Overview
Background
Shakes an imaging expert that leads a strong deep learning, artificial intelligence (AI) focused research team interested in medical image analysis and signal/image processing applied to many areas of science and medicine. He received his Ph.D in Theoretical Physics from Monash University, Melbourne and has been involved in applying machine learning in medical imaging for over a decade.
Shakes’ past work has involved developing shape model-based algorithms for knee, hip and shoulder joint segmentation that is being developed and deployed as a product on the Siemens syngo.via platform. More recent work involves deep learning based algorithms for semantic segmentation and manifold learning of imaging data. Broadly, he is interested in understanding and developing the mathematical basis of imaging, image analysis algorithms and physical systems. He has developed algorithms that utilise exotic mathematical structures such as fractals, turbulence, group theoretic concepts and number theory in the image processing approaches that he has developed.
He is currently a Senior Lecturer and leads a team of 20+ researchers working image analysis and AI research across healthcare and medicine. He currently teaches the computer science courses Theory of Computation and Pattern Recognition and Analysis.
Availability
- Dr Shakes Chandra is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, Monash University
Research interests
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Magnetic Resonance Imaging
Making MRI faster and more affordable through better image reconstruction, processing and analysis.
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Image Processing
Image reconstruction, segmentation and registration.
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Deep learning
Dimensionality reduction, machine learning and Artificial Intelligence
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Fractals and Chaos
Applying fractals and chaos to image processing and computer science.
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Number Theory
Applying number theory to image processing and computer science.
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Medical Image Analysis
Medical image segmentation and shape analysis
Works
Search Professor Shakes Chandra’s works on UQ eSpace
2022
Journal Article
CAN3D: Fast 3D medical image segmentation via compact context aggregation
Dai, Wei, Woo, Boyeong, Liu, Siyu, Marques, Matthew, Engstrom, Craig, Greer, Peter B., Crozier, Stuart, Dowling, Jason A. and Chandra, Shekhar S. (2022). CAN3D: Fast 3D medical image segmentation via compact context aggregation. Medical Image Analysis, 82 102562, 1-17. doi: 10.1016/j.media.2022.102562
2022
Journal Article
Deep neural networks predict the need for CT in pediatric mild traumatic brain injury: a corroboration of the PECARN rule
Ellethy, Hanem, Chandra, Shekhar S. and Nasrallah, Fatima A. (2022). Deep neural networks predict the need for CT in pediatric mild traumatic brain injury: a corroboration of the PECARN rule. Journal of the American College of Radiology, 19 (6), 769-778. doi: 10.1016/j.jacr.2022.02.024
2022
Journal Article
Automated 3D analysis of clinical magnetic resonance images demonstrates significant reductions in cam morphology following arthroscopic intervention in contrast to physiotherapy
Bugeja, Jessica M., Xia, Ying, Chandra, Shekhar S., Murphy, Nicholas J., Eyles, Jillian, Spiers, Libby, Crozier, Stuart, Hunter, David J., Fripp, Jurgen and Engstrom, Craig (2022). Automated 3D analysis of clinical magnetic resonance images demonstrates significant reductions in cam morphology following arthroscopic intervention in contrast to physiotherapy. Arthroscopy, Sports Medicine, and Rehabilitation, 4 (4), e1353-e1362. doi: 10.1016/j.asmr.2022.04.020
2022
Journal Article
Automated volumetric and statistical shape assessment of cam-type morphology of the femoral head-neck region from clinical 3D magnetic resonance images
Bugeja, Jessica M., Xia, Ying, Chandra, Shekhar S., Murphy, Nicholas J., Eyles, Jillian, Spiers, Libby, Crozier, Stuart, Hunter, David J., Fripp, Jurgen and Engstrom, Craig (2022). Automated volumetric and statistical shape assessment of cam-type morphology of the femoral head-neck region from clinical 3D magnetic resonance images. Quantitative Imaging in Medicine and Surgery, 12 (10), 4941. doi: 10.21037/qims-22-332
2022
Conference Publication
Anomaly-aware 3D segmentation of knee magnetic resonance images
Woo, Boyeong, Engstrom, Craig, Fripp, Jurgen, Crozier, Stuart and Chandra, Shekhar S. (2022). Anomaly-aware 3D segmentation of knee magnetic resonance images. 5th International Conference on Medical Imaging with Deep Learning, Zurich, Switzerland, 6-8 July 2022. Cambridge, MA United States: ML Research Press.
2022
Conference Publication
Undersampled MRI reconstruction with side information-guided normalisation
Liu, Xinwen, Wang, Jing, Peng, Cheng, Chandra, Shekhar S., Liu, Feng and Zhou, S. Kevin (2022). Undersampled MRI reconstruction with side information-guided normalisation. Medical Image Computing and Computer Assisted Intervention – MICCAI, Singapore, Singapore, 18-22 September 2022. Cham, Switzerland: Springer Nature Switzerland. doi: 10.1007/978-3-031-16446-0_31
2022
Conference Publication
FDGATII: Fast Dynamic Graph Attention with Initial Residual and Identity
Kulatilleke, Gayan K., Portmann, Marius, Ko, Ryan and Chandra, Shekhar S. (2022). FDGATII: Fast Dynamic Graph Attention with Initial Residual and Identity. 35th Australasian Joint Conference on Artificial Intelligence: AI 2022, Perth, WA Australia, 5–8 December 2022. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-22695-3_6
2021
Conference Publication
Slim-YOLO: a simplified object detection model for the detection of pigmented iris freckles as a potential biomarker for cutaneous melanoma
Naranpanawa, D. Nathasha U., Gu, Yanyang, Chandra, Shekhar S., Betz-Stablein, Brigid, Sturm, Richard A., Soyer, H. Peter and Eriksson, Anders P. (2021). Slim-YOLO: a simplified object detection model for the detection of pigmented iris freckles as a potential biomarker for cutaneous melanoma. Digital Image Computing: Techniques and Applications (DICTA), Gold Coast, Australia, 29 November - 1 December 2021. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/dicta52665.2021.9647150
2021
Journal Article
Automated analysis of immediate reliability of T2 and T2* relaxation times of hip joint cartilage from 3 T MR examinations
Bugeja, Jessica M., Chandra, Shekhar S., Neubert, Aleš, Fripp, Jurgen, Lockard, Carly A., Ho, Charles P., Crozier, Stuart and Engstrom, Craig (2021). Automated analysis of immediate reliability of T2 and T2* relaxation times of hip joint cartilage from 3 T MR examinations. Magnetic Resonance Imaging, 82, 42-54. doi: 10.1016/j.mri.2021.06.008
2021
Journal Article
The detection of mild traumatic brain injury in paediatrics using artificial neural networks
Ellethy, Hanem, Chandra, Shekhar S. and Nasrallah, Fatima A. (2021). The detection of mild traumatic brain injury in paediatrics using artificial neural networks. Computers in Biology and Medicine, 135 104614, 1-9. doi: 10.1016/j.compbiomed.2021.104614
2021
Journal Article
Deep learning in magnetic resonance image reconstruction
Chandra, Shekhar S., Bran Lorenzana, Marlon, Liu, Xinwen, Liu, Siyu, Bollmann, Steffen and Crozier, Stuart (2021). Deep learning in magnetic resonance image reconstruction. Journal of Medical Imaging and Radiation Oncology, 65 (5) 1754-9485.13276, 564-577. doi: 10.1111/1754-9485.13276
2021
Journal Article
Bespoke fractal sampling patterns for discrete Fourier space via the kaleidoscope transform
White, Jacob Michael, Crozier, Stuart and Chandra, Shekhar Suresh (2021). Bespoke fractal sampling patterns for discrete Fourier space via the kaleidoscope transform. IEEE Signal Processing Letters, 14 (8), 1-5. doi: 10.1109/lsp.2021.3116510
2021
Conference Publication
Can3d: Fast 3D knee mri segmentation via compact context aggregation
Dai, Wei, Woo, Boyeong, Liu, Siyu, Marques, Matthew, Tang, Fangfang, Crozier, Stuart, Engstrom, Craig and Chandra, Shekhar (2021). Can3d: Fast 3D knee mri segmentation via compact context aggregation. 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI), Nice, France, 13-16 April 2021. Piscataway, NJ United States: IEEE. doi: 10.1109/isbi48211.2021.9433784
2021
Journal Article
On the regularization of feature fusion and mapping for fast MR multi-contrast imaging via iterative networks
Liu, Xinwen, Wang, Jing, Sun, Hongfu, Chandra, Shekhar S, Crozier, Stuart and Liu, Feng (2021). On the regularization of feature fusion and mapping for fast MR multi-contrast imaging via iterative networks. Magnetic resonance imaging, 77, 159-168. doi: 10.1016/j.mri.2020.12.019
2021
Journal Article
Discrete element and finite element methods provide similar estimations for hip joint contact mechanics during walking gait
Li, Mao, Venäläinen, Mikko S., Chandra, Shekhar S., Patel, Rushabh, Fripp, Jurgen, Engstrom, Craig, Korhonen, Rami K., Töyräs, Juha and Crozier, Stuart (2021). Discrete element and finite element methods provide similar estimations for hip joint contact mechanics during walking gait. Journal of Biomechanics, 115 110163, 1-11. doi: 10.1016/j.jbiomech.2020.110163
2021
Conference Publication
End-to-end ugly duckling sign detection for melanoma identification with transformers
Yu, Zhen, Mar, Victoria, Eriksson, Anders, Chandra, Shakes, Bonnington, Paul, Zhang, Lei and Ge, Zongyuan (2021). End-to-end ugly duckling sign detection for melanoma identification with transformers. Medical Image Computing and Computer Assisted Intervention – MICCAI 2021, Strasbourg, France, 27 September-1 October 2021. Cham, Switzerland: Springer Nature Switzerland. doi: 10.1007/978-3-030-87234-2_17
2021
Journal Article
The application of statistical shape modeling for lung morphology in aerosol inhalation dosimetry
Xi, Jinxiang, Talaat, Mohamed, Si, Xiuhua April and Chandra, Shekhar (2021). The application of statistical shape modeling for lung morphology in aerosol inhalation dosimetry. Journal of Aerosol Science, 151 105623, 105623. doi: 10.1016/j.jaerosci.2020.105623
2020
Journal Article
Automatic lesion detection, segmentation and characterization via 3D multiscale morphological sifting in breast MRI
Min, Hang, McClymont, Darryl, Chandra, Shekhar S., Crozier, Stuart and Bradley, Andrew P. (2020). Automatic lesion detection, segmentation and characterization via 3D multiscale morphological sifting in breast MRI. Biomedical Physics and Engineering Express, 6 (6) 065027, 065027. doi: 10.1088/2057-1976/abc45c
2020
Journal Article
Fast geometric distortion correction using a deep neural network: implementation for the 1 Tesla MRI-Linac system
Li, Mao, Shan, Shanshan, Chandra, Shekhar S., Liu, Feng and Crozier, Stuart (2020). Fast geometric distortion correction using a deep neural network: implementation for the 1 Tesla MRI-Linac system. Medical Physics, 47 (9) mp.14382, 4303-4315. doi: 10.1002/mp.14382
2020
Conference Publication
Deep simultaneous optimization of sampling and reconstruction for multi-contrast MRI
Liu, Xinwen, Wang, Jing, Tang, Fangfang, Chandra, Shekhar S., Liu, Feng and Crozier, Stuart (2020). Deep simultaneous optimization of sampling and reconstruction for multi-contrast MRI. ISMRM & SMRT Virtual Conference & Exhibition, 2020, Online, 8-14 August 2020.
Funding
Current funding
Past funding
Supervision
Availability
- Dr Shakes Chandra is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
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Next generation magnetic resonance imaging MRI through vision
Summary: Magnetic resonance imaging (MRI) is crucial for diagnosing diseases within the human body. In this project, we develop new AI methods that leverage human visual perception to make MRI faster and more affordable.
Technologies such as magnetic resonance imaging (MRI) are essential in healthcare for non-invasively seeing inside the human body for disease diagnosis and assessment. However, imaging cost for MRI is so prohibitive that it is seldom used unless there is no other option despite its effectiveness. The cost is largely because MRI is a slow imaging modality compared to other options that do not provide as much information and soft tissue contrast needed to detect diseases such as cancer. Although some progress has been made to improve acquisition speed, all current methods do not make any allowances for the way that human experts read and understand regions of interest. A reduction in scan time will make MRI cheaper and therefore allow the technology to be more readily utilised in the future.
This project aims to create new artificial intelligence (AI) models and unify them with MRI acquisition directly in its measurement domain, helping us explain such models and create acquisitions more akin to human vision that only acquires the areas an operator needs, thereby reducing scan times.
Supervision history
Current supervision
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Doctor Philosophy
Foundational models for visual recognition
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Manifold Learning for Magnetic Resonance Imaging
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
AI in the detection and diagnosis of preclinical and early osteoarthritis
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Dr Kieran O'Brien
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Doctor Philosophy
Novel deep learning approaches to understanding human diseases
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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Doctor Philosophy
Magnetic Resonance Image Processing with Artificial Intelligence
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Dr Hongfu Sun
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Doctor Philosophy
Neonatal brain MRI of very preterm infants for prediction of neurodevelopmental outcomes
Associate Advisor
Other advisors: Dr Kerstin Pannek
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Doctor Philosophy
Artifical intelligence approaches for diagnosing and phenotyping sleep disorders
Associate Advisor
Other advisors: Professor Juha Toyras, Associate Professor Philip Terrill
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Doctor Philosophy
Using 3D total body imaging to study the spatial distribution of naevi and melanoma
Associate Advisor
Other advisors: Professor Peter Soyer, Professor Monika Janda
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Doctor Philosophy
Deep Learning Methods Towards Reliable and Physiology-Aligned Sleep Scoring
Associate Advisor
Other advisors: Professor Juha Toyras, Associate Professor Philip Terrill
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Doctor Philosophy
Establishment of a National Anterior Cruciate Ligament (ACL) Registry in Australia
Associate Advisor
Other advisors: Associate Professor Craig Engstrom
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Doctor Philosophy
Machine learning methods for visualisation and quantification of nephrons with MRI.
Associate Advisor
Other advisors: Dr Nyoman Kurniawan
Completed supervision
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2025
Doctor Philosophy
Improving Feature Extraction and Feature Interpretability for Deep Learning in Medical Image Analysis
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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2025
Doctor Philosophy
Medical Shape Analysis of 3D MRI Segmentation with Deep Learning
Principal Advisor
Other advisors: Emeritus Professor Stuart Crozier
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2025
Doctor Philosophy
Automated Detection and Classification of Suspicious Naevi in Dermoscopy Images Through Artificial Intelligence
Principal Advisor
Other advisors: Professor Peter Soyer, Professor Monika Janda
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2024
Doctor Philosophy
Deployable and Interpretable Deep Learning Architectures: Navigating Clinical Challenges in Medical Image Segmentation
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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2024
Doctor Philosophy
Towards Analysis of Contextual Melanoma Indicators and Identification of Total-Body Ugly Duckling Lesions with Deep Neural Networks
Principal Advisor
Other advisors: Associate Professor Mahsa Baktashmotlagh
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2024
Doctor Philosophy
Deep Learning Strategies for Enhanced mTBI Diagnosis using Clinical and CT Data
Principal Advisor
Other advisors: Dr Viktor Vegh
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2024
Doctor Philosophy
Efficient Image Representations for Compressed Sensing MRI
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Professor Feng Liu, Professor Markus Barth
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2023
Doctor Philosophy
Towards Efficient Graph Neural Networks for Optimizing Illicit Dark Web Interventions
Principal Advisor
Other advisors: Professor Marius Portmann
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2022
Doctor Philosophy
Automated Assessment of Cartilage Composition and Cam Morphology using Magnetic Resonance Images of the Hip Joint
Principal Advisor
Other advisors: Associate Professor Craig Engstrom, Emeritus Professor Stuart Crozier
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2020
Doctor Philosophy
Computer aided lesion detection, segmentation and characterization on mammography and breast MRI
Principal Advisor
Other advisors: Emeritus Professor Stuart Crozier
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2025
Doctor Philosophy
3D Imaging and Deep Learning for Phenotyping Sorghum at Canopy Scale
Associate Advisor
Other advisors: Professor Scott Chapman
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2025
Doctor Philosophy
Advanced Deep Learning Approaches for Improving Diagnosis and Prognosis in Brain Disease
Associate Advisor
Other advisors: Associate Professor Fatima Nasrallah
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2023
Doctor Philosophy
In vitro evaluation of porous PHBV-based scaffolds for tissue regeneration application
Associate Advisor
Other advisors: Dr Mingyuan Lu
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2022
Doctor Philosophy
Improving deep learning-based fast MRI with pre-acquired image guidance
Associate Advisor
Other advisors: Emeritus Professor Stuart Crozier, Professor Feng Liu
Media
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