
Overview
Background
Bryan is a graduate in medicine from the University of Queensland and holds a BA (Hons) degree in philosophy from the University of Western Australia. A medical specialist in psychiatry, he is a clinician researcher, who is Conjoint Professor at the Queensland Brain Institute, University of Queensland, and Director of Genetics at the Queensland Centre for Mental Health Research. His primary research interest is the molecular genetics of schizophrenia, and holds a MD degree (University of Queensland) in this field. Since 1990, he has conducted studies, with national and international collaborators, to identify susceptibility genes for this disorder. He is the recipient of grants from the Australian NHMRC and the US NIMH.
The primary research goal is to identify and functionally characterise susceptibility genes for schizophrenia and related disorders. A special focus is on the study of large collaborative samples and ethnically homogeneous populations. Key methodologies used in the lab include genome-wide association studies, next-generation sequencing, transcriptome profiling of post-mortem brain samples, neurocognitive and neuroimaging phenotyping and induced pluripotent stem cells.
Current areas of interest include pharmacogenomics of clozapine treatment response, whole exome sequencing focused on de novo mutations, and the neuroimmunology of schizophrenia
Availability
- Professor Bryan Mowry is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Royal Australian and New Zealand College of Psychiatrists, Royal Australian and New Zealand College of Psychiatrists
Works
Search Professor Bryan Mowry’s works on UQ eSpace
2021
Journal Article
Pipeline for generating stable large genomic deletions in zebrafish, from small domains to whole gene excisions
Tromp, Alisha, Robinson, Kate, Hall, Thomas E., Mowry, Bryan and Giacomotto, Jean (2021). Pipeline for generating stable large genomic deletions in zebrafish, from small domains to whole gene excisions. G3 Genes|Genomes|Genetics, 11 (12) jkab321. doi: 10.1093/g3journal/jkab321
2021
Journal Article
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Mullins, Niamh, Forstner, Andreas J., O'Connell, Kevin S., Coombes, Brandon, Coleman, Jonathan R I, Qiao, Zhen, Als, Thomas D., Bigdeli, Tim B., Børte, Sigrid, Bryois, Julien, Charney, Alexander W., Drange, Ole Kristian, Gandal, Michael J., Hagenaars, Saskia P., Ikeda, Masashi, Kamitaki, Nolan, Kim, Minsoo, Krebs, Kristi, Panagiotaropoulou, Georgia, Schilder, Brian M., Sloofman, Laura G., Steinberg, Stacy, Trubetskoy, Vassily, Winsvold, Bendik S., Won, Hong-Hee, Abramova, Liliya, Adorjan, Kristina, Agerbo, Esben, Al Eissa, Mariam ... Andreassen, Ole A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature genetics, 53 (6), 817-829. doi: 10.1038/s41588-021-00857-4
2021
Journal Article
Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium
Peterson, Roseann E., Bigdeli, Tim B., Ripke, Stephan, Bacanu, Silviu-Alin, Gejman, Pablo V., Levinson, Douglas F., Li, Qingqin S., Rujescu, Dan, Rietschel, Marcella, Weinberger, Daniel R., Straub, Richard E., Walters, James T.R., Owen, Michael J., O'Donovan, Michael C., Mowry, Bryan J., Ophoff, Roel A., Andreassen, Ole A., Esko, Tõnu, Petryshen, Tracey L., Kendler, Kenneth S. and Fanous, Ayman H. (2021). Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium. Journal of Psychiatric Research, 137, 215-224. doi: 10.1016/j.jpsychires.2021.02.027
2020
Journal Article
Neurexins in autism and schizophrenia-a review of patient mutations, mouse models and potential future directions
Tromp, Alisha, Mowry, Bryan and Giacomotto, Jean (2020). Neurexins in autism and schizophrenia-a review of patient mutations, mouse models and potential future directions. Molecular Psychiatry, 26 (3), 747-760. doi: 10.1038/s41380-020-00944-8
2020
Journal Article
Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA
Radua, Joaquim, Vieta, Eduard, Shinohara, Russell, Kochunov, Peter, Quidé, Yann, Green, Melissa J., Weickert, Cynthia S., Weickert, Thomas, Bruggemann, Jason, Kircher, Tilo, Nenadić, Igor, Cairns, Murray J., Seal, Marc, Schall, Ulrich, Henskens, Frans, Fullerton, Janice M., Mowry, Bryan, Pantelis, Christos, Lenroot, Rhoshel, Cropley, Vanessa, Loughland, Carmel, Scott, Rodney, Wolf, Daniel, Satterthwaite, Theodore D., Tan, Yunlong, Sim, Kang, Piras, Fabrizio, Spalletta, Gianfranco, Banaj, Nerisa ... ENIGMA Consortium collaborators (2020). Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA. NeuroImage, 218 116956, 1-14. doi: 10.1016/j.neuroimage.2020.116956
2020
Journal Article
The genetic architecture of the human cerebral cortex
Grasby, Katrina L., Jahanshad, Neda, Painter, Jodie N., Colodro-Conde, Lucía, Bralten, Janita, Hibar, Derrek P., Lind, Penelope A., Pizzagalli, Fabrizio, Ching, Christopher R. K., McMahon, Mary Agnes B., Shatokhina, Natalia, Zsembik, Leo C. P., Thomopoulos, Sophia I., Zhu, Alyssa H., Strike, Lachlan T., Agartz, Ingrid, Alhusaini, Saud, Almeida, Marcio A. A., Alnæs, Dag, Amlien, Inge K., Andersson, Micael, Ard, Tyler, Armstrong, Nicola J., Ashley-Koch, Allison, Atkins, Joshua R., Bernard, Manon, Brouwer, Rachel M., Buimer, Elizabeth E. L., Bülow, Robin ... Medland, Sarah E. (2020). The genetic architecture of the human cerebral cortex. Science, 367 (6484) aay6690, 1-17. doi: 10.1126/science.aay6690
2020
Journal Article
Complement genes contribute sex-biased vulnerability in diverse disorders
Kamitaki, Nolan, Sekar, Aswin, Handsaker, Robert E., de Rivera, Heather, Tooley, Katherine, Morris, David L., Taylor, Kimberly E., Whelan, Christopher W., Tombleson, Philip, Loohuis, Loes M. Olde, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T. R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Begemann, Martin, Belliveau, Richard A. ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (2020). Complement genes contribute sex-biased vulnerability in diverse disorders. Nature, 582 (7813), 577-581+. doi: 10.1038/s41586-020-2277-x
2020
Journal Article
Association of HLA-A, -B, -C, -DRB1 and -DQB1 alleles at amino acid level in individuals with schizophrenia: A study from South India
Seshasubramanian, Vani, Raghavan, Vijaya, Sathish Kannan, Aruna Devi, Naganathan, Chandramouleeswaran, Ramachandran, Aparna, Arasu, Priya, Rajendren, Preeti, John, Sujit, Mowry, Brian, Rangaswamy, Thara, Narayan, Saranya and Periathiruvadi, Srinivasan (2020). Association of HLA-A, -B, -C, -DRB1 and -DQB1 alleles at amino acid level in individuals with schizophrenia: A study from South India. International Journal of Immunogenetics, 47 (6) iji.12507, 501-511. doi: 10.1111/iji.12507
2019
Journal Article
Cover image
Dzafic, Ilvana, Oestreich, Lena, Martin, Andrew K., Mowry, Bryan and Burianová, Hana (2019). Cover image. Human Brain Mapping, 40 (18). doi: 10.1002/hbm.24301
2019
Journal Article
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
Lee, Phil H., Anttila, Verneri, Won, Hyejung, Feng, Yen-Chen A., Rosenthal, Jacob, Zhu, Zhaozhong, Tucker-Drob, Elliot M., Nivard, Michel G., Grotzinger, Andrew D., Posthuma, Danielle, Wang, Meg M.-J., Yu, Dongmei, Stahl, Eli A., Walters, Raymond K., Anney, Richard J.L., Duncan, Laramie E., Ge, Tian, Adolfsson, Rolf, Banaschewski, Tobias, Belangero, Sintia, Cook, Edwin H., Coppola, Giovanni, Derks, Eske M., Hoekstra, Pieter J., Kaprio, Jaakko, Keski-Rahkonen, Anna, Kirov, George, Kranzler, Henry R., Luykx, Jurjen J. ... Smoller, Jordan W. (2019). Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders. Cell, 179 (7), 1469-1482.e11. doi: 10.1016/j.cell.2019.11.020
2019
Journal Article
Comparative genetic architectures of schizophrenia in East Asian and European populations
Lam, Max, Chen, Chia-Yen, Li, Zhiqiang, Martin, Alicia R., Bryois, Julien, Ma, Xixian, Gaspar, Helena, Ikeda, Masashi, Benyamin, Beben, Brown, Brielin C., Liu, Ruize, Zhou, Wei, Guan, Lili, Kamatani, Yoichiro, Kim, Sung-Wan, Kubo, Michiaki, Kusumawardhani, Agung A. A. A., Liu, Chih-Min, Ma, Hong, Periyasamy, Sathish, Takahashi, Atsushi, Xu, Zhida, Yu, Hao, Zhu, Feng, Chen, Wei J., Faraone, Stephen, Glatt, Stephen J., He, Lin, Hyman, Steven E. ... Huang, Hailiang (2019). Comparative genetic architectures of schizophrenia in East Asian and European populations. Nature Genetics, 51 (12), 1670-1678. doi: 10.1038/s41588-019-0512-x
2019
Journal Article
Wnt receptor gene FZD1 was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort
Liu, Xiaoman, Low, Siew-Kee, Atkins, Joshua R., Wu, Jing Qin, Reay, William R., Cairns, Heath M., Green, Melissa J., Schall, Ulrich, Jablensky, Assen, Mowry, Bryan, Michie, Patricia T., Catts, Stan V., Henskens, Frans, Pantelis, Christos, Loughland, Carmel, Boddy, Alan V., Tooney, Paul A., Scott, Rodney J., Carr, Vaughan J. and Cairns, Murray J. (2019). Wnt receptor gene FZD1 was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort. Australian and New Zealand Journal of Psychiatry, 54 (9) 0004867419885443, 000486741988544-908. doi: 10.1177/0004867419885443
2019
Conference Publication
A novel approach for the generation of disease-specific genetic interaction data using gene-based statistical epistasis
Periyasamy, Sathish and Mowry, Bryan (2019). A novel approach for the generation of disease-specific genetic interaction data using gene-based statistical epistasis. International Conference on Systems Biology, Okinawa, Japan, 1-5 November 2019. Okinawa:
2019
Journal Article
SummaryAUC: a tool for evaluating the performance of polygenic risk prediction models in validation datasets with only summary level statistics
Song, Lei, Liu, Aiyi, Molecular Genetics of Schizophrenia Consortium, Shi, Jianxin, Gejman, P. V., Sanders, A. R., Duan, J., Cloninger, C. R., Svrakic, D. M., Buccola, N. G., Levinson, D. F., Mowry, B. J., Freedman, R., Olincy, A., Amin, F., Black, D. W., Silverman, J. M. and Byerley, W. F. (2019). SummaryAUC: a tool for evaluating the performance of polygenic risk prediction models in validation datasets with only summary level statistics. Bioinformatics, 35 (20), 4038-4044. doi: 10.1093/bioinformatics/btz176
2019
Conference Publication
Prioritising causal variants in schizophrenia GWAS by investigating the regulatory impact of non-coding variants using differential binding and brain EQTL data
Mowry, Bryan and Periyasamy, Sathish (2019). Prioritising causal variants in schizophrenia GWAS by investigating the regulatory impact of non-coding variants using differential binding and brain EQTL data. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, CA USA, 26-31 October 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.08.288
2019
Journal Article
Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations
Peterson, Roseann E., Kuchenbaecker, Karoline, Walters, Raymond K., Chen, Chia-Yen, Popejoy, Alice B., Periyasamy, Sathish, Lam, Max, Iyegbe, Conrad, Strawbridge, Rona J., Brick, Leslie, Carey, Caitlin E., Martin, Alicia R., Meyers, Jacquelyn L., Su, Jinni, Chen, Junfang, Edwards, Alexis C., Kalungi, Allan, Koen, Nastassja, Majara, Lerato, Schwarz, Emanuel, Smoller, Jordan W., Stahl, Eli A., Sullivan, Patrick F., Vassos, Evangelos, Mowry, Bryan, Prieto, Miguel L., Cuellar-Barboza, Alfredo, Bigdeli, Tim B., Edenberg, Howard J. ... Duncan, Laramie E. (2019). Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations. Cell, 179 (3), 589-603. doi: 10.1016/j.cell.2019.08.051
2019
Journal Article
Stria terminalis, amygdala, and temporoparietal junction networks facilitate efficient emotion processing under expectations
Dzafic, Ilvana, Oestreich, Lena, Martin, Andrew K., Mowry, Bryan and Burianová, Hana (2019). Stria terminalis, amygdala, and temporoparietal junction networks facilitate efficient emotion processing under expectations. Human Brain Mapping, 40 (18) hbm.24779, 5382-5396. doi: 10.1002/hbm.24779
2019
Journal Article
Is there a role for antibodies targeting muscarinic acetylcholine receptors in the pathogenesis of schizophrenia?
Ryan, Alexander E., Mowry, Bryan J., Kesby, James P., Scott, James G. and Greer, Judith M. (2019). Is there a role for antibodies targeting muscarinic acetylcholine receptors in the pathogenesis of schizophrenia?. Australian and New Zealand Journal of Psychiatry, 53 (11) 0004867419864438, 1-11. doi: 10.1177/0004867419864438
2019
Journal Article
Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study
Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Vinkhuyzen, Anna, McRae, Allan, Holliday, Elizabeth G., Nyholt, Dale R., Nancarrow, Derek, Bakshi, Andrew, Hemani, Gibran, Nertney, Deborah, Smith, Heather, Filippich, Cheryl, Patel, Kalpana, Fowdar, Javed, McLean, Duncan, Tirupati, Srinivasan, Nagasundaram, Arunkumar, Gundugurti, Prasad Rao, Selvaraj, Krishnamurthy, Jegadeesan, Jayaprakash, Jorde, Lynn B., Wray, Naomi R., Brown, Matthew A., Suetani, Rachel, Giacomotto, Jean ... Mowry, Bryan J. (2019). Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study. JAMA Psychiatry, 76 (10), 1026-1034. doi: 10.1001/jamapsychiatry.2019.1335
2019
Journal Article
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (Nature Genetics, (2019), 51, 4, (659-674), 10.1038/s41588-019-0364-4)
Huckins, Laura M., Dobbyn, Amanda, Ruderfer, Douglas M., Hoffman, Gabriel, Wang, Weiqing, Pardiñas, Antonio F., Rajagopal, Veera M., Als, Thomas D., T. Nguyen, Hoang, Girdhar, Kiran, Boocock, James, Roussos, Panos, Fromer, Menachem, Kramer, Robin, Domenici, Enrico, Gamazon, Eric R., Purcell, Shaun, Johnson, Jessica S., Shah, Hardik R., Klein, Lambertus L., Dang, Kristen K., Logsdon, Benjamin A., Mahajan, Milind C., Mangravite, Lara M., Toyoshiba, Hiroyoshi, Gur, Raquel E., Hahn, Chang-Gyu, Schadt, Eric, Lewis, David A. ... Stahl, Eli A. (2019). Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (Nature Genetics, (2019), 51, 4, (659-674), 10.1038/s41588-019-0364-4). Nature Genetics, 51 (6), 1068-1068. doi: 10.1038/s41588-019-0435-6
Funding
Past funding
Supervision
Availability
- Professor Bryan Mowry is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Completed supervision
-
2021
Doctor Philosophy
New technologies and models to investigate the functional role of neurexins in zebrafish
Principal Advisor
Other advisors: Dr Jean Giacomotto
-
2017
Doctor Philosophy
The Neuroimaging and Genetics of Emotion Perception in Schizophrenia
Principal Advisor
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2016
Doctor Philosophy
Contrasting the Expression of Psychotic Disorders in Ethnically Different Populations
Principal Advisor
Other advisors: Professor John McGrath
-
2015
Doctor Philosophy
Characterizing copy number variants in schizophrenia: a clinical, neuropsychological, and neuroimaging study.
Principal Advisor
Other advisors: Professor Gail Robinson
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2015
Doctor Philosophy
Analysis of non-coding RNA expression in schizophrenia brain
Principal Advisor
Other advisors: Honorary Professor Jake Gratten
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2002
Doctor Philosophy
MOLECULAR CANDIDATES FOR SCHIZOPHRENIA
Principal Advisor
Other advisors: Professor John McGrath
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2012
Doctor Philosophy
Immune dysregulation in schizophrenia: Do some cases of schizophrenia have an autoimmune basis?
Associate Advisor
Other advisors: Emeritus Professor Michael Pender, Associate Professor Judith Greer
Media
Enquiries
Contact Professor Bryan Mowry directly for media enquiries about:
- Culture and psychiatry
- Ethics - psychiatry
- Genetics and mental illnesses
- Health - mental
- Mental illness and genetics
- Psychiatric ethics
- Psychiatry - trans-cultural
- Schizophrenia
- Trans-cultural psychiatry
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