany, Obeysekera, Maheshi, Welvaert, Marijke, Viennet, Elvina, Hyland, Catherine, Tung, John-Paul, Perros, Alexis J, Flower, Robert L and Roulis, Eileen (2023). Next generation sequencing to identify iron status and individualise blood donors' experience. Blood transfusion = Trasfusione del sangue, 21 (6), 463-471. doi: 10.2450/BloodTransfus.499

Next generation sequencing to identify iron status and individualise blood donors' experience

2023

Journal Article

The impact of revised definitions for transfusion‐associated circulatory overload and transfusion‐related acute lung injury on haemovigilance reporting

Yuan, Yin, Dennington, Peta M., Daly, James, Baidya, Shoma and Tung, John‐Paul (2023). The impact of revised definitions for transfusion‐associated circulatory overload and transfusion‐related acute lung injury on haemovigilance reporting. Vox Sanguinis, 118 (3), 199-206. doi: 10.1111/vox.13402

The impact of revised definitions for transfusion‐associated circulatory overload and transfusion‐related acute lung injury on haemovigilance reporting

2023

Conference Publication

Molecular typing to personalise donor donation frequency

Flower, Robert L., Perros, Alexis J., Jacko, Georgina, Welvaert, Marijke, Viennet, Elvina, Hyland, Catherine, Tung, John-Paul and Roulis, Eileen (2023). Molecular typing to personalise donor donation frequency. Pathology Update 2023, Melbourne, VIC Australia, 24-26 February 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.pathol.2022.12.304

Molecular typing to personalise donor donation frequency

2023

Conference Publication

Donor variability affects the outcome for the monocyte monolayer assay (MMA)

Tran, Thu V., Powley, Tanya, Tung, John-Paul, Flower, Robert L. and Dean, Melinda M. (2023). Donor variability affects the outcome for the monocyte monolayer assay (MMA). Pathology Update 2023, Melbourne, VIC Australia, 24-26 February 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2022.12.329

Donor variability affects the outcome for the monocyte monolayer assay (MMA)

2023

Journal Article

Limited potential of sheep as a large animal to model transfusion-related acute lung injury mediated by antibodies against human neutrophil antigen 3a

Radenkovic, Filip, Burton, Mark, Hassell, Penny, Chiaretti, Sara, Bui, Xuan, Zhao, Shen, Jones, Martina, Flower, Robert and Tung, John-Paul (2023). Limited potential of sheep as a large animal to model transfusion-related acute lung injury mediated by antibodies against human neutrophil antigen 3a. Annals of Blood. doi: 10.21037/aob-23-57

Limited potential of sheep as a large animal to model transfusion-related acute lung injury mediated by antibodies against human neutrophil antigen 3a

2022

Journal Article

Transfusion-related acute lung injury (TRALI): a retrospective review of reported cases in Queensland, Australia over 20 years

Sivakaanthan, Aarany, Swain, Fiona, Pahn, Gail, Goodison, Kathryn, Gutta, Naadir, Holdsworth, Rhonda, Baidya, Shoma and Tung, John-Paul (2022). Transfusion-related acute lung injury (TRALI): a retrospective review of reported cases in Queensland, Australia over 20 years. Blood transfusion, 20 (6), 454-464. doi: 10.2450/2022.0020-22

Transfusion-related acute lung injury (TRALI): a retrospective review of reported cases in Queensland, Australia over 20 years

2022

Journal Article

Human neutrophil antigen 3 genotype impacts neutrophil-mediated endothelial cell cytotoxicity in a two-event model of TRALI

Chiaretti, Sara, Burton, Mark, Hassel, Penny, Radenkovic, Filip, Devikashri, Nilam, Sultana, Annette J, Temple, Fergal T, Dean, Melinda M and Tung, John-Paul (2022). Human neutrophil antigen 3 genotype impacts neutrophil-mediated endothelial cell cytotoxicity in a two-event model of TRALI. Blood transfusion, 20 (6), 465-474. doi: 10.2450/2022.0013-22

Human neutrophil antigen 3 genotype impacts neutrophil-mediated endothelial cell cytotoxicity in a two-event model of TRALI

2022

Journal Article

Psychological impact of the COVID-19 pandemic on young professionals in blood banks and transfusion services: A global cross-sectional survey

Al-Riyami, Arwa Z., Masser, Barbara, Herczenik, Eszter, Arora, Satyam, Boateng, Lilian Antwi, Dinardo, Carla Luana, Hutchinson, Tyler, Ji, Yanli, Langi Sasongko, Syeldy, Tung, John-Paul and Panchatcharam, Sathiya Murthi (2022). Psychological impact of the COVID-19 pandemic on young professionals in blood banks and transfusion services: A global cross-sectional survey. Vox Sanguinis, 117 (5), 685-692. doi: 10.1111/vox.13236

Psychological impact of the COVID-19 pandemic on young professionals in blood banks and transfusion services: A global cross-sectional survey

2022

Journal Article

Transfusion-related acute lung injury (TRALI): potential pathways of development, strategies for prevention and treatment, and future research directions

Tung, John-Paul, Chiaretti, Sara, Dean, Melinda M., Sultana, Annette J., Reade, Michael C. and Fung, Yoke Lin (2022). Transfusion-related acute lung injury (TRALI): potential pathways of development, strategies for prevention and treatment, and future research directions. Blood Reviews, 53 100926, 100926. doi: 10.1016/j.blre.2021.100926

Transfusion-related acute lung injury (TRALI): potential pathways of development, strategies for prevention and treatment, and future research directions

2022

Journal Article

Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock

Dyer, Wayne B., Simonova, Gabriela, Chiaretti, Sara, Bouquet, Mahe, Wellburn, Rebecca, Heinsar, Silver, Ainola, Carmen, Wildi, Karin, Sato, Kei, Livingstone, Samantha, Suen, Jacky Y., Irving, David O., Tung, John-Paul, li Bassi, Gianluigi and Fraser, John F. (2022). Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock. Intensive Care Medicine Experimental, 10 (1) 12, 12. doi: 10.1186/s40635-022-00439-6

Recovery of organ-specific tissue oxygen delivery at restrictive transfusion thresholds after fluid treatment in ovine haemorrhagic shock

2021

Journal Article

A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death

See Hoe, Louise E., Wildi, Karin, Obonyo, Nchafatso G., Bartnikowski, Nicole, McDonald, Charles, Sato, Kei, Heinsar, Silver, Engkilde-Pedersen, Sanne, Diab, Sara, Passmore, Margaret R., Wells, Matthew A., Boon, Ai-Ching, Esguerra, Arlanna, Platts, David G., James, Lynnette, Bouquet, Mahe, Hyslop, Kieran, Shuker, Tristan, Ainola, Carmen, Colombo, Sebastiano M., Wilson, Emily S., Millar, Jonathan E., Malfertheiner, Maximillian V., Reid, Janice D., O’Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Sato, Noriko, He, Ting ... Fraser, John F. (2021). A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death. Intensive Care Medicine Experimental, 9 (1) 60, 1-24. doi: 10.1186/s40635-021-00425-4

A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death

2021

Journal Article

An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management

Dyer, Wayne B., Tung, John-Paul, Li Bassi, Gianluigi, Wildi, Karin, Jung, Jae-Seung, Colombo, Sebastiano Maria, Rozencwajg, Sacha, Simonova, Gabriela, Chiaretti, Sara, Temple, Fergal T., Ainola, Carmen, Shuker, Tristan, Palmieri, Chiara, Shander, Aryeh, Suen, Jacky Y., Irving, David O. and Fraser, John F. (2021). An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management. Shock, 56 (6), 1080-1091. doi: 10.1097/SHK.0000000000001805

An ovine model of haemorrhagic shock and resuscitation, to assess recovery of tissue oxygen delivery and oxygen debt, and inform patient blood management

Funding

Past funding

  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant

Supervision

Availability

Dr John-Paul Tung is:
Available for supervision

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Media

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