Professor Bryan Mowry
Professor

Bryan Mowry

Email: 

Background

Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.

The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.

Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia

Availability

Professor Bryan Mowry is:
Available for supervision
Media expert

Fields of research

Clinical sciences Genetics Neurosciences

Qualifications

  • Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists

Search Professor Bryan Mowry’s works on UQ eSpace

280 works between 1985 and 2024
All (280) Journal Article (214) Book Chapter (4) Conference Publication (58) Other Outputs (4)

101 - 120 of 280 works

2014

Journal Article

DSM-IV "Criterion A" schizophrenia symptoms across ethnically different populations: evidence for differing psychotic symptom content or structural organization?

McLean, Duncan, Thara, Rangaswamy, John, Sujit, Barrett, Robert, Loa, Peter, McGrath, John and Mowry, Bryan (2014). DSM-IV "Criterion A" schizophrenia symptoms across ethnically different populations: evidence for differing psychotic symptom content or structural organization?. Culture, Medicine, and Psychiatry, 38 (3), 408-426. doi: 10.1007/s11013-014-9385-8

DSM-IV "Criterion A" schizophrenia symptoms across ethnically different populations: evidence for differing psychotic symptom content or structural organization?

2014

Journal Article

Cannabis abuse and age at onset in schizophrenia patients with large, rare copy number variants

Martin, Andrew Kenneth, Robinson, Gail, Reutens, David and Mowry, Bryan (2014). Cannabis abuse and age at onset in schizophrenia patients with large, rare copy number variants. Schizophrenia Research, 155 (1-3), 21-25. doi: 10.1016/j.schres.2014.03.004

Cannabis abuse and age at onset in schizophrenia patients with large, rare copy number variants

2014

Journal Article

Elevated levels of autoantibodies targeting the M1 muscarinic acetylcholine receptor and neurofilament medium in sera from subgroups of patients with schizophrenia

Jones, Amanda L., Mowry, Bryan J., McLean, Duncan E., Mantzioris, Basil X., Pender, Michael P. and Greer, Judith M. (2014). Elevated levels of autoantibodies targeting the M1 muscarinic acetylcholine receptor and neurofilament medium in sera from subgroups of patients with schizophrenia. Journal of Neuroimmunology, 269 (1-2), 68-75. doi: 10.1016/j.jneuroim.2014.02.008

Elevated levels of autoantibodies targeting the M1 muscarinic acetylcholine receptor and neurofilament medium in sera from subgroups of patients with schizophrenia

2014

Journal Article

Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia

Mulle, Jennifer Gladys, Pulver, Ann E., McGrath, John A., Wolyniec, Paula S., Dodd, Anne F., Cutler, David J., Sebat, Jonathan, Malhotra, Dheeraj, Nestadt, Gerald, Conrad, Donald F., Hurles, Matthew, Barnes, Chris P., Ikeda, Masashi, Iwata, Nakao, Levinson, Douglas F., Gejman, Pablo V., Sanders, Alan R., Duan, Jubao, Mitchell, Adele A., Peter, Inga, Sklar, Pamela, O'Dushlaine, Colm T., Grozeva, Detelina, O'Donovan, Michael C., Owen, Michael J., Hultman, Christina M., Kahler, Anna K., Sullivan, Patrick F., The Molecular Genetics of Schizophrenia Consortium ... Mowry, Bryan J. (2014). Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia. Biological Psychiatry, 75 (5), 371-377. doi: 10.1016/j.biopsych.2013.05.040

Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia

2014

Journal Article

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

Andreassen, O. A., Harbo, H. F., Wang, Y., Thompson, W. K., Schork, A. J., Mattingsdal, M., Zuber, V., Bettella, F., Ripke, S., Kelsoe, J. R., Kendler, K. S., O'Donovan, M. C., Sklar, P., The Psychiatric Genomics Consortium (PGC), Mowry, Bryan, McEvoy, L. K., Desikan, R. S., Lie, B. A., Djurovic, S. and Dale, A. M. (2014). Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Molecular Psychiatry, 20 (2), 207-214. doi: 10.1038/mp.2013.195

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

2014

Conference Publication

Characterizing rare copy number variants in schizophrenia: a clinical, cognitive, and neuroimaging study

Martin, Andrew K., Robinson, Gail A., Reutens, David C. and Mowry, Bryan (2014). Characterizing rare copy number variants in schizophrenia: a clinical, cognitive, and neuroimaging study. ICON 2014: XII International Conference on Cognitive Neuroscience, Brisbane, QLD, Australia, 27-31 July, 2014. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.fnhum.2015.217.00306

Characterizing rare copy number variants in schizophrenia: a clinical, cognitive, and neuroimaging study

2014

Journal Article

Theory of mind and the social brain: implications for understanding the genetic basis of schizophrenia

Martin, A. K., Robinson, G., Dzafic, I., Reutens, David and Mowry, Bryan (2014). Theory of mind and the social brain: implications for understanding the genetic basis of schizophrenia. Genes, Brain and Behavior, 13 (1), 104-117. doi: 10.1111/gbb.12066

Theory of mind and the social brain: implications for understanding the genetic basis of schizophrenia

2014

Book Chapter

Future directions in genetics of psychiatric disorders

Wray, Naomi R., Byrne, Enda M., Stringer, Sven and Mowry, Bryan J. (2014). Future directions in genetics of psychiatric disorders. Behavior genetics of psychopathology. (pp. 311-337) edited by Soo Hyun Rhee and Angelica Ronald. New York, NY, United States: Springer New York. doi: 10.1007/978-1-4614-9509-3_11

Future directions in genetics of psychiatric disorders

2014

Journal Article

Variability inworking memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway

Nicodemus, Kristin K., Hargreaves, April, Morris, Derek, Anney, Richard, Gill, Michael, Corvin, Aiden, Donohoe, Gary, for the Schizophrenia Psychiatric Genome-wide Association Study (GWAS) Consortium and The Wellcome Trust Case Control Consortium 2, Brown, Matthew A., Mowry, Bryan and McLean, Duncan E. (2014). Variability inworking memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway. JAMA Psychiatry, 71 (7), 778-785. doi: 10.1001/jamapsychiatry.2014.528

Variability inworking memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway

2014

Journal Article

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Catts, Stanley V., Gratten, Jacob, Lee, S. Hong, Wray, Naomi R., Visscher, Peter M., Mowry, Bryan J., Nertney, Deborah A., Psychosis Endophenotypes International Consortium and Wellcome Trust Case-Control Consortium 2 (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511 (7510), 421-427. doi: 10.1038/nature13595

Biological insights from 108 schizophrenia-associated genetic loci

2013

Journal Article

Transcriptome study of differential expression in schizophrenia

Sanders, Alan R., Goering, Harald H. H., Duan, Jubao, Drigalenko, Eugene I., Moy, Winton, Freda, Jessica, He, Deli, Shi, Jianxin, Gejman, Pablo V., Molecular Genetics of Schizophrenia (MGS) and Mowry, Bryan (2013). Transcriptome study of differential expression in schizophrenia. Human Molecular Genetics, 22 (24), 5001-5014. doi: 10.1093/hmg/ddt350

Transcriptome study of differential expression in schizophrenia

2013

Journal Article

Schizophrenia genetic variants are not associated with intelligence

Terwisscha van Scheltinga, A. F., Bakker, S. C., Van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Cahn, W., Ripke, S., Ophoff, R. A., Kahn, R. S., Psychiatric Genomic-Wide Association Study (GWAS) Consortium, Visscher, P. M., Mowry, B. J., Brown, M. A., McGrath, J. J. and McLean, Duncan E. (2013). Schizophrenia genetic variants are not associated with intelligence. Psychological Medicine, 43 (12), 2563-2570. doi: 10.1017/S0033291713000196

Schizophrenia genetic variants are not associated with intelligence

2013

Journal Article

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Ripke, Stephan, O'Dushlaine, Colm, Chambert, Kimberly, Moran, Jennifer L., Kaehler, Anna K., Akterin, Susanne, Bergen, Sarah E., Collins, Ann L., Crowley, James J., Fromer, Menachem, Kim, Yunjung, Lee, Sang Hong, Magnusson, Patrik K. E., Sanchez, Nick, Stahl, Eli A., Williams, Stephanie, Wray, Naomi R., Xia, Kai, Bettella, Francesco, Borglum, Anders D., Bulik-Sullivan, Brendan K., Cormican, Paul, Craddock, Nick, de Leeuw, Christiaan, Durmishi, Naser, Gill, Michael, Golimbet, Vera, Hamshere, Marian L., Holmans, Peter ... Brown, Matthew A (2013). Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature Genetics, 45 (10), 1150-U282. doi: 10.1038/ng.2742

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

2013

Journal Article

Additive genetic variation in schizophrenia risk is shared by populations of African and European descent

de Candia, Teresa R., Lee, S. Hong, Yang, Jian, Browning, Brian L., Gejman, Pablo V., Levinson, Douglas F., Mowry, Bryan J., Hewitt, Bryan J., Goddard, Michael E., O'Donovan, Michael C., Purcell, Shaun M., Posthuma, Danielle, The International Schizophrenia Consortium, The Molecular Genetics of Schizophrenia Collaboration, Visscher, Peter M., Wray, Naomi R. and Keller, Matthew C. (2013). Additive genetic variation in schizophrenia risk is shared by populations of African and European descent. American Journal of Human Genetics, 93 (3), 463-470. doi: 10.1016/j.ajhg.2013.07.007

Additive genetic variation in schizophrenia risk is shared by populations of African and European descent

2013

Journal Article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. Hong, Ripke, Stephan, Neale, Benjamin M., Faraone, Stephen V., Purcell, Shaun M., Perlis, Roy H., Mowry, Bryan J., Thapar, Anita, Goddard, Michael E., Witte, John S., Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A., Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E., Asherson, Philip, Azevedo, Maria H., Backlund, Lena, Badner, Judith A., Bailey, Anthony J., Banaschewski, Tobias, Barchas, Jack D., Barnes, Michael R., Barrett, Thomas B., Bass, Nicholas ... Wray, Naomi R. (2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics, 45 (9), 984-995. doi: 10.1038/ng.2711

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

2013

Journal Article

Comparing schizophrenia symptoms in the Iban of Sarawak with other populations to elucidate clinical heterogeneity

McLean, Duncan, Barrett, Robert, Loa, Peter, Thara, Rangaswamy, John, Sujit, McGrath, John, Gratten, Jake and Mowry, Bryan (2013). Comparing schizophrenia symptoms in the Iban of Sarawak with other populations to elucidate clinical heterogeneity. Asia-Pacific Psychiatry, 7 (1), 36-44. doi: 10.1111/appy.12093

Comparing schizophrenia symptoms in the Iban of Sarawak with other populations to elucidate clinical heterogeneity

2013

Journal Article

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

Schork, Andrew J., Thompson, Wesley K., Pham, Phillip, Torkamani, Ali, Roddey, J. Cooper, Sullivan, Patrick F., Kelsoe, John R., O'Donovan, Michael C., Furberg, Helena, The Tobacco and Genetics Consortium, The Bipolar Disorder Psychiatric Genomics Consortium, The Schizophrenia Psychiatric Genomics Consortium, Schork, Nicholas J., Andreassen, Ole A., Dale, Anders M., McGrath, John J., Mowry, Bryan and Visscher, Peter (2013). All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PloS Genetics, 9 (4) e1003449, e1003449. doi: 10.1371/journal.pgen.1003449

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

2013

Journal Article

Genetic schizophrenia risk variants jointly modulate total brain and white matter volume

Terwisscha van Scheltinga, Afke F., Bakker, Steven C., van Haren, Neeltje E. M., Derks, Eske M., Buizer-Voskamp, Jacobine E., Boos, Heleen B. M., Cahn, Wiepke, Pol, Hilleke E. Hulshoff, Ripke, Stephan, Ophoff, Roel A., Kahn, Rene S., Psychiatric Genome-wide Association Study Consortium, Mowry, Bryan J., McGrath, John J ., Nertney, Deborah A ., Brown, Matthew A., Danoy, Patrick A., Catts, Stanley V. and McLean, Duncan E. (2013). Genetic schizophrenia risk variants jointly modulate total brain and white matter volume. Biological Psychiatry, 73 (6), 525-531. doi: 10.1016/j.biopsych.2012.08.017

Genetic schizophrenia risk variants jointly modulate total brain and white matter volume

2013

Journal Article

Correction: Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis (PLoS ONE)

Derks, Eske M., Vorstman, Jacob A. S., Ripke, Stephan, Kahn, Rene S., The Schizophrenia Psychiatric Genomic Consortium, Mowry, Bryan and Ophoff, Roel A. (2013). Correction: Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis (PLoS ONE). PLoS ONE, 8 (3). doi: 10.1371/annotation/6ff0353a-cc91-4d12-896a-d1de0dcb0fe0

Correction: Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis (PLoS ONE)

2013

Journal Article

Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

Gratten, Jacob, Visscher, Peter M., Mowry, Bryan J. and Wray, Naomi R. (2013). Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease. Nature Genetics, 45 (3), 234-238. doi: 10.1038/ng.2555

Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

Past funding

  • 2022 - 2023
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish (NHMRC Project Grant administered by Griffith University)
    Griffith University
    Open grant
  • 2022
    Genotype Imputation Resources for Productive Genetic Disease Studies of Indigenous Oceanic Sub-Populations
    NHMRC IDEAS Grants
    Open grant
  • 2019 - 2022
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish.
    NHMRC Project Grant
    Open grant
  • 2016 - 2021
    Investigating the aetiopathogenic role of autoantibodies against the M1 muscarinic acetylcholine receptor in patients with first episode of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Using the Zebrafish to fight psychiatric disorders. From proof-of-principle to new insights and treatments
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2014 - 2016
    Dissecting the role of RYK in cortical neuron specification and schizophrenia
    NHMRC Project Grant
    Open grant
  • 2014 - 2018
    Genetic analysis of de novo and inherited exome variation in schizophrenia
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Statistical analyses of whole genome genotype data to better understand psychiatric disorders
    NHMRC Project Grant
    Open grant
  • 2012 - 2024
    Genetics of Schizophrenia Research Collaboration Programme
    West Moreton Hospital and Health Service
    Open grant
  • 2012
    Genetics of Schizophrenia Research Collaboration Programme
    Queensland Health
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2012
    Establishing a UWA-UQ network for collaboration in Autism Research
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2010
    High performance computing cluster to expand research capacity in neuroscience modelling, imaging and bioinformatics
    NHMRC Equipment Grant
    Open grant
  • 2010 - 2013
    Identifying eQTLs and endophenotyping known CNVs in a large Australian schizophrenia sample
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Linkage and association studies of schizophrenia in an isolated population
    NHMRC Project Grant
    Open grant
  • 2010
    Next-generation DNA sequencer to accelerate discovery in molecular and cellular research programs at QBI
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2014
    Studying the molecular basis of schizophrenia in a large, globally competitive Indian sample
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    QCMHR Operational (Genetics Laboratory Programme Funding)
    Queensland Health
    Open grant
  • 2006 - 2008
    Adiponectin - Multimerization, Secretion and Action
    NHMRC Project Grant
    Open grant
  • 2006
    Genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2003 - 2006
    Structural And Diffusion Tensor Neuroimaging In Twins Concordant And Discordant For Psychosis
    NHMRC Project Grant
    Open grant
  • 2002 - 2003
    Australian Psychotic Twins Study - MRI Research
    Schizophrenia Fellowship of South Qld Inc
    Open grant
  • 2000 - 2001
    A genetic study of schizophrenia in regional Tasmania: Initial genotyping of the first large pedigree
    Ramaciotti Foundation
    Open grant
  • 2000
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 1999 - 2003
    Molecular genetics of Schizophrenia
    United States National Institutes of Health
    Open grant
  • 1999 - 2001
    A Genetic Study of Schizophrenia in the Iban of Sarawak
    NHMRC Project Grant
    Open grant
  • 1999
    The molecular genetics of schizophrenia (2)
    Garvan Institute
    Open grant
  • 1998 - 2012
    QCMHR Operational (Genetics Research Project)
    Queensland Health
    Open grant
  • 1998 - 2006
    An integrated research program examining risk factors for psychoses
    Stanley Foundation Research Awards Program
    Open grant
  • 1997 - 1999
    A genetic study of schizophrenia in Fiji
    Scottish Rite Schizophrenia Research Program
    Open grant
  • 1997
    A molecular genetic linkage study of Schizophrenia
    UQ Foundation
    Open grant
  • 1997 - 1999
    A molecular genetic linkage study of schizophrenia
    NHMRC Project Grant
    Open grant
  • 1997
    A molecular genetic linkage study of schizophrenia
    Ramaciotti Foundation
    Open grant
  • 1996 - 1997
    Molecular genetic linkage study of schizophrenia
    Perpetual Trustee Company Limited
    Open grant
  • 1996 - 1997
    Schizophrenia Genetics Research Program : Hot spot mapping in an extended schizophrenia cohort
    Queensland Health
    Open grant
  • 1996 - 1997
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant

Availability

Professor Bryan Mowry is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Professor Bryan Mowry directly for media enquiries about:

  • Culture and psychiatry
  • Ethics - psychiatry
  • Genetics and mental illnesses
  • Health - mental
  • Mental illness and genetics
  • Psychiatric ethics
  • Psychiatry - trans-cultural
  • Schizophrenia
  • Trans-cultural psychiatry

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