Overview
Background
Dr Karan Gulati is a Research Group Leader and the Deputy Director of Research at the School of Dentistry, UQ. He is also the Deputy Director of Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3) at UQ Dentistry.
Dr Gulati is a pioneer in electrochemically nano-engineered dental implants with over 13 years of extensive research experience using nano-engineering towards various bioactive and therapeutic applications. Dr Gulati completed his PhD from the University of Adelaide (Australia) in 2015 and was awarded the Dean’s Commendation for Doctoral Thesis Excellence. His career has been supported by prestigious fellowships from NHMRC (National Health and Medical Research Council, Australia), JSPS (Japan Society for the Promotion of Science, Japan), Erasmus+ (Germany) and the University of Queensland. At 8 years post-PhD, Dr Gulati has edited 3 books, published 7 chapters and >72 publications (h-index 35), and presented >110 times in various reputed conferences.
Availability
- Dr Karan Gulati is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Adelaide
Research impacts
The trans-mucosal nature of dental implants presents a unique challenge from a biomaterial perspective, requiring rapid establishment and maintenance of osseointegration in the alveolar bone of varying quantity and quality and the formation of resilient, soft tissue integration. Key challenges in achieving long-term dental implant success include sub-optimal osseointegration, soft-tissue integration, immunomodulation and onset of bacterial infection.
Dental implant surfaces have been enhanced via mechanical, chemical, and biological modifications to manage the complex therapeutic requirements of the dental microenvironment. Among these, nanotubes (NTs) or nanopores (NPs) engineered on implant surfaces (Ti, Zr, NiTi, Ti64 alloys, dental/orthopaedic/craniofacial implants) using electrochemical anodisation present considerable therapeutic potential due to several favourable properties, including enhanced integration, tailorable drug loading/release and mechano-transduction.
Dr. Gulati’s research group GATORs (Group for Anodized Therapies for Osseointegration, Regeneration and Stimulation) focus on the developments and challenges associated with nano-engineered implants, focusing on generating tailorable devices that can address the unique challenges related to biomedical implants.
Works
Search Professor Karan Gulati’s works on UQ eSpace
2021
Journal Article
Bed of nails: bioinspired nano-texturing towards antibacterial and bioactivity functions
Chopra, D., Gulati, K. and Ivanovski, S. (2021). Bed of nails: bioinspired nano-texturing towards antibacterial and bioactivity functions. Materials Today Advances, 12 100176, 100176. doi: 10.1016/j.mtadv.2021.100176
2021
Journal Article
Influence of sterilization on the performance of anodized nanoporous titanium implants
Guo, Tianqi, Oztug, Necla Asli Kocak, Han, Pingping, Ivanovski, Saso and Gulati, Karan (2021). Influence of sterilization on the performance of anodized nanoporous titanium implants. Materials Science and Engineering: C, 130 112429, 112429. doi: 10.1016/j.msec.2021.112429
2021
Journal Article
Influence of bioinspired lithium-doped titanium implants on gingival fibroblast bioactivity and biofilm adhesion
Alali, Aya Q., Abdal-hay, Abdalla, Gulati, Karan, Ivanovski, Sašo, Fournier, Benjamin P. J. and Lee, Ryan S. B. (2021). Influence of bioinspired lithium-doped titanium implants on gingival fibroblast bioactivity and biofilm adhesion. Nanomaterials, 11 (11) 2799, 2799. doi: 10.3390/nano11112799
2021
Journal Article
Dental implant nano-engineering: advances, limitations and future directions
Zhang, Yifan, Gulati, Karan, Li, Ze, Di, Ping and Liu, Yan (2021). Dental implant nano-engineering: advances, limitations and future directions. Nanomaterials, 11 (10) 2489, 2489. doi: 10.3390/nano11102489
2021
Journal Article
Research to clinics: clinical translation considerations for anodized nano-engineered titanium implants
Gulati, Karan, Zhang, Yifan, Di, Ping, Liu, Yan and Ivanovski, Sašo (2021). Research to clinics: clinical translation considerations for anodized nano-engineered titanium implants. ACS Biomaterials Science and Engineering, 8 (10), 4077-4091. doi: 10.1021/acsbiomaterials.1c00529
2021
Journal Article
Periodontal and dental pulp cell-derived small extracellular vesicles: a review of the current status
Hua, Shu, Bartold, Peter Mark, Gulati, Karan, Moran, Corey Stephen, Ivanovski, Sašo and Han, Pingping (2021). Periodontal and dental pulp cell-derived small extracellular vesicles: a review of the current status. Nanomaterials, 11 (7) 1858, 1-34. doi: 10.3390/nano11071858
2021
Journal Article
Double-edged sword: therapeutic efficacy versus toxicity evaluations of doped titanium implants
Gulati, Karan, Scimeca, Jean-Claude, Ivanovski, Sašo and Verron, Elise (2021). Double-edged sword: therapeutic efficacy versus toxicity evaluations of doped titanium implants. Drug Discovery Today, 26 (11), 2734-2742. doi: 10.1016/j.drudis.2021.07.004
2021
Journal Article
Micro + Nano: conserving the gold standard microroughness to nanoengineer zirconium dental implants
Chopra, Divya, Gulati, Karan and Ivanovski, Sašo (2021). Micro + Nano: conserving the gold standard microroughness to nanoengineer zirconium dental implants. ACS Biomaterials Science and Engineering, 7 (7) acsbiomaterials.1c00356, 3069-3074. doi: 10.1021/acsbiomaterials.1c00356
2021
Journal Article
Understanding and optimizing the antibacterial functions of anodized nano-engineered titanium implants
Chopra, Divya, Gulati, Karan and Ivanovski, Sašo (2021). Understanding and optimizing the antibacterial functions of anodized nano-engineered titanium implants. Acta Biomaterialia, 127, 80-101. doi: 10.1016/j.actbio.2021.03.027
2021
Journal Article
Race to invade: Understanding soft tissue integration at the transmucosal region of titanium dental implants
Guo, Tianqi, Gulati, Karan, Arora, Himanshu, Han, Pingping, Fournier, Benjamin and Ivanovski, Sašo (2021). Race to invade: Understanding soft tissue integration at the transmucosal region of titanium dental implants. Dental Materials, 37 (5), 816-831. doi: 10.1016/j.dental.2021.02.005
2021
Journal Article
Towards clinical translation: optimized fabrication of controlled nanostructures on implant-relevant curved zirconium surfaces
Chopra, Divya, Gulati, Karan and Ivanovski, Sašo (2021). Towards clinical translation: optimized fabrication of controlled nanostructures on implant-relevant curved zirconium surfaces. Nanomaterials, 11 (4) 868, 868. doi: 10.3390/nano11040868
2021
Journal Article
ON or OFF: Triggered therapies from anodized nano-engineered titanium implants
Jayasree, Anjana, Ivanovski, Sašo and Gulati, Karan (2021). ON or OFF: Triggered therapies from anodized nano-engineered titanium implants. Journal of Controlled Release, 333, 521-535. doi: 10.1016/j.jconrel.2021.03.020
2021
Journal Article
Old is gold: electrolyte aging influences the topography, chemistry, and bioactivity of anodized TiO2 nanopores
Guo, Tianqi, Oztug, Necla Asli Kocak, Han, Pingping, Ivanovski, Sašo and Gulati, Karan (2021). Old is gold: electrolyte aging influences the topography, chemistry, and bioactivity of anodized TiO2 nanopores. ACS Applied Materials and Interfaces, 13 (7) acsami.0c19569, 7897-7912. doi: 10.1021/acsami.0c19569
2021
Journal Article
Orchestrating soft tissue integration at the transmucosal region of titanium implants
Guo, Tianqi, Gulati, Karan, Arora, Himanshu, Han, Pingping, Fournier, Benjamin and Ivanovski, Sašo (2021). Orchestrating soft tissue integration at the transmucosal region of titanium implants. Acta Biomaterialia, 124, 33-49. doi: 10.1016/j.actbio.2021.01.001
2020
Journal Article
Determining the relative importance of titania nanotubes characteristics on bone implant surface performance: a quality by design study with a fuzzy approach
Martinez-Marquez, Daniel, Gulati, Karan, Carty, Christopher P., Stewart, Rodney A. and Ivanovski, Sašo (2020). Determining the relative importance of titania nanotubes characteristics on bone implant surface performance: a quality by design study with a fuzzy approach. Materials Science and Engineering: C, 114 110995, 110995. doi: 10.1016/j.msec.2020.110995
2020
Journal Article
Anodized anisotropic titanium surfaces for enhanced guidance of gingival fibroblasts
Gulati, Karan, Moon, Ho-Jin, Kumar, P.T. Sudheesh, Han, Pingping and Ivanovski, Sašo (2020). Anodized anisotropic titanium surfaces for enhanced guidance of gingival fibroblasts. Materials Science and Engineering: C, 112 110860, 110860. doi: 10.1016/j.msec.2020.110860
2020
Journal Article
Therapeutic outcomes of non-grafted and platelet concentrations-grafted transcrestal maxillary sinus elevation (TSFE): a systematic review and meta-analysis
Guo, Tianqi, Gulati, Karan, Shen, Ziyun, Han, Pingping and Fan, Zhen (2020). Therapeutic outcomes of non-grafted and platelet concentrations-grafted transcrestal maxillary sinus elevation (TSFE): a systematic review and meta-analysis. Scientific Reports, 10 (1) 5935, 5935. doi: 10.1038/s41598-020-62407-y
2020
Journal Article
In situ hydrothermal transformation of titanium surface into lithium-doped continuous nanowire network towards augmented bioactivity
Abdal-hay, Abdalla, Gulati, Karan, Fernandez-Medina, Tulio, Qian, Ma and Ivanovski, Saso (2020). In situ hydrothermal transformation of titanium surface into lithium-doped continuous nanowire network towards augmented bioactivity. Applied Surface Science, 505 144604, 144604. doi: 10.1016/j.apsusc.2019.144604
2020
Journal Article
Role of offset and gradient architectures of 3-D melt electrowritten scaffold on differentiation and mineralization of osteoblasts
Abbasi, Naghmeh, Ivanovski, Saso, Gulati, Karan, Love, Robert M. and Hamlet, Stephen (2020). Role of offset and gradient architectures of 3-D melt electrowritten scaffold on differentiation and mineralization of osteoblasts. Biomaterials Research, 24 (1) 2, 2. doi: 10.1186/s40824-019-0180-z
2018
Journal Article
Bridging the gap: optimized fabrication of robust titania nanostructures on complex implant geometries towards clinical translation
Li, Tao, Gulati, Karan, Wang, Na, Zhang, Zhenting and Ivanovski, Sašo (2018). Bridging the gap: optimized fabrication of robust titania nanostructures on complex implant geometries towards clinical translation. Journal of Colloid and Interface Science, 529, 452-463. doi: 10.1016/j.jcis.2018.06.004
Funding
Supervision
Availability
- Dr Karan Gulati is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Single Cell Force Signature of Nano-Engineered Implants
Principal Advisor
Other advisors: Professor Saso Ivanovski
Completed supervision
-
2023
Doctor Philosophy
Nano-Engineered Titanium Dental Implants for Tailored Therapy and Bioactivity
Principal Advisor
Other advisors: Professor Saso Ivanovski
-
2023
Doctor Philosophy
Fabrication Optimization of Bioactive Nano-Engineered Titanium Dental Implants
Principal Advisor
Other advisors: Professor Saso Ivanovski, Dr Pingping Han
Media
Enquiries
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