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2015 Journal Article Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffoldHuang, Yen-Hua, Henriques, Sonia T., Wang, Conan K., Thorstholm, Louise, Daly, Norelle L., Kaas, Quentin and Craik, David J. (2015). Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold. Scientific Reports, 5 (1) 12974, 1-15. doi: 10.1038/srep12974 |
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2015 Journal Article Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faeciumHimeno, Kohei, Rosengren, K. Johan, Inoue, Tomoko, Perez, Rodney H., Colgrave, Michelle L., Lee, Han Siean, Chan, Lai Y., Henriques, Sonia Troeira, Fujita, Koji, Ishibashi, Naoki, Zendo, Takeshi, Wilaipun, Pongtep, Nakayama, Jiro, Leelawatcharamas, Vichien, Jikuya, Hiroyuki, Craik, David J. and Sonomoto, Kenji (2015). Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium. Biochemistry, 54 (31), 4863-4876. doi: 10.1021/acs.biochem.5b00196 |
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2015 Journal Article Synergistic activity of the plant defensin HsAFP1 and caspofungin against Candida albicans biofilms and planktonic culturesVriens, Kim, Cools, Tanne L., Harvey, Peta J., Craik, David J., Spincemaille, Pieter, Cassiman, David, Braem, Annabel, Vleugels, Jozef, Nibbering, Peter H., Drijfhout, Jan Wouter, De Coninck, Barbara, Cammue, Bruno P. A. and Thevissen, Karin (2015). Synergistic activity of the plant defensin HsAFP1 and caspofungin against Candida albicans biofilms and planktonic cultures. PLoS ONE, 10 (8) e0132701, 1-22. doi: 10.1371/journal.pone.0132701 |
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2015 Journal Article Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonistLuo, Sulan, Zhangsun, Dongting, Harvey, Peta J., Kaas, Quentin, Wu, Yong, Zhu, Xiaopeng, Hu, Yuanyan, Li, Xiaodan, Tsetlin, Victor. I., Christensen, Sean, Romero, Haylie K., McIntrye, Melissa, Dowell, Cheryl, Baxter, James, C., Elmslie, Keith S., Craik, David J. and McIntosh, Michael (2015). Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 112 (30), e4026-e4035. doi: 10.1073/pnas.1503617112 |
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2015 Journal Article Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibitionde Veer, Simon J., Swedberg, Joakim E., Akcan, Muharrem, Rosengren, K. Johan, Brattsand, Maria, Craik, David J. and Harris, Jonathan M. (2015). Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition. Biochemical Journal, 469 (2), 243-253. doi: 10.1042/BJ20150412 |
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2015 Journal Article Bioinformatics-aided venomicsKaas, Quentin and Craik, David J. (2015). Bioinformatics-aided venomics. Toxins, 7 (6), 2159-2187. doi: 10.3390/toxins7062159 |
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2015 Journal Article Key challenges for the creation and maintenance of specialist protein resourcesHolliday, Gemma L., Bairoch, Amos, Bagos, Pantelis G., Chatonnet, Arnaud, Craik, David J., Flinn, Robert D., Henrissat, Bernard, Landsman, David, Manning, Gerard, Nagano, Nozomi, O'Donovan, Claire, Pruitt, Kim D., Rawlings, Neil D., Saier, Milton, Sowdhamini, Ramanathan, Spedding, Michael, Srinivasan, Narayanaswamy, Vriend, Gert, Babbitt, Patricia C. and Bateman, Alex (2015). Key challenges for the creation and maintenance of specialist protein resources. Proteins: Structure, Function and Bioinformatics, 83 (6), 1005-1013. doi: 10.1002/prot.24803 |
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2015 Journal Article Peptide macrocyclization by a bifunctional endoproteaseBernath-Levin, Kalia, Nelson, Clark, Elliott, Alysha G., Jayasena, Achala S., Millar, A. Harvey, Craik, David J. and Mylne, Joshua S. (2015). Peptide macrocyclization by a bifunctional endoprotease. Chemistry and Biology, 22 (5), 571-582. doi: 10.1016/j.chembiol.2015.04.010 |
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2015 Journal Article Exploring experimental and computational markers of cyclic peptides: charting islands of permeabilityWang, Conan K., Northfield, Susan Ellen, Swedberg, Joakim E., Colless, Barbara, Chaousis, Stephanie, Price, David A., Liras, Spiros and Craik, David J. (2015). Exploring experimental and computational markers of cyclic peptides: charting islands of permeability. European Journal of Medicinal Chemistry, 97, 202-213. doi: 10.1016/j.ejmech.2015.04.049 |
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2015 Journal Article In vivo efficacy of anuran rypsin inhibitory peptides against Staphylococcal Skin infection and the impact of peptide cyclizationMalik, U., Silva, O. N., Fensterseifer, I. C. M., Chan, A., Clark, R. J., Franco, O. L., Daly, N. L. and Craik, D. J. (2015). In vivo efficacy of anuran rypsin inhibitory peptides against Staphylococcal Skin infection and the impact of peptide cyclization. Antimicrobial Agents and Chemotherapy, 59 (4), 2113-2121. doi: 10.1128/AAC.04324-14 |
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2015 Journal Article Transcriptomic screening for cyclotides and other cysteine-rich proteins in the metallophyte Viola baoshanensisZhang, Jun, Li, Jintian, Huang, Zebo, Yang, Bing, Zhang, Xiaojie, Li, Dehua, Craik, David J., Baker, Alan J. M., Shu, Wensheng and Liao, Bin (2015). Transcriptomic screening for cyclotides and other cysteine-rich proteins in the metallophyte Viola baoshanensis. Journal of Plant Physiology, 178, 17-26. doi: 10.1016/j.jplph.2015.01.017 |
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2015 Journal Article Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA bindingZhangsun, Dongting, Zhu, Xiaopeng, Wu, Yong, Hu, Yuanyan, Kaas, Quentin, Craik, David J., McIntosh, J. Michael and Luo, Sulan (2015). Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding. The Journal of Biological Chemistry, 290 (15), 9855-9862. doi: 10.1074/jbc.M114.632646 |
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2015 Journal Article Solution structure, aggregation behavior, and flexibility of human relaxin-2Haugaard-Kedstrom, Linda, Hossain, Mohammed Akhter, Daly, Norelle L., Bathgate, Ross A. D., Rinderknecht, Ernst, Wade, John D., Craik, David J. and Rosengren, Karl Johan (2015). Solution structure, aggregation behavior, and flexibility of human relaxin-2. ACS Chemical Biology, 10 (3), 891-900. doi: 10.1021/cb500918v |
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2015 Journal Article Optimization of the cyclotide framework to improve cell penetration propertiesHuang, Yen-Hua, Chaousis, Steph, Cheneval, Olivier, Craik, David J. and Henriques, Sonia Troeira (2015). Optimization of the cyclotide framework to improve cell penetration properties. Frontiers in Pharmacology, 6 (17) 17, 1-7. doi: 10.3389/fphar.2015.00017 |
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2015 Journal Article Effects of cyclotides against cutaneous infections caused by Staphylococcus aureusFensterseifer, Isabel C. M., Silva, Osmar N., Malik, Uru, Ravipati, Anjaneya S., Novaes, Natasha R. F., Miranda, Paolo R. R., Rodrigues, Elaine A., Moreno, Susana E., Craik, David J. and Franco, Octavio L. (2015). Effects of cyclotides against cutaneous infections caused by Staphylococcus aureus. Peptides, 63 (3), 38-42. doi: 10.1016/j.peptides.2014.10.019 |
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2015 Journal Article Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreatBabbitt, Patricia C, Bagos, Pantelis G, Bairoch, Amos, Bateman, Alex, Chatonnet, Arnaud, Chen, Mark Jinan, Craik, David J, Finn, Robert D, Gloriam, David, Haft, Daniel H, Henrissat, Bernard, Holliday, Gemma L, Isberg, Vignir, Kaas, Quentin, Landsman, David, Lenfant, Nicolas, Manning, Gerard, Nagano, Nozomi, Srinivasan, Narayanaswamy, O'Donovan, Claire, Pruitt, Kim D, Sowdhamini, Ramanathan, Rawlings, Neil D, Saier Jr., Milton H, Sharman, Joanna L, Spedding, Michael, Tsirigos, Konstantinos D, Vastermark, Ake and Vriend, Gerrit (2015). Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database The Journal of Biological Databases and Curation, 2015 (bav063). doi: 10.1093/database/bav063 |
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2015 Journal Article Therapeutic conotoxins: a US patent literature surveyDurek, Thomas and Craik, David J. (2015). Therapeutic conotoxins: a US patent literature survey. Expert Opinion in Therapeutic Patents, 25 (10), 1159-1173. doi: 10.1517/13543776.2015.1054095 |
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2014 Journal Article Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databasesZhang, Jun, Hua, Zhengshuang, Huang, Zebo, Chen, QiZhu, Long, Qingyun, Craik, David J., Baker, Alan J. M., Shu, Wensheng and Liao, Bin (2014). Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases. Planta, 241 (4), 929-940. doi: 10.1007/s00425-014-2229-5 |
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2014 Journal Article Insights into the molecular flexibility of theta-defensins by NMR relaxation analysisConibear, Anne C., Wang, Conan K., Bi, Tao, Rosengren, K. Johan, Camarero, Julio A. and Craik, David J. (2014). Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis. Journal of Physical Chemistry B, 118 (49), 14257-14266. doi: 10.1021/jp507754c |
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2014 Journal Article Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclusVink, Simone, Daly, Norelle L., Steen, Natalie, Craik, David J. and Alewood, Paul F. (2014). Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus. Toxicon, 90 (1), 308-317. doi: 10.1016/j.toxicon.2014.08.068 |
