Professor Bryan Mowry
Professor

Bryan Mowry

Email: 

Background

Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.

The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.

Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia

Availability

Professor Bryan Mowry is:
Available for supervision
Media expert

Fields of research

Clinical sciences Genetics Neurosciences

Qualifications

  • Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists

Search Professor Bryan Mowry’s works on UQ eSpace

280 works between 1985 and 2024
All (280) Journal Article (214) Book Chapter (4) Conference Publication (58) Other Outputs (4)

121 - 140 of 280 works

2013

Journal Article

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

Andreassen, Ole A., Djurovic, Srdjan, Thompson, Wesley K., Schork, Andrew J., Kendler, Kenneth S., O'Donovan, Michael C., Rujescu, Dan, Werge, Thomas, van de Bunt, Martijn, Morris, Andrew P., McCarthy, Mark I., Roddey, J. Cooper, McEvoy, Linda K., Desikan, Rahul S., Dale, Anders M., International Consortium for Blood Pressure GWAS and Mowry, Bryan (2013). Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. American Journal of Human Genetics, 92 (2), 197-209. doi: 10.1016/j.ajhg.2013.01.001

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

2013

Journal Article

Will brain cells derived from induced pluripotent stem cells or directly converted from somatic cells (iNs) be useful for schizophrenia research?

Filippich, Cheryl, Wolvetang, Ernst J. and Mowry, Bryan J. (2013). Will brain cells derived from induced pluripotent stem cells or directly converted from somatic cells (iNs) be useful for schizophrenia research?. Schizophrenia Bulletin, 39 (5), 948-954. doi: 10.1093/schbul/sbt103

Will brain cells derived from induced pluripotent stem cells or directly converted from somatic cells (iNs) be useful for schizophrenia research?

2012

Journal Article

Genome-Wide Association Study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms

Fanous, Ayman H., Zhou, Baiyu, Aggen, Steven H., Bergen, Sarah E., Amdur, Richard L., Duan, Jubao, Sanders, Alan R., Shi, Jianxin, Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Freedman, Robert, Dudbridge, Frank, Holmans, Peter A., Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, Ripke, Stephan, Gejman, Pablo V., Kendler, Kenneth S. and Levinson, Douglas F. (2012). Genome-Wide Association Study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms. American Journal of Psychiatry, 169 (12), 1309-1317. doi: 10.1176/appi.ajp.2012.12020218

Genome-Wide Association Study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms

2012

Journal Article

Hybridization-based reconstruction of small non-coding RNA transcripts from deep sequencing data

Ragan, Chikako, Mowry, Bryan J. and Bauer, Denis C. (2012). Hybridization-based reconstruction of small non-coding RNA transcripts from deep sequencing data. Nucleic Acids Research, 40 (16), 7633-7643. doi: 10.1093/nar/gks505

Hybridization-based reconstruction of small non-coding RNA transcripts from deep sequencing data

2012

Journal Article

Genome-Wide Association Study of Multiplex Schizophrenia Pedigrees

Levinson, Douglas F., Shi, Jianxin, Wang, Kai, Oh, Sang, Riley, Brien, Pulver, Ann E., Wildenauer, Dieter B., Laurent, Claudine, Mowry, Bryan J., Gejman, Pablo V., Owen, Michael J., Kendler, Kenneth S., Nestadt, Gerald, Schwab, Sibylle G., Mallet, Jacques, Nertney, Deborah, Sanders, Alan R., Williams, Nigel M., Wormley, Brandon, Lasseter, Virginia K., Albus, Margot, Godard-Bauche, Stephanie, Alexander, Madeline, Duan, Jubao, O'Donovan, Michael C., Walsh, Dermot, O'Neill, Anthony, Papadimitriou, George N., Dikeos, Dimitris ... Holmans, Peter A. (2012). Genome-Wide Association Study of Multiplex Schizophrenia Pedigrees. American Journal of Psychiatry, 169 (9), 963-973. doi: 10.1176/appi.ajp.2012.11091423

Genome-Wide Association Study of Multiplex Schizophrenia Pedigrees

2012

Journal Article

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

Derks, Eske M., Vorstman, Jacob A. S., Ripke, Stephan, Kahn, Rene S., The Schizophrenia Psychiatric Genomic Consortium, Mowry, Bryan and Ophoff, Roel A. (2012). Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis. PLoS One, 7 (6) e37852, e37852.1-e37852.7. doi: 10.1371/journal.pone.0037852

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis

2012

Journal Article

The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants

Mowry, B. J. and Gratten, J. (2012). The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants. Molecular Psychiatry, 18 (1), 38-52. doi: 10.1038/mp.2012.34

The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants

2012

Journal Article

Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26

McAuley, Erica Z., Scimone, Anna, Tiwari, Yash, Agahi, Giti, Mowry, Bryan J., Holliday, Elizabeth G., Donald, Jennifer A., Weickert, Cynthia Shannon, Mitchell, Phillip B., Schofield, Peter R. and Fullerton, Janice M. (2012). Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26. Plos One, 7 (5) e38172, e38172.1-e38172.10. doi: 10.1371/journal.pone.0038172

Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26

2012

Journal Article

Refining clinical phenotypes by contrasting ethnically different populations with schizophrenia from Australia, India and Sarawak

McLean, Duncan, John, Sujit, Barrett, Robert, McGrath, John, Loa, Peter, Thara, Rangaswamy and Mowry, Bryan (2012). Refining clinical phenotypes by contrasting ethnically different populations with schizophrenia from Australia, India and Sarawak. Psychiatry Research, 196 (2-3), 194-200. doi: 10.1016/j.psychres.2011.12.027

Refining clinical phenotypes by contrasting ethnically different populations with schizophrenia from Australia, India and Sarawak

2012

Journal Article

Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity

Weickert, C. S., Tiwari, Y., Schofield, P. R., Mowry, B. J. and Fullerton, J. M. (2012). Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity. Translational Psychiatry, 2 (4) 201225, e104.1-e104.8. doi: 10.1038/tp.2012.25

Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity

2012

Journal Article

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

Keller, Matthew C., Simonson, Matthew A., Ripke, Stephan, Neale, Ben M., Gejman, Pablo V., Howrigan, Daniel P., Lee, Sang Hong, Lencz, Todd, Levinson, Douglas F., Sullivan, Patrick F., The Schizophrenia Psychiatric Genome-Wide Association Study Consortium and Mowry, Bryan (2012). Runs of homozygosity implicate autozygosity as a schizophrenia risk factor. PloS Genetics, 8 (4) e1002656, 425-435. doi: 10.1371/journal.pgen.1002656

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

2012

Journal Article

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

Lee, S. Hong, DeCandia, Teresa R., Ripke, Stephan, Yang, Jian, Sullivan, Patrick F ., Goddard, Michael E ., Keller, Matthew C ., Visscher, Peter M ., Wray, Naomi R., Schizophrenia Psychiat Genome-Wide, Int Schizophrenia Consortium ISC, Mol Genetics Schizophrenia and Mowry, Bryan (2012). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nature Genetics, 44 (3), 247-250. doi: 10.1038/ng.1108

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

2012

Journal Article

Significant relationship between lifetime alcohol use disorders and suicide attempts in an Australian schizophrenia sample

McLean, Duncan, Gladman, Beverley and Mowry, Bryan (2012). Significant relationship between lifetime alcohol use disorders and suicide attempts in an Australian schizophrenia sample. Australian and New Zealand Journal of Psychiatry, 46 (2), 132-140. doi: 10.1177/0004867411433211

Significant relationship between lifetime alcohol use disorders and suicide attempts in an Australian schizophrenia sample

2012

Journal Article

Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain

Richards, A. L., Jones, L., Moskvina, V., Kirov, G., Gejman, P. V., Levinson, D. F., Sanders, A. R., Molecular Genetics of Schizophrenia Collaboration, International Schizophrenia Consortium (ISC), Purcell, S., Visscher, P. M., Craddock, N., Owen, M. J., O'Donovan, M. C., Holmans, P. and Mowry, B.J. (2012). Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Molecular Psychiatry, 17 (2), 193-201. doi: 10.1038/mp.2011.11

Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain

2012

Journal Article

Don't give up on GWAS

Sullivan, P., on behalf of 96 Psychiatric Genetics Investigators, McGrath, John J., Mowry, Bryan and Wray, Naomi (2012). Don't give up on GWAS. Molecular Psychiatry, 17 (1), 2-3. doi: 10.1038/mp.2011.94

Don't give up on GWAS

2012

Conference Publication

It development and management of a live e-research system: Experiences with the Australian Schizophrenia Research Bank

Paul, D., Henskens, F. A., Loughland, C. M., Bridge, J., McCabe, K., Carr, V. J., Catts, S. V., Jablensky, A., Michie, P. T., Mowry, B. J., Pantelis, C., Schall, U. and Scott, R. J. (2012). It development and management of a live e-research system: Experiences with the Australian Schizophrenia Research Bank. HEALTHINF 2012 - International Conference on Health Informatics, Vilamoura, Algarve, 1 - 4 February 2012. Setubal, Portugal: INSTICC Press.

It development and management of a live e-research system: Experiences with the Australian Schizophrenia Research Bank

2011

Journal Article

Genome-wide association study identifies five new schizophrenia loci

Ripke, Stephan, Sanders, Alan R., Kedler, Kenneth S., Levinson, Douglas F., Sklar, Pamela, Holmans, Peter A., Lin, Dan-Yu, Duan, Jubao, Ophoff, Roel A., Andreassen, Ole A., Scolnick, Edward, Cichon, Sven, St. Clair, David, Corvin, Aiden, Gurling, Hugh, Werge, Thomas, Rujescu, Dan, Blackwood, Douglas H. R., Pato, Carlos N., Malhotra, Anil K., Purcell, Shaun, Dudbridge, Frank, Neale, Benjamin M., Rossin, Lizzy, Visscher, Peter M., Posthuma, Danielle, Ruderfer, Douglas M., Fanous, Ayman, Hreinn, Stefansson ... Gejman, Pablo V. (2011). Genome-wide association study identifies five new schizophrenia loci. Nature Genetics, 43 (10), 969-976. doi: 10.1038/ng.940

Genome-wide association study identifies five new schizophrenia loci

2011

Journal Article

Reliability and validity of a measure of role functioning among people with psychiatric disabilities

Harris, Meredith, Gladman, Beverley, Hennessy, Nicole, Lloyd, Chris, Mowry, Bryan and Waghorn, Geoffrey (2011). Reliability and validity of a measure of role functioning among people with psychiatric disabilities. Australian Occupational Therapy Journal, 58 (3), 203-208. doi: 10.1111/j.1440-1630.2010.00921.x

Reliability and validity of a measure of role functioning among people with psychiatric disabilities

2011

Journal Article

The reliability of an education-related self-efficacy scale for people with psychiatric disabilities

Harris, Meredith, Gladman, Beverley, Hennessy, Nicole, Lloyd, Chris, Mowry, Bryan and Waghorn, Geoffrey (2011). The reliability of an education-related self-efficacy scale for people with psychiatric disabilities. Community Mental Health Journal, 47 (2), 136-142. doi: 10.1007/s10597-010-9294-4

The reliability of an education-related self-efficacy scale for people with psychiatric disabilities

2011

Journal Article

Reliability and validity of a measure of work-related subjective experiences among people with psychiatric disabilities

Waghorn, Geoffrey, Harris, Meredith G., Gladman, Beverly, Hennesey, Nicole, Lloyd, Chris and Mowry, Bryan (2011). Reliability and validity of a measure of work-related subjective experiences among people with psychiatric disabilities. International Journal of Therapy and Rehabilitation, 18 (3), 146-157. doi: 10.12968/ijtr.2011.18.3.146

Reliability and validity of a measure of work-related subjective experiences among people with psychiatric disabilities

Past funding

  • 2022 - 2023
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish (NHMRC Project Grant administered by Griffith University)
    Griffith University
    Open grant
  • 2022
    Genotype Imputation Resources for Productive Genetic Disease Studies of Indigenous Oceanic Sub-Populations
    NHMRC IDEAS Grants
    Open grant
  • 2019 - 2022
    Investigating the neuro-developmental role of schizophrenia-associated genes using the zebrafish.
    NHMRC Project Grant
    Open grant
  • 2016 - 2021
    Investigating the aetiopathogenic role of autoantibodies against the M1 muscarinic acetylcholine receptor in patients with first episode of schizophrenia
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Using the Zebrafish to fight psychiatric disorders. From proof-of-principle to new insights and treatments
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2014 - 2016
    Dissecting the role of RYK in cortical neuron specification and schizophrenia
    NHMRC Project Grant
    Open grant
  • 2014 - 2018
    Genetic analysis of de novo and inherited exome variation in schizophrenia
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Statistical analyses of whole genome genotype data to better understand psychiatric disorders
    NHMRC Project Grant
    Open grant
  • 2012 - 2024
    Genetics of Schizophrenia Research Collaboration Programme
    West Moreton Hospital and Health Service
    Open grant
  • 2012
    Genetics of Schizophrenia Research Collaboration Programme
    Queensland Health
    Open grant
  • 2011
    An automated liquid handling platform for High-throughput Preparation of multiplexed targeted sequence capture DNA libraries for Next-Generation DNA Sequencing (NGS)
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2012
    Establishing a UWA-UQ network for collaboration in Autism Research
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2010
    High performance computing cluster to expand research capacity in neuroscience modelling, imaging and bioinformatics
    NHMRC Equipment Grant
    Open grant
  • 2010 - 2013
    Identifying eQTLs and endophenotyping known CNVs in a large Australian schizophrenia sample
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Linkage and association studies of schizophrenia in an isolated population
    NHMRC Project Grant
    Open grant
  • 2010
    Next-generation DNA sequencer to accelerate discovery in molecular and cellular research programs at QBI
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2014
    Studying the molecular basis of schizophrenia in a large, globally competitive Indian sample
    NHMRC Project Grant
    Open grant
  • 2009 - 2012
    QCMHR Operational (Genetics Laboratory Programme Funding)
    Queensland Health
    Open grant
  • 2006 - 2008
    Adiponectin - Multimerization, Secretion and Action
    NHMRC Project Grant
    Open grant
  • 2006
    Genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 2003 - 2006
    Structural And Diffusion Tensor Neuroimaging In Twins Concordant And Discordant For Psychosis
    NHMRC Project Grant
    Open grant
  • 2002 - 2003
    Australian Psychotic Twins Study - MRI Research
    Schizophrenia Fellowship of South Qld Inc
    Open grant
  • 2000 - 2001
    A genetic study of schizophrenia in regional Tasmania: Initial genotyping of the first large pedigree
    Ramaciotti Foundation
    Open grant
  • 2000
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant
  • 1999 - 2003
    Molecular genetics of Schizophrenia
    United States National Institutes of Health
    Open grant
  • 1999 - 2001
    A Genetic Study of Schizophrenia in the Iban of Sarawak
    NHMRC Project Grant
    Open grant
  • 1999
    The molecular genetics of schizophrenia (2)
    Garvan Institute
    Open grant
  • 1998 - 2012
    QCMHR Operational (Genetics Research Project)
    Queensland Health
    Open grant
  • 1998 - 2006
    An integrated research program examining risk factors for psychoses
    Stanley Foundation Research Awards Program
    Open grant
  • 1997 - 1999
    A genetic study of schizophrenia in Fiji
    Scottish Rite Schizophrenia Research Program
    Open grant
  • 1997
    A molecular genetic linkage study of Schizophrenia
    UQ Foundation
    Open grant
  • 1997 - 1999
    A molecular genetic linkage study of schizophrenia
    NHMRC Project Grant
    Open grant
  • 1997
    A molecular genetic linkage study of schizophrenia
    Ramaciotti Foundation
    Open grant
  • 1996 - 1997
    Molecular genetic linkage study of schizophrenia
    Perpetual Trustee Company Limited
    Open grant
  • 1996 - 1997
    Schizophrenia Genetics Research Program : Hot spot mapping in an extended schizophrenia cohort
    Queensland Health
    Open grant
  • 1996 - 1997
    The molecular genetics of schizophrenia
    RL Cooper Medical Research Foundation Limited
    Open grant

Availability

Professor Bryan Mowry is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

Contact Professor Bryan Mowry directly for media enquiries about:

  • Culture and psychiatry
  • Ethics - psychiatry
  • Genetics and mental illnesses
  • Health - mental
  • Mental illness and genetics
  • Psychiatric ethics
  • Psychiatry - trans-cultural
  • Schizophrenia
  • Trans-cultural psychiatry

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