Professor Bryan Mowry
Professor

Bryan Mowry

Email: 

Background

Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.

The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.

Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia

Availability

Professor Bryan Mowry is:
Available for supervision
Media expert

Fields of research

Clinical sciences Genetics Neurosciences

Qualifications

  • Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists

Search Professor Bryan Mowry’s works on UQ eSpace

280 works between 1985 and 2024
All (280) Journal Article (214) Book Chapter (4) Conference Publication (58) Other Outputs (4)

161 - 180 of 280 works

2009

Journal Article

Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms

Holmans, PA, Riley, B, Pulver, AE, Owen, MJ, Wildenauer, DB, Gejman, PV, Mowry, Bryan, Laurent, C, Kendler, KS, Nestadt, G, Williams, NM, Schwab, SG, Sanders, AR, Nertney, D, Mallet, J, Wormley, B, Lasseter, VK, O'Donovan, MC, Duan, J, Albus, M, Alexander, M, Godard, S, Ribble, R, Liang, KY, Norton, N, Maier, W, Papadimitriou, G, Walsh, D, Jay, M ... Levinson, DF (2009). Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms. Molecular Psychiatry, 14 (8), 786-795. doi: 10.1038/mp.2009.11

Genomewide linkage scan of schizophrenia in a large multicenter pedigree sample using single nucleotide polymorphisms

2009

Journal Article

Fine-scaled human genetic structure revealed by SNP microarrays

Xing, J. C., Watkins, W. S., Witherspoon, D. J., Zhang, Y. H., Guthery, S. L., Thara, R., Mowry, B. J., Bulayeva, K., Weiss, R. B. and Jorde, L. B. (2009). Fine-scaled human genetic structure revealed by SNP microarrays. Genome Research, 19 (5), 815-825. doi: 10.1101/gr.085589.108

Fine-scaled human genetic structure revealed by SNP microarrays

2009

Journal Article

CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophrenia

Jones, Amanda L., Holliday, Elizabeth G., Mowry, Bryan J., McLean, Duncan E., McGrath, John J., Pender, Michael P. and Greer, Judith M. (2009). CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophrenia. Brain Behavior and Immunity, 23 (3), 347-350. doi: 10.1016/j.bbi.2008.09.008

CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophrenia

2009

Conference Publication

A Database of Comprehensive Clinical, Endophenotypic and Genetic Data for Aetiological Studies of Schizophrenia

Carr, Vaughan, Loughland, C., Catts, S., Henskens, F., Jablensky, A., Michie, P., Mowry, B., Pantelis, C., Schall, U. and Scott, R. (2009). A Database of Comprehensive Clinical, Endophenotypic and Genetic Data for Aetiological Studies of Schizophrenia. 12th International Congress on Schizophrenia Research, San Diego Ca, Mar 28-Apr 01, 2009. OXFORD: OXFORD UNIV PRESS.

A Database of Comprehensive Clinical, Endophenotypic and Genetic Data for Aetiological Studies of Schizophrenia

2009

Journal Article

Strong Evidence for a Novel Schizophrenia Risk Locus on Chromosome 1p31.1 in Homogeneous Pedigrees From Tamil Nadu, India

Holliday, EG, Nyholt, DR, Tirupati, S, John, S, Ramachandran, P, Ramamurti, M, Ramadoss, AJ, Jeyagurunathan, A, Kottiswaran, S, Smith, HJ, Filippich, C, Nertney, DA, Nancarrow, DJ, Hayward, NK, Watkins, WS, Jorde, LB, Thara, R and Mowry, BJ (2009). Strong Evidence for a Novel Schizophrenia Risk Locus on Chromosome 1p31.1 in Homogeneous Pedigrees From Tamil Nadu, India. AMERICAN JOURNAL OF PSYCHIATRY, 166 (2), 206-215. doi: 10.1176/appi.ajp.2008.08030442

Strong Evidence for a Novel Schizophrenia Risk Locus on Chromosome 1p31.1 in Homogeneous Pedigrees From Tamil Nadu, India

2009

Journal Article

Design and clinical characteristics of a homogeneous schizophrenia pedigree sample from Tamil Nadu, India

Thara, R, Srinivasan, T, John, S, Nancarrow, D, Chant, D, Holliday, E and Mowry, B (2009). Design and clinical characteristics of a homogeneous schizophrenia pedigree sample from Tamil Nadu, India. Australian And New Zealand Journal of Psychiatry, 43 (6) PII 911161742, 561-570. doi: 10.1080/00048670902873631

Design and clinical characteristics of a homogeneous schizophrenia pedigree sample from Tamil Nadu, India

2009

Conference Publication

IT support for the Australian Schizophrenia Research Bank

Henskens, F. A., Loughland, C. A., Aphale, M. S., Paul, D., Richards, J. A., Rasser, P., Carr, V. J., Catts, S. V., Jablensky, A., Michie, P. T., Mowry, B. J., Pantelis, C., Schall, U. and Scott, R. J. (2009). IT support for the Australian Schizophrenia Research Bank. 2nd International Conference on Health Informatics (HEALTHINF 2009), Oporto, Portugal, 14-17 January 2009. Setubal, Portugal: INSTICC.

IT support for the Australian Schizophrenia Research Bank

2009

Journal Article

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

Psychiatric GWAS Consortium Coordinating Committee, Martin, N., Wray, N., Mowry, B. and Holliday, E. (2009). Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders. American Journal of Psychiatry, 166 (5), 540-556. doi: 10.1176/appi.ajp.2008.08091354

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

2008

Journal Article

Meta-analysis of 32 genome-wide linkage studies of schizoph

Ng, M. Y. M., Levinson, D. F., Faraone S. V., Suarez, B. K., DeLisi, L. E., Arinami, T., Riley, B., Paunio, T., Pulver, A. E., Irmansyah, Holmans,P. A., Escamilla, M., Wildenauer, DB, Williams, N. M., Laurent, C., Mowry, Bryan, Brzustowicz, L. M., Maziade, M., Sklar, P., Garver, D. L., Abecasi, G. R., Lerer, B., Fallin, M. D., Gurling, H. M. D., Gejman, P. V., Lindholm, E., Moises, H. W., Byerley, W., Wijsman, E. M. ... Lewis, C. M. (2008). Meta-analysis of 32 genome-wide linkage studies of schizoph. Molecular Psychiatry, 14 (8), 774-785. doi: 10.1038/mp.2008.135

Meta-analysis of 32 genome-wide linkage studies of schizoph

2008

Journal Article

Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms

Watkins, W. S., Thara, R., Mowry, B. J., Zhang, Y., Witherspoon, D. J., Tolpinrud, W., Bamshad, M. J., Tirupati, S., Padmavati, R., Smith, H., Nancarrow, D., Filippich, C. and Jorde, L. B. (2008). Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms. BMC Genetics, 9 (1) 86. doi: 10.1186/1471-2156-9-86

Genetic variation in South Indian castes: evidence from Y-chromosome, mitochondrial, and autosomal polymorphisms

2008

Journal Article

A Reanalysis of 409 European-Ancestry and African American Schizophrenia Pedigrees Reveals Significant Linkage to 8p23.3 With Evidence of Locus Heterogeneity

Holliday, E. G., Mowry, B. J. and Nyholt, D. R. (2008). A Reanalysis of 409 European-Ancestry and African American Schizophrenia Pedigrees Reveals Significant Linkage to 8p23.3 With Evidence of Locus Heterogeneity. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 147B (7), 1080-1088. doi: 10.1002/ajmg.b.30722

A Reanalysis of 409 European-Ancestry and African American Schizophrenia Pedigrees Reveals Significant Linkage to 8p23.3 With Evidence of Locus Heterogeneity

2008

Journal Article

Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2

O'Donovan, M. C., Norton, N., Williams, H., Peirce, T., Moskvina, V., Nikolov, I., Hamshere, M., Carroll, L., Georgieva, L., Dwyer, S., Holmans, P., Marchini, J. L., Spencer, C. C. A., Howie, B., Leung, H-T, Giegling, I., Hartmann, A. M., Moeller, H.-J., Morris, D. W., Shi, Y., Feng, G., Hoffmann, P., Propping, P., Vasilescu, C., Maier, W., Rietschel, M., Zammit, S., Schumacher, J., Quinn, E. M. ... Mowry, B.J. (2008). Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2. Molecular Psychiatry, 14 (1), 30-36. doi: 10.1038/mp.2008.108

Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2

2008

Journal Article

Identification of loci associated with schizophrenia by genome-wide association and follow-up

Donovan, Michael C., Craddock, Nicholas, Norton, Nadine, Williams, Hywel, Peirce, Timothy, Moskvina, Valentina, Nikolov, Ivan, Hamshere, Marian, Carroll, Liam, Georgieva, Lyudmila, Dwyer, Sarah, Holmans, Peter, Marchini, Johnthan L., Spencer, Chris C. A., Howie, Bryan, Leung, Hin-Tak, Hartmann, Annette M., Moller, Hans-Jurgen, Morris, Derek W., Shi, YongYong, Feng, GuoYin, Hoffmann, Per, Propping, Peter, Vasilescu, Catalina, Maier, Wolfgang, Rietschel, Marcella, Zammit, Stanley, Schumacher, Johannes, Quinn, Emma M. ... Mowry, Bryan (2008). Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nature Genetics, 40 (9), 1053-1055. doi: 10.1038/ng.201

Identification of loci associated with schizophrenia by genome-wide association and follow-up

2008

Journal Article

Fibroblast and lymphoblast gene expression profiles in schizophrenia: Are non-neural cells informative?

Matigian, Nicholas A., McCurdy, Richard D., Feron, Francois, Perry, Christopher, Smith, Heather, Filippich, Cheryl, McLean, Duncan, McGrath, John J., Mackay-Sim, Alan, Mowry, Bryan and Hayward, Nicholas K. (2008). Fibroblast and lymphoblast gene expression profiles in schizophrenia: Are non-neural cells informative?. PLoS One, 3 (6) e2412, e2412-1-e2412-5. doi: 10.1371/journal.pone.0002412

Fibroblast and lymphoblast gene expression profiles in schizophrenia: Are non-neural cells informative?

2008

Journal Article

No significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics

Sanders, Alan R, Duan, Jubao, Levinson, Douglas F, Jianxin, Shi, He, Deli, Hou, Cuiping, Burrell, Gregory J, Rice, John P, Nertney, Deborah A, Olincy, Ann, Rozic, Pablo, Vinogradov, Sophia, Buccola, Nancy, G and Mowry, Bryan (2008). No significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics. American Journal of Psychiatry, 165 (4), 497-506. doi: 10.1176/appi.ajp.2007.07101573

No significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics

2008

Conference Publication

The Australian Schizophrenia Research Bank (ASRB) computer-based Clinical Assessment Software (CAS): Development and application

Richards, Jaci, Loughland, Carmel M., Aphale, Mukta, Henskens, Frans, Carr, Vaughan J., Catts, Stanley V., Jablensky, Assen, Mitchie, Patricia T., Mowry, Bryan J., Pantelis, Christos, Schall, Ulrich, Scott, Rodney J. and Lewin, Terry J. (2008). The Australian Schizophrenia Research Bank (ASRB) computer-based Clinical Assessment Software (CAS): Development and application. Australian Society for Psychiatric Research (ASPR) Annual Conference 2008., Newcastle, Australia, 3-5 December 2008. Abingdon, UK: Informa Healthcare. doi: 10.1080/00048670802549646

The Australian Schizophrenia Research Bank (ASRB) computer-based Clinical Assessment Software (CAS): Development and application

2008

Conference Publication

A progress report on the Australian Schizophrenia Research Bank

Carr, V., Loughlan, C., Catts, S., Henskens, F., Jablensky, A., Michie, P., Mowry, B., Pantelis, C., Schall, U. and Scott, R. (2008). A progress report on the Australian Schizophrenia Research Bank. 10th Australasian Schizophrenia Conference, Melbourne, Australia, 23-24 October 2008. Melbourne, Australia: Informa Healthcare. doi: 10.1080/00048670802441851

A progress report on the Australian Schizophrenia Research Bank

2007

Journal Article

Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signaling pathway

Matigian, N., Windus, L., Smith, H., Fillipich, C., Pantelis, C., McGrath, J. J., Mowry, B. and Hayward, N. (2007). Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signaling pathway. Molecular Psychiatry, 12 (9), 815-825. doi: 10.1038/sj.mp.4001998

Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signaling pathway

2007

Journal Article

Replicated effects of sex and genotype on gene expression in human lymphoblastoid cell lines

McRae, A. F., Matigian, N. A., Vadlamudi, L., Mulley, J. C., Mowry, B., Martin, N. G., Berkovic, S. F., Hayward, N. K. and Visscher, P. M. (2007). Replicated effects of sex and genotype on gene expression in human lymphoblastoid cell lines. Human Molecular Genetics, 16 (4), 364-373. doi: 10.1093/hmg/ddl456

Replicated effects of sex and genotype on gene expression in human lymphoblastoid cell lines

2007

Conference Publication

An overview of the Australian schizophrenia research bank: Linking brain function and structure with genetics in a large sample of schizophrenia cases and controls

Carr, V., Schall, U., Michie, P., Scott, R., Jablenski, A., Mowry, B., Catts, S., Henskens, F. and Pantelis, C. (2007). An overview of the Australian schizophrenia research bank: Linking brain function and structure with genetics in a large sample of schizophrenia cases and controls. World Psychiatric Association International Congress 2007, Melbourne, Australia, 28 November-2 December 2007. Abingdon, England: Informa Healthcare. doi: 10.1080/00048670701757076

An overview of the Australian schizophrenia research bank: Linking brain function and structure with genetics in a large sample of schizophrenia cases and controls

Past funding

  • 2022 - 2023
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish (NHMRC Project Grant administered by Griffith University)
    Griffith University
    Open grant
  • 2022
    Genotype Imputation Resources for Productive Genetic Disease Studies of Indigenous Oceanic Sub-Populations
    NHMRC IDEAS Grants
    Open grant
  • 2019 - 2022
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish.
    NHMRC Project Grant
    Open grant
  • 2016 - 2021
    Investigating the aetiopathogenic role of autoantibodies against the M1 muscarinic acetylcholine receptor in patients with first episode of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Using the Zebrafish to fight psychiatric disorders. From proof-of-principle to new insights and treatments
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2014 - 2016
    Dissecting the role of RYK in cortical neuron specification and schizophrenia
    NHMRC Project Grant
    Open grant
  • 2014 - 2018
    Genetic analysis of de novo and inherited exome variation in schizophrenia
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Statistical analyses of whole genome genotype data to better understand psychiatric disorders
    NHMRC Project Grant
    Open grant
  • 2012 - 2024
    Genetics of Schizophrenia Research Collaboration Programme
    West Moreton Hospital and Health Service
    Open grant
  • 2012
    Genetics of Schizophrenia Research Collaboration Programme
    Queensland Health
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2012
    Establishing a UWA-UQ network for collaboration in Autism Research
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2010
    High performance computing cluster to expand research capacity in neuroscience modelling, imaging and bioinformatics
    NHMRC Equipment Grant
    Open grant
  • 2010 - 2013
    Identifying eQTLs and endophenotyping known CNVs in a large Australian schizophrenia sample
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Linkage and association studies of schizophrenia in an isolated population
    NHMRC Project Grant
    Open grant
  • 2010
    Next-generation DNA sequencer to accelerate discovery in molecular and cellular research programs at QBI
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2014
    Studying the molecular basis of schizophrenia in a large, globally competitive Indian sample
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    QCMHR Operational (Genetics Laboratory Programme Funding)
    Queensland Health
    Open grant
  • 2006 - 2008
    Adiponectin - Multimerization, Secretion and Action
    NHMRC Project Grant
    Open grant
  • 2006
    Genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2003 - 2006
    Structural And Diffusion Tensor Neuroimaging In Twins Concordant And Discordant For Psychosis
    NHMRC Project Grant
    Open grant
  • 2002 - 2003
    Australian Psychotic Twins Study - MRI Research
    Schizophrenia Fellowship of South Qld Inc
    Open grant
  • 2000 - 2001
    A genetic study of schizophrenia in regional Tasmania: Initial genotyping of the first large pedigree
    Ramaciotti Foundation
    Open grant
  • 2000
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 1999 - 2003
    Molecular genetics of Schizophrenia
    United States National Institutes of Health
    Open grant
  • 1999 - 2001
    A Genetic Study of Schizophrenia in the Iban of Sarawak
    NHMRC Project Grant
    Open grant
  • 1999
    The molecular genetics of schizophrenia (2)
    Garvan Institute
    Open grant
  • 1998 - 2012
    QCMHR Operational (Genetics Research Project)
    Queensland Health
    Open grant
  • 1998 - 2006
    An integrated research program examining risk factors for psychoses
    Stanley Foundation Research Awards Program
    Open grant
  • 1997 - 1999
    A genetic study of schizophrenia in Fiji
    Scottish Rite Schizophrenia Research Program
    Open grant
  • 1997
    A molecular genetic linkage study of Schizophrenia
    UQ Foundation
    Open grant
  • 1997 - 1999
    A molecular genetic linkage study of schizophrenia
    NHMRC Project Grant
    Open grant
  • 1997
    A molecular genetic linkage study of schizophrenia
    Ramaciotti Foundation
    Open grant
  • 1996 - 1997
    Molecular genetic linkage study of schizophrenia
    Perpetual Trustee Company Limited
    Open grant
  • 1996 - 1997
    Schizophrenia Genetics Research Program : Hot spot mapping in an extended schizophrenia cohort
    Queensland Health
    Open grant
  • 1996 - 1997
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant

Availability

Professor Bryan Mowry is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Professor Bryan Mowry directly for media enquiries about:

  • Culture and psychiatry
  • Ethics - psychiatry
  • Genetics and mental illnesses
  • Health - mental
  • Mental illness and genetics
  • Psychiatric ethics
  • Psychiatry - trans-cultural
  • Schizophrenia
  • Trans-cultural psychiatry

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