Overview
Background
Dr Karan Gulati is a Research Group Leader and the Deputy Director of Research at the School of Dentistry, UQ. He is also the Deputy Director of Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3) at UQ Dentistry.
Dr Gulati is a pioneer in electrochemically nano-engineered dental implants with over 13 years of extensive research experience using nano-engineering towards various bioactive and therapeutic applications. Dr Gulati completed his PhD from the University of Adelaide (Australia) in 2015 and was awarded the Dean’s Commendation for Doctoral Thesis Excellence. His career has been supported by prestigious fellowships from NHMRC (National Health and Medical Research Council, Australia), JSPS (Japan Society for the Promotion of Science, Japan), Erasmus+ (Germany) and the University of Queensland. At 8 years post-PhD, Dr Gulati has edited 3 books, published 7 chapters and >72 publications (h-index 35), and presented >110 times in various reputed conferences.
Availability
- Dr Karan Gulati is:
- Available for supervision
Fields of research
Qualifications
- Doctor of Philosophy, University of Adelaide
Research impacts
The trans-mucosal nature of dental implants presents a unique challenge from a biomaterial perspective, requiring rapid establishment and maintenance of osseointegration in the alveolar bone of varying quantity and quality and the formation of resilient, soft tissue integration. Key challenges in achieving long-term dental implant success include sub-optimal osseointegration, soft-tissue integration, immunomodulation and onset of bacterial infection.
Dental implant surfaces have been enhanced via mechanical, chemical, and biological modifications to manage the complex therapeutic requirements of the dental microenvironment. Among these, nanotubes (NTs) or nanopores (NPs) engineered on implant surfaces (Ti, Zr, NiTi, Ti64 alloys, dental/orthopaedic/craniofacial implants) using electrochemical anodisation present considerable therapeutic potential due to several favourable properties, including enhanced integration, tailorable drug loading/release and mechano-transduction.
Dr. Gulati’s research group GATORs (Group for Anodized Therapies for Osseointegration, Regeneration and Stimulation) focus on the developments and challenges associated with nano-engineered implants, focusing on generating tailorable devices that can address the unique challenges related to biomedical implants.
Works
Search Professor Karan Gulati’s works on UQ eSpace
2018
Journal Article
Titania nanopores with dual micro-/nano-topography for selective cellular bioactivity
Gulati, Karan, Moon, Ho-Jin, Li, Tao, Sudheesh Kumar, P T and Ivanovski, Sašo (2018). Titania nanopores with dual micro-/nano-topography for selective cellular bioactivity. Materials Science and Engineering C: Materials for Biological Applications, 91, 624-630. doi: 10.1016/j.msec.2018.05.075
2018
Journal Article
Consume or conserve: micro-roughness of titanium implants towards fabrication of dual micro-nanotopography
Gulati, Karan, Li, Tao and Ivanovski, Sašo (2018). Consume or conserve: micro-roughness of titanium implants towards fabrication of dual micro-nanotopography. ACS Biomaterials Science and Engineering, 4 (9) acsbiomaterials.8b00829, 3125-3131. doi: 10.1021/acsbiomaterials.8b00829
2018
Journal Article
Understanding and augmenting the stability of therapeutic nanotubes on anodized titanium implants
Li, Tao, Gulati, Karan, Wang, Na, Zhang, Zhenting and Ivanovski, Sašo (2018). Understanding and augmenting the stability of therapeutic nanotubes on anodized titanium implants. Materials Science and Engineering: C, 88, 182-195. doi: 10.1016/j.msec.2018.03.007
2018
Journal Article
Tailoring the immuno-responsiveness of anodized nano-engineered titanium implants
Gulati, Karan, Hamlet, Stephen M. and Ivanovski, Sašo (2018). Tailoring the immuno-responsiveness of anodized nano-engineered titanium implants. Journal of Materials Chemistry B, 6 (18), 2677-2689. doi: 10.1039/c8tb00450a
2018
Journal Article
Green synthesis of three-dimensional hybrid N-doped ORR electro-catalysts derived from apricot sap
Karunagaran, Ramesh, Coghlan, Campbell, Shearer, Cameron, Tran, Diana, Gulati, Karan, Tung, Tran Thanh, Doonan, Christian and Losic, Dusan (2018). Green synthesis of three-dimensional hybrid N-doped ORR electro-catalysts derived from apricot sap. Materials, 11 (2) 205, 205. doi: 10.3390/ma11020205
2018
Conference Publication
Quality by Design towards Standardization of 3D Printed Bone Implants and scaffolds for Industry Translation
Martinez-Marquez, Daniel, Gulati, Karan, Mirnajafizadeh, Ali, Carty, Christopher P., Stewart, Rodney and Ivanovski, Saso (2018). Quality by Design towards Standardization of 3D Printed Bone Implants and scaffolds for Industry Translation. 4th World Congress on Electrical Engineering and Computer Systems and Science, Madrid, Spain, August 21 – 23 2018. Avestia Publishing. doi: 10.11159/icbes18.124
2017
Journal Article
Anodized 3D-printed titanium implants with dual micro- and nano-scale topography promote interaction with human osteoblasts and osteocyte-like cells
Gulati, Karan, Prideaux, Matthew, Kogawa, Masakazu, Lima-Marques, Luis, Atkins, Gerald J., Findlay, David M. and Losic, Dusan (2017). Anodized 3D-printed titanium implants with dual micro- and nano-scale topography promote interaction with human osteoblasts and osteocyte-like cells. Journal of Tissue Engineering and Regenerative Medicine, 11 (12), 3313-3325. doi: 10.1002/term.2239
2017
Journal Article
Estimation of anisotropic permeability in trabecular bone based on microCT imaging and pore-scale fluid dynamics simulations
Daish, C., Blanchard, R., Gulati, K., Losic, D., Findlay, D., Harvie, D. J.E. and Pivonka, P. (2017). Estimation of anisotropic permeability in trabecular bone based on microCT imaging and pore-scale fluid dynamics simulations. Bone Reports, 6, 129-139. doi: 10.1016/j.bonr.2016.12.002
2017
Journal Article
Dental implants modified with drug releasing titania nanotubes: therapeutic potential and developmental challenges
Gulati, Karan and Ivanovski, Saso (2017). Dental implants modified with drug releasing titania nanotubes: therapeutic potential and developmental challenges. Expert Opinion On Drug Delivery, 14 (8), 1009-1024. doi: 10.1080/17425247.2017.1266332
2016
Journal Article
Drug-releasing nano-engineered titanium implants: therapeutic efficacy in 3D cell culture model, controlled release and stability
Gulati, Karan, Kogawa, Masakazu, Prideaux, Matthew, Findlay, David M., Atkins, Gerald J. and Losic, Dusan (2016). Drug-releasing nano-engineered titanium implants: therapeutic efficacy in 3D cell culture model, controlled release and stability. Materials Science and Engineering C: Materials for Biological Applications, 69, 831-840. doi: 10.1016/j.msec.2016.07.047
2016
Journal Article
Titanium wire implants with nanotube arrays: A study model for localized cancer treatment
Kaur, Gagandeep, Willsmore, Tamsyn, Gulati, Karan, Zinonos, Irene, Wang, Ye, Kurian, Mima, Hay, Shelley, Losic, Dusan and Evdokiou, Andreas (2016). Titanium wire implants with nanotube arrays: A study model for localized cancer treatment. Biomaterials, 101, 176-188. doi: 10.1016/j.biomaterials.2016.05.048
2016
Journal Article
Titania nanotubes for orchestrating osteogenesis at the bone-implant interface
Gulati, Karan, Maher, Shaheer, Findlay, David M. and Losic, Dusan (2016). Titania nanotubes for orchestrating osteogenesis at the bone-implant interface. Nanomedicine, 11 (14), 1847-1864. doi: 10.2217/nnm-2016-0169
2016
Journal Article
In situ transformation of chitosan films into microtubular structures on the surface of nanoengineered titanium implants
Gulati, Karan, Johnson, Lucas, Karunagaran, Ramesh, Findlay, David and Losic, Dusan (2016). In situ transformation of chitosan films into microtubular structures on the surface of nanoengineered titanium implants. Biomacromolecules, 17 (4), 1261-1271. doi: 10.1021/acs.biomac.5b01037
2016
Journal Article
Drug diffusion, integration, and stability of nanoengineered drug-releasing implants in bone ex-vivo
Rahman, Shafiur, Gulati, Karan, Kogawa, Masakazu, Atkins, Gerald J., Pivonka, Peter, Findlay, David M. and Losic, Dusan (2016). Drug diffusion, integration, and stability of nanoengineered drug-releasing implants in bone ex-vivo. Journal of Biomedical Materials Research Part A, 104 (3), 714-725. doi: 10.1002/jbm.a.35595
2016
Journal Article
Conversion of titania (TiO2) into conductive titanium (Ti) nanotube arrays for combined drug-delivery and electrical stimulation therapy
Gulati, Karan, Maher, Shaheer, Chandrasekaran, Soundarrajan, Findlay, David M. and Losic, Dusan (2016). Conversion of titania (TiO2) into conductive titanium (Ti) nanotube arrays for combined drug-delivery and electrical stimulation therapy. Journal of Materials Chemistry B, 4 (3), 371-375. doi: 10.1039/c5tb02108a
2015
Journal Article
Synthesis of Carbon Nanotube-Nanotubular Titania Composites by Catalyst-Free CVD Process: Insights into the Formation Mechanism and Photocatalytic Properties
Alsawat, Mohammed, Altalhi, Tariq, Gulati, Karan, Santos, Abel and Losic, Dusan (2015). Synthesis of Carbon Nanotube-Nanotubular Titania Composites by Catalyst-Free CVD Process: Insights into the Formation Mechanism and Photocatalytic Properties. ACS Applied Materials and Interfaces, 7 (51), 28361-28368. doi: 10.1021/acsami.5b08956
2015
Journal Article
Localized drug delivery of selenium (Se) using nanoporous anodic aluminium oxide for bone implants
Saji, Viswanathan S., Kumeria, Tushar, Gulati, Karan, Prideaux, Matthew, Rahman, Shafiur, Alsawat, Mohammed, Santos, Abel, Atkins, Gerald J. and Losic, Dusan (2015). Localized drug delivery of selenium (Se) using nanoporous anodic aluminium oxide for bone implants. Journal of Materials Chemistry B, 3 (35), 7090-7098. doi: 10.1039/c5tb00125k
2015
Journal Article
Optimizing anodization conditions for the growth of titania nanotubes on curved surfaces
Gulati, Karan, Santos, Abel, Findlay, David and Losic, Dusan (2015). Optimizing anodization conditions for the growth of titania nanotubes on curved surfaces. Journal of Physical Chemistry C, 119 (28), 16033-16045. doi: 10.1021/acs.jpcc.5b03383
2015
Journal Article
Advanced biopolymer-coated drug-releasing titania nanotubes (TNTs) implants with simultaneously enhanced osteoblast adhesion and antibacterial properties
Kumeria, Tushar, Mon, Htwe, Aw, Moom Sinn, Gulati, Karan, Santos, Abel, Griesser, Hans J. and Losic, Dusan (2015). Advanced biopolymer-coated drug-releasing titania nanotubes (TNTs) implants with simultaneously enhanced osteoblast adhesion and antibacterial properties. Colloids and Surfaces B: Biointerfaces, 130, 255-263. doi: 10.1016/j.colsurfb.2015.04.021
2015
Journal Article
Titania nanotube arrays for local drug delivery: recent advances and perspectives
Losic, Dusan, Aw, Moom Sinn, Santos, Abel, Gulati, Karan and Bariana, Manpreet (2015). Titania nanotube arrays for local drug delivery: recent advances and perspectives. Expert Opinion on Drug Delivery, 12 (1), 103-127. doi: 10.1517/17425247.2014.945418
Funding
Supervision
Availability
- Dr Karan Gulati is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Single Cell Force Signature of Nano-Engineered Implants
Principal Advisor
Other advisors: Professor Saso Ivanovski
Completed supervision
-
2023
Doctor Philosophy
Nano-Engineered Titanium Dental Implants for Tailored Therapy and Bioactivity
Principal Advisor
Other advisors: Professor Saso Ivanovski
-
2023
Doctor Philosophy
Fabrication Optimization of Bioactive Nano-Engineered Titanium Dental Implants
Principal Advisor
Other advisors: Professor Saso Ivanovski, Dr Pingping Han
Media
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