
Overview
Background
Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.
The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.
Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia
Availability
- Professor Bryan Mowry is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists
Works
Search Professor Bryan Mowry’s works on UQ eSpace
2019
Journal Article
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, Laura M., Dobbyn, Amanda, Ruderfer, Douglas M., Hoffman, Gabriel, Wang, Weiqing, Pardiñas, Antonio F., Rajagopal, Veera M., Als, Thomas D., T. Nguyen, Hoang, Girdhar, Kiran, Boocock, James, Roussos, Panos, Fromer, Menachem, Kramer, Robin, Domenici, Enrico, Gamazon, Eric R., Purcell, Shaun, Johnson, Jessica S., Shah, Hardik R., Klein, Lambertus L., Dang, Kristen K., Logsdon, Benjamin A., Mahajan, Milind C., Mangravite, Lara M., Toyoshiba, Hiroyoshi, Gur, Raquel E., Hahn, Chang-Gyu, Schadt, Eric, Lewis, David A. ... Stahl, Eli A. (2019). Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics, 51 (4), 659-674. doi: 10.1038/s41588-019-0364-4
2019
Journal Article
Reply to: New meta- and mega-analyses of Magnetic Resonance Imaging findings in schizophrenia: do they really increase our knowledge about the nature of the disease process?
van Erp, Theo G.M., Walton, Esther, Hibar, Derrek P., Schmaal, Lianne, Jiang, Wenhao, Glahn, David C., Pearlson, Godfrey D., Yao, Nailin, Fukunaga, Masaki, Hashimoto, Ryota, Okada, Naohiro, Yamamori, Hidenaga, Clark, Vincent P., Mueller, Bryon A., de Zwarte, Sonja M.C., Ophoff, Roel A., van Haren, Neeltje E.M., Andreassen, Ole A., Gurholt, Tiril P., Gruber, Oliver, Kraemer, Bernd, Richter, Anja, Calhoun, Vince D., Crespo-Facorro, Benedicto, Roiz-Santiañez, Roberto, Tordesillas-Gutiérrez, Diana, Loughland, Carmel, Catts, Stanley, Fullerton, Janice M. ... Turner, Jessica A. (2019). Reply to: New meta- and mega-analyses of Magnetic Resonance Imaging findings in schizophrenia: do they really increase our knowledge about the nature of the disease process?. Biological Psychiatry, 85 (7), e35-e39. doi: 10.1016/j.biopsych.2018.10.003
2019
Journal Article
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, Denise, Connolly, Siobhan, Riley, Brien P., Kendler, Kenneth S., McCarthy, Shane E., McCombie, William R., Richards, Alex, Owen, Michael J., O'Donovan, Michael C., Walters, James, Donnelly, Peter, Bates, Lesley, Barroso, Ines, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N. A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C. ... Morris, Derek W. (2019). Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 180 (3), 223-231. doi: 10.1002/ajmg.b.32716
2019
Conference Publication
First genome-wide association study of schizophrenia in an Indian population reveals a novel susceptibility locus
Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Holliday, Elizabeth, Bakshi, Andrew, Jorde, Lynn, Brown, Matthew, Wray, Naomi, Suetani, Rachel, Giacomotto, Jean, Thara, Rangaswamy and Mowry, Bryan (2019). First genome-wide association study of schizophrenia in an Indian population reveals a novel susceptibility locus. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2018.08.017
2019
Journal Article
A polygenic resilience score moderates the genetic risk for schizophrenia
Hess, Jonathan L., Tylee, Daniel S., Mattheisen, Manuel, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Andreassen, Ole A, Arranz, Maria J, Bacanu, Silviu A, Bakker, Steven, Band, Gavin, Barroso, Ines, Begemann, Martin, Bellenguez, Céline, Belliveau, Richard A, Bender, Stephan, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Blackburn, Hannah, Blackwell, Jenefer M, Blackwood, Douglas H R, Bramon, Elvira, Brown, Matthew A ... Glatt, Stephen J. (2019). A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry, 26 (3), 800-815. doi: 10.1038/s41380-019-0463-8
2019
Conference Publication
Modelling the impact of schizophrenia gwas loci during human brain development using spatio-temporal gene expression data
Periyasamy, Sathish and Mowry, Bryan (2019). Modelling the impact of schizophrenia gwas loci during human brain development using spatio-temporal gene expression data. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2018.08.489
2018
Journal Article
Neural correlates of dynamic emotion perception in schizophrenia and the influence of prior expectations
Dzafic, Ilvana, Burianová, Hana, Martin, Andrew K. and Mowry, Bryan (2018). Neural correlates of dynamic emotion perception in schizophrenia and the influence of prior expectations. Schizophrenia Research, 202, 129-137. doi: 10.1016/j.schres.2018.06.015
2018
Journal Article
Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery
Kos, Mark Z., Duan, Jubao, Sanders, Alan R., Blondell, Lucy, Drigalenko, Eugene I., Carless, Melanie A., Gejman, Pablo V., Göring, Harald H. H., Gejman, P. V., Sanders, A. R., Duan, J., Levinson, D. F., Shi, J., Buccola, N. G., Mowry, B. J., Freedman, R., Olincy, A., Amin, F., Black, D. W., Silverman, J. M., Byerley, W. F., Cloninger, C. R. and Svrakic, D. M. (2018). Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery. Translational Psychiatry, 8 (1) 278. doi: 10.1038/s41398-018-0325-1
2018
Journal Article
Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model
Duan, Jubao, Göring, Harald H. H., Sanders, Alan R., Moy, Winton, Freda, Jessica, Drigalenko, Eugene I., Kos, Mark, He, Deli, Gejman, Pablo V., Gejman, P. V., MGS, Sanders, A. R., Duan, J., Levinson, D. F., Shi, J., Buccola, N. G., Mowry, B. J., Freedman, R., Olincy, A., Amin, F., Black, D. W., Silverman, J. M., Byerley, W. F., Cloninger, C. R. and Svrakic, D. M. (2018). Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model. Translational Psychiatry, 8 (1) 158. doi: 10.1038/s41398-018-0216-5
2018
Journal Article
Association between schizophrenia polygenic risk and neural correlates of emotion perception
Dzafic, Ilvana, Burianová, Hana, Periyasamy, Sathish and Mowry, Bryan (2018). Association between schizophrenia polygenic risk and neural correlates of emotion perception. Psychiatry research: Neuroimaging, 276, 33-40. doi: 10.1016/j.pscychresns.2018.04.005
2018
Journal Article
A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
LeBlanc, Marissa, Zuber, Verena, Thompson, Wesley K., Andreassen, Ole A., Frigessi, Arnoldo, Andreassen, Bettina Kulle, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T. R., Farh, Kai-How, Lee, Phil, Bulik-Sullivan, Brendan, Collier, David, Huang, Hailiang, Pers, Tune, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A., Bene, Judit, Bevilacqua, Elizabeth, Bigdeli, Tim B., Black, Donald W., Bruggeman, Richard ... Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (2018). A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework. BMC Genomics, 19 (1) 494. doi: 10.1186/s12864-018-4859-7
2018
Journal Article
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Boocock, James, Stahl, Eli A., Pavlides, Jennifer M. Whitehead, Mullins, Niamh, Charney, Alexander W., Ori, Anil P.S., Loohuis, Loes M. Olde, Domenici, Enrico, Di Florio, Arianna, Papiol, Sergi, Kalman, Janos L., Trubetskoy, Vassily, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Akil, Huda, Albani, Diego, Albus, Margot, Alda, Martin, Alexander, Madeline, Alliey-Rodriguez, Ney, Als, Thomas D., Amin, Farooq, Anjorin, Adebayo, Arranz, Maria J., Awasthi, Swapnil ... Kendler, Kenneth S. (2018). Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell, 173 (7), 1705-1715.e16. doi: 10.1016/j.cell.2018.05.046
2018
Journal Article
Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control cubjects via the enhancing neuro imaging genetics through meta analysis (ENIGMA) consortium
van Erp, Theo G. M., Walton, Esther, Hibar, Derrek P., Schmaal, Lianne, Jiang, Wenhao, Glahn, David C., Pearlson, Godfrey D., Yao, Nailin, Fukunaga, Masaki, Hashimoto, Ryota, Okada, Naohiro, Yamamori, Hidenaga, Bustillo, Juan R., Clark, Vincent P., Agartz, Ingrid, Mueller, Bryon A., Cahn, Wiepke, de Zwarte, Sonja M. C., Hulshoff Pol, Hilleke E., Kahn, René S., Ophoff, Roel A., van Haren, Neeltje E. M., Andreassen, Ole A., Dale, Anders M., Doan, Nhat Trung, Gurholt, Tiril P., Hartberg, Cecilie B., Haukvik, Unn K., Jørgensen, Kjetil N. ... Turner, Jessica A. (2018). Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control cubjects via the enhancing neuro imaging genetics through meta analysis (ENIGMA) consortium. Biological Psychiatry, 84 (9), 644-654. doi: 10.1016/j.biopsych.2018.04.023
2018
Journal Article
Replication of GWAS identified miR-137 and its target gene polymorphisms in Schizophrenia of South Indian population and meta-analysis with Psychiatric Genomics Consortium
Sudesh, Ravi, Thalamuthu, Anbupalam, John, Sujit, Thara, Rangaswamy, Mowry, Bryan and Munirajan, Arasamabattu Kannan (2018). Replication of GWAS identified miR-137 and its target gene polymorphisms in Schizophrenia of South Indian population and meta-analysis with Psychiatric Genomics Consortium. Schizophrenia Research, 199, 189-194. doi: 10.1016/j.schres.2018.03.028
2017
Journal Article
Correlates of employment interest among adults with schizophrenia
Westcott, Cassandra, Waghorn, Geoffrey, McLean, Duncan, Statham, Dixie and Mowry, Bryan (2017). Correlates of employment interest among adults with schizophrenia. International Journal of Therapy and Rehabilitation, 24 (12), 510-519. doi: 10.12968/ijtr.2017.24.12.510
2017
Journal Article
Genome-wide association study of male sexual orientation
Sanders, Alan R., Beecham, Gary W., Guo, Shengru, Dawood, Khytam, Rieger, Gerulf, Badner, Judith A., Gershon, Elliot S., Krishnappa, Ritesha S., Kolundzija, Alana B., Duan, Jubao, Shi, Jianxin, Levinson, Douglas F., Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Svrakic, Dragan M., Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Freedman, Robert, Gejman, Pablo V., Bailey, J. Michael, Martin, Eden R., MGS Collaboration and Mowry, Bryan J. (2017). Genome-wide association study of male sexual orientation. Scientific Reports, 7 (1) 16950. doi: 10.1038/s41598-017-15736-4
2017
Journal Article
Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese
Gratten, Jacob, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul J., Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jin, Zi-Bing, Li, Zhongshan, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, Mowry, Bryan J., Ran, Shu, Reutens, David C., Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn H. ... Fan, Dongsheng (2017). Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Medicine, 9 (97) 97, 97. doi: 10.1186/s13073-017-0487-0
2017
Journal Article
Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
Kelly, S., Jahanshad, N., Zalesky, A., Kochunov, P., Agartz, I., Alloza, C., Andreassen, O. A., Arango, C., Banaj, N., Bouix, S., Bousman, C. A., Brouwer, R. M., Bruggemann, J., Bustillo, J, Cahn, W., Calhoun, V., Cannon, D., Carr, V., Catts, S., Chen, J., Chen, J.-X., Chen, X., Chiapponi, C., Cho, K. l. K., Ciullo, V., Corvin, A. S., Crespo-Facorro, B., Cropley, V., De Rossi, P. ... Donohoe, G. (2017). Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group. Molecular Psychiatry, 23 (5), 1261-1269. doi: 10.1038/mp.2017.170
2017
Journal Article
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis
Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1
2017
Journal Article
Minor allele C of rs12807809 polymorphism in NRGN contributes to the severity of psychosis in patients with Schizophrenia in South Indian population
Sudesh, Ravi, Priyadarshini, Thirunavukkarasu, Preeti, Rajendran, John, Sujit, Thara, Rangaswamy, Mowry, Bryan and Munirajan, Arasamabattu Kannan (2017). Minor allele C of rs12807809 polymorphism in NRGN contributes to the severity of psychosis in patients with Schizophrenia in South Indian population. Neuroscience Letters, 649, 107-111. doi: 10.1016/j.neulet.2017.04.008
Funding
Past funding
Supervision
Availability
- Professor Bryan Mowry is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Completed supervision
-
2021
Doctor Philosophy
New technologies and models to investigate the functional role of neurexins in zebrafish
Principal Advisor
Other advisors: Dr Jean Giacomotto
-
2017
Doctor Philosophy
The Neuroimaging and Genetics of Emotion Perception in Schizophrenia
Principal Advisor
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2016
Doctor Philosophy
Contrasting the Expression of Psychotic Disorders in Ethnically Different Populations
Principal Advisor
Other advisors: Professor John McGrath
-
2015
Doctor Philosophy
Characterizing copy number variants in schizophrenia: a clinical, neuropsychological, and neuroimaging study.
Principal Advisor
Other advisors: Professor Gail Robinson
-
2015
Doctor Philosophy
Analysis of non-coding RNA expression in schizophrenia brain
Principal Advisor
Other advisors: Honorary Professor Jake Gratten
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2002
Doctor Philosophy
MOLECULAR CANDIDATES FOR SCHIZOPHRENIA
Principal Advisor
Other advisors: Professor John McGrath
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2012
Doctor Philosophy
Immune dysregulation in schizophrenia: Do some cases of schizophrenia have an autoimmune basis?
Associate Advisor
Other advisors: Emeritus Professor Michael Pender, Associate Professor Judith Greer
Media
Enquiries
Contact Professor Bryan Mowry directly for media enquiries about:
- Culture and psychiatry
- Ethics - psychiatry
- Genetics and mental illnesses
- Health - mental
- Mental illness and genetics
- Psychiatric ethics
- Psychiatry - trans-cultural
- Schizophrenia
- Trans-cultural psychiatry
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