Overview
Background
Dr Karan Gulati is a Research Group Leader and the Deputy Director of Research at the School of Dentistry, UQ. He is also the Deputy Director of Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3) at UQ Dentistry.
Dr Gulati is a pioneer in electrochemically nano-engineered dental implants with over 13 years of extensive research experience using nano-engineering towards various bioactive and therapeutic applications. Dr Gulati completed his PhD from the University of Adelaide (Australia) in 2015 and was awarded the Dean’s Commendation for Doctoral Thesis Excellence. His career has been supported by prestigious fellowships from NHMRC (National Health and Medical Research Council, Australia), JSPS (Japan Society for the Promotion of Science, Japan), Erasmus+ (Germany) and the University of Queensland. At 8 years post-PhD, Dr Gulati has edited 3 books, published 7 chapters and >72 publications (h-index 35), and presented >110 times in various reputed conferences.
Availability
- Dr Karan Gulati is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Adelaide
Research impacts
The trans-mucosal nature of dental implants presents a unique challenge from a biomaterial perspective, requiring rapid establishment and maintenance of osseointegration in the alveolar bone of varying quantity and quality and the formation of resilient, soft tissue integration. Key challenges in achieving long-term dental implant success include sub-optimal osseointegration, soft-tissue integration, immunomodulation and onset of bacterial infection.
Dental implant surfaces have been enhanced via mechanical, chemical, and biological modifications to manage the complex therapeutic requirements of the dental microenvironment. Among these, nanotubes (NTs) or nanopores (NPs) engineered on implant surfaces (Ti, Zr, NiTi, Ti64 alloys, dental/orthopaedic/craniofacial implants) using electrochemical anodisation present considerable therapeutic potential due to several favourable properties, including enhanced integration, tailorable drug loading/release and mechano-transduction.
Dr. Gulati’s research group GATORs (Group for Anodized Therapies for Osseointegration, Regeneration and Stimulation) focus on the developments and challenges associated with nano-engineered implants, focusing on generating tailorable devices that can address the unique challenges related to biomedical implants.
Works
Search Professor Karan Gulati’s works on UQ eSpace
2012
Journal Article
Local drug delivery to the bone by drug-releasing implants: perspectives of nano-engineered titania nanotube arrays
Gulati, Karan, Aw, Moom Sinn, Findlay, David and Losic, Dusan (2012). Local drug delivery to the bone by drug-releasing implants: perspectives of nano-engineered titania nanotube arrays. Therapeutic Delivery, 3 (7), 857-873. doi: 10.4155/TDE.12.66
2012
Journal Article
Nanoengineered drug-releasing Ti wires as an alternative for local delivery of chemotherapeutics in the brain
Losic, Dusan, Gulati, Karen and Sinn Aw, Moon (2012). Nanoengineered drug-releasing Ti wires as an alternative for local delivery of chemotherapeutics in the brain. International Journal of Nanomedicine, 7, 2069-2076. doi: 10.2147/ijn.s29917
2012
Journal Article
Biocompatible polymer coating of titania nanotube arrays for improved drug elution and osteoblast adhesion
Gulati, Karan, Ramakrishnan, Saminathan, Aw, Moom Sinn, Atkins, Gerald J., Findlay, David M. and Losic, Dusan (2012). Biocompatible polymer coating of titania nanotube arrays for improved drug elution and osteoblast adhesion. Acta Biomaterialia, 8 (1), 449-456. doi: 10.1016/j.actbio.2011.09.004
2012
Journal Article
Characterization of drug-release kinetics in trabecular bone from titania nanotube implants
Aw, Moom Sinn, Khalid, Kamarul A., Gulati, Karan, Atkins, Gerald J., Pivonka, Peter, Findlay, David M. and Losic, Dusan (2012). Characterization of drug-release kinetics in trabecular bone from titania nanotube implants. International Journal of Nanomedicine, 7, 4883-4892. doi: 10.2147/IJN.S33655
2011
Journal Article
Drug-eluting Ti wires with titania nanotube arrays for bone fixation and reduced bone infection
Gulati, Karan, Aw, Moom Sinn and Losic, Dusan (2011). Drug-eluting Ti wires with titania nanotube arrays for bone fixation and reduced bone infection. Nanoscale Research Letters, 6 (1) 571, 1-6. doi: 10.1186/1556-276X-6-571
2011
Conference Publication
Self-ordering electrochemistry: a simple approach for engineering nanopore and nanotube arrays for emerging applications
Losic, Dusan, Velleman, Leonara, Kant, Krishna, Kumeria, Tushar, Gulati, Karan, Shapter, Joe G., Beattie, David A. and Simovic, Spomenka (2011). Self-ordering electrochemistry: a simple approach for engineering nanopore and nanotube arrays for emerging applications. 39th International Conference on Coordination Chemistry, Adelaide, SA Australia, 24-30 July 2010. Clayton, VIC Australia: CSIRO Publishing. doi: 10.1071/CH10398
2011
Journal Article
Controlling Drug Release from Titania Nanotube Arrays Using Polymer Nanocarriers and Biopolymer Coating
Aw, Moom Sinn, Gulati, Karan and Losic, Dusan (2011). Controlling Drug Release from Titania Nanotube Arrays Using Polymer Nanocarriers and Biopolymer Coating. Journal of Biomaterials and Nanobiotechnology, 02 (05), 477-484. doi: 10.4236/jbnb.2011.225058
2010
Conference Publication
Highly ordered Titania (TiO2) nanotube arrays fabricated by electrochemical self-ordering process toward development of implantable drug delivery devices with triggered drug release
Gulati, Karan, Simovic, Spomenka and Losic, Dusan (2010). Highly ordered Titania (TiO2) nanotube arrays fabricated by electrochemical self-ordering process toward development of implantable drug delivery devices with triggered drug release. Conference on Optoelectronic and Microelectronic Materials and Devices (COMMAD), Canberra Australia, 12-15 December 2010. New York, NY United States: IEEE. doi: 10.1109/COMMAD.2010.5699716
Funding
Supervision
Availability
- Dr Karan Gulati is:
- Available for supervision
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Supervision history
Completed supervision
-
2023
Doctor Philosophy
Nano-Engineered Titanium Dental Implants for Tailored Therapy and Bioactivity
Principal Advisor
Other advisors: Professor Saso Ivanovski
-
2023
Doctor Philosophy
Fabrication Optimization of Bioactive Nano-Engineered Titanium Dental Implants
Principal Advisor
Other advisors: Professor Saso Ivanovski, Dr Pingping Han
Media
Enquiries
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