Skip to menu Skip to content Skip to footer

2017

Journal Article

Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMR

Grage, Stephan L., Sani, Marc-Antoine, Cheneval, Olivier, Henriques, Sonia Troeira, Schalck, Constantin, Heinzmann, Ralf, Mylne, Joshua S., Mykhailiuk, Pavel K., Afonin, Sergii, Komarov, Igor V., Separovic, Frances, Craik, David J. and Ulrich, Anne S. (2017). Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMR. Biophysical Journal, 112 (4), 630-642. doi: 10.1016/j.bpj.2016.12.040

Orientation and location of the cyclotide kalata B1 in lipid bilayers revealed by solid-state NMR

2017

Journal Article

Cyclotide structure and function: the role of membrane binding and permeation

Troeira Henriques, Sonia and Craik, David J. (2017). Cyclotide structure and function: the role of membrane binding and permeation. Biochemistry, 56 (5), 669-682. doi: 10.1021/acs.biochem.6b01212

Cyclotide structure and function: the role of membrane binding and permeation

2017

Journal Article

Synthesis and protein engineering applications of cyclotides

Qu, Haiou, Smithies, Bronwyn J. , Durek, Thomas and Craik, David J. (2017). Synthesis and protein engineering applications of cyclotides. Australian Journal of Chemistry, 70 (2), 152-161. doi: 10.1071/CH16589

Synthesis and protein engineering applications of cyclotides

2017

Journal Article

Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold

Swedberg, Joakim E., Li, Choi Yi, De Veer, Simon J., Wang, Conan K. and Craik, David J. (2017). Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold. Journal of Medicinal Chemistry, 60 (2), 658-667. doi: 10.1021/acs.jmedchem.6b01509

Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold

2017

Journal Article

Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies

Abdul Ghani, Hafiza, Henriques, Sonia Troeira, Huang, Yen-Hua, Swedberg, Joakim E. , Schroeder, Christina I. and Craik, David J. (2017). Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies. Biopolymers, 108 (1) e22927, e22927. doi: 10.1002/bip.22927

Structural and functional characterization of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies

2017

Journal Article

Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells

Verbandt, Sara, Henriques, Sónia Troeira, Spincemaille, Pieter, Harvey, Peta J., Chandhok, Gursimran, Sauer, Vanessa, De Coninck, Barbara, Cassiman, David, Craik, David J., Cammue, Bruno P. A., De Cremer, Kaat and Thevissen, Karin (2017). Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells. Mechanisms of Ageing and Development, 161 (B), 247-254. doi: 10.1016/j.mad.2016.07.013

Identification of survival-promoting OSIP108 peptide variants and their internalization in human cells

2016

Journal Article

Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloids

Matsuura, Helio N., Poth, Aaron G., Yendo, Anna C. A., Fett-Neto, Arthur G. and Craik, David J. (2016). Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloids. Journal of Natural Products, 79 (12), 3006-3013. doi: 10.1021/acs.jnatprod.6b00492

Isolation and characterization of cyclotides from Brazilian Psychotria: significance in plant defense and co-occurrence with antioxidant alkaloids

2016

Journal Article

Discovery and optimization of peptide macrocycles

White, Andrew M. and Craik, David J. (2016). Discovery and optimization of peptide macrocycles. Expert Opinion on Drug Discovery, 11 (12), 1151-1163. doi: 10.1080/17460441.2016.1245720

Discovery and optimization of peptide macrocycles

2016

Journal Article

Characterization of a bioactive acyclotide from Palicourea rigida

Pinto, Michelle F. S., Silva, Osmar N., Viana, Juilan C., Porto, William F., Migliolo, Ludovico, da Cunha, Nicolau B., Gomes Jr., Nelson, Fensterseifer, Isabel C. M., Colgrave, Michelle L., Craik, David J., Dias, Simoni C. and Franco, Octavio L. (2016). Characterization of a bioactive acyclotide from Palicourea rigida. Journal of Natural Products, 79 (11), 2767-2773. doi: 10.1021/acs.jnatprod.6b00270

Characterization of a bioactive acyclotide from Palicourea rigida

2016

Journal Article

Discovery, isolation and structural characterization of cyclotides from Viola sumatrana miq

Niyomploy, Ploypat, Chan, Lai Yue, Poth, Aaron G., Colgrave, Michelle L., Sangvanich, Polkit and Craik, David J. (2016). Discovery, isolation and structural characterization of cyclotides from Viola sumatrana miq. Biopolymers, 106 (6), 796-805. doi: 10.1002/bip.22914

Discovery, isolation and structural characterization of cyclotides from Viola sumatrana miq

2016

Journal Article

Cyclic peptide oral bioavailability: lessons from the past

Wang, Conan K. and Craik, David J. (2016). Cyclic peptide oral bioavailability: lessons from the past. Biopolymers, 106 (6), 901-909. doi: 10.1002/bip.22878

Cyclic peptide oral bioavailability: lessons from the past

2016

Journal Article

Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin

Carstens, Bodil B., Swedberg, Joakim, Berecki, Geza, Adams, David J., Craik, David J. and Clark, Richard J. (2016). Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin. Biopolymers, 106 (6), 864-875. doi: 10.1002/bip.22848

Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin

2016

Journal Article

Forward for ICCP2015 issue of biopolymers peptide science

Craik, David J. and Wang, Conan K. (2016). Forward for ICCP2015 issue of biopolymers peptide science. Biopolymers, 106 (6), 772-773. doi: 10.1002/bip.22989

Forward for ICCP2015 issue of biopolymers peptide science

2016

Journal Article

Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy

Chan, LaiYue, Craik, David J. and Daly, Norelle L. (2016). Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy. Scientific Reports, 6 (1) 35347, 35347. doi: 10.1038/srep35347

Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy

2016

Journal Article

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

Kwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C., Rosengren, K. Johan, Wang, Conan K., Schroeder, Christina I. and Craik, David J. (2016). Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering, 113 (10), 2202-2212. doi: 10.1002/bit.25993

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

2016

Journal Article

Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variant

Bleackley, Mark R., Payne, Jennifer A. E., Hayes, Brigitte M. E, Durek, Thomas, Craik, David J., Shafee, Thomas M. A., Poon, Ivan K. H., Hulett, Mark D., Van Der Weerden, Nicole L. and Anderson, Marilyn A. (2016). Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variant. Antimicrobial Agents and Chemotherapy, 60 (10), 6302-6312. doi: 10.1128/AAC.01479-16

Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variant

2016

Journal Article

Accurate de novo design of hyperstable constrained peptides

Bhardwaj, Gaurav, Mulligan, Vikram Khipple, Bahl, Christopher D., Gilmore, Jason M., Harvey, Peta J., Cheneval, Olivier, Buchko, Garry W., Pulavarti, Surya V. S. R. K., Kaas, Quentin, Eletsky, Alexander, Huang, Po-Ssu, Johnsen, William A., Greisen, Per Jr, Rocklin, Gabriel J., Song, Yifan, Linsky, Thomas W., Watkins, Andrew, Rettie, Stephen A., Xu, Xianzhong, Carter, Lauren P., Bonneau, Richard, Olson, James M., Coutsias, Evangelos, Correnti, Colin E., Szyperski, Thomas, Craik, David J. and Baker, David (2016). Accurate de novo design of hyperstable constrained peptides. Nature, 538 (7625), 329-335. doi: 10.1038/nature19791

Accurate de novo design of hyperstable constrained peptides

2016

Journal Article

The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured

Daly, Norelle L., Gunasekera, Sunithi, Clark, Richard J., Lin, Feng, Wade, John D., Anderson, Marilyn and Craik, David J. (2016). The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured. Biopolymers, 106 (6), 825-833. doi: 10.1002/bip.22977

The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured

2016

Journal Article

Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: an IUPAC Task Group interim report

Craik, David J., Youn Young Shim, Goransson, Ulf, Moss, Gerard P., Tan, Ninghua, Jadhav, Pramodkumar D., Shen, Jianheng and Reaney, Martin J. T. (2016). Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: an IUPAC Task Group interim report. Biopolymers, 106 (6), 917-924. doi: 10.1002/bip.22939

Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: an IUPAC Task Group interim report

2016

Journal Article

Constrained cyclic peptides as immunomodulatory inhibitors of the CD2:CD58 protein-protein interaction

Sable, Rushikesh, Durek, Thomas, Taneja, Veena, Craik, David J., Pallerla, Sandeep, Gauthier, Ted and Jois, Seetharama (2016). Constrained cyclic peptides as immunomodulatory inhibitors of the CD2:CD58 protein-protein interaction. ACS Chemical Biology, 11 (8), 2366-2374. doi: 10.1021/acschembio.6b00486

Constrained cyclic peptides as immunomodulatory inhibitors of the CD2:CD58 protein-protein interaction