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2018 Journal Article Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1de Veer, Simon J., Li, Choi Yi, Swedberg, Joakim E., Schroeder, Christina I. and Craik, David J. (2018). Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1. European Journal of Medicinal Chemistry, 155, 695-704. doi: 10.1016/j.ejmech.2018.06.029 |
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2018 Journal Article Defense peptides engineered from human platelet factor 4 kill Plasmodium by selective membrane disruptionLawrence, Nicole, Dennis, Adelaide S. M., Lehane, Adele M., Ehmann, Anna, Harvey, Peta J., Benfield, Aurélie H., Cheneval, Olivier, Henriques, Sónia Troeira, Craik, David J. and McMorran, Brendan J. (2018). Defense peptides engineered from human platelet factor 4 kill Plasmodium by selective membrane disruption. Cell Chemical Biology, 25 (9), 1140-+. doi: 10.1016/j.chembiol.2018.06.009 |
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2018 Journal Article Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidasesJackson, M. A., Gilding, E. K., Shafee, T., Harris, K. S., Kaas, Q., Poon, S., Yap, K., Jia, H., Guarino, R., Chan, L. Y., Durek, T., Anderson, M. A. and Craik, D. J. (2018). Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases. Nature Communications, 9 (1) 2411, 2411. doi: 10.1038/s41467-018-04669-9 |
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2018 Journal Article Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1Sadeghi, Mahsa, Carstens, Bodil B., Callaghan, Brid P., Daniel, James T., Tae, Han Shen, O'Donnell, Tracey, Castro, Joel, Brierley, Stuart M., Adams, David J., Craik, David J. and Clark, Richard J. (2018). Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. ACS Chemical Biology, 13 (6), 1577-1587. doi: 10.1021/acschembio.8b00190 |
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2018 Journal Article Calcium-mediated allostery of the EGF foldWang, Conan K., Ghani, Hafiza Abdul, Bundock, Anna, Weidmann, Joachim, Harvey, Peta J., Edwards, Ingrid A., Schroeder, Christina I., Swedberg, Joakim E. and Craik, David J. (2018). Calcium-mediated allostery of the EGF fold. ACS Chemical Biology, 13 (6), 1659-1667. doi: 10.1021/acschembio.8b00291 |
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2018 Journal Article Emerging peptide science in AustraliaCraik, David J. and Payne, Richard J. (2018). Emerging peptide science in Australia. Peptide Science, 110 (3) e24080, e24080. doi: 10.1002/pep2.24080 |
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2018 Journal Article Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranesAgwa, Akello J., Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David J., Tytgat, Jan, King, Glenn F., Henriques, Sonia Troeira and Schroeder, Christina I. (2018). Gating modifier toxins isolated from spider venom: modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293 (23), 9041-9052. doi: 10.1074/jbc.RA118.002553 |
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2018 Journal Article Designing macrocyclic disulfide-rich peptides for biotechnological applicationsWang, Conan K. and Craik, David J. (2018). Designing macrocyclic disulfide-rich peptides for biotechnological applications. Nature Chemical Biology, 14 (5), 417-427. doi: 10.1038/s41589-018-0039-y |
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2018 Journal Article Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1Durek, Thomas, Cromm, Philipp M., White, Andrew M., Schroeder, Christina I., Kaas, Quentin, Weidmann, Joachim, Ahmad Fuaad, Abdullah, Cheneval, Olivier, Harvey, Peta J., Daly, Norelle L., Zhou, Yang, Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Kessler, Horst, Cai, Minying, Hruby, Victor J., Plowright, Alleyn T. and Craik, David J. (2018). Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1. Journal of Medicinal Chemistry, 61 (8), 3674-3684. doi: 10.1021/acs.jmedchem.8b00170 |
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2018 Journal Article Bioactive compounds isolated from neglected predatory marine gastropodsTurner, Ashlin H., Craik, David J., Kaas, Quentin and Schroeder, Christina I. (2018). Bioactive compounds isolated from neglected predatory marine gastropods. Marine Drugs, 16 (4) 118, 118. doi: 10.3390/md16040118 |
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2018 Journal Article Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal painCastro, Joel, Grundy, Luke, Deiteren, Annemie, Harrington, Andrea M., O'Donnell, Tracey, Maddern, Jessica, Moore, Jessi, Garcia-Caraballo, Sonia, Rychkov, Grigori Y., Yu, Rilei, Kaas, Quentin, Craik, David J., Adams, David J. and Brierley, Stuart M. (2018). Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain. British Journal of Pharmacology, 175 (12), 2384-2398. doi: 10.1111/bph.14115 |
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2018 Journal Article Conformational Flexibility Is a Determinant of Permeability for CyclosporinWang, Conan K., Swedberg, Joakim E., Harvey, Peta J., Kaas, Quentin and Craik, David J. (2018). Conformational Flexibility Is a Determinant of Permeability for Cyclosporin. The Journal of Physical Chemistry. B, 122 (8), 2261-2276. doi: 10.1021/acs.jpcb.7b12419 |
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2018 Journal Article The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6Israel, Mathilde R., Thongyoo, Panumart, Deuis, Jennifer R., Craik, David J., Vetter, Irina and Durek, Thomas (2018). The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human NaV1.6. Journal of Medicinal Chemistry, 61 (4), 1730-1736. doi: 10.1021/acs.jmedchem.7b01609 |
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2017 Journal Article Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in plantaPoon, Simon, Harris, Karen S, Jackson, Mark A, McCorkelle, Owen C, Gilding, Edward K, Durek, Thomas, van der Weerden, Nicole L, Craik, David J and Anderson, Marilyn A (2017). Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta. Journal of experimental botany, 69 (3), 633-641. doi: 10.1093/jxb/erx422 |
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2017 Journal Article Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine ReceptorsDurek, Thomas, Shelukhina, Irina V., Tae, Han-Shen, Thongyoo, Panumart, Spirova, Ekaterina N., Kudryavtsev, Denis S., Kasheverov, Igor E., Faure, Grazyna, Corringer, Pierre-Jean, Craik, David J., Adams, David J. and Tsetlin, Victor I. (2017). Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Scientific Reports, 7 (1) 16606, 16606. doi: 10.1038/s41598-017-16809-0 |
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2017 Journal Article Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017)Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sonia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa(V)1.7 (vol 1859, pg 835, 2017). Biochimica Et Biophysica Acta-Biomembranes, 1859 (11), 2277-2277. doi: 10.1016/j.bbamem.2017.08.008 |
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2017 Journal Article Redesigned spider peptide with improved antimicrobial and anticancer propertiesHenriques, Sónia Troeira, Lawrence, Nicole, Chaousis, Stephanie, Ravipati, Anjaneya S., Cheneval, Olivier, Benfield, Aurélie H., Elliott, Alysha G., Kavanagh, Angela Maria, Cooper, Matthew A., Chan, Lai Yue, Huang, Yen-Hua and Craik, David J. (2017). Redesigned spider peptide with improved antimicrobial and anticancer properties. ACS Chemical Biology, 12 (9), 2324-2334. doi: 10.1021/acschembio.7b00459 |
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2017 Journal Article Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptakeOjeda, Paola G. , Henriques, Sonia Troeira, Pan, Yijun, Nicolazzo, Joseph A., Craik, David J. and Wang, Conan K. (2017). Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake. Biopolymers, 108 (5) e23025, e23025. doi: 10.1002/bip.23025 |
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2017 Journal Article Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomerWu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin, Harvey, Peta J., Wang, Conan K., Tae, Han-Shen, Adams, David J. and Craik, David J. (2017). Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. Journal of Biological Chemistry, 292 (41), 17101-17112. doi: 10.1074/jbc.M117.808386 |
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2017 Journal Article Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxinsAgwa, Akello J., Huang, Yen-Hua, Craik, David J., Henriques, Sonia T. and Schroeder, Christina I. (2017). Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxins. Toxins, 9 (8) 248, 248. doi: 10.3390/toxins9080248 |
