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2019 Journal Article Site-specific sequential protein labeling catalyzed by a single recombinant ligaseRehm, Fabian B. H., Harmand, Thibault J., Yap, Kuok, Durek, Thomas, Craik, David J. and Ploegh, Hidde L. (2019). Site-specific sequential protein labeling catalyzed by a single recombinant ligase. Journal of the American Chemical Society, 141 (43) jacs.9b09166, 17388-17393. doi: 10.1021/jacs.9b09166 |
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2019 Journal Article Conotoxins: chemistry and biologyJin, Ai-Hua, Muttenthaler, Markus, Dutertre, Sebastien, Himaya, S.W.A., Kaas, Quentin, Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2019). Conotoxins: chemistry and biology. Chemical Reviews, 119 (21), 11510-11549. doi: 10.1021/acs.chemrev.9b00207 |
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2019 Journal Article Evaluation of cyclic peptide inhibitors of the Grb7 breast cancer target: small change in cargo results in large change in cellular activitySang, Jianrong, Kulkarni, Ketav, Watson, Gabrielle M., Ma, Xiuquan, Craik, David J., Henriques, Sónia T., Poth, Aaron G., Benfield, Aurélie H. and Wilce, Jacqueline A. (2019). Evaluation of cyclic peptide inhibitors of the Grb7 breast cancer target: small change in cargo results in large change in cellular activity. Molecules, 24 (20) 3739, 3739. doi: 10.3390/molecules24203739 |
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2019 Journal Article In Silico design of MDM2-targeting peptides from a naturally occurring constrained peptideMa, He, Qiu, Peiju, Harvey, Peta J., Li, Xiao, Zhang, Zheyu, Xu, Qingliang, Liang, Jiazhen, Kaas, Quentin, Craik, David J., Yang, Jinbo, Jiang, Tao, Bi, Xiaolin and Yu, Rilei (2019). In Silico design of MDM2-targeting peptides from a naturally occurring constrained peptide. Chemmedchem, 14 (19) cmdc.201900366, 1710-1716. doi: 10.1002/cmdc.201900366 |
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2019 Journal Article Computer-aided design of mastoparan-like peptides enables the generation of nontoxic variants with extended antibacterial propertiesOshiro, Karen G. N., Cândido, Elizabete S., Chan, Lai Y., Torres, Marcelo D. T., Monges, Bruna E. D., Rodrigues, Silvia G., Porto, William F., Ribeiro, Suzana M., Henriques, Sónia T., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J., Franco, Octávio L. and Cardoso, Marlon H. (2019). Computer-aided design of mastoparan-like peptides enables the generation of nontoxic variants with extended antibacterial properties. Journal of Medicinal Chemistry, 62 (17), 8140-8151. doi: 10.1021/acs.jmedchem.9b00915 |
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2019 Journal Article Characterization of tachyplesin peptides and their cyclized analogues to improve antimicrobial and anticancer propertiesVernen, Felicitas, Harvey, Peta J., Dias, Susana A., Veiga, Ana Salomé, Huang, Yen-Hua, Craik, David J., Lawrence, Nicole and Troeira Henriques, Sónia (2019). Characterization of tachyplesin peptides and their cyclized analogues to improve antimicrobial and anticancer properties. International Journal of Molecular Sciences, 20 (17) 4184, 4184. doi: 10.3390/ijms20174184 |
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2019 Journal Article Cell membrane composition drives selectivity and toxicity of designed cyclic helix-loop-helix peptides with cell penetrating and tumor suppressor propertiesPhilippe, Grégoire J. -B., Gaspar, Diana, Sheng, Caibin, Huang, Yen-Hua, Benfield, Aurélie H., Condon, Nicholas D., Weidmann, Joachim, Lawrence, Nicole, Löwer, Alexander, Castanho, Miguel A. R. B., Craik, David J. and Troeira Henriques, Sónia (2019). Cell membrane composition drives selectivity and toxicity of designed cyclic helix-loop-helix peptides with cell penetrating and tumor suppressor properties. ACS Chemical Biology, 14 (9), 2071-2087. doi: 10.1021/acschembio.9b00593 |
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2019 Journal Article A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered proteinHarris, Karen S., Guarino, Rosemary F., Dissanayake, Ravindu S., Quimbar, Pedro, McCorkelle, Owen C., Poon, Simon, Kaas, Quentin, Durek, Thomas, Gilding, Edward K., Jackson, Mark A., Craik, David J., van der Weerden, Nicole L., Anders, Robin F. and Anderson, Marilyn A. (2019). A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein. Scientific Reports, 9 (1) 10820, 10820. doi: 10.1038/s41598-019-47273-7 |
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2019 Journal Article Iterative optimization of the cyclic peptide SFTI-1 yields potent inhibitors of neutrophil proteinase 3Tian, Sixin, Swedberg, Joakim E., Li, Choi Yi, Craik, David J. and de Veer, Simon J. (2019). Iterative optimization of the cyclic peptide SFTI-1 yields potent inhibitors of neutrophil proteinase 3. ACS Medicinal Chemistry Letters, 10 (8) acsmedchemlett.9b00253, 1234-1239. doi: 10.1021/acsmedchemlett.9b00253 |
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2019 Journal Article Short cationic peptide derived from archaea with dual antibacterial properties and anti-infective potentialCândido, Elizabete S., Cardoso, Marlon H., Chan, Lai Y., Torres, Marcelo D. T., Oshiro, Karen G. N., Porto, William F., Ribeiro, Suzana M., Haney, Evan F., Hancock, Robert E. W., Lu, Timothy K., de la Fuente-Nunez, Cesar, Craik, David J. and Franco, Octávio L. (2019). Short cationic peptide derived from archaea with dual antibacterial properties and anti-infective potential. ACS Infectious Diseases, 5 (7) acsinfecdis.9b00073, 1081-1086. doi: 10.1021/acsinfecdis.9b00073 |
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2019 Journal Article The vast structural diversity of antimicrobial peptidesKoehbach, Johannes and Craik, David J. (2019). The vast structural diversity of antimicrobial peptides. Trends in Pharmacological Sciences, 40 (7), 517-528. doi: 10.1016/j.tips.2019.04.012 |
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2019 Journal Article Pharmacokinetic characterization of kalata B1 and related therapeutics built on the cyclotide scaffoldPoth, Aaron G., Huang, Yen-Hua, Le, Thao T., Kan, Meng-Wei and Craik, David J. (2019). Pharmacokinetic characterization of kalata B1 and related therapeutics built on the cyclotide scaffold. International Journal of Pharmaceutics, 565, 437-446. doi: 10.1016/j.ijpharm.2019.05.001 |
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2019 Journal Article Efficient enzymatic cyclization of disulfide-rich peptides by using peptide ligasesSchmidt, Marcel, Huang, Yen-Hua, de Oliveira, Eduardo F. Texeira, Toplak, Ana, Wijma, Hein J., Janssen, Dick B., van Maarseveen, Jan H., Craik, David J. and Nuijens, Timo (2019). Efficient enzymatic cyclization of disulfide-rich peptides by using peptide ligases. ChemBioChem, 20 (12) cbic.201900033, 1524-1529. doi: 10.1002/cbic.201900033 |
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2019 Journal Article Anchor residues guide form and function in grafted peptidesYin, Huawu, Craik, David J. and Wang, Conan K. (2019). Anchor residues guide form and function in grafted peptides. Angewandte Chemie International Edition, 58 (23), 7652-7656. doi: 10.1002/anie.201901572 |
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2019 Journal Article Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptorChambers, Chris, Cutler, Penny, Huang, Yen-Hua, Goodchild, James A., Blythe, Judith, Wang, Conan K., Bigot, Aurélien, Kaas, Quentin, Craik, David J., Sabbadin, Davide and Earley, Fergus G. (2019). Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor. FEBS Letters, 593 (12) 1873-3468.13435, 1336-1350. doi: 10.1002/1873-3468.13435 |
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2019 Journal Article Chemical synthesis, proper folding, Na-v channel selectivity profile and analgesic properties of the spider peptide phlotoxin 1Nicolas, Sebastien, Zoukimian, Claude, Bosmans, Frank, Montnach, Jerome, Diochot, Sylvie, Cuypers, Eva, De Waard, Stephan, Beroud, Remy, Mebs, Dietrich, Craik, David, Boturyn, Didier, Lazdunski, Michel, Tytgat, Jan and De Waard, Michel (2019). Chemical synthesis, proper folding, Na-v channel selectivity profile and analgesic properties of the spider peptide phlotoxin 1. Toxins, 11 (6) 367, 367. doi: 10.3390/toxins11060367 |
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2019 Journal Article Anchor residues guide form and function in grafted peptidesYin, Huawu, Craik, David J. and Wang, Conan K. (2019). Anchor residues guide form and function in grafted peptides. Angewandte Chemie, 131 (23), 7734-7738. doi: 10.1002/ange.201901572 |
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2019 Journal Article Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChREl Hamdaoui, Yamina, Wu, Xiaosa, Clark, Richard J., Giribaldi, Julien, Anangi, Raveendra, Craik, David J., King, Glenn F., Dutertre, Sebastien, Kaas, Quentin, Herzig, Volker and Nicke, Annette (2019). Periplasmic expression of 4/7 alpha-conotoxin TxIA analogs in E. coli favors ribbon isomer formation suggestion of a binding mode at the α7 nAChR. Frontiers in Pharmacology, 10 (MAY) 577, 577. doi: 10.3389/fphar.2019.00577 |
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2019 Journal Article Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicineOguis, Georgianna K., Gilding, Edward K., Jackson, Mark A. and Craik, David J. (2019). Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine. Frontiers in Plant Science, 10 645, 645. doi: 10.3389/fpls.2019.00645 |
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2019 Journal Article Rapid and scalable plant-based production of a potent plasmin inhibitor peptideJackson, Mark A., Yap, Kuok, Poth, Aaron G., Gilding, Edward K., Swedberg, Joakim E., Poon, Simon, Qu, Haiou, Durek, Thomas, Harris, Karen, Anderson, Marilyn A. and Craik, David J. (2019). Rapid and scalable plant-based production of a potent plasmin inhibitor peptide. Frontiers in Plant Science, 10 602, 602. doi: 10.3389/fpls.2019.00602 |
