Overview
Background
Shakes an imaging expert that leads a strong deep learning, artificial intelligence (AI) focused research team interested in medical image analysis and signal/image processing applied to many areas of science and medicine. He received his Ph.D in Theoretical Physics from Monash University, Melbourne and has been involved in applying machine learning in medical imaging for over a decade.
Shakes’ past work has involved developing shape model-based algorithms for knee, hip and shoulder joint segmentation that is being developed and deployed as a product on the Siemens syngo.via platform. More recent work involves deep learning based algorithms for semantic segmentation and manifold learning of imaging data. Broadly, he is interested in understanding and developing the mathematical basis of imaging, image analysis algorithms and physical systems. He has developed algorithms that utilise exotic mathematical structures such as fractals, turbulence, group theoretic concepts and number theory in the image processing approaches that he has developed.
He is currently a Senior Lecturer and leads a team of 20+ researchers working image analysis and AI research across healthcare and medicine. He currently teaches the computer science courses Theory of Computation and Pattern Recognition and Analysis.
Availability
- Dr Shakes Chandra is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, Monash University
Research interests
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Magnetic Resonance Imaging
Making MRI faster and more affordable through better image reconstruction, processing and analysis.
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Image Processing
Image reconstruction, segmentation and registration.
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Deep learning
Dimensionality reduction, machine learning and Artificial Intelligence
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Fractals and Chaos
Applying fractals and chaos to image processing and computer science.
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Number Theory
Applying number theory to image processing and computer science.
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Medical Image Analysis
Medical image segmentation and shape analysis
Works
Search Professor Shakes Chandra’s works on UQ eSpace
2025
Journal Article
SCGC : Self-supervised contrastive graph clustering
Kulatilleke, Gayan K., Portmann, Marius and Chandra, Shekhar S. (2025). SCGC : Self-supervised contrastive graph clustering. Neurocomputing, 611 128629, 128629. doi: 10.1016/j.neucom.2024.128629
2024
Journal Article
An automated and robust tool for musculoskeletal and finite element modeling of the knee joint
Esrafilian, Amir, Chandra, Shekhar S, Gatti, Anthony A, Nissi, Mikko, Mustonen, Anne-Mari, Saisanen, Laura, Reijonen, Jusa, Nieminen, Petteri, Julkunen, Petro, Toyras, Juha, Saxby, David J, Lloyd, David G and Korhonen, Rami K (2024). An automated and robust tool for musculoskeletal and finite element modeling of the knee joint. IEEE Transactions on Biomedical Engineering, 1-13. doi: 10.1109/tbme.2024.3438272
2024
Conference Publication
A Tiered Quadruplet Network with Patient-Specific Mining and Dynamic Margin for Improved ugly Duckling Lesion Classification
Naranpanawa, Nathasha, Soyer, H. Peter, Mothershaw, Adam, Kulatilleke, Gayan K., Ge, Zongyuan, Betz-Stablein, Brigid and Chandra, Shekhar S. (2024). A Tiered Quadruplet Network with Patient-Specific Mining and Dynamic Margin for Improved ugly Duckling Lesion Classification. IEEE. doi: 10.1109/isbi56570.2024.10635546
2024
Conference Publication
Single image compressed sensing MRI via a self-supervised deep denoising approach
Bran Lorenzana, Marlon, Liu, Feng and Chandra, Shekhar S. (2024). Single image compressed sensing MRI via a self-supervised deep denoising approach. 2024 IEEE International Symposium on Biomedical Imaging (ISBI), Athens, Greece, 27-30 May 2024. Piscataway, NJ, United States: IEEE. doi: 10.1109/isbi56570.2024.10635749
2024
Journal Article
Automated Detection of Pigmented Iris Freckles using a Deep Neural Network for Cutaneous Melanoma Risk
Naranpanawa, Nathasha, Jayasinghe, Dilki, Sturm, Richard A., Betz-Stablein, Brigid, Janda, Monika, Eriksson, Anders, Soyer, H. Peter and Chandra, Shekhar S. (2024). Automated Detection of Pigmented Iris Freckles using a Deep Neural Network for Cutaneous Melanoma Risk. Journal of Investigative Dermatology, 144 (11), 2602-2605.e4. doi: 10.1016/j.jid.2024.04.029
2024
Journal Article
Automatic segmentation of tumour and organs at risk in 3D MRI for cervical cancer radiation therapy with anatomical variations
Leung, Sze-Nung, Chandra, Shekhar S., Lim, Karen, Young, Tony, Holloway, Lois and Dowling, Jason A. (2024). Automatic segmentation of tumour and organs at risk in 3D MRI for cervical cancer radiation therapy with anatomical variations. Physical and Engineering Sciences in Medicine, 47 (3), 1-10. doi: 10.1007/s13246-024-01415-y
2024
Journal Article
Automated anomaly-aware 3D segmentation of bones and cartilages in knee MR images from the Osteoarthritis Initiative
Woo, Boyeong, Engstrom, Craig, Baresic, William, Fripp, Jurgen, Crozier, Stuart and Chandra, Shekhar S. (2024). Automated anomaly-aware 3D segmentation of bones and cartilages in knee MR images from the Osteoarthritis Initiative. Medical Image Analysis, 93 103089. doi: 10.1016/j.media.2024.103089
2024
Journal Article
Analysis of cam location characteristics in FAI syndrome patients from 3D MR images demonstrates sex‐specific differences
Bugeja, Jessica M., Xia, Ying, Chandra, Shekhar S., Murphy, Nicholas J., Crozier, Stuart, Hunter, David J., Fripp, Jurgen and Engstrom, Craig (2024). Analysis of cam location characteristics in FAI syndrome patients from 3D MR images demonstrates sex‐specific differences. Journal of Orthopaedic Research, 42 (2), 385-394. doi: 10.1002/jor.25674
2024
Journal Article
GrainPointNet: a deep-learning framework for non-invasive sorghum panicle grain count phenotyping
James, Chrisbin, Smith, Daniel, He, Weigao, Chandra, Shekhar S. and Chapman, Scott C. (2024). GrainPointNet: a deep-learning framework for non-invasive sorghum panicle grain count phenotyping. Computers and Electronics in Agriculture, 217 108485, 108485. doi: 10.1016/j.compag.2023.108485
2024
Journal Article
AliasNet: Alias artefact suppression network for accelerated phase-encode MRI
Bran Lorenzana, Marlon, Chandra, Shekhar S. and Liu, Feng (2024). AliasNet: Alias artefact suppression network for accelerated phase-encode MRI. Magnetic Resonance Imaging, 105, 17-28. doi: 10.1016/j.mri.2023.10.001
2024
Journal Article
Multi-modal traumatic brain injury prognosis via structure-aware field-wise learning
Zhang, Lu, Li, Zhibin, Chandra, Shekhar S. and Nasrallah, Fatima (2024). Multi-modal traumatic brain injury prognosis via structure-aware field-wise learning. IEEE Transactions on Knowledge and Data Engineering, 36 (8), 1-12. doi: 10.1109/tkde.2024.3364385
2024
Conference Publication
Interpretable 3D multi-modal residual convolutional neural network for mild traumatic brain injury diagnosis
Ellethy, Hanem, Vegh, Viktor and Chandra, Shekhar S. (2024). Interpretable 3D multi-modal residual convolutional neural network for mild traumatic brain injury diagnosis. 36th Australasian Joint Conference on Artificial Intelligence, AI 2023, Brisbane, QLD, Australia, 28 November – 1 December 2023. Singapore, Singapore: Springer Nature Singapore. doi: 10.1007/978-981-99-8388-9_39
2024
Other Outputs
Pigmented Iris Freckle Data
Naranpanawa, Nathasha, Chandra, Shekhar S. and Sturm, Richard A. (2024). Pigmented Iris Freckle Data . The University of Queensland. (Dataset) doi: 10.48610/355ad45
2024
Conference Publication
An unsupervised deep learning-based method for in vivo high resolution Kidney MRI motion correction
Moinian, Shahrzad, Kurniawan, Nyoman, Chandra, Shekhar, Vegh, Viktor and Reutens, David (2024). An unsupervised deep learning-based method for in vivo high resolution Kidney MRI motion correction. 2023 ISMRM & ISMRT Annual Meeting & Exhibition, Toronto, ON, Canada, 3-8 June 2023. Berkeley, CA, United States: International Society for Magnetic Resonance in Medicine. doi: 10.58530/2023/4915
2023
Journal Article
Efficient block contrastive learning via parameter-free meta-node approximation
Kulatilleke, Gayan K., Portmann, Marius and Chandra, Shekhar S. (2023). Efficient block contrastive learning via parameter-free meta-node approximation. Neurocomputing, 561 126850, 126850. doi: 10.1016/j.neucom.2023.126850
2023
Conference Publication
Manipulating medical image translation with manifold disentanglement
Liu, Siyu, Dowling, Jason A., Engstrom, Craig, Greer, Peter B., Crozier, Stuart and Chandra, Shekhar S. (2023). Manipulating medical image translation with manifold disentanglement. 2023 International Conference on Digital Image Computing: Techniques and Applications (DICTA), Port Macquarie, Australia, 28 November-1 December 2023. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/dicta60407.2023.00053
2023
Conference Publication
Suspicious naevi classification using auxiliary classifier generative adversarial network
Zegair, Fatima Al, Rutjes, Chantal, Betz-Stablein, Brigid, Ge, Zongyuan, Soyer, H. Peter and Chandra, Shekhar S. (2023). Suspicious naevi classification using auxiliary classifier generative adversarial network. 2023 International Conference on Digital Image Computing: Techniques and Applications (DICTA), Port Macquarie, NSW, Australia, 28 November - 1 December 2023. Piscataway, NJ, United States: IEEE. doi: 10.1109/dicta60407.2023.00041
2023
Conference Publication
TriFormer: A multi-modal transformer framework for mild cognitive impairment conversion prediction
Liu, Linfeng, Lyu, Junyan, Liu, Siyu, Tang, Xiaoying, Chandra, Shekhar S. and Nasrallah, Fatima A. (2023). TriFormer: A multi-modal transformer framework for mild cognitive impairment conversion prediction. 20th IEEE International Symposium on Biomedical Imaging (ISBI), Cartagena, Colombia, 18-21 April 2023. Piscataway, NJ United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/isbi53787.2023.10230709
2023
Journal Article
Non-separable two-dimensional Hadamard transform via a discrete Hadamard slice theorem
Lorenzana, Marlon Bran and Chandra, Shekhar S. (2023). Non-separable two-dimensional Hadamard transform via a discrete Hadamard slice theorem. IEEE Signal Processing Letters, 30 (99), 1237-1241. doi: 10.1109/lsp.2023.3311349
2023
Conference Publication
Medical shape pattern analysis with MeshCNN
Leung, Sze-Nung, Dowling, Jason A., Fripp, Jurgen, Shen, Kai-Kai and Chandra, Shekhar S. (2023). Medical shape pattern analysis with MeshCNN. 20th IEEE International Symposium on Biomedical Imaging (ISBI), Cartagena, Colombia, 18-21 April 2023. Piscataway, NJ United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/isbi53787.2023.10230427
Funding
Current funding
Past funding
Supervision
Availability
- Dr Shakes Chandra is:
- Available for supervision
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Available projects
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Machine learning applied to 3D magnetic resonance images
Magnetic resonance (MR) imaging has become an important non-invasive radiological modality for various clinical applications, such as cartilage assessment for Osteoarthritis and treatment planning for prostate cancer. MR images in 3D, while providing a wealth of anatomical information, including bones and soft tissue, are difficult to analyse due to the presence of a large number of complex structures. Thus, extracting meaningful clinical information without human interaction is a challenging task. Developing such automatic methods are important in order to reduce human errors and the time taken by clinicians in completing mundane tasks, such as marking or delineating 3D images by hand, from hours to just a few minutes by utilising computers.
In this project, the student will develop novel algorithms to solve segmentation and detection problems for MR imaging that could possibly be deployed to MRI scanners and may eventually used for diagnostic purposes. The project will involve applying computer vision and machine learning techniques (including deep learning) to MR image processing and analysis.
Supervision history
Current supervision
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Doctor Philosophy
Magnetic Resonance Image Processing with Artificial Intelligence
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Dr Hongfu Sun
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Doctor Philosophy
Towards Analysis of Contextual Melanoma Indicators and Identification of Total-Body Ugly Duckling Lesions with Deep Neural Networks
Principal Advisor
Other advisors: Dr Mahsa Baktashmotlagh, Dr Brigid Betz-Stablein
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Doctor Philosophy
Manifold Learning for Magnetic Resonance Imaging
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Foundational models for visual recognition
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Deep Learning Applied to Medical Image Analysis
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Deployable and Explainable Deep Learning Architectures: Navigating Clinical Challenges in Medical Image Segmentation
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Deep Learning Strategies for Enhanced mTBI Diagnosis Using Clinical and CT Data
Principal Advisor
Other advisors: Dr Viktor Vegh
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Doctor Philosophy
Automated Detection and Classification of Suspicious Naevi in Dermoscopy Images Through Artificial Intelligence
Principal Advisor
Other advisors: Professor Peter Soyer, Professor Monika Janda, Dr Brigid Betz-Stablein
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Doctor Philosophy
Medical Shape Analysis of 3D MRI Segmentation with Deep Learning
Principal Advisor
Other advisors: Emeritus Professor Stuart Crozier
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Doctor Philosophy
Improving Feature Extraction and Feature Interpretability for Deep Learning in Medical Image Analysis
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Novel deep learning approaches to understanding human diseases
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Advanced Deep Learning Approaches for Improving Diagnosis and Prognosis in Brain Disease
Associate Advisor
Other advisors: Associate Professor Fatima Nasrallah
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Doctor Philosophy
Using 3D total body imaging to study the spatial distribution of naevi and melanoma
Associate Advisor
Other advisors: Professor Peter Soyer, Professor Monika Janda
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Doctor Philosophy
Artifical intelligence approaches for diagnosing and phenotyping sleep disorders
Associate Advisor
Other advisors: Professor Juha Toyras, Associate Professor Philip Terrill
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Doctor Philosophy
New deep learning based methods for assessment of sleep apnea severity and risk of related short and long term health consequences
Associate Advisor
Other advisors: Professor Juha Toyras, Associate Professor Philip Terrill
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Doctor Philosophy
Virtual Agricultural Imaging and Sensing through Artificial Intelligence and Computer Vision
Associate Advisor
Other advisors: Professor Scott Chapman
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Doctor Philosophy
Establishment of a National Anterior Cruciate Ligament (ACL) Registry in Australia
Associate Advisor
Other advisors: Associate Professor Craig Engstrom
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Doctor Philosophy
New deep learning based methods for assessment of sleep apnea severity and risk of related short and long term health consequences
Associate Advisor
Other advisors: Professor Juha Toyras, Associate Professor Philip Terrill
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Doctor Philosophy
Development of a model for prognostication of patient outcome following traumatic brain injury
Associate Advisor
Other advisors: Associate Professor Fatima Nasrallah
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Doctor Philosophy
Machine learning methods for visualisation and quantification of nephrons with MRI.
Associate Advisor
Other advisors: Dr Nyoman Kurniawan
Completed supervision
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2024
Doctor Philosophy
Towards Analysis of Contextual Melanoma Indicators and Identification of Total-Body Ugly Duckling Lesions with Deep Neural Networks
Principal Advisor
Other advisors: Dr Mahsa Baktashmotlagh, Dr Brigid Betz-Stablein
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2024
Doctor Philosophy
Deep Learning Strategies for Enhanced mTBI Diagnosis using Clinical and CT Data
Principal Advisor
Other advisors: Dr Viktor Vegh
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2024
Doctor Philosophy
Deployable and Interpretable Deep Learning Architectures: Navigating Clinical Challenges in Medical Image Segmentation
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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2024
Doctor Philosophy
Efficient Image Representations for Compressed Sensing MRI
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Professor Feng Liu, Professor Markus Barth
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2023
Doctor Philosophy
Towards Efficient Graph Neural Networks for Optimizing Illicit Dark Web Interventions
Principal Advisor
Other advisors: Associate Professor Marius Portmann
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2022
Doctor Philosophy
Automated Assessment of Cartilage Composition and Cam Morphology using Magnetic Resonance Images of the Hip Joint
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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2020
Doctor Philosophy
Computer aided lesion detection, segmentation and characterization on mammography and breast MRI
Principal Advisor
Other advisors: Emeritus Professor Stuart Crozier
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2023
Doctor Philosophy
In vitro evaluation of porous PHBV-based scaffolds for tissue regeneration application
Associate Advisor
Other advisors: Dr Mingyuan Lu
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2022
Doctor Philosophy
Improving deep learning-based fast MRI with pre-acquired image guidance
Associate Advisor
Other advisors: Emeritus Professor Stuart Crozier, Professor Feng Liu
Media
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