Dr

Darren Korbie

Email: 
Phone: 
+61 7 334 64171

Availability

Dr Darren Korbie is:
Available for supervision

Qualifications

  • Bachelor of Science, McMaster University
  • Doctor of Philosophy, The University of Queensland

Search Professor Darren Korbie’s works on UQ eSpace

56 works between 2008 and 2024
All (56) Journal Article (48) Book Chapter (3) Conference Publication (4) Other Outputs (1)

41 - 56 of 56 works

2015

Journal Article

DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer

Stone, Andrew, Zotenko, Elena, Locke, Warwick J., Korbie, Darren, Millar, Ewan K. A., Pidsley, Ruth, Stirzaker, Clare, Graham, Peter, Trau, Matt, Musgrove, Elizabeth A., Nicholson, Robert I., Gee, Julia M. W. and Clark, Susan J. (2015). DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer. Nature Communications, 6 (1) 7758, 7758.1-7758.9. doi: 10.1038/ncomms8758

DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer

2015

Journal Article

Observations of tunable resistive pulse sensing for exosome analysis: improving system sensitivity and stability

Anderson, Will, Lane, Rebecca, Korbie, Darren and Trau, Matt (2015). Observations of tunable resistive pulse sensing for exosome analysis: improving system sensitivity and stability. Langmuir, 31 (23), 6577-6587. doi: 10.1021/acs.langmuir.5b01402

Observations of tunable resistive pulse sensing for exosome analysis: improving system sensitivity and stability

2015

Journal Article

Multi-platform quality assurance (QA) comparison of next-generation sequencing (NGS) technologies incorporating novel simultaneous mutation and copy number variation (CNV) reporting

Mainwaring, Paul N., Pyke, Christopher, Korbie, Darren, Pheasant, Michael, Gascoigne, Dennis, Musgrave, Ken, O'Neill, Kate, McGrath, Kelly and Trau, Mattias (2015). Multi-platform quality assurance (QA) comparison of next-generation sequencing (NGS) technologies incorporating novel simultaneous mutation and copy number variation (CNV) reporting. Journal of Clinical Oncology, 33 (15_suppl), e22126-e22126. doi: 10.1200/jco.2015.33.15_suppl.e22126

Multi-platform quality assurance (QA) comparison of next-generation sequencing (NGS) technologies incorporating novel simultaneous mutation and copy number variation (CNV) reporting

2015

Journal Article

Multiplex bisulfite PCR resequencing of clinical FFPE DNA

Korbie, Darren, Lin, Erica, Wall, David, Nair, Shalima S., Stirzaker, Clare, Clark, Sue J. and Trau, Matt (2015). Multiplex bisulfite PCR resequencing of clinical FFPE DNA. Clinical Epigenetics, 7 (28) 28, 1-11. doi: 10.1186/s13148-015-0067-3

Multiplex bisulfite PCR resequencing of clinical FFPE DNA

2015

Journal Article

Methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value

Stirzaker, Clare, Zotenko, Elena, Song, Jenny Z., Qu, Wenja, Nair, Shalima, Locke, Warwick J., Stone, Andrew Stone, Armstrong, Nicola J., Robinson, Mark D., Dobrovic, Alexander, Avery-Kiejda, Kelly A., Peters, Kate M., French, Juliet D., Stein, Sandra, Korbie, Darren J., Trau, Matt, Forbes, John F., Scott, Rodney J., Brown, Melissa A., Francis, Glenn D. and Clark, Susan J. (2015). Methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value. Nature Communications, 6 (5899) 5899, 1-11. doi: 10.1038/ncomms6899

Methylome sequencing in triple negative breast cancer reveals distinct methylation clusters with prognostic value

2015

Journal Article

Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing

Lane, Rebecca E., Korbie, Darren, Anderson, Will, Vaidyanathan, Ramanathan and Trau, Matt (2015). Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing. Scientific Reports, 5 (1) 7639, 7639.1-7639.7. doi: 10.1038/srep07639

Analysis of exosome purification methods using a model liposome system and tunable-resistive pulse sensing

2014

Journal Article

Detecting exosomes specifically: a multiplexed device based on alternating current electrohydrodynamic induced nanoshearing

Vaidyanathan, Ramanathan, Naghibosadat, Maedeh, Rauf, Sakandar, Korbie, Darren, Carrascosa, Laura G., Shiddiky, Muhammad J. A. and Trau, Matt (2014). Detecting exosomes specifically: a multiplexed device based on alternating current electrohydrodynamic induced nanoshearing. Analytical Chemistry, 86 (22), 11125-11132. doi: 10.1021/ac502082b

Detecting exosomes specifically: a multiplexed device based on alternating current electrohydrodynamic induced nanoshearing

2014

Conference Publication

Detecting Exosomes Specifically: a Microfluidic Approach Based on Alternating Current Electrohydrodynamic Induced Nanoshearing

Shiddiky, Muhammad J, Vaidyanathan, Ramanathan, Naghibosadat, Maedeh, Rauf, Sakandar, Korbie, Darren, Carrascosa, Laura G and Trau, Matt (2014). Detecting Exosomes Specifically: a Microfluidic Approach Based on Alternating Current Electrohydrodynamic Induced Nanoshearing. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, San Antonio, TX United States, 26-30 October 2014. San Antonio, TX United States: MicroTAS.

Detecting Exosomes Specifically: a Microfluidic Approach Based on Alternating Current Electrohydrodynamic Induced Nanoshearing

2013

Journal Article

MicroRNAs-140-5p/140-3p modulate leydig cell numbers in the developing mouse testis

Rakoczy, Joanna, Fernandez-Valverde, Selene L., Glazov, Evgeny A., Wainwright, Elanor N., Sato, Tempei, Takada, Shuji, Combes, Alexander N., Korbie, Darren J., Miller, David, Grimmond, Sean M., Little, Melissa H., Asahara, Hiroshi, Mattick, John S., Taft, Ryan J. and Wilhelm, Dagmar (2013). MicroRNAs-140-5p/140-3p modulate leydig cell numbers in the developing mouse testis. Biology of Reproduction, 88 (6) 143, 143. doi: 10.1095/biolreprod.113.107607

MicroRNAs-140-5p/140-3p modulate leydig cell numbers in the developing mouse testis

2011

Other Outputs

The identification and characterization of novel RNAs in the mouse transcriptome

Darren Korbie (2011). The identification and characterization of novel RNAs in the mouse transcriptome. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland.

The identification and characterization of novel RNAs in the mouse transcriptome

2011

Journal Article

Expression of distinct RNAs from 3′ untranslated regions

Mercer, Tim R., Wilhelm, Dagmar, Dinger, Marcel E., Solda, Giulia, Korbie, Darren J., Glazov, Evgeny A., Truong, Vy, Schwenke, Maren, Simons, Cas, Matthaei, Klaus I., Saint, Robert, Koopman, Peter and Mattick, John S. (2011). Expression of distinct RNAs from 3′ untranslated regions. Nucleic Acids Research, 39 (6), 2393-2403. doi: 10.1093/nar/gkq1158

Expression of distinct RNAs from 3′ untranslated regions

2010

Journal Article

Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome

Mercer, Tim R., Dinger, Marcel E., Bracken, Cameron P., Kolle, Gabriel, Szubert, Jan M., Korbie, Darren J., Askarian-Amiri, Marjan E., Gardiner, Brooke B., Goodall, Gregory J., Grimmond, Sean M. and Mattick, John S. (2010). Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome. Genome Research, 20 (12), 1639-1650. doi: 10.1101/gr.112128.110

Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome

2010

Journal Article

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans

Taft, Ryan, Simons, Cas, Nahkuri, Satu, Oey, Harald, Korbie, Darren J., Mercer, Timothy R., Holst, Jeff, Ritchie, William, Wong, Justin J-L., Rasko, John E. J., Rokhsar, Daniel S., Degnan, Bernard M. and Mattick, John S. (2010). Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature Structural and Molecular Biology, 17 (8), 1030-1035. doi: 10.1038/nsmb.1841

Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans

2010

Journal Article

Identification of novel non-coding RNAs using profiles of short sequence reads from next generation sequencing data

Jung, Chol-Hee, Hansen, Martin A., Makunin, Igor V., Korbie, Darren J. and Mattick, John S. (2010). Identification of novel non-coding RNAs using profiles of short sequence reads from next generation sequencing data. BMC Genomics, 11 (1 Article # 77) 77, 1-12. doi: 10.1186/1471-2164-11-77

Identification of novel non-coding RNAs using profiles of short sequence reads from next generation sequencing data

2008

Journal Article

Touchdown PCR for increased specificity and sensitivity in PCR amplification

Korbie, D. J. and Mattick, J. S. (2008). Touchdown PCR for increased specificity and sensitivity in PCR amplification. Nature Protocols, 3 (9), 1452-1456. doi: 10.1038/nprot.2008.133

Touchdown PCR for increased specificity and sensitivity in PCR amplification

2008

Journal Article

Molecular evolution of the HBII-52 snoRNA Cluster

Nahkuri, S., Taft, R. J., Korbie, D. J. and Mattick, J. S. (2008). Molecular evolution of the HBII-52 snoRNA Cluster. Journal of Molecular Biology, 381 (4), 810-815. doi: 10.1016/j.jmb.2008.06.057

Molecular evolution of the HBII-52 snoRNA Cluster

Current funding

  • 2022 - 2024
    Novel epigenetic blood test for breast cancer detection and monitoring (National Breast Cancer Foundation Grant administered by UNSW)
    University of New South Wales
    Open grant

Past funding

  • 2018 - 2021
    Genomics markers in breast cancer
    Queen Mary University of London
    Open grant
  • 2018 - 2021
    DNA exhibits new self-assembled structures due to clustered DNA methylation
    ARC Discovery Projects
    Open grant
  • 2018 - 2022
    Integrating immunity and genetics in Follicular Lymphoma to establish a prognostic score fit for the modern era
    NHMRC Project Grant
    Open grant
  • 2017 - 2018
    Translating epigenetic biomarkers into a pan-cancer diagnostics
    UQ Early Career Researcher
    Open grant
  • 2016 - 2017
    QMUL Research Project 1
    Queen Mary University of London
    Open grant
  • 2016
    Exosome and Bio/Nanoparticle Characterisation Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    An intergrated fluidic circuit system for digital PCR analysis, single-cell gene- expression, and high-throughput preparation of next-generation sequencing libraries.
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Dr Darren Korbie is:
Available for supervision

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Supervision history

Completed supervision

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