Dr

Darren Korbie

Email: 
Phone: 
+61 7 334 64171

Availability

Dr Darren Korbie is:
Available for supervision

Qualifications

  • Bachelor of Science, McMaster University
  • Doctor of Philosophy, The University of Queensland

Search Professor Darren Korbie’s works on UQ eSpace

56 works between 2008 and 2024
All (56) Journal Article (48) Book Chapter (3) Conference Publication (4) Other Outputs (1)

21 - 40 of 56 works

2019

Conference Publication

Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer

Schmid, P., Pinder, S., Wheatley, D., Zummit, C., Macaskill, E. J., Hu, J., Price, R., Bundred, N., Hadad, S., Shia, A., Sarker, S-J, Lim, L., Mousa, K., O'Brien, C., Wilson, T. R., Lackner, M. R., Gendreau, S., Gazinska, P., Korbie, D., Trau, M., Mainwaring, P., Thompson, A. and Purushotham, A. (2019). Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer. San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P2-08-02

Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer

2019

Journal Article

PrimerROC: accurate condition-independent dimer prediction using ROC analysis

Johnston, Andrew D., Lu, Jennifer, Ru, Ke-lin, Korbie, Darren and Trau, Matt (2019). PrimerROC: accurate condition-independent dimer prediction using ROC analysis. Scientific Reports, 9 (1) 209, 209. doi: 10.1038/s41598-018-36612-9

PrimerROC: accurate condition-independent dimer prediction using ROC analysis

2019

Journal Article

Tracking antigen specific T-cells: technological advancement and limitations

Dey, Shuvashis, Kamil Reza, K., Wuethrich, Alain, Korbie, Darren, Ibn Sina, Abu Ali and Trau, Matt (2019). Tracking antigen specific T-cells: technological advancement and limitations. Biotechnology Advances, 37 (1), 145-153. doi: 10.1016/j.biotechadv.2018.11.010

Tracking antigen specific T-cells: technological advancement and limitations

2018

Journal Article

Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker

Sina, Abu Ali Ibn, Carrascosa, Laura G., Liang, Ziyu, Grewal, Yadveer S., Wardiana, Andri, Shiddiky, Muhammad J. A., Gardiner, Robert A., Samaratunga, Hemamali, Gandhi, Maher K., Scott, Rodney J., Korbie, Darren and Trau, Matt (2018). Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker. Nature Communications, 9 (1) 4915, 4915. doi: 10.1038/s41467-018-07214-w

Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker

2018

Journal Article

A SERS microfluidic platform for targeting multiple soluble immune checkpoints

Reza, K. Kamil, Sina, Abu Ali Ibn, Wuethrich, Alain, Grewal, Yadveer S., Howard, Christopher B., Korbie, Darren and Trau, Matt (2018). A SERS microfluidic platform for targeting multiple soluble immune checkpoints. Biosensors and Bioelectronics, 126, 178-186. doi: 10.1016/j.bios.2018.10.044

A SERS microfluidic platform for targeting multiple soluble immune checkpoints

2018

Journal Article

MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer

Milevskiy, Michael J. G., Sandhu, Gurveen K., Wronski, Anna, Korbie, Darren, Brewster, Brooke L., Shewan, Annette, Edwards, Stacey L., French, Juliet D. and Brown, Melissa A. (2018). MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer. Oncotarget, 9 (71), 33577-33588. doi: 10.18632/oncotarget.26094

MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer

2018

Journal Article

Parallel profiling of cancer cells and proteins using a graphene oxide functionalized ac-EHD SERS immunoassay

Reza, K. Kamil, Dey, Shuvashis, Wuethrich, Alain, Sina, Abu Ali Ibn, Korbie, Darren, Wang, Yuling and Trau, Matt (2018). Parallel profiling of cancer cells and proteins using a graphene oxide functionalized ac-EHD SERS immunoassay. Nanoscale, 10 (39), 18482-18491. doi: 10.1039/c8nr02886a

Parallel profiling of cancer cells and proteins using a graphene oxide functionalized ac-EHD SERS immunoassay

2018

Journal Article

Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges

Lane, R. E., Korbie, D., Hill, M. M. and Trau, M. (2018). Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges. Clinical and Translational Medicine, 7 (1) 14, 14. doi: 10.1186/s40169-018-0192-7

Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges

2018

Conference Publication

When focal therapy fails for localised prostate cancer - can epigenetics predict which patients fail and improve patient selection?

Blazevski, Alexandar, Pidsley, Ruth, Qu, Wenjia, Korbie, Darren, Luu, Loi, Chang, John, Yuen, Brian, Scheltema, Matthijs J., Masand, Natasha, Haynes, Anne-Maree, Quoc Nguyen,, Stirzaker, Clare, Song, Jenny, Stricker, Phillip and Clark, Susan (2018). When focal therapy fails for localised prostate cancer - can epigenetics predict which patients fail and improve patient selection?. ANZUP Annual Scientific Meeting, Putting People First, Sydney, NSW, Australia, 8–10 July 2018. Hoboken, NJ, United States: Wiley.

When focal therapy fails for localised prostate cancer - can epigenetics predict which patients fail and improve patient selection?

2017

Journal Article

A multiplex microplatform for the detection of multiple DNA methylation events using gold-DNA affinity

Ibn Sina, Abu Ali, Foster, Matthew Thomas, Korbie, Darren, Carrascosa, Laura G., Shiddiky, Muhammad J. A., Gao, Jing, Dey, Shuvashis and Trau, Matt (2017). A multiplex microplatform for the detection of multiple DNA methylation events using gold-DNA affinity. Analyst, 142 (19), 3573-3578. doi: 10.1039/c7an00611j

A multiplex microplatform for the detection of multiple DNA methylation events using gold-DNA affinity

2017

Journal Article

Detection of aberrant protein phosphorylation in cancer using direct gold-protein affinity interactions

Ahmed, Mostak, Carrascosa, Laura G., Ibn Sina, Abu Ali, Zarate, Ester Marina, Korbie, Darren, Ru, Ke-lin, Shiddiky, Muhammad J. A., Mainwaring, Paul and Trau, Matt (2017). Detection of aberrant protein phosphorylation in cancer using direct gold-protein affinity interactions. Biosensors and Bioelectronics, 91, 8-14. doi: 10.1016/j.bios.2016.12.012

Detection of aberrant protein phosphorylation in cancer using direct gold-protein affinity interactions

2017

Journal Article

Evaluation of different oligonucleotide base substitutions at CpG binding sites in multiplex bisulfite-PCR sequencing

Lu, Jennifer, Ru, Kelin, Candiloro, Ida, Dobrovic, Alexander, Korbie, Darren and Trau, Matt (2017). Evaluation of different oligonucleotide base substitutions at CpG binding sites in multiplex bisulfite-PCR sequencing. Scientific Reports, 7 (1) 45096, 45096. doi: 10.1038/srep45096

Evaluation of different oligonucleotide base substitutions at CpG binding sites in multiplex bisulfite-PCR sequencing

2017

Journal Article

PrimerSuite: a high-throughput web-based primer design program for multiplex bisulfite PCR

Lu, Jennifer, Johnston, Andrew, Berichon, Philippe, Ru, Ke-lin, Korbie, Darren and Trau, Matt (2017). PrimerSuite: a high-throughput web-based primer design program for multiplex bisulfite PCR. Scientific Reports, 7 (1) 41328, 41328. doi: 10.1038/srep41328

PrimerSuite: a high-throughput web-based primer design program for multiplex bisulfite PCR

2017

Book Chapter

Purification protocols for extracellular vesicles

Lane, Rebecca E., Korbie, Darren, Trau, Matt and Hill, Michelle M. (2017). Purification protocols for extracellular vesicles. Extracellular vesicles: methods and protocols. (pp. 111-130) edited by Winston Patrick Kuo and Shidong Jia. New York, United States: Humana Press. doi: 10.1007/978-1-4939-7253-1_10

Purification protocols for extracellular vesicles

2016

Journal Article

Rapid molecular profiling of myeloproliferative neoplasms using targeted Exon Resequencing of 86 genes involved in JAK-STAT signaling and epigenetic regulation

Magor, Graham W., Tallack, Michael R., Klose, Nathan M., Taylor, Debra, Korbie, Darren, Mollee, Peter, Trau, Matt and Perkins, Andrew C. (2016). Rapid molecular profiling of myeloproliferative neoplasms using targeted Exon Resequencing of 86 genes involved in JAK-STAT signaling and epigenetic regulation. Journal of Molecular Diagnostics, 18 (5), 707-718. doi: 10.1016/j.jmoldx.2016.05.006

Rapid molecular profiling of myeloproliferative neoplasms using targeted Exon Resequencing of 86 genes involved in JAK-STAT signaling and epigenetic regulation

2016

Journal Article

Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer

Schmid, Peter, Pinder, Sarah E., Wheatley, Duncan, Macaskill, Jane, Zammit, Charles, Hu, Jennifer, Price, Robert, Bundred, Nigel, Hadad, Sirwan, Shia, Alice, Sarker, Shah-Jalal, Lim, Louise, Gazinska, Patrycja, Woodman, Natalie, Korbie, Darren, Trau, Matt, Mainwaring, Paul, Gendreau, Steven, Lackner, Mark R., Derynck, Mika, Wilson, Timothy R., Butler, Hannah, Earl, Gemma, Parker, Peter, Purushotham, Arnie and Thompson, Alastair (2016). Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer. Journal of Clinical Oncology, 34 (17), 1987-1994. doi: 10.1200/JCO.2015.63.9179

Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer

2016

Journal Article

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing

Wong, Nicholas C., Pope, Bernard J., Candiloro, Ida L., Korbie, Darren, Trau, Matt, Wong, Stephen Q., Mikeska, Thomas, Zhang, Xinmin Z, Pitman, Mark, Eggers, Stefanie, Doyle, Stephen R and Dobrovic, Alexander (2016). MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing. BMC Bioinformatics, 17 (1) 98, 98.1-98.14. doi: 10.1186/s12859-016-0950-8

MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing

2016

Journal Article

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer

French, Juliet D., Johnatty, Sharon E., Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J., Russell, Amanda J., Kar, Siddhartha, Chen, Xiaoging, Hillman, Kristine M., Kaufmann, S, Sivakumaran H., O'Reilly, Martin, Wang, Chen, Korbie, Darren J., Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandra, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander ... MacGregor, Stuart (2016). Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. Oncotarget, 7 (6), 6353-6368. doi: 10.18632/oncotarget.7047

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer

2016

Book Chapter

Methods used for noncoding RNAs analysis

Askarian-Amiri, Marjan E., Korbie, Darren J., Sarkar, Debina and Finlay, Graeme (2016). Methods used for noncoding RNAs analysis. Molecular pathology in cancer research. (pp. 151-175) edited by Sunil R. Lakhani and Stephen B. Fox. New York, U.S.A.: Springer . doi: 10.1007/978-1-4939-6643-1_8

Methods used for noncoding RNAs analysis

2015

Journal Article

Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat

Wong, Nicholas C., Pope, Bernard J., Candiloro, Ida, Korbie, Darren, Trau, Matt, Wong, Stephen Q., Mikeska, Thomas, van Denderen, Bryce J. W., Thompson, Erik W., Eggers, Stefanie, Doyle, Stephen R. and Dobrovic, Alexander (2015). Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat. Gigascience, 4 (1) 55, 55.1-55.8. doi: 10.1186/s13742-015-0098-x

Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat

Current funding

  • 2022 - 2024
    Novel epigenetic blood test for breast cancer detection and monitoring (National Breast Cancer Foundation Grant administered by UNSW)
    University of New South Wales
    Open grant

Past funding

  • 2018 - 2021
    Genomics markers in breast cancer
    Queen Mary University of London
    Open grant
  • 2018 - 2021
    DNA exhibits new self-assembled structures due to clustered DNA methylation
    ARC Discovery Projects
    Open grant
  • 2018 - 2022
    Integrating immunity and genetics in Follicular Lymphoma to establish a prognostic score fit for the modern era
    NHMRC Project Grant
    Open grant
  • 2017 - 2018
    Translating epigenetic biomarkers into a pan-cancer diagnostics
    UQ Early Career Researcher
    Open grant
  • 2016 - 2017
    QMUL Research Project 1
    Queen Mary University of London
    Open grant
  • 2016
    Exosome and Bio/Nanoparticle Characterisation Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    An intergrated fluidic circuit system for digital PCR analysis, single-cell gene- expression, and high-throughput preparation of next-generation sequencing libraries.
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Dr Darren Korbie is:
Available for supervision

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Supervision history

Completed supervision

Enquiries

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