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Professor Elizabeth Krenske
Professor

Elizabeth Krenske

Email: 
Phone: 
+61 7 336 54632

Overview

Background

Professor Elizabeth Krenske leads a computational chemistry laboratory that specialises in understanding molecular behaviour. Her laboratory has a particular focus on the study of chemical reaction mechanisms, including the computational prediction of reaction outcomes. Prof. Krenske obtained her PhD in synthetic main-group chemistry at The Australian National University's Research School of Chemistry, where she worked with Professor Bruce Wild. After two years of postdoctoral research at the ANU she was awarded a Fulbright Postdoctoral Scholarship and spent two years at the University of California, Los Angeles, working in the field of theoretical and computational chemistry with Professor Kendall Houk. She returned to Australia in 2009 as an ARC Australian Postdoctoral Fellow at the University of Melbourne, and moved to The University of Queensland in 2012 as an ARC Future Fellow. She is currently a Professor in the UQ School of Chemistry and Molecular Biosciences.

Prof. Krenske is a Fellow of the Royal Australian Chemical Institute, Fellow of the Royal Society of Chemistry, Fellow of the Higher Education Academy and former Associate Editor of the RSC journal Organic & Biomolecular Chemistry.

Availability

Professor Elizabeth Krenske is:
Available for supervision

Qualifications

  • Bachelor of Science, The University of Queensland
  • Doctor of Philosophy, Australian National University

Works

Search Professor Elizabeth Krenske’s works on UQ eSpace

138 works between 2002 and 2024

81 - 100 of 138 works

2016

Journal Article

Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation

Stok, Jeanette E., Chow, Sharon, Krenske, Elizabeth H., Farfan Soto, Clementina, Matyas, Csongor, Poirier, Raymond A., Williams, Craig M. and De Voss, James J. (2016). Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation. Chemistry: A European Journal, 22 (13), 4408-4412. doi: 10.1002/chem.201600246

Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation

2016

Journal Article

Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases

Brown, Joshua J., Gahan, Lawrence R., Schöffler, Anne, Krenske, Elizabeth H. and Schenk, Gerhard (2016). Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases. Journal of Inorganic Biochemistry, 162, 356-365. doi: 10.1016/j.jinorgbio.2016.02.008

Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases

2016

Other Outputs

Olefin strain energy as a predictor of isolability

Krenske, Elizabeth H. and Williams, Craig M. (2016). Olefin strain energy as a predictor of isolability. The University of Queensland. (Dataset) doi: 10.14264/uql.2016.208

Olefin strain energy as a predictor of isolability

2015

Journal Article

Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides

Cameron, Alex, Fisher, Brendan, Fisk, Nicholas, Hummel, Jessica, White, Jonathan M., Krenske, Elizabeth H. and Rizzacasa, Mark A. (2015). Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides. Organic Letters, 17 (24), 5998-6001. doi: 10.1021/acs.orglett.5b02965

Towards the synthesis of dihydrooxepino[4,3-b]pyrrole-containing natural products via cope rearrangement of vinyl pyrrole epoxides

2015

Journal Article

Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability

Krenske, Elizabeth H. and Williams, Craig M. (2015). Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability. Angewandte Chemie International Edition, 54 (36), 10608-10612. doi: 10.1002/anie.201503822

Do anti-Bredt natural products exist? Olefin strain energy as a predictor of isolability

2015

Journal Article

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

Challinor, Victoria L., Johnston, Ryne C., Bernhardt, Paul V., Lehmann, Reginald P., Krenske, Elizabeth H. and De Voss, James J. (2015). Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa. Chemical Science, 6 (10), 5740-5745. doi: 10.1039/c5sc02056e

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

2015

Journal Article

Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata

White, Andrew M., Pierens, Gregory K., Skinner-Adams, Tina, Andrews, Katherine T., Bernhardt, Paul V., Krenske, Elizabeth H., Mollo, Ernesto and Garson, Mary J. (2015). Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata. Journal of Natural Products, 78 (6), 1422-1427. doi: 10.1021/acs.jnatprod.5b00354

Antimalarial isocyano and isothiocyanato sesquiterpenes with tri- and bicyclic skeletons from the nudibranch Phyllidia ocellata

2015

Journal Article

Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes

Krenske, Elizabeth H., Lam, Sarah, Ng, Jerome P. L., Lo, Brian, Lam, Sze Kui, Chiu, Pauline and Houk, Kendall N. (2015). Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes. Angewandte Chemie (International Edition), 54 (25), 7422-7425. doi: 10.1002/anie.201503003

Concerted ring opening and cycloaddition of chiral epoxy enolsilanes with dienes

2015

Journal Article

Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

Volpe, Rohan, Aurelio, Luigi, Gillin, Murray G., Krenske, Elizabeth H. and Flynn, Bernard L. (2015). Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations. Chemistry - A European Journal, 21 (28), 10191-10199. doi: 10.1002/chem.201500384

Mapping the Interactions of I2, I., I−, and I+ with Alkynes and Their Roles in Iodocyclizations

2015

Journal Article

AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates

Wang, Xiao-Na, Krenske, Elizabeth H., Johnston, Ryne C., Houk, K. N. and Hsung, Richard P. (2015). AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates. Journal of the American Chemical Society, 137 (16), 5596-5601. doi: 10.1021/jacs.5b02561

AlCl3-catalyzed ring expansion cascades of bicyclic cyclobutenamides involving highly strained cis,trans-cycloheptadienone intermediates

2014

Journal Article

Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.

Krenske, Elizabeth H., Houk, K. N. and Harmata, Michael (2014). Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.. Journal of Organic Chemistry, 80 (2), 744-750. doi: 10.1021/jo501906m

Computational Analysis of the Stereochemical Outcome in the Imidazolidinone-Catalyzed Enantioselective (4 + 3)-Cycloaddition Reaction.

2014

Journal Article

Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning

Coyle, Emma E., Doonan, Bryan J., Holohan, Andrew J., Walsh, Killian A., Lavigne, Florie, Krenske, Elizabeth H. and O'Brien, Christopher J. (2014). Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning. Angewandte Chemie International Edition, 53 (47), 12907-12911. doi: 10.1002/anie.201406103

Catalytic wittig reactions of semi- and nonstabilized ylides enabled by ylide tuning

2014

Journal Article

Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324

Maslovskaya, Lidiya A., Savchenko, Andrei I., Krenske, Elizabeth H., Gordon, Victoria A., Reddell, Paul W., Pierce, Carly J., Parsons, Peter G. and Williams, Craig M. (2014). Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324. Chemical Communications, 50 (82), 12315-12317. doi: 10.1039/C4CC05413J

Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324

2014

Journal Article

Torquoselective ring opening of fused cyclobutenamides: Evidence for a cis,trans -cyclooctadienone intermediate

Wang, Xiao-Na, Krenske, Elizabeth H., Johnston, Ryne C., Houk, K. N. and Hsung, Richard P. (2014). Torquoselective ring opening of fused cyclobutenamides: Evidence for a cis,trans -cyclooctadienone intermediate. Journal of the American Chemical Society, 136 (28), 9802-9805. doi: 10.1021/ja502252t

Torquoselective ring opening of fused cyclobutenamides: Evidence for a cis,trans -cyclooctadienone intermediate

2014

Journal Article

EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond

Maslovskaya, Lidiya A., Savchenko, Andrei I., Krenske, Elizabeth H., Pierce, Carly J., Gordon, Victoria A., Reddell, Paul W., Parsons, Peter G. and Williams, Craig M. (2014). EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond. Angewandte Chemie - International Edition, 53 (27), 7006-7009. doi: 10.1002/anie.201310923

EBC-219: A new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond

2014

Journal Article

Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of Type I sulfatase inactivation by aryl sulfamates

Williams, Spencer J., Denehy, Emma and Krenske, Elizabeth H. (2014). Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of Type I sulfatase inactivation by aryl sulfamates. The Journal of Organic Chemistry, 79 (5), 1995-2005. doi: 10.1021/jo4026513

Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of Type I sulfatase inactivation by aryl sulfamates

2014

Journal Article

Nonstabilised azomethine ylids from n-oxides: unravelling the deprotonation of n-methylmorpholine n-oxide

Mirzayans, Paul Malek, Krenske, Elizabeth H. and Williams, Craig M. (2014). Nonstabilised azomethine ylids from n-oxides: unravelling the deprotonation of n-methylmorpholine n-oxide. Australian Journal of Chemistry, 67 (8-9), 1309-1317. doi: 10.1071/CH14217

Nonstabilised azomethine ylids from n-oxides: unravelling the deprotonation of n-methylmorpholine n-oxide

2013

Journal Article

Modular mesoionics: understanding and controlling regioselectivity in 1,3-dipolar cycloadditions of Münchnone derivatives

Morin, Marie S. T., St-Cyr, Daniel J., Arndtsen, Bruce A., Krenske, Elizabeth H. and Houk, K. N. (2013). Modular mesoionics: understanding and controlling regioselectivity in 1,3-dipolar cycloadditions of Münchnone derivatives. Journal of the American Chemical Society, 135 (46), 17349-17358. doi: 10.1021/ja406833q

Modular mesoionics: understanding and controlling regioselectivity in 1,3-dipolar cycloadditions of Münchnone derivatives

2013

Journal Article

Does nature click? Theoretical prediction of an enzyme-catalyzed transannular 1,3-dipolar cycloaddition in the biosynthesis of lycojaponicumins A and B

Krenske, Elizabeth H., Patel, Ashay and Houk, K. N. (2013). Does nature click? Theoretical prediction of an enzyme-catalyzed transannular 1,3-dipolar cycloaddition in the biosynthesis of lycojaponicumins A and B. Journal of the American Chemical Society, Articles ASAP (46), A-E. doi: 10.1021/ja409928z

Does nature click? Theoretical prediction of an enzyme-catalyzed transannular 1,3-dipolar cycloaddition in the biosynthesis of lycojaponicumins A and B

2013

Journal Article

Aromatic interactions in asymmetric catalysis: control of enantioselectivity in Diels-Alder reactions catalysed by camphor-derived hydrazides

Krenske, Elizabeth H. (2013). Aromatic interactions in asymmetric catalysis: control of enantioselectivity in Diels-Alder reactions catalysed by camphor-derived hydrazides. Organic and Biomolecular Chemistry, 11 (32), 5226-5232. doi: 10.1039/c3ob40850g

Aromatic interactions in asymmetric catalysis: control of enantioselectivity in Diels-Alder reactions catalysed by camphor-derived hydrazides

Funding

Past funding

  • 2022 - 2025
    Opening Up Access to L-Sugars through a Synergy of Experiment and Theory
    ARC Discovery Projects
    Open grant
  • 2018 - 2022
    Computational Tools for Organic Synthesis
    ARC Discovery Projects
    Open grant
  • 2017 - 2020
    New Computational Technology to Drive Innovation in Molecular Science
    UQ Development Fellowships
    Open grant
  • 2017 - 2021
    Large area opto-electronics for Australia and India: from materials to advanced devices
    Department of Industry, Innovation, and Science - Australia-India Strategic Research Fund
    Open grant
  • 2015 - 2017
    Chiral Catalysts by Rational Design (ARC Discovery Project administered by Monash University)
    Monash University
    Open grant
  • 2014
    A parallel computer facility for modelling and simulation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2017
    Theoretical modelling and design of safe covalent anti-cancer drugs
    ARC Future Fellowships
    Open grant

Supervision

Availability

Professor Elizabeth Krenske is:
Available for supervision

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Available projects

  • Molecular modelling. Chemical Reactivity. Catalysis. Drug Design.

Supervision history

Current supervision

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Development of new computational techniques for carbohydrate and agricultural chemistry

    Principal Advisor

    Other advisors: Professor Vito Ferro

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    New technology for computational prediction of chemical reaction outcomes

    Principal Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Synthesis of L-sugars via radical chemistry

    Associate Advisor

    Other advisors: Professor Vito Ferro

  • Doctor Philosophy

    Insight into Nonequilibrium Behaviour from Molecular Simulations

    Associate Advisor

    Other advisors: Professor Debra Bernhardt

  • Doctor Philosophy

    Insight into Nonequilibrium Behaviour from Molecular Simulations

    Associate Advisor

    Other advisors: Professor Debra Bernhardt

Completed supervision

Media

Enquiries

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