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2016 Journal Article Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxinCarstens, Bodil B., Swedberg, Joakim, Berecki, Geza, Adams, David J., Craik, David J. and Clark, Richard J. (2016). Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin. Biopolymers, 106 (6), 864-875. doi: 10.1002/bip.22848 |
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2016 Journal Article Forward for ICCP2015 issue of biopolymers peptide scienceCraik, David J. and Wang, Conan K. (2016). Forward for ICCP2015 issue of biopolymers peptide science. Biopolymers, 106 (6), 772-773. doi: 10.1002/bip.22989 |
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2016 Journal Article Discovery, isolation and structural characterization of cyclotides from Viola sumatrana miqNiyomploy, Ploypat, Chan, Lai Yue, Poth, Aaron G., Colgrave, Michelle L., Sangvanich, Polkit and Craik, David J. (2016). Discovery, isolation and structural characterization of cyclotides from Viola sumatrana miq. Biopolymers, 106 (6), 796-805. doi: 10.1002/bip.22914 |
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2016 Journal Article Cyclic peptide oral bioavailability: lessons from the pastWang, Conan K. and Craik, David J. (2016). Cyclic peptide oral bioavailability: lessons from the past. Biopolymers, 106 (6), 901-909. doi: 10.1002/bip.22878 |
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2016 Journal Article Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapyChan, LaiYue, Craik, David J. and Daly, Norelle L. (2016). Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy. Scientific Reports, 6 (1) 35347, 35347. doi: 10.1038/srep35347 |
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2016 Journal Article Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptideKwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C., Rosengren, K. Johan, Wang, Conan K., Schroeder, Christina I. and Craik, David J. (2016). Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering, 113 (10), 2202-2212. doi: 10.1002/bit.25993 |
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2016 Journal Article Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variantBleackley, Mark R., Payne, Jennifer A. E., Hayes, Brigitte M. E, Durek, Thomas, Craik, David J., Shafee, Thomas M. A., Poon, Ivan K. H., Hulett, Mark D., Van Der Weerden, Nicole L. and Anderson, Marilyn A. (2016). Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variant. Antimicrobial Agents and Chemotherapy, 60 (10), 6302-6312. doi: 10.1128/AAC.01479-16 |
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2016 Journal Article Accurate de novo design of hyperstable constrained peptidesBhardwaj, Gaurav, Mulligan, Vikram Khipple, Bahl, Christopher D., Gilmore, Jason M., Harvey, Peta J., Cheneval, Olivier, Buchko, Garry W., Pulavarti, Surya V. S. R. K., Kaas, Quentin, Eletsky, Alexander, Huang, Po-Ssu, Johnsen, William A., Greisen, Per Jr, Rocklin, Gabriel J., Song, Yifan, Linsky, Thomas W., Watkins, Andrew, Rettie, Stephen A., Xu, Xianzhong, Carter, Lauren P., Bonneau, Richard, Olson, James M., Coutsias, Evangelos, Correnti, Colin E., Szyperski, Thomas, Craik, David J. and Baker, David (2016). Accurate de novo design of hyperstable constrained peptides. Nature, 538 (7625), 329-335. doi: 10.1038/nature19791 |
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2016 Journal Article The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructuredDaly, Norelle L., Gunasekera, Sunithi, Clark, Richard J., Lin, Feng, Wade, John D., Anderson, Marilyn and Craik, David J. (2016). The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured. Biopolymers, 106 (6), 825-833. doi: 10.1002/bip.22977 |
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2016 Journal Article Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: an IUPAC Task Group interim reportCraik, David J., Youn Young Shim, Goransson, Ulf, Moss, Gerard P., Tan, Ninghua, Jadhav, Pramodkumar D., Shen, Jianheng and Reaney, Martin J. T. (2016). Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: an IUPAC Task Group interim report. Biopolymers, 106 (6), 917-924. doi: 10.1002/bip.22939 |
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2016 Journal Article Constrained cyclic peptides as immunomodulatory inhibitors of the CD2:CD58 protein-protein interactionSable, Rushikesh, Durek, Thomas, Taneja, Veena, Craik, David J., Pallerla, Sandeep, Gauthier, Ted and Jois, Seetharama (2016). Constrained cyclic peptides as immunomodulatory inhibitors of the CD2:CD58 protein-protein interaction. ACS Chemical Biology, 11 (8), 2366-2374. doi: 10.1021/acschembio.6b00486 |
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2016 Journal Article Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7Troeira Henriques, Sonia, Deplazes, Evelyne, Lawrence, Nicole, Cheneval, Olivier, Chaousis, Stephanie, Inserra, Marco, Thongyoo, Panumart, King, Glenn F., Mark, Alan E., Vetter, Irina, Craik, David J. and Schroeder, Christina Ingrid (2016). Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1.7. The Journal of Biological Chemistry, 291 (33), 17049-17065. doi: 10.1074/jbc.M116.729095 |
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2016 Journal Article Substrate-guided design of selective FXIIa inhibitors based on the plant-derived Momordica cochinchinensis trypsin inhibitor-II (MCoTI-II) scaffoldSwedberg, Joakim E., Mahatmanto, Tunjung, Ghani, Hafiza Abdul, de Veer, Simon J., Schroeder, Christina I., Harris, Jonathan M. and Craik, David J. (2016). Substrate-guided design of selective FXIIa inhibitors based on the plant-derived Momordica cochinchinensis trypsin inhibitor-II (MCoTI-II) scaffold. Journal of Medicinal Chemistry, 59 (15), 7287-7292. doi: 10.1021/acs.jmedchem.6b00557 |
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2016 Journal Article Truncated glucagon-like peptide-1 and exendin-4 α-conotoxin pl14a peptide chimeras maintain potency and α-helicity and reveal interactions vital for cAMP signaling in vitroSwedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Price, David A., Liras, Spiros and Craik, David J. (2016). Truncated glucagon-like peptide-1 and exendin-4 α-conotoxin pl14a peptide chimeras maintain potency and α-helicity and reveal interactions vital for cAMP signaling in vitro. Journal of Biological Chemistry, 291 (30), 15778-15787. doi: 10.1074/jbc.M116.724542 |
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2016 Journal Article Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016)Wu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Front Cover: Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications (Eur. J. Org. Chem. 21/2016). European Journal of Organic Chemistry, 2016 (21), 3457-3457. doi: 10.1002/ejoc.201670211 |
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2016 Journal Article Cyclisation of disulfide-rich conotoxins in drug design applicationsWu, Xiaosa, Huang, Yen-Hua, Kaas, Quentin and Craik, David J. (2016). Cyclisation of disulfide-rich conotoxins in drug design applications. European Journal of Organic Chemistry, 2016 (21), 3462-3472. doi: 10.1002/ejoc.201600402 |
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2016 Journal Article Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8Deuis, Jennifer R, Dekan, Zoltan, Inserra, Marco C., Lee, Tzong-Hsien, Aguilar, Marie-Isabel, Craik, David J., Lewis, Richard J., Alewood, Paul F., Mobli, Mehdi, Schroeder, Christina I., Henriques, Sónia Troeira and Vetter, Irina (2016). Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic target NaV1.8. Journal of Biological Chemistry, 291 (22), 11829-11842. doi: 10.1074/jbc.M116.721662 |
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2016 Journal Article Discovery, structure, function, and applications of cyclotides: circular proteins from plantsWeidmann, Joachim and Craik, David J. (2016). Discovery, structure, function, and applications of cyclotides: circular proteins from plants. Journal of Experimental Botany, 67 (16), 4801-4812. doi: 10.1093/jxb/erw210 |
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2016 Journal Article Biodistribution of the cyclotide MCoTI-II, a cyclic disulfide-rich peptide drug scaffoldWang, Conan K., Stalmans, Sofie, De Spiegeleer, Bart and Craik, David J. (2016). Biodistribution of the cyclotide MCoTI-II, a cyclic disulfide-rich peptide drug scaffold. Journal of Peptide Science, 22 (5), 305-310. doi: 10.1002/psc.2862 |
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2016 Journal Article Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional MotifCarstens, Bodil B., Berecki, Géza, Daniel, James T., Lee, Han Siean, Jackson, Kathryn A. V., Tae, Han-Shen, Sadeghi, Mahsa, Castro, Joel, O'Donnell, Tracy, Deiteren, Annemie, Brierley, Stuart M., Craik, David J., Adams, David J. and Clark, Richard J. (2016). Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie, 128 (15), 4770-4774. doi: 10.1002/ange.201600297 |
