Professor Bryan Mowry
Professor

Bryan Mowry

Email: 

Background

Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.

The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.

Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia

Availability

Professor Bryan Mowry is:
Available for supervision
Media expert

Fields of research

Clinical sciences Genetics Neurosciences

Qualifications

  • Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists

Search Professor Bryan Mowry’s works on UQ eSpace

278 works between 1985 and 2024
All (278) Journal Article (215) Book Chapter (4) Conference Publication (58) Other Outputs (1)

61 - 80 of 278 works

2017

Journal Article

Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis

Sanders, A. R., Drigalenko, E. I., Duan, J., Moy, W., Freda, J., Göring, H. H.H., Gejman, P. V., Levinson, D. F., Shi, J., Buccola, N. G., Mowry, B. J., Freedman, R., Olincy, A., Amin, F., Black, D. W., Silverman, J. M., Byerley, W. F., Cloninger, C. R. and Svrakic, D. M. (2017). Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis. Translational Psychiatry, 7 (4) e1093, e1093-e1093. doi: 10.1038/tp.2017.47

Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis

2017

Journal Article

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

McLaughlin, Russell L., Schijven, Dick, Van Rheenen, Wouter, Van Eijk, Kriste R., O'Brien, Margaret, Kahn, Rene S., Ophoff, Roel A., Goris, An, Bradley, Daniel G., Al-Chalabi, Ammar, Van Den Berg, Leonard H., Luykx, Jurjen J., Hardiman, Orla, Veldink, Jan H., Project MinE GWAS Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Catts, Stanley V., Gratten, Jacob, Lee, S. Hong, Wray, Naomi R., Visscher, Peter M. and Mowry, Bryan J. (2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications, 8 (1) 14774, 14774. doi: 10.1038/ncomms14774

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

2017

Journal Article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, Christian R., Howrigan, Daniel P., Merico, Daniele, Thiruvahindrapuram, Bhooma, Wu, Wenting, Greer, Douglas S., Antaki, Danny, Shetty, Aniket, Holmans, Peter A., Pinto, Dalila, Gujral, Madhusudan, Brandler, William M., Malhotra, Dheeraj, Wang, Zhouzhi, Fuentes Fajarado, Karin V., Maile, Michelle S., Ripke, Stephan, Agartz, Ingrid, Albus, Margot, Alexander, Madeline, Amin, Farooq, Atkins, Joshua, Bacanu, Silviu A., Belliveau, Richard A., Jr., Bergen, Sarah E., Bertalan, Marcelo, Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W. ... Sebat, Jonathan (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics, 49 (1), 27-35. doi: 10.1038/ng.3725

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

2017

Conference Publication

Evidence for genetic overlap between schizophrenia and maternal age at first birth

Mehta, Divya, Tropf, Felix, Gratten, Jacob, Bacanu, Silviu, Bakshi, Andrew, Mowry, Bryan, Kendler, Kenneth, Yang, Jian, Visscher, Peter, McGrath, John, Mills, Melinda, Wray, Naomi and Lee, Sang Hong (2017). Evidence for genetic overlap between schizophrenia and maternal age at first birth. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, ON, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2015.09.010

Evidence for genetic overlap between schizophrenia and maternal age at first birth

2017

Conference Publication

Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans

Vinkhuyzen, Anna, John, Sujit, Periyasamy, Sathish, Wray, Naomi, Thara, Rangaswamy and Mowry, Bryan (2017). Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier.

Genome-wide association study in an Indian population reveals genetic overlap for schizophrenia with Europeans

2017

Conference Publication

Genome-wide association study of schizophrenia in the Iban of Sarawak reveals genetic overlap with Han Chinese and, to a lesser extent, Europeans

Periyasamy, Sathish, Barrett, Robert, Yue, Weihua, Gratten, Jacob, Nertney, Deborah, McLean, Duncan, Smith, Heather, Filippich, Cheryl, Loa, Peter, Zhang, Dai, Yolken, Robert and Mowry, Bryan (2017). Genome-wide association study of schizophrenia in the Iban of Sarawak reveals genetic overlap with Han Chinese and, to a lesser extent, Europeans. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier .

Genome-wide association study of schizophrenia in the Iban of Sarawak reveals genetic overlap with Han Chinese and, to a lesser extent, Europeans

2016

Journal Article

Mentalizing in schizophrenia: A multivariate functional MRI study

Martin, Andrew K., Dzafic, Ilvana, Robinson, Gail A., Reutens, David and Mowry, Bryan (2016). Mentalizing in schizophrenia: A multivariate functional MRI study. Neuropsychologia, 93 (Pt A), 158-166. doi: 10.1016/j.neuropsychologia.2016.10.013

Mentalizing in schizophrenia: A multivariate functional MRI study

2016

Journal Article

No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study

Johnson, Emma C., Bjelland, Douglas W., Howrigan, Daniel P., Abdellaoui, Abdel, Breen, Gerome, Borglum, Anders, Cichon, Sven, Degenhardt, Franziska, Forstner, Andreas J., Frank, Josef, Genovese, Giulio, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffman, Per, Maier, Wolfgang, Mattheisen, Manuel, Morris, Derek, Mowry, Bryan, Muller-Mhysok, Betram, Neale, Benjamin, Nenadic, Igor, Nothen, Markus M., O'Dushlaine, Colm, Rietschel, Marcella, Ruderfer, Douglas M., Rujescu, Dan, Schulze, Thomas G., Simonson, Matthew A., Stahl, Eli ... Keller, Matthew C. (2016). No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study. PLoS Genetics, 12 (10) e1006343, e1006343. doi: 10.1371/journal.pgen.1006343

No reliable association between runs of homozygosity and schizophrenia in a well-powered replication study

2016

Journal Article

Increased rare duplication burden genomewide in patients with treatment-resistant schizophrenia

Martin, A. K. and Mowry, B. (2016). Increased rare duplication burden genomewide in patients with treatment-resistant schizophrenia. Psychological Medicine, 46 (3), 469-476. doi: 10.1017/S0033291715001701

Increased rare duplication burden genomewide in patients with treatment-resistant schizophrenia

2016

Journal Article

White matter disruptions in schizophrenia are spatially widespread and topologically converge on brain network hubs

Klauser, Paul, Baker, Simon T., Cropley, Vanessa L. , Bousman, Chad, Fornito, Alex, Cocchi, Luca, Fullerton, Janice M., Rasser, Paul, Schall, Ulrich, Henskens, Frans , Michie, Patricia T., Loughland, Carmel, Catts, Stanley V. , Mowry, Bryan, Weickert, Thomas W., Shannon Weickert, Cynthia, Carr, Vaughan, Lenroot, Rhoshel, Pantelis, Christos and Zalesky, Andrew (2016). White matter disruptions in schizophrenia are spatially widespread and topologically converge on brain network hubs. Schizophrenia Bulletin, 43 (2), 425-435. doi: 10.1093/schbul/sbw100

White matter disruptions in schizophrenia are spatially widespread and topologically converge on brain network hubs

2016

Journal Article

Verbal initiation, suppression, and strategy use and the relationship with clinical symptoms in schizophrenia

Martin, Andrew K., Gibson, Emily C., Mowry, Bryan and Robinson,Gail A. (2016). Verbal initiation, suppression, and strategy use and the relationship with clinical symptoms in schizophrenia. Journal of the International Neuropsychological Society, 22 (7), 735-743. doi: 10.1017/S1355617716000552

Verbal initiation, suppression, and strategy use and the relationship with clinical symptoms in schizophrenia

2016

Journal Article

Dynamic emotion perception and prior expectancy

Dzafic, Ilvana, Martin, Andrew K., Hocking, Julia, Mowry, Bryan and Burianová, Hana (2016). Dynamic emotion perception and prior expectancy. Neuropsychologia, 86, 131-140. doi: 10.1016/j.neuropsychologia.2016.04.025

Dynamic emotion perception and prior expectancy

2016

Journal Article

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish

Giacomotto, J., Carroll, A. P., Rinkwitz, S., Mowry, B., Cairns, M. J. and Becker, T. S. (2016). Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish. Translational Psychiatry, 6 (5) e818, 1-10. doi: 10.1038/tp.2016.88

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish

2016

Journal Article

Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulation

Ragan, Chikako, Patel, Kalpana, Edson, Janette, Zhang, Zong-Hong, Gratten, Jacob and Mowry, Bryan (2016). Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulation. Schizophrenia Research, 183, 82-87. doi: 10.1016/j.schres.2016.11.024

Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulation

2016

Journal Article

Evidence for genetic overlap between schizophrenia and age at first birth in women

Mehta, Divya, Tropf, Felix C., Gratten, Jacob, Bakshi, Andrew, Zhu, Zhihong, Bacanu, Silviu-Alin, Hemani, Gibran, Magnusson, Patrik K. E., Barban, Nicola, Esko, Tonu, Metspalu, Andres, Snieder, Harold, Mowry, Bryan J., Kendler, Kenneth S., Yang, Jian, Visscher, Peter M., McGrath, John J., Mills, Melinda C., Wray, Naomi R. and Lee, S. Hong (2016). Evidence for genetic overlap between schizophrenia and age at first birth in women. Jama Psychiatry, 73 (5), 497-505. doi: 10.1001/jamapsychiatry.2016.0129

Evidence for genetic overlap between schizophrenia and age at first birth in women

2016

Conference Publication

Schizophrenia and cognitive dysfunction associated with the estrogen receptor 1 genotype

Weickert, C. Shannon, Fullerton, J. M., Hu, S., Kyaw, M., Schofield, P. R., Carr, V. J., Laughlin, C., Schall, U., Scott, R. J., Jablensky, A. V., Mowry, B., Michie, P. T., Catts, S. V., Henskens, F. A., Pantellis, C. and Weickert, T. W. (2016). Schizophrenia and cognitive dysfunction associated with the estrogen receptor 1 genotype. Unknown, Unknown, Unknown. London, United Kingdom: Sage Publications.

Schizophrenia and cognitive dysfunction associated with the estrogen receptor 1 genotype

2016

Conference Publication

Voxel-based Morphometry of Patients with Schizophrenia and Schizoaffective Disorders

Shaffer, Johnathon, Choupan, Jeiran, Mowry, Bryan, Yang, Zhengyi and Reutens, David (2016). Voxel-based Morphometry of Patients with Schizophrenia and Schizoaffective Disorders. AAN 68th Annual Meeting, Vancouver, Canada, 15 - 21 April 2016. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.86.16_supplement.p6.201

Voxel-based Morphometry of Patients with Schizophrenia and Schizoaffective Disorders

2016

Journal Article

Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes

Edwards, Alexis C., Bigdeli, Tim B., Docherty, Anna R., Bacanu, Silviu, Lee, Donghyung, de Candia, Teresa R., Moscati, Arden, Thiselton, Dawn L., Maher, Brion S., Wormley, Brandon K., Walsh, Dermot, O'Neill, Francis A., Kendler, Kenneth S., Riley, Brien P., Fanous, Ayman H. and Mowry, Bryan J. (2016). Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes. Schizophrenia Bulletin, 42 (2), 279-287. doi: 10.1093/schbul/sbv119

Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes

2016

Journal Article

Schizophrenia risk from complex variation of complement component 4

Sekar, Aswin, Bialas, Allison R., de Rivera, Heather, Davis, Avery, Hammond, Timothy R., Kamitaki, Nolan, Tooley, Katherine, Presumey, Jessy, Baum, Matthew, Van Doren, Vanessa, Genovese, Giulio, Rose, Samuel A., Handsaker, Robert E., Daly, Mark J., Carroll, Michael C., Stevens, Beth, McCarroll, Steven A., Schizophrenia Working Group of the Psychiatric Genomics Consortium and Mowry, Bryan (2016). Schizophrenia risk from complex variation of complement component 4. Nature, 530 (7589), 177-183. doi: 10.1038/nature16549

Schizophrenia risk from complex variation of complement component 4

2015

Journal Article

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Loh, Po-Ru, Bhatia, Gaurav, Gusev, Alexander, Finucane, Hilary K., Bulik-Sullivan, Brendan K., Pollack, Samuela J., de Candia, Teresa R., Lee, Sang Hong, Wray, Naomi R., Kendler, Kenneth S., O'Donovan, Michael C., Neale, Benjamin M., Patterson, Nick, Price, Alkes L., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Visscher, Peter M. and Mowry, Bryan J. (2015). Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. Nature Genetics, 47 (12), 1385-1392. doi: 10.1038/ng.3431

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Past funding

  • 2022 - 2023
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish (NHMRC Project Grant administered by Griffith University)
    Griffith University
    Open grant
  • 2022
    Genotype Imputation Resources for Productive Genetic Disease Studies of Indigenous Oceanic Sub-Populations
    NHMRC IDEAS Grants
    Open grant
  • 2019 - 2022
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish.
    NHMRC Project Grant
    Open grant
  • 2016 - 2021
    Investigating the aetiopathogenic role of autoantibodies against the M1 muscarinic acetylcholine receptor in patients with first episode of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Using the Zebrafish to fight psychiatric disorders. From proof-of-principle to new insights and treatments
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2014 - 2016
    Dissecting the role of RYK in cortical neuron specification and schizophrenia
    NHMRC Project Grant
    Open grant
  • 2014 - 2018
    Genetic analysis of de novo and inherited exome variation in schizophrenia
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Statistical analyses of whole genome genotype data to better understand psychiatric disorders
    NHMRC Project Grant
    Open grant
  • 2012 - 2024
    Genetics of Schizophrenia Research Collaboration Programme
    West Moreton Hospital and Health Service
    Open grant
  • 2012
    Genetics of Schizophrenia Research Collaboration Programme
    Queensland Health
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2012
    Establishing a UWA-UQ network for collaboration in Autism Research
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2010
    High performance computing cluster to expand research capacity in neuroscience modelling, imaging and bioinformatics
    NHMRC Equipment Grant
    Open grant
  • 2010 - 2013
    Identifying eQTLs and endophenotyping known CNVs in a large Australian schizophrenia sample
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Linkage and association studies of schizophrenia in an isolated population
    NHMRC Project Grant
    Open grant
  • 2010
    Next-generation DNA sequencer to accelerate discovery in molecular and cellular research programs at QBI
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2014
    Studying the molecular basis of schizophrenia in a large, globally competitive Indian sample
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    QCMHR Operational (Genetics Laboratory Programme Funding)
    Queensland Health
    Open grant
  • 2006 - 2008
    Adiponectin - Multimerization, Secretion and Action
    NHMRC Project Grant
    Open grant
  • 2006
    Genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2003 - 2006
    Structural And Diffusion Tensor Neuroimaging In Twins Concordant And Discordant For Psychosis
    NHMRC Project Grant
    Open grant
  • 2002 - 2003
    Australian Psychotic Twins Study - MRI Research
    Schizophrenia Fellowship of South Qld Inc
    Open grant
  • 2000 - 2001
    A genetic study of schizophrenia in regional Tasmania: Initial genotyping of the first large pedigree
    Ramaciotti Foundation
    Open grant
  • 2000
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 1999 - 2003
    Molecular genetics of Schizophrenia
    United States National Institutes of Health
    Open grant
  • 1999 - 2001
    A Genetic Study of Schizophrenia in the Iban of Sarawak
    NHMRC Project Grant
    Open grant
  • 1999
    The molecular genetics of schizophrenia (2)
    Garvan Institute
    Open grant
  • 1998 - 2012
    QCMHR Operational (Genetics Research Project)
    Queensland Health
    Open grant
  • 1998 - 2006
    An integrated research program examining risk factors for psychoses
    Stanley Foundation Research Awards Program
    Open grant
  • 1997 - 1999
    A genetic study of schizophrenia in Fiji
    Scottish Rite Schizophrenia Research Program
    Open grant
  • 1997
    A molecular genetic linkage study of schizophrenia
    Ramaciotti Foundation
    Open grant
  • 1997
    A molecular genetic linkage study of Schizophrenia
    UQ Foundation
    Open grant
  • 1997 - 1999
    A molecular genetic linkage study of schizophrenia
    NHMRC Project Grant
    Open grant
  • 1996 - 1997
    Molecular genetic linkage study of schizophrenia
    Perpetual Trustee Company Limited
    Open grant
  • 1996 - 1997
    Schizophrenia Genetics Research Program : Hot spot mapping in an extended schizophrenia cohort
    Queensland Health
    Open grant
  • 1996 - 1997
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant

Availability

Professor Bryan Mowry is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Professor Bryan Mowry directly for media enquiries about:

  • Culture and psychiatry
  • Ethics - psychiatry
  • Genetics and mental illnesses
  • Health - mental
  • Mental illness and genetics
  • Psychiatric ethics
  • Psychiatry - trans-cultural
  • Schizophrenia
  • Trans-cultural psychiatry

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