Skip to menu Skip to content Skip to footer
Professor Elizabeth Krenske
Professor

Elizabeth Krenske

Email: 
Phone: 
+61 7 336 54632

Overview

Background

Professor Elizabeth Krenske leads a computational chemistry laboratory that specialises in understanding molecular behaviour. Her laboratory has a particular focus on the study of chemical reaction mechanisms, including the computational prediction of reaction outcomes. Prof. Krenske obtained her PhD in synthetic main-group chemistry at The Australian National University's Research School of Chemistry, where she worked with Professor Bruce Wild. After two years of postdoctoral research at the ANU she was awarded a Fulbright Postdoctoral Scholarship and spent two years at the University of California, Los Angeles, working in the field of theoretical and computational chemistry with Professor Kendall Houk. She returned to Australia in 2009 as an ARC Australian Postdoctoral Fellow at the University of Melbourne, and moved to The University of Queensland in 2012 as an ARC Future Fellow. She is currently a Professor in the UQ School of Chemistry and Molecular Biosciences.

Prof. Krenske is a Fellow of the Royal Australian Chemical Institute, Fellow of the Royal Society of Chemistry, Fellow of the Higher Education Academy and former Associate Editor of the RSC journal Organic & Biomolecular Chemistry.

Availability

Professor Elizabeth Krenske is:
Available for supervision

Qualifications

  • Bachelor of Science, The University of Queensland
  • Doctor of Philosophy, Australian National University

Works

Search Professor Elizabeth Krenske’s works on UQ eSpace

129 works between 2002 and 2024

61 - 80 of 129 works

2017

Journal Article

Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions

Lombard, Fanny J, Lepage, Romain J, Schwartz, Brett D, Johnston, Ryne C, Healy, Peter C, Krenske, Elizabeth H and Coster, Mark J (2017). Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions. Organic & biomolecular chemistry, 16 (2), 256-261. doi: 10.1039/c7ob02123b

Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions

2017

Journal Article

(4+3) Cycloaddition reactions of N-alkyl oxidopyridinium ions

Fu, Chencheng, Lora, Nestor, Kirchhoefer, Patrick L., Lee, Dong Reyoul, Altenhofer, Erich, Barnes, Charles L., Hungerford, Natasha L., Krenske, Elizabeth H. and Harmata, Michael (2017). (4+3) Cycloaddition reactions of N-alkyl oxidopyridinium ions. Angewandte Chemie (International Edition), 56 (46), 14682-14687. doi: 10.1002/anie.201708320

(4+3) Cycloaddition reactions of N-alkyl oxidopyridinium ions

2017

Journal Article

Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity

Krenske, Elizabeth H., Burns, Jed M. and McGeary, Ross P. (2017). Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity. Organic and Biomolecular Chemistry, 15 (37), 7887-7893. doi: 10.1039/c7ob01666b

Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity

2017

Journal Article

Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization

Manchala, Narasimhulu, Law, Hanson Y. L., Kerr, Daniel J., Volpe, Rohan, Lepage, Romain J., White, Jonathan M., Krenske, Elizabeth H. and Flynn, Bernard L. (2017). Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization. Journal of Organic Chemistry, 82 (13), 6511-6527. doi: 10.1021/acs.joc.7b00082

Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization

2017

Journal Article

An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone

Fisher, Brendan, Lepage, Romain J., White, Jonathan M., Ye, Young, Krenske, Elizabeth H. and Rizzacasa, Mark A. (2017). An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone. Organic & Biomolecular Chemistry, 15 (26), 5529-5534. doi: 10.1039/c7ob01121k

An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone

2017

Journal Article

Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide

Banerjee, Shibdas, Yang, Yun-Fang, Jenkins, Ian D., Liang, Yong, Toutov, Anton A., Liu, Wen-Bo, Schuman, David P., Grubbs, Robert H., Stoltz, Brian M., Krenske, Elizabeth H., Houk, Kendall N. and Zare, Richard N. (2017). Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide. Journal of the American Chemical Society, 139 (20), 6880-6887. doi: 10.1021/jacs.6b13032

Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide

2017

Journal Article

Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations

Lovie-Toon, Joseph P., Tram, Camilla Mia, Flynn, Bernard L. and Krenske, Elizabeth H. (2017). Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations. Acs Catalysis, 7 (5), 3466-3476. doi: 10.1021/acscatal.7b00292

Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations

2017

Journal Article

Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates

Burns, Jed M., Krenske, Elizabeth H. and McGeary, Ross P. (2017). Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates. European Journal of Organic Chemistry, 2017 (2), 252-256. doi: 10.1002/ejoc.201601354

Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates

2017

Journal Article

Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols

Moore, Peter W., Hooker, Jordan P., Zavra, Athanasios, Khairallah, George N., Krenske, Elizabeth H., Bernhardt, Paul V., Quach, Gina, Moore, Evan G., O’Hair, Richard A. J. and William, Craig M. (2017). Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols. Australian Journal of Chemistry, 70 (4), 397-406. doi: 10.1071/CH16602

Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols

2016

Journal Article

Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines

Krenske, Elizabeth H., Petter, Russell C. and Houk, K. N. (2016). Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines. Journal of Organic Chemistry, 81 (23), 11726-11733. doi: 10.1021/acs.joc.6b02188

Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines

2016

Journal Article

The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations

Mohamed, Shifaza, Krenske, Elizabeth H. and Ferro, Vito (2016). The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations. Organic and Biomolecular Chemistry, 14 (10), 2950-2960. doi: 10.1039/C6OB00283H

The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations

2016

Journal Article

Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation

Stok, Jeanette E., Chow, Sharon, Krenske, Elizabeth H., Farfan Soto, Clementina, Matyas, Csongor, Poirier, Raymond A., Williams, Craig M. and De Voss, James J. (2016). Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation. Chemistry: A European Journal, 22 (13), 4408-4412. doi: 10.1002/chem.201600246

Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation

2016

Journal Article

Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases

Brown, Joshua J., Gahan, Lawrence R., Schöffler, Anne, Krenske, Elizabeth H. and Schenk, Gerhard (2016). Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases. Journal of Inorganic Biochemistry, 162, 356-365. doi: 10.1016/j.jinorgbio.2016.02.008

Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases

2016

Other Outputs

Olefin strain energy as a predictor of isolability

Krenske, Elizabeth H. and Williams, Craig M. (2016). Olefin strain energy as a predictor of isolability. The University of Queensland. (Dataset) doi: 10.14264/uql.2016.208

Olefin strain energy as a predictor of isolability

2015

Journal Article

Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides

Cameron, Alex, Fisher, Brendan, Fisk, Nicholas, Hummel, Jessica, White, Jonathan M., Krenske, Elizabeth H. and Rizzacasa, Mark A. (2015). Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides. Organic Letters, 17 (24), 5998-6001. doi: 10.1021/acs.orglett.5b02965

Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides

2015

Journal Article

Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability

Krenske, Elizabeth H. and Williams, Craig M. (2015). Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability. Angewandte Chemie International Edition, 54 (36), 10608-10612. doi: 10.1002/anie.201503822

Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability

2015

Journal Article

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

Challinor, Victoria L., Johnston, Ryne C., Bernhardt, Paul V., Lehmann, Reginald P., Krenske, Elizabeth H. and De Voss, James J. (2015). Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa. Chemical Science, 6 (10), 5740-5745. doi: 10.1039/c5sc02056e

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

2015

Journal Article

Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata

White, Andrew M., Pierens, Gregory K., Skinner-Adams, Tina, Andrews, Katherine T., Bernhardt, Paul V., Krenske, Elizabeth H., Mollo, Ernesto and Garson, Mary J. (2015). Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata. Journal of Natural Products, 78 (6), 1422-1427. doi: 10.1021/acs.jnatprod.5b00354

Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata

2015

Journal Article

Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes

Krenske, Elizabeth H., Lam, Sarah, Ng, Jerome P. L., Lo, Brian, Lam, Sze Kui, Chiu, Pauline and Houk, Kendall N. (2015). Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes. Angewandte Chemie (International Edition), 54 (25), 7422-7425. doi: 10.1002/anie.201503003

Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes

2015

Journal Article

Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

Volpe, Rohan, Aurelio, Luigi, Gillin, Murray G., Krenske, Elizabeth H. and Flynn, Bernard L. (2015). Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations. Chemistry - A European Journal, 21 (28), 10191-10199. doi: 10.1002/chem.201500384

Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

Funding

Current funding

  • 2022 - 2025
    Opening Up Access to L-Sugars through a Synergy of Experiment and Theory
    ARC Discovery Projects
    Open grant

Past funding

  • 2018 - 2022
    Computational Tools for Organic Synthesis
    ARC Discovery Projects
    Open grant
  • 2017 - 2020
    New Computational Technology to Drive Innovation in Molecular Science
    UQ Development Fellowships
    Open grant
  • 2017 - 2021
    Large area opto-electronics for Australia and India: from materials to advanced devices
    Department of Industry, Innovation, and Science - Australia-India Strategic Research Fund
    Open grant
  • 2015 - 2017
    Chiral Catalysts by Rational Design (ARC Discovery Project administered by Monash University)
    Monash University
    Open grant
  • 2014
    A parallel computer facility for modelling and simulation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2017
    Theoretical modelling and design of safe covalent anti-cancer drugs
    ARC Future Fellowships
    Open grant

Supervision

Availability

Professor Elizabeth Krenske is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Molecular modelling. Chemical Reactivity. Catalysis. Drug Design.

Supervision history

Current supervision

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Development of new computational techniques for carbohydrate and agricultural chemistry

    Principal Advisor

    Other advisors: Professor Vito Ferro

  • Doctor Philosophy

    Synthesis of L-sugars via radical chemistry

    Associate Advisor

    Other advisors: Professor Vito Ferro

  • Doctor Philosophy

    Insight into Nonequilibrium Behaviour from Molecular Simulations

    Associate Advisor

    Other advisors: Professor Debra Bernhardt

Completed supervision

Media

Enquiries

For media enquiries about Professor Elizabeth Krenske's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au