![Professor Elizabeth Krenske](/sites/default/files/profiles/1018.jpeg)
Overview
Background
Professor Elizabeth Krenske leads a computational chemistry laboratory that specialises in understanding molecular behaviour. Her laboratory has a particular focus on the study of chemical reaction mechanisms, including the computational prediction of reaction outcomes. Prof. Krenske obtained her PhD in synthetic main-group chemistry at The Australian National University's Research School of Chemistry, where she worked with Professor Bruce Wild. After two years of postdoctoral research at the ANU she was awarded a Fulbright Postdoctoral Scholarship and spent two years at the University of California, Los Angeles, working in the field of theoretical and computational chemistry with Professor Kendall Houk. She returned to Australia in 2009 as an ARC Australian Postdoctoral Fellow at the University of Melbourne, and moved to The University of Queensland in 2012 as an ARC Future Fellow. She is currently a Professor in the UQ School of Chemistry and Molecular Biosciences.
Prof. Krenske is a Fellow of the Royal Australian Chemical Institute, Fellow of the Royal Society of Chemistry, Fellow of the Higher Education Academy and former Associate Editor of the RSC journal Organic & Biomolecular Chemistry.
Availability
- Professor Elizabeth Krenske is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Doctor of Philosophy, Australian National University
Works
Search Professor Elizabeth Krenske’s works on UQ eSpace
2015
Journal Article
AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates
Wang, Xiao-Na, Krenske, Elizabeth H., Johnston, Ryne C., Houk, K. N. and Hsung, Richard P. (2015). AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates. Journal of the American Chemical Society, 137 (16), 5596-5601. doi: 10.1021/jacs.5b02561
2014
Journal Article
Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.
Krenske, Elizabeth H., Houk, K. N. and Harmata, Michael (2014). Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.. Journal of Organic Chemistry, 80 (2), 744-750. doi: 10.1021/jo501906m
2014
Journal Article
Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning
Coyle, Emma E., Doonan, Bryan J., Holohan, Andrew J., Walsh, Killian A., Lavigne, Florie, Krenske, Elizabeth H. and O'Brien, Christopher J. (2014). Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning. Angewandte Chemie International Edition, 53 (47), 12907-12911. doi: 10.1002/anie.201406103
2014
Journal Article
Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324
Maslovskaya, Lidiya A., Savchenko, Andrei I., Krenske, Elizabeth H., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G. and Williams, Craig M. (2014). Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324. Chemical Communications, 50 (82), 12315-12317. doi: 10.1039/C4CC05413J
2014
Journal Article
Torquoselective ring opening of fused cyclobutenamides: Evidence for a cis,trans -cyclooctadienone intermediate
Wang, Xiao-Na, Krenske, Elizabeth H., Johnston, Ryne C., Houk, K. N. and Hsung, Richard P. (2014). Torquoselective ring opening of fused cyclobutenamides: Evidence for a cis,trans -cyclooctadienone intermediate. Journal of the American Chemical Society, 136 (28), 9802-9805. doi: 10.1021/ja502252t
2014
Journal Article
EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond
Maslovskaya, Lidiya A., Savchenko, Andrei I., Krenske, Elizabeth H., Pierce, Carly J., Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G. and Williams, Craig M. (2014). EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond. Angewandte Chemie - International Edition, 53 (27), 7006-7009. doi: 10.1002/anie.201310923
2014
Journal Article
Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of Type I sulfatase inactivation by aryl sulfamates
Williams, Spencer J., Denehy, Emma and Krenske, Elizabeth H. (2014). Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of Type I sulfatase inactivation by aryl sulfamates. The Journal of Organic Chemistry, 79 (5), 1995-2005. doi: 10.1021/jo4026513
2014
Journal Article
Nonstabilised azomethine ylids from n-oxides: unravelling the deprotonation of n-methylmorpholine n-oxide
Mirzayans, Paul Malek, Krenske, Elizabeth H. and Williams, Craig M. (2014). Nonstabilised azomethine ylids from n-oxides: unravelling the deprotonation of n-methylmorpholine n-oxide. Australian Journal of Chemistry, 67 (8-9), 1309-1317. doi: 10.1071/CH14217
2013
Journal Article
Modular mesoionics: understanding and controlling regioselectivity in 1,3-dipolar cycloadditions of Münchnone derivatives
Morin, Marie S. T., St-Cyr, Daniel J., Arndtsen, Bruce A., Krenske, Elizabeth H. and Houk, K. N. (2013). Modular mesoionics: understanding and controlling regioselectivity in 1,3-dipolar cycloadditions of Münchnone derivatives. Journal of the American Chemical Society, 135 (46), 17349-17358. doi: 10.1021/ja406833q
2013
Journal Article
Does nature click? Theoretical prediction of an enzyme-catalyzed transannular 1,3-dipolar cycloaddition in the biosynthesis of lycojaponicumins A and B
Krenske, Elizabeth H., Patel, Ashay and Houk, K. N. (2013). Does nature click? Theoretical prediction of an enzyme-catalyzed transannular 1,3-dipolar cycloaddition in the biosynthesis of lycojaponicumins A and B. Journal of the American Chemical Society, Articles ASAP (46), A-E. doi: 10.1021/ja409928z
2013
Journal Article
Aromatic interactions in asymmetric catalysis: control of enantioselectivity in Diels-Alder reactions catalysed by camphor-derived hydrazides
Krenske, Elizabeth H. (2013). Aromatic interactions in asymmetric catalysis: control of enantioselectivity in Diels-Alder reactions catalysed by camphor-derived hydrazides. Organic and Biomolecular Chemistry, 11 (32), 5226-5232. doi: 10.1039/c3ob40850g
2013
Journal Article
Opposing auxiliary conformations produce the same torquoselectivity in an oxazolidinone-directed Nazarov cyclization
Flynn, Bernard L., Manchala, Narasimhulu and Krenske, Elizabeth H. (2013). Opposing auxiliary conformations produce the same torquoselectivity in an oxazolidinone-directed Nazarov cyclization. Journal of the American Chemical Society, 135 (24), 9156-9163. doi: 10.1021/ja4036434
2013
Journal Article
Aromatic interactions as control elements in stereoselective organic reactions
Krenske, Elizabeth H. and Houk, K. N. (2013). Aromatic interactions as control elements in stereoselective organic reactions. Accounts of Chemical Research, 46 (4), 979-989. doi: 10.1021/ar3000794
2013
Journal Article
Intramolecular oxyallyl-carbonyl (3 + 2) cycloadditions
Krenske, Elizabeth H., He, Shuzhong, Huang, Jian, Du, Yunfei, Houk, K. N. and Hsung, Richard P. (2013). Intramolecular oxyallyl-carbonyl (3 + 2) cycloadditions. Journal of the American Chemical Society, 135 (14), 5242-5245. doi: 10.1021/ja312459b
2013
Journal Article
Influence of base and structure in the reversible covalent conjugate addition of thiol to polycyclic enone scaffolds
Rosenker, Christopher J., Krenske, Elizabeth H., Houk, K. N. and Wipf, Peter (2013). Influence of base and structure in the reversible covalent conjugate addition of thiol to polycyclic enone scaffolds. Organic Letters, 15 (5), 1076-1079. doi: 10.1021/ol400094k
2013
Journal Article
Control of regioselectivity and stereoselectivity in (4 + 3) cycloadditions of chiral oxyallyls with unsymmetrically disubstituted furans
Du, Yunfei, Krenske, Elizabeth H., Antoline, Jennifer E., Lohse, Andrew G., Houk, K. N. and Hsung, Richard P. (2013). Control of regioselectivity and stereoselectivity in (4 + 3) cycloadditions of chiral oxyallyls with unsymmetrically disubstituted furans. Journal of Organic Chemistry, 78 (5), 1753-1759. doi: 10.1021/jo3011792
2013
Conference Publication
Control of torquoselectivity and regioselectivity in the Nazarov cyclization by chiral oxazolidinone auxiliaries
Krenske, Elizabeth H. and Flynn, Bernard L. (2013). Control of torquoselectivity and regioselectivity in the Nazarov cyclization by chiral oxazolidinone auxiliaries. 245th National Spring Meeting of the American-Chemical-Society (ACS), New Orleans La, 7 - 11 April 2013. Washington, DC United States: American Chemical Society.
2012
Journal Article
Synthetic studies towards the mulberry Diels-Alder adducts: H-bond accelerated cycloadditions of chalcones
Boonsri, Sompong, Gunawan, Christian, Krenske, Elizabeth H. and Rizzacasa, Mark A. (2012). Synthetic studies towards the mulberry Diels-Alder adducts: H-bond accelerated cycloadditions of chalcones. Organic and Biomolecular Chemistry, 10 (30), 6010-6021. doi: 10.1039/c2ob25115a
2012
Journal Article
Causation in a cascade: the origins of selectivities in intramolecular nitrone cycloadditions
Krenske, Elizabeth H., Agopcan, Sesil, Ayiyente, Viktorya, Houk, K. N., Johnson, Brian A. and Holmes, Andrew B. (2012). Causation in a cascade: the origins of selectivities in intramolecular nitrone cycloadditions. Journal of the American Chemical Society, 134 (29), 12010-12015. doi: 10.1021/ja300002k
2012
Journal Article
Why a proximity-induced Diels-Alder reaction is so fast
Krenske, Elizabeth H., Perry, Emma W., Jerome, Steven V., Maimone, Thomas J., Baran, Phil S. and Houk, K. N. (2012). Why a proximity-induced Diels-Alder reaction is so fast. Organic Letters, 14 (12), 3016-3019. doi: 10.1021/ol301083q
Funding
Current funding
Past funding
Supervision
Availability
- Professor Elizabeth Krenske is:
- Available for supervision
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Available projects
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Molecular modelling. Chemical Reactivity. Catalysis. Drug Design.
Supervision history
Current supervision
-
Doctor Philosophy
Development of new computational techniques for carbohydrate and agricultural chemistry
Principal Advisor
Other advisors: Professor Vito Ferro
-
Doctor Philosophy
New technology for computational prediction of chemical reaction outcomes
Principal Advisor
Other advisors: Professor Debra Bernhardt
-
Doctor Philosophy
Insight into Nonequilibrium Behaviour from Molecular Simulations
Associate Advisor
Other advisors: Professor Debra Bernhardt
-
Doctor Philosophy
Synthesis of L-sugars via radical chemistry
Associate Advisor
Other advisors: Professor Vito Ferro
Completed supervision
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2024
Doctor Philosophy
Theoretical and experimental investigations into the mechanisms of Cytochromes P450
Principal Advisor
Other advisors: Professor James De Voss
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2022
Doctor Philosophy
Application of Molecular Modelling Techniques to Guide the Design of New Molecules in Material Science and Drug Discovery
Principal Advisor
Other advisors: Associate Professor Shih-Chun Lo, Associate Professor Ebinazar Namdas
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2021
Doctor Philosophy
Computational studies of asymmetric catalytic reactions
Principal Advisor
Other advisors: Professor Debra Bernhardt
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2023
Doctor Philosophy
A Synergistic Approach to L-Hexose Synthesis
Associate Advisor
Other advisors: Professor Vito Ferro
-
2017
Doctor Philosophy
Cubane in Drug Discovery and Development
Associate Advisor
Other advisors: Professor Craig Williams
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2017
Doctor Philosophy
Explorations in Novel Caged Hydrocarbon Chemistry
Associate Advisor
Other advisors: Professor Craig Williams
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2017
Doctor Philosophy
Kinetic, mechanistic, structural and spectroscopic investigations of Bimetallic Metallohydrolases.
Associate Advisor
Other advisors: Professor Gary Schenk
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2016
Doctor Philosophy
Experimental and Computational Investigations into the Benzyl-Claisen Rearrangement
Associate Advisor
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