
Overview
Background
Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.
The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.
Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia
Availability
- Professor Bryan Mowry is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists
Works
Search Professor Bryan Mowry’s works on UQ eSpace
2015
Journal Article
Paracingulate sulcus morphology is associated with hallucinations in the human brain
Garrison, Jane R., Fernyhough, Charles, McCarthy-Jones, Simon, Haggard, Mark, The Australian Schizophrenia Research Bank, Carr, Vaughan, Schall, Ulrich, Scott, Rodney, Jablensky, Assen, Mowry, Bryan, Michie, Patricia, Catts, Stanley, Henskens, Frans, Pantelis, Christos, Loughland, Carmel and Simons, Jon S. (2015). Paracingulate sulcus morphology is associated with hallucinations in the human brain. Nature Communications, 6 (1) 8956, 8956.1-8956.6. doi: 10.1038/ncomms9956
2015
Journal Article
Executive functioning in schizophrenia: Unique and shared variance with measures of fluid intelligence
Martin A.K, Mowry, B, Reutens, D and Robinson, G.A (2015). Executive functioning in schizophrenia: Unique and shared variance with measures of fluid intelligence. Brain and Cognition, 99, 57-67. doi: 10.1016/j.bandc.2015.07.009
2015
Journal Article
Common genetic risk variants are associated with positive symptoms and decision-making ability in patients with schizophrenia
Martin, Andrew K, Robinson, G, Reutens, D and Mowry, B (2015). Common genetic risk variants are associated with positive symptoms and decision-making ability in patients with schizophrenia. Psychiatry Research, 229 (1-2), 606-608. doi: 10.1016/j.psychres.2015.04.045
2015
Journal Article
Clinical and parental age characteristics of rare copy number variant burden in patients with schizophrenia
Martin, Andrew K., Robinson, Gail, Reutens, David and Mowry, Bryan (2015). Clinical and parental age characteristics of rare copy number variant burden in patients with schizophrenia. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 168 (5), 374-382. doi: 10.1002/ajmg.b.32321
2015
Journal Article
Interest in employment among people with schizophrenia
Westcot, Cassandra, Waghorn, Geoffrey, McLean, Duncan, Statham, Dixie and Mowry, Bryan (2015). Interest in employment among people with schizophrenia. American Journal of Psychiatric Rehabilitation, 18 (2), 187-207. doi: 10.1080/15487768.2014.954162
2015
Journal Article
Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants
Duan, Jubao, Sanders, Alan R., Moy, Winton, Drigalenko, Eugene I., Brown, Eric C., Freda, Jessica, Leites, Catherine, Goering, Harald H. H., Gejman, Pablo V., Molecular Genetics of Schizophrenia Consortium and Mowry, Bryan (2015). Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants. Human Molecular Genetics, 24 (16), 4674-4685. doi: 10.1093/hmg/ddv199
2015
Journal Article
Role functioning among adults with schizophrenia
Westcott, Cassandra, Waghorn, Geoff, McLean, Duncan, Statham, Dixie and Mowry, Bryan (2015). Role functioning among adults with schizophrenia. British Journal of Occupational Therapy, 78 (3), 158-165. doi: 10.1177/0308022615573372
2015
Conference Publication
Characterizing large, rare copy number deletions in schizophrenia: a clinical, cognitive, and neuroimaging study
Martin, Andrew K., Robinson, Gail, Reutens, David and Mowry, Bryan (2015). Characterizing large, rare copy number deletions in schizophrenia: a clinical, cognitive, and neuroimaging study. 15th International Congress on Schizophrenia Research (ICOSR), Colorado Springs, CO USA, 28 March-1 April 2015. Oxford, United Kingdom: Oxford University Press.
2015
Journal Article
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
Bulik-Sullivan, Brendan K., Loh, Po-Ru, Finucane, Hilary K., Ripke, Stephen, Yang, Jian, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson, Nick, Daly, Mark J., Price, Alkes L., Neale, Benjamin M., Nertney, Deborah A., Mowry, Bryan J. and Catts, Stanley V. (2015). LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics, 47 (3), 291-295. doi: 10.1038/ng.3211
2015
Journal Article
Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies
Arnedo, Javier, Svrakic, Dragan M., del Val, Coral, Romero-Zaliz, Rocio, Hernandez-Cuervo, Helena, Fanous, Ayman H., Pato, Michele T., Pato, Carlos N., de Erausquin, Gabriel A., Cloninger, C. Robert, Zwir, Igor, Molecular Genetics of Schizophrenia Consortium and Mowry, B. J. (2015). Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies. American Journal of Psychiatry, 172 (2), 139-153. doi: 10.1176/appi.ajp.2014.14040435
2015
Journal Article
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
O'Dushlaine, Colm, Rossin, Lizzy, Lee, Phil H., Duncan, Laramie, Parikshak, Neelroop N., Newhouse, Stephen, Ripke, Stephan, Neale, Benjamin M., Purcell, Shaun M., Posthuma, Danielle, Nurnberger, John I., Lee, S. Hong, Faraone, Stephen V., Perlis, Roy H., Mowry, Bryan J, Thapar, Anita, Goddard, Michael E., Witte, John S., Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A., Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E., Asherson, Philip, Azevedo, Maria H. ... Breen, Gerome (2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience, 18 (2), 199-209. doi: 10.1038/nn.3922
2015
Conference Publication
Voxel-Based Morphometry of Patients with Schizophrenia and Schizoaffective Disorders
Shaffer, J., Choupan, J., Mowry, B., Yang, Z. and Reutens, D. (2015). Voxel-Based Morphometry of Patients with Schizophrenia and Schizoaffective Disorders. Southern Regional Meeting of the American-Federation-for-Medical-Research, New Orleans, LA, United States, 26-28 February 2015. Philadelphia, United States: Lippincott Williams & Wilkins. doi: 10.1097/JIM.0000000000000146
2015
Journal Article
Genome-wide association study suggested the PTPRD polymorphisms were associated with weight gain effects of atypical antipsychotic medications
Yu, Hao, Wang, Lifang, Lv, Luxian, Ma, Cuicui, Du, Bo, Lu, Tianlan, Jin, Chao, Yan, Hao, Yang, Yongfeng, Li, Wenqiang, Ruan, Yanyan, Zhang, Hongyan, Zhang, Hongxing, Mi, Weifeng, Mowry, Bryan, Ma, Wenbin, Li, Keqing, Zhang, Dai and Yue, Weihua (2015). Genome-wide association study suggested the PTPRD polymorphisms were associated with weight gain effects of atypical antipsychotic medications. Schizophrenia Bulletin, 42 (3), 814-823. doi: 10.1093/schbul/sbv179
2015
Journal Article
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Lee, S. Hong, Byrne, Enda M., Hultman, Christina M., Kahler, Anna, Vinkhuyzen, Anna A. E., Ripke, Stephan, Andreassen, Ole A., Frisell, Thomas, Gusev, Alexander, Hu, Xinli, Karlsson, Robert, Mantzioris, Vasilis X., McGrath, John J., Mehta, Divya, Stahl, Eli A., Zhao, Qiongyi, Kendler, Kenneth S., Sullivan, Patrick F., Price, Alkes L., O'Donovan, Michael, Okada, Yukinori, Mowry, Bryan J., Raychaudhuri, Soumya, Wray, Naomi R., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Rheumatoid Arthritis Consortium International and Visscher, Peter M . (2015). New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology, 44 (5) dyv136, 1-16. doi: 10.1093/ije/dyv136
2014
Journal Article
Cognitive and structural neuroimaging characteristics of schizophrenia patients with large, rare copy number deletions
Martin, Andrew Kenneth, Robinson, Gail, Reutens, David and Mowry, Bryan (2014). Cognitive and structural neuroimaging characteristics of schizophrenia patients with large, rare copy number deletions. Psychiatry Research: Neuroimaging, 224 (3), 311-318. doi: 10.1016/j.pscychresns.2014.10.006
2014
Journal Article
A rare functional noncoding variant at the GWAS-Implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder
Duan, Jubao, Shi, Jianxin, Fiorentino, Alessia, Leites, Catherine, Chen, Xiangning, Moy, Winton, Chen, Jingchun, Alexandrov, Boian S., Usheva, Anny, He, Deli, Freda, Jessica, O'Brien, Niamh L., MGS, GPC, McQuillin, Andrew, Sanders, Alan R., Gershon, Elliot S., DeLisi, Lynn E., Bishop, Alan R., Gurling, Hugh M. D., Pato, Michele T., Levinson, Douglas F., Kendler, Kenneth S., Pato, Carlos N., Gejman, Pablo V. and Mowry, Bryan J. (2014). A rare functional noncoding variant at the GWAS-Implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. American Journal of Human Genetics, 95 (6), 744-753. doi: 10.1016/j.ajhg.2014.11.001
2014
Journal Article
Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
Gusev, Alexander, Lee, S. Hong, Trynka, Gosia, Finucane, Hilary, Vilhjálmsson, Bjarni J., Xu, Han, Zang, Chongzhi, Ripke, Stephan, Bulik-Sullivan, Brendan, Stahl, Eli, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kaehler, Anna K., Hultman, Christina M., Purcell, Shaun M., McCarroll, Steven A., Daly, Mark, Pasaniuc, Bogdan, Sullivan, Patrick F., Neale, Benjamin M., Wray, Naomi R., Raychaudhuri, Soumya, Price, Alkes L., Visscher, Peter M., Mowry, Bryan J., Psychosis Endophenotypes International Consortium and Wellcome Trust Case Control Consortium (2014). Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases. American Journal of Human Genetics, 95 (5), 535-552. doi: 10.1016/j.ajhg.2014.10.004
2014
Journal Article
Copy number deletion burden is associated with cognitive, structural, and resting-state network differences in patients with schizophrenia
Martin, A. K., Robinson, G., Reutens, D. and Mowry, B. (2014). Copy number deletion burden is associated with cognitive, structural, and resting-state network differences in patients with schizophrenia. Behavioural Brain Research, 272, 324-334. doi: 10.1016/j.bbr.2014.07.002
2014
Journal Article
DSM-IV "Criterion A" schizophrenia symptoms across ethnically different populations: evidence for differing psychotic symptom content or structural organization?
McLean, Duncan, Thara, Rangaswamy, John, Sujit, Barrett, Robert, Loa, Peter, McGrath, John and Mowry, Bryan (2014). DSM-IV "Criterion A" schizophrenia symptoms across ethnically different populations: evidence for differing psychotic symptom content or structural organization?. Culture, Medicine, and Psychiatry, 38 (3), 408-426. doi: 10.1007/s11013-014-9385-8
2014
Journal Article
Cannabis abuse and age at onset in schizophrenia patients with large, rare copy number variants
Martin, Andrew Kenneth, Robinson, Gail, Reutens, David and Mowry, Bryan (2014). Cannabis abuse and age at onset in schizophrenia patients with large, rare copy number variants. Schizophrenia Research, 155 (1-3), 21-25. doi: 10.1016/j.schres.2014.03.004
Funding
Past funding
Supervision
Availability
- Professor Bryan Mowry is:
- Available for supervision
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Supervision history
Completed supervision
-
2021
Doctor Philosophy
New technologies and models to investigate the functional role of neurexins in zebrafish
Principal Advisor
Other advisors: Dr Jean Giacomotto
-
2017
Doctor Philosophy
The Neuroimaging and Genetics of Emotion Perception in Schizophrenia
Principal Advisor
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2016
Doctor Philosophy
Contrasting the Expression of Psychotic Disorders in Ethnically Different Populations
Principal Advisor
Other advisors: Professor John McGrath
-
2015
Doctor Philosophy
Characterizing copy number variants in schizophrenia: a clinical, neuropsychological, and neuroimaging study.
Principal Advisor
Other advisors: Professor Gail Robinson
-
2015
Doctor Philosophy
Analysis of non-coding RNA expression in schizophrenia brain
Principal Advisor
Other advisors: Honorary Professor Jake Gratten
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2002
Doctor Philosophy
MOLECULAR CANDIDATES FOR SCHIZOPHRENIA
Principal Advisor
Other advisors: Professor John McGrath
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2012
Doctor Philosophy
Immune dysregulation in schizophrenia: Do some cases of schizophrenia have an autoimmune basis?
Associate Advisor
Other advisors: Emeritus Professor Michael Pender, Associate Professor Judith Greer
Media
Enquiries
Contact Professor Bryan Mowry directly for media enquiries about:
- Culture and psychiatry
- Ethics - psychiatry
- Genetics and mental illnesses
- Health - mental
- Mental illness and genetics
- Psychiatric ethics
- Psychiatry - trans-cultural
- Schizophrenia
- Trans-cultural psychiatry
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