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Professor Elizabeth Krenske
Professor

Elizabeth Krenske

Email: 
Phone: 
+61 7 336 54632

Overview

Background

Professor Elizabeth Krenske leads a computational chemistry laboratory that specialises in understanding molecular behaviour. Her laboratory has a particular focus on the study of chemical reaction mechanisms, including the computational prediction of reaction outcomes. Prof. Krenske obtained her PhD in synthetic main-group chemistry at The Australian National University's Research School of Chemistry, where she worked with Professor Bruce Wild. After two years of postdoctoral research at the ANU she was awarded a Fulbright Postdoctoral Scholarship and spent two years at the University of California, Los Angeles, working in the field of theoretical and computational chemistry with Professor Kendall Houk. She returned to Australia in 2009 as an ARC Australian Postdoctoral Fellow at the University of Melbourne, and moved to The University of Queensland in 2012 as an ARC Future Fellow. She is currently a Professor in the UQ School of Chemistry and Molecular Biosciences.

Prof. Krenske is a Fellow of the Royal Australian Chemical Institute, Fellow of the Royal Society of Chemistry, Fellow of the Higher Education Academy and former Associate Editor of the RSC journal Organic & Biomolecular Chemistry.

Availability

Professor Elizabeth Krenske is:
Available for supervision

Qualifications

  • Bachelor of Science, The University of Queensland
  • Doctor of Philosophy, Australian National University

Works

Search Professor Elizabeth Krenske’s works on UQ eSpace

138 works between 2002 and 2024

61 - 80 of 138 works

2018

Journal Article

Mechanistic studies on the base-promoted conversion of alkoxy-substituted, ring-fused gem-dihalocyclopropanes into furans: evidence for a process involving electrocyclic ring closure of a carbonyl ylide intermediate

Sharp, Phillip P., Mikusek, Jiri, Ho, Junming, Krenske, Elizabeth H., Banwell, Martin G., Coote, Michelle L., Ward, Jas S. and Willis, Anthony C. (2018). Mechanistic studies on the base-promoted conversion of alkoxy-substituted, ring-fused gem-dihalocyclopropanes into furans: evidence for a process involving electrocyclic ring closure of a carbonyl ylide intermediate. The Journal of Organic Chemistry, 83 (22) acs.joc.8b01766, 13678-13690. doi: 10.1021/acs.joc.8b01766

Mechanistic studies on the base-promoted conversion of alkoxy-substituted, ring-fused gem-dihalocyclopropanes into furans: evidence for a process involving electrocyclic ring closure of a carbonyl ylide intermediate

2018

Journal Article

Synthesis, magnetic properties, and catalytic properties of a nickel(II)-dependent biomimetic of metallohydrolases

Horn, Adolfo, Englert, Daniel, Roberts, Asha E., Comba, Peter, Schenk, Gerhard, Krenske, Elizabeth H. and Gahan, Lawrence R. (2018). Synthesis, magnetic properties, and catalytic properties of a nickel(II)-dependent biomimetic of metallohydrolases. Frontiers in Chemistry, 6 441, 441. doi: 10.3389/fchem.2018.00441

Synthesis, magnetic properties, and catalytic properties of a nickel(II)-dependent biomimetic of metallohydrolases

2018

Journal Article

Front cover: developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer (Eur. J. Org. Chem. /2018)

Xie, Sida, Savchenko, Andrei I., Krenske, Elizabeth H., Grange, Rebecca L., Gahan, Lawrence R. and Williams, Craig M. (2018). Front cover: developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer (Eur. J. Org. Chem. /2018). European Journal of Organic Chemistry, 2018 (25), 3246-3246. doi: 10.1002/ejoc.201800902

Front cover: developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer (Eur. J. Org. Chem. /2018)

2018

Journal Article

Developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer

Xie, Sida, Savchenko, Andrei I., Krenske, Elizabeth H., Grange, Rebecca L., Gahan, Lawrence R. and Williams, Craig M. (2018). Developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer. European Journal of Organic Chemistry, 2018 (25), 3265-3270. doi: 10.1002/ejoc.201800449

Developing cyclic peptide heteroatom interchange: synthesis and DFT modelling of a HI-ascidiacyclamide isomer

2018

Journal Article

Glycosylations of simple acceptors with 2-O-acyl L-idose or L-iduronic acid donors reveal only a minor role for neighbouring-group participation

Mohamed, Shifaza, He, Qi Qi, Lepage, Romain J., Krenske, Elizabeth H. and Ferro, Vito (2018). Glycosylations of simple acceptors with 2-O-acyl L-idose or L-iduronic acid donors reveal only a minor role for neighbouring-group participation. European Journal of Organic Chemistry, 2018 (19), 2214-2227. doi: 10.1002/ejoc.201800318

Glycosylations of simple acceptors with 2-O-acyl L-idose or L-iduronic acid donors reveal only a minor role for neighbouring-group participation

2018

Journal Article

Asymmetric synthesis of multiple quaternary stereocentre-containing cyclopentyls by oxazolidinone-promoted Nazarov cyclizations

Volpe, Rohan, Lepage, Romain J., White, Jonathan M., Krenske, Elizabeth H. and Flynn, Bernard L. (2018). Asymmetric synthesis of multiple quaternary stereocentre-containing cyclopentyls by oxazolidinone-promoted Nazarov cyclizations. Chemical Science, 9 (20), 4644-4649. doi: 10.1039/c8sc00031j

Asymmetric synthesis of multiple quaternary stereocentre-containing cyclopentyls by oxazolidinone-promoted Nazarov cyclizations

2018

Journal Article

Heteroatom-Interchanged Isomers of Lissoclinamide 5: Copper(II) Complexation, Halide Binding, and Biological Activity

Xie, Sida, Savchenko, Andrei I., Kerscher, Marion, Grange, Rebecca L., Krenske, Elizabeth H., Harmer, Jeffrey R., Bauer, Michelle J., Broit, Natasa, Watters, Dianne J., Boyle, Glen M., Bernhardt, Paul V., Parsons, Peter G., Comba, Peter, Gahan, Lawrence R. and Williams, Craig M. (2018). Heteroatom-Interchanged Isomers of Lissoclinamide 5: Copper(II) Complexation, Halide Binding, and Biological Activity. European Journal of Organic Chemistry, 2018 (12), 1465-1476. doi: 10.1002/ejoc.201701659

Heteroatom-Interchanged Isomers of Lissoclinamide 5: Copper(II) Complexation, Halide Binding, and Biological Activity

2018

Journal Article

Claisen rearrangements of benzyl vinyl ethers and heterobenzyl vinyl ethers

Burns, Jed M., Krenske, Elizabeth H. and Mcgeary, Ross P. (2018). Claisen rearrangements of benzyl vinyl ethers and heterobenzyl vinyl ethers. Synthesis, 50 (9) ss-2017-e0731-r, 1750-1772. doi: 10.1055/s-0036-1589529

Claisen rearrangements of benzyl vinyl ethers and heterobenzyl vinyl ethers

2018

Book Chapter

Challenges in predicting stereoselectivity

Krenske, Elizabeth H. (2018). Challenges in predicting stereoselectivity. Applied theoretical organic chemistry. (pp. 583-604) edited by Dean J. Tantillo. Covent Garden, London, United Kingdom: World Scientific Publishing. doi: 10.1142/9781786344090_0019

Challenges in predicting stereoselectivity

2017

Journal Article

Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions

Lombard, Fanny J, Lepage, Romain J, Schwartz, Brett D, Johnston, Ryne C, Healy, Peter C, Krenske, Elizabeth H and Coster, Mark J (2017). Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions. Organic & biomolecular chemistry, 16 (2), 256-261. doi: 10.1039/c7ob02123b

Synthesis of spirocyclic orthoesters by 'anomalous' rhodium(ii)-catalysed intramolecular C-H insertions

2017

Journal Article

(4+3) Cycloaddition reactions of N-alkyl oxidopyridinium ions

Fu, Chencheng, Lora, Nestor, Kirchhoefer, Patrick L., Lee, Dong Reyoul, Altenhofer, Erich, Barnes, Charles L., Hungerford, Natasha L., Krenske, Elizabeth H. and Harmata, Michael (2017). (4+3) Cycloaddition reactions of N-alkyl oxidopyridinium ions. Angewandte Chemie (International Edition), 56 (46), 14682-14687. doi: 10.1002/anie.201708320

(4+3) Cycloaddition reactions of N-alkyl oxidopyridinium ions

2017

Journal Article

Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity

Krenske, Elizabeth H., Burns, Jed M. and McGeary, Ross P. (2017). Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity. Organic and Biomolecular Chemistry, 15 (37), 7887-7893. doi: 10.1039/c7ob01666b

Claisen rearrangements of benzyl vinyl ethers: theoretical investigation of mechanism, substituent effects, and regioselectivity

2017

Journal Article

Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization

Manchala, Narasimhulu, Law, Hanson Y. L., Kerr, Daniel J., Volpe, Rohan, Lepage, Romain J., White, Jonathan M., Krenske, Elizabeth H. and Flynn, Bernard L. (2017). Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization. Journal of Organic Chemistry, 82 (13), 6511-6527. doi: 10.1021/acs.joc.7b00082

Multistereocenter-containing cyclopentanoids from Ynamides via oxazolidinone-controlled nazarov cyclization

2017

Journal Article

An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone

Fisher, Brendan, Lepage, Romain J., White, Jonathan M., Ye, Young, Krenske, Elizabeth H. and Rizzacasa, Mark A. (2017). An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone. Organic & Biomolecular Chemistry, 15 (26), 5529-5534. doi: 10.1039/c7ob01121k

An unprecedented stereoselective base-induced trimerization of an α-bromovinylsulfone

2017

Journal Article

Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide

Banerjee, Shibdas, Yang, Yun-Fang, Jenkins, Ian D., Liang, Yong, Toutov, Anton A., Liu, Wen-Bo, Schuman, David P., Grubbs, Robert H., Stoltz, Brian M., Krenske, Elizabeth H., Houk, Kendall N. and Zare, Richard N. (2017). Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide. Journal of the American Chemical Society, 139 (20), 6880-6887. doi: 10.1021/jacs.6b13032

Ionic and neutral mechanisms for C-H bond silylation of aromatic heterocycles catalyzed by potassium tert-butoxide

2017

Journal Article

Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations

Lovie-Toon, Joseph P., Tram, Camilla Mia, Flynn, Bernard L. and Krenske, Elizabeth H. (2017). Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations. Acs Catalysis, 7 (5), 3466-3476. doi: 10.1021/acscatal.7b00292

Mechanisms of carbonyl activation by BINOL N-triflylphosphoramides: enantioselective nazarov cyclizations

2017

Journal Article

Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates

Burns, Jed M., Krenske, Elizabeth H. and McGeary, Ross P. (2017). Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates. European Journal of Organic Chemistry, 2017 (2), 252-256. doi: 10.1002/ejoc.201601354

Aromatic claisen rearrangements of benzyl ketene acetals: conversion of benzylic alcohols to (ortho-tolyl)acetates

2017

Journal Article

Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols

Moore, Peter W., Hooker, Jordan P., Zavra, Athanasios, Khairallah, George N., Krenske, Elizabeth H., Bernhardt, Paul V., Quach, Gina, Moore, Evan G., O’Hair, Richard A. J. and William, Craig M. (2017). Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols. Australian Journal of Chemistry, 70 (4), 397-406. doi: 10.1071/CH16602

Hydroxyl radicals via collision-induced dissociation of trimethylammonium benzyl alcohols

2016

Journal Article

Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines

Krenske, Elizabeth H., Petter, Russell C. and Houk, K. N. (2016). Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines. Journal of Organic Chemistry, 81 (23), 11726-11733. doi: 10.1021/acs.joc.6b02188

Kinetics and thermodynamics of reversible thiol additions to mono- and diactivated Michael acceptors: implications for the design of drugs that bind covalently to cysteines

2016

Journal Article

The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations

Mohamed, Shifaza, Krenske, Elizabeth H. and Ferro, Vito (2016). The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations. Organic and Biomolecular Chemistry, 14 (10), 2950-2960. doi: 10.1039/C6OB00283H

The stereoselectivities of tributyltin hydride-mediated reductions of 5-bromo-D-glucuronides to L-iduronides are dependent on the anomeric substituent: syntheses and DFT calculations

Funding

Past funding

  • 2022 - 2025
    Opening Up Access to L-Sugars through a Synergy of Experiment and Theory
    ARC Discovery Projects
    Open grant
  • 2018 - 2022
    Computational Tools for Organic Synthesis
    ARC Discovery Projects
    Open grant
  • 2017 - 2020
    New Computational Technology to Drive Innovation in Molecular Science
    UQ Development Fellowships
    Open grant
  • 2017 - 2021
    Large area opto-electronics for Australia and India: from materials to advanced devices
    Department of Industry, Innovation, and Science - Australia-India Strategic Research Fund
    Open grant
  • 2015 - 2017
    Chiral Catalysts by Rational Design (ARC Discovery Project administered by Monash University)
    Monash University
    Open grant
  • 2014
    A parallel computer facility for modelling and simulation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2017
    Theoretical modelling and design of safe covalent anti-cancer drugs
    ARC Future Fellowships
    Open grant

Supervision

Availability

Professor Elizabeth Krenske is:
Available for supervision

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Available projects

  • Molecular modelling. Chemical Reactivity. Catalysis. Drug Design.

Supervision history

Current supervision

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Development of new computational techniques for carbohydrate and agricultural chemistry

    Principal Advisor

    Other advisors: Professor Vito Ferro

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Insight into Nonequilibrium Behaviour from Molecular Simulations

    Associate Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Synthesis of L-sugars via radical chemistry

    Associate Advisor

    Other advisors: Professor Vito Ferro

  • Doctor Philosophy

    Insight into Nonequilibrium Behaviour from Molecular Simulations

    Associate Advisor

    Other advisors: Professor Debra Bernhardt

Completed supervision

Media

Enquiries

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