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2017 Journal Article Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxinsAgwa, Akello J., Huang, Yen-Hua, Craik, David J., Henriques, Sonia T. and Schroeder, Christina I. (2017). Lengths of the C-terminus and interconnecting loops impact stability of spider-derived gating modifier toxins. Toxins, 9 (8) 248, 248. doi: 10.3390/toxins9080248 |
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2017 Journal Article Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffoldsCraik, David J., Lee, Meng-Han, Rehm, Fabian B.H., Tombling, Benjamin, Doffek, Benjamin and Peacock, Hayden (2017). Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds. Bioorganic and Medicinal Chemistry, 26 (10), 2727-2737. doi: 10.1016/j.bmc.2017.08.005 |
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2017 Journal Article α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine ReceptorsWu, Yong, Zhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Zhangsun, Manqi, Harvey, Peta J., Craik, David J., McIntosh, J. Michael and Luo, Sulan (2017). α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry, 60 (13), 5826-5833. doi: 10.1021/acs.jmedchem.7b00546 |
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2017 Journal Article Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranesCranfield, Charles G., Henriques, Sonia Troeira, Martinac, Boris, Duckworth, Paul, Craik, David J. and Cornell, Bruce (2017). Kalata B1 and Kalata B2 have a surfactant-like activity in phosphatidylethanolomine-containing lipid membranes. Langmuir, 33 (26), 6630-6637. doi: 10.1021/acs.langmuir.7b01642 |
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2017 Journal Article Cyclotides as tools in chemical biologyde Veer, Simon J., Weidmann, Joachim and Craik, David J. (2017). Cyclotides as tools in chemical biology. Accounts of Chemical Research, 50 (7), 1557-1565. doi: 10.1021/acs.accounts.7b00157 |
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2017 Journal Article Cyclotides as drug design scaffoldsCraik, David J. and Du, Junqiao (2017). Cyclotides as drug design scaffolds. Current Opinion in Chemical Biology, 38, 8-16. doi: 10.1016/j.cbpa.2017.01.018 |
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2017 Journal Article Editorial overviewCraik, David J. and Henriques, Sonia Troeira (2017). Editorial overview. Current Opinion in Chemical Biology, 38, iv-vi. doi: 10.1016/j.cbpa.2017.05.012 |
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2017 Journal Article Understanding the diversity and distribution of cyclotides from plants of varied genetic originRavipati, Anjaneya S., Poth, Aaron G., Henriques, Sonia Troeira, Bhandari, Murari, Huang, Yen-Hua, Nino, Jaime, Colgrave, Michelle L. and Craik, David J. (2017). Understanding the diversity and distribution of cyclotides from plants of varied genetic origin. Journal of Natural Products, 80 (5), 1522-1530. doi: 10.1021/acs.jnatprod.7b00061 |
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2017 Journal Article Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7Agwa, Akello J., Lawrence, Nicole, Deplazes, Evelyne, Cheneval, Olivier, Chen, Rachel M., Craik, David J., Schroeder, Christina I. and Henriques, Sónia T. (2017). Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochimica et Biophysica Acta. Biomembranes, 1859 (5), 835-844. doi: 10.1016/j.bbamem.2017.01.020 |
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2017 Journal Article αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtypeZhangsun, Dongting, Zhu, Xiaopeng, Kaas, Quentin, Wu, Yong, Craik, David J. , McIntosh, J. Michael and Luo, Sulan (2017). αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype. Neuropharmacology, 127, 243-252. doi: 10.1016/j.neuropharm.2017.04.015 |
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2017 Journal Article Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRETKubota, Tomoya, Durek, Thomas, Dang, Bobo, Finol-Urdaneta, Rocio K., Craik, David J., Kent, Stephen B. H., French, Robert J., Bezanilla, Francisco and Correa, Ana M. (2017). Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences, 114 (10), E1857-E1865. doi: 10.1073/pnas.1700453114 |
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2017 Journal Article Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMRGrage, Stephan L., Sani, Marc-Antoine, Cheneval, Olivier, Henriques, Sonia Troeira, Schalck, Constantin, Heinzmann, Ralf, Mylne, Joshua S., Mykhailiuk, Pavel K., Afonin, Sergii, Komarov, Igor V., Separovic, Frances, Craik, David J. and Ulrich, Anne S. (2017). Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMR. Biophysical Journal, 112 (4), 630-642. doi: 10.1016/j.bpj.2016.12.040 |
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2017 Journal Article Cyclotide structure and function: the role of membrane binding and permeationTroeira Henriques, Sonia and Craik, David J. (2017). Cyclotide structure and function: the role of membrane binding and permeation. Biochemistry, 56 (5), 669-682. doi: 10.1021/acs.biochem.6b01212 |
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2017 Journal Article Synthesis and protein engineering applications of cyclotidesQu, Haiou, Smithies, Bronwyn J. , Durek, Thomas and Craik, David J. (2017). Synthesis and protein engineering applications of cyclotides. Australian Journal of Chemistry, 70 (2), 152-161. doi: 10.1071/CH16589 |
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2017 Journal Article Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffoldSwedberg, Joakim E., Li, Choi Yi, De Veer, Simon J., Wang, Conan K. and Craik, David J. (2017). Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold. Journal of Medicinal Chemistry, 60 (2), 658-667. doi: 10.1021/acs.jmedchem.6b01509 |
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2017 Journal Article Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamiliesAbdul Ghani, Hafiza, Henriques, Sonia Troeira, Huang, Yen-Hua, Swedberg, Joakim E. , Schroeder, Christina I. and Craik, David J. (2017). Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies. Biopolymers, 108 (1) e22927, e22927. doi: 10.1002/bip.22927 |
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2017 Journal Article Identification of survival-promoting OSIP108 peptide variants and their internalization in human cellsVerbandt, Sara, Henriques, Sónia Troeira, Spincemaille, Pieter, Harvey, Peta J., Chandhok, Gursimran, Sauer, Vanessa, De Coninck, Barbara, Cassiman, David, Craik, David J., Cammue, Bruno P. A., De Cremer, Kaat and Thevissen, Karin (2017). Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells. Mechanisms of Ageing and Development, 161 (B), 247-254. doi: 10.1016/j.mad.2016.07.013 |
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2016 Journal Article Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloidsMatsuura, Helio N., Poth, Aaron G., Yendo, Anna C. A., Fett-Neto, Arthur G. and Craik, David J. (2016). Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloids. Journal of Natural Products, 79 (12), 3006-3013. doi: 10.1021/acs.jnatprod.6b00492 |
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2016 Journal Article Discovery and optimization of peptide macrocyclesWhite, Andrew M. and Craik, David J. (2016). Discovery and optimization of peptide macrocycles. Expert Opinion on Drug Discovery, 11 (12), 1151-1163. doi: 10.1080/17460441.2016.1245720 |
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2016 Journal Article Characterization of a bioactive acyclotide from Palicourea rigidaPinto, Michelle F. S., Silva, Osmar N., Viana, Juilan C., Porto, William F., Migliolo, Ludovico, da Cunha, Nicolau B., Gomes Jr., Nelson, Fensterseifer, Isabel C. M., Colgrave, Michelle L., Craik, David J., Dias, Simoni C. and Franco, Octavio L. (2016). Characterization of a bioactive acyclotide from Palicourea rigida. Journal of Natural Products, 79 (11), 2767-2773. doi: 10.1021/acs.jnatprod.6b00270 |
