![Associate Professor Fatima Nasrallah](/sites/default/files/profiles/13561.png)
Overview
Background
Dr. Nasrallah is a neuroscientist with a background in magnetic resonance and interdisciplinary brain research. She graduated with a PhD in neurochemistry and NMR from the Neuroscience Research Australia Institute (NeurRA) at the University of New South Wales in 2009. In April 2009, She spent 3 years at the Singapore Bioimaging Consortium (A*STAR) where she pioneered the use of magnetic resonance imaging as a tool in cognitive brain research in the rodent. In 2013, she was appointed as senior research fellow at the Clinical Imaging Research Center where she delved into the clinical realms of human imaging. In late 2015, she returned to Australia as a Motor Accident and Injury Commission fellow at the Queensland Brain Institute (QBI) at the University of Queensland (UQ) where she independently heads her own group. Her research spans basic and clinical brain research with the the overall aim of understanding how the brain functions in health and injury, specifically, developing methods for early diagnosis of primary biomarkers following injury and translating these findings.
Availability
- Associate Professor Fatima Nasrallah is:
- Available for supervision
Qualifications
- Doctor of Philosophy, University of New South Wales
Research interests
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Traumatic Brain Injury
The development of translational imaging methods for the early diagnosis of brain function and prediction of patient outcome.
Research impacts
Through her work, she has established herself as one of the world experts in the area of functional brain imaging in rodent models. Her most significant contribution was made in 2014 when she demonstrated for the first time, imaging resting state functional connectivity in the mouse brain using MRI. This has made a major impact to the field especially the potential to translate such a technique in human to mouse models. This work was published in the prestigious Neuroimage journal. More impactful was the discovery that these resting state networks could detect cognition in the rat brain after a spatial learning memory task, which was also published in Neuroimage. A major contribution to the field is applying these MRI methods for clinical applications of injury and stroke. She is now leading a nationwide multicenter trial in patients with traumatic brain injury with the hope of using advanced neuroimaging methods to improve patient outcomes.
Works
Search Professor Fatima Nasrallah’s works on UQ eSpace
2016
Journal Article
Resting state functional connectivity data supports detection of cognition in the rodent brain
Nasrallah, Fatima A., To, Xuan Vinh, Chen, Der-Yow, Routtenberg, Aryeh and Chuang, Kai-Hsiang (2016). Resting state functional connectivity data supports detection of cognition in the rodent brain. Data in Brief, 7, 1156-1164. doi: 10.1016/j.dib.2016.03.041
2016
Journal Article
Characterisation and evaluation of soft elastomeric actuators for hand assistive and rehabilitation applications
Yap, Hong Kai, Lim, Jeong Hoon, Nasrallah, Fatima, Cho Hong Goh, James and Yeow, Chen-Hua (2016). Characterisation and evaluation of soft elastomeric actuators for hand assistive and rehabilitation applications. Journal of Medical Engineering and Technology, 40 (4), 199-209. doi: 10.3109/03091902.2016.1161853
2016
Journal Article
Functional connectivity MRI tracks memory networks after maze learning in rodents
Nasrallah, Fatima A., To, Xuan Vinh, Chen, Der-Yow, Routtenberg, Aryeh and Chuang, Kai-Hsiang (2016). Functional connectivity MRI tracks memory networks after maze learning in rodents. NeuroImage, 127, 196-202. doi: 10.1016/j.neuroimage.2015.08.013
2015
Journal Article
Metabolomic approaches to defining the role(s) of GABAρ receptors in the brain
Rae, Caroline, Nasrallah, Fatima A., Balcar, Vladimir J., Rowlands, Benjamin D., Johnston, Graham A. R. and Hanrahan, Jane R. (2015). Metabolomic approaches to defining the role(s) of GABAρ receptors in the brain. Journal of Neuroimmune Pharmacology, 10 (3), 445-456. doi: 10.1007/s11481-014-9579-4
2015
Journal Article
Dependence of BOLD signal fluctuation on arterial blood CO2 and O2: Implication for resting-state functional connectivity
Nasrallah, Fatima A., Yeow, Ling Yun, Biswal, Bharat and Chuang, Kai-Hsiang (2015). Dependence of BOLD signal fluctuation on arterial blood CO2 and O2: Implication for resting-state functional connectivity. NeuroImage, 117, 29-39. doi: 10.1016/j.neuroimage.2015.05.035
2015
Journal Article
Pharmacokinetics of Gd(DO3A-Lys) and MR imaging studies in an orthotopic U87MG glioma tumor model
Chandrasekharan, Prashant, Yang, Chang-Tong, Nasrallah, Fatima Ali, Tay, Hui Chien, Chuang, Kai-Hsiang and Robins, Edward G. (2015). Pharmacokinetics of Gd(DO3A-Lys) and MR imaging studies in an orthotopic U87MG glioma tumor model. Contrast Media and Molecular Imaging, 10 (3), 237-244. doi: 10.1002/cmmi.1634
2015
Conference Publication
Combining EPI and motion correction for fMRI human brain images with big motion
Lu, Zhongkang, Phua, Kok Soon, Huang, Weimin, Hong, Xin, Nasrallah, Fatima Ali, Chuang, Kai-Hsiang and Guan, Cuntai (2015). Combining EPI and motion correction for fMRI human brain images with big motion. 3Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Milan, Italy, 25-29 August 2015. Piscataway, NJ, United States: IEEE. doi: 10.1109/EMBC.2015.7319624
2015
Conference Publication
MRC-glove: A fMRI compatible soft robotic glove for hand rehabilitation application
Yap, Hong Kai, Lim, Jeong Hoon, Nasrallah, Fatima, Low, Fan-Zhe, Goh, James C.H. and Yeow, Raye C.H. (2015). MRC-glove: A fMRI compatible soft robotic glove for hand rehabilitation application. IEEE Computer Society. doi: 10.1109/ICORR.2015.7281289
2015
Conference Publication
A soft exoskeleton for hand assistive and rehabilitation application using pneumatic actuators with variable stiffness
Yap, Hong Kai, Lim, Jeong Hoon, Nasrallah, Fatima, Goh, James C. H. and Yeow, Raye C. H. (2015). A soft exoskeleton for hand assistive and rehabilitation application using pneumatic actuators with variable stiffness. 2015 IEEE International Conference on Robotics and Automation (ICRA, Seattle, WA USA, 26-30 May 2015. Washington, DC USA: IEEE Computer Society. doi: 10.1109/ICRA.2015.7139889
2014
Journal Article
Pharmacological insight into neurotransmission origins of resting-state functional connectivity: α2-adrenergic agonist vs antagonist
Nasrallah, Fatima A., Low, Si-Min, Lew, Si Kang, Chen, Kaina and Chuang, Kai-Hsiang (2014). Pharmacological insight into neurotransmission origins of resting-state functional connectivity: α2-adrenergic agonist vs antagonist. NeuroImage, 103, 364-373. doi: 10.1016/j.neuroimage.2014.09.004
2014
Journal Article
Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations
Rae, Caroline D., Davidson, Joanne E., Maher, Anthony D., Rowlands, Benjamin D., Kashem, Mohammed A., Nasrallah, Fatima A., Rallapalli, Sundari K., Cook, James M. and Balcar, Vladimir J. (2014). Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations. Journal of Neurochemistry, 129 (2), 304-314. doi: 10.1111/jnc.12634
2014
Journal Article
Detection of functional connectivity in the resting mouse brain
Nasrallah, Fatima A., Tay, Hui-Chien and Chuang, Kai-Hsiang (2014). Detection of functional connectivity in the resting mouse brain. NeuroImage, 86, 417-424. doi: 10.1016/j.neuroimage.2013.10.025
2014
Journal Article
Neural correlate of resting-state functional connectivity under α2 adrenergic receptor agonist, medetomidine
Nasrallah, Fatima A., Lew, Si Kang, Low, Amanda Si-Min and Chuang, Kai-Hsiang (2014). Neural correlate of resting-state functional connectivity under α2 adrenergic receptor agonist, medetomidine. NeuroImage, 84, 27-34. doi: 10.1016/j.neuroimage.2013.08.004
2013
Journal Article
Imaging brain deoxyglucose uptake and metabolism by glucoCEST MRI
Nasrallah, Fatima A., Pages, Guilhem, Kuchel, Philip W., Golay, Xavier and Chuang, Kai-Hsiang (2013). Imaging brain deoxyglucose uptake and metabolism by glucoCEST MRI. Journal of Cerebral Blood Flow and Metabolism, 33 (8), 1270-1278. doi: 10.1038/jcbfm.2013.79
2012
Journal Article
Optimization of flow-sensitive alternating inversion recovery (FAIR) for perfusion functional MRI of rodent brain
Nasrallah, Fatima A., Lee, Eugene L. Q. and Chuang, Kai-Hsiang (2012). Optimization of flow-sensitive alternating inversion recovery (FAIR) for perfusion functional MRI of rodent brain. NMR in Biomedicine, 25 (11), 1209-1216. doi: 10.1002/nbm.2790
2012
Journal Article
Metabolism, compartmentation, transport and production of acetate in the cortical brain tissue slice
Rae, Caroline, Fekete, Aurelie D., Kashem, Mohammed A., Nasrallah, Fatima A. and Broeer, Stefan (2012). Metabolism, compartmentation, transport and production of acetate in the cortical brain tissue slice. Neurochemical Research, 37 (11), 2541-2553. doi: 10.1007/s11064-012-0847-5
2012
Journal Article
Pharmacological modulation of functional connectivity: α2-adrenergic receptor agonist alters synchrony but not neural activation
Nasrallah, Fatima A., Tan, Jolena and Chuang, Kai-Hsiang (2012). Pharmacological modulation of functional connectivity: α2-adrenergic receptor agonist alters synchrony but not neural activation. NeuroImage, 60 (1), 436-446. doi: 10.1016/j.neuroimage.2011.12.026
2012
Book Chapter
Functional MRI of neural plasticity and drug effect in the brain
Chuang, Kai-Hsiang and Nasrallah, Fatima A. (2012). Functional MRI of neural plasticity and drug effect in the brain. Advances in bio-imaging: from physics to signal understanding issues. (pp. 17-25) edited by Nicolas Loménie, Daniel Racoceanu and Alexandre Gouaillard. Berlin, Germany: Springer-Verlag Berlin Heidelberg. doi: 10.1007/978-3-642-25547-2_2
2011
Journal Article
Activity-dependent γ-aminobutyric acid release controls brain cortical tissue slice metabolism
Nasrallah, Fatima A. , Balcar, Vladimir J. and Rae, Caroline D. (2011). Activity-dependent γ-aminobutyric acid release controls brain cortical tissue slice metabolism. Journal of Neuroscience Research, 89 (12), 1935-1945. doi: 10.1002/jnr.22649
2010
Journal Article
A metabonomic study of inhibition of GABA uptake in the cerebral cortex
Nasrallah, Fatima A., Balcar, Vladimir J. and Rae, Caroline (2010). A metabonomic study of inhibition of GABA uptake in the cerebral cortex. Metabolomics, 6 (1), 67-77. doi: 10.1007/s11306-009-0176-0
Funding
Current funding
Supervision
Availability
- Associate Professor Fatima Nasrallah is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Structural and Functional changes in aged hippocampus following exercise as detected by MRI
Principal Advisor
-
Doctor Philosophy
Investigating therapeutic interventions following concussion
Principal Advisor
Other advisors: Professor Karen Barlow
-
Doctor Philosophy
Development of a model for prognostication of patient outcome following traumatic brain injury
Principal Advisor
Other advisors: Dr Shakes Chandra
-
Doctor Philosophy
The development of precision medical care for the use of ketamine as a treatment for Australian Veterans with TRD and PTSD
Principal Advisor
Other advisors: Associate Professor Susannah Tye
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Doctor Philosophy
Development of precision medicine biomarkers for ketamine as a treatment for TRD and PTSD
Associate Advisor
Other advisors: Associate Professor Susannah Tye
Completed supervision
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2021
Doctor Philosophy
Neuroimaging of Traumatic Brain Injury and Dementia: Bridging the link
Principal Advisor
Other advisors: Professor Peter Nestor
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2021
Doctor Philosophy
Application of Magnetic Resonance methods for the in vivo imaging of a mouse model of concussion
Principal Advisor
Other advisors: Dr Viktor Vegh
-
2020
Doctor Philosophy
Magnetic Resonance Imaging reveals underlying pathology associated with traumatic brain injury in a tau transgenic mouse model
Principal Advisor
Other advisors: Associate Professor Karin Borges
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2018
Master Philosophy
Defining key structural and functional changes in the adult brain in a mouse model of depression
Associate Advisor
Other advisors: Dr Dhanisha Jhaveri
Media
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